Extended Data Fig. 2 : Estimated cell composition for blood, muscle, and adipose samples based on DNA methylation deconvolution.
The figure shows estimated adipose, epithelial, fibroblast, and immune cell proportions for blood (Panel A; n=594), muscle (Panel B; n=168), and adipose (Panel C; n=161) tissue samples. For each tissue type, individual points represent individual samples. Proportion of cell types are shown as box and whisker plots showing median (horizontal line), 25th quartile (bottom of the box), 75th quartile (top of the box), and minimum and maximum values within 1.5 × IQR (interquartile range; top and bottom segments, respectively). Adipose cell types are colored in gold, epithelial cells are colored in blue, fibroblasts are colored in seagreen, and immune cells are colored in coral. Estimated cell proportions are based on DNA methylation and the hierarchical EpiDISH deconvolution method described in Zheng et al.67.
