Extended Data Fig. 5: Proportions of variants shared by tissues from the same germ layer.
From: Mitochondrial clonal mosaicism encodes a biphasic molecular clock of aging
This figure displays the proportion of shared mitochondrial variants among tissues originating from the same germ layer (endoderm, mesoderm, ectoderm). These proportions are compared against a null distribution (gray violins) generated by 1000 random permutation of tissue labels, demonstrating a significant enrichment of shared variants within tissues of the same developmental origin. Violin plots illustrate the density distribution of random permutations (null distribution), while overlaid box plots indicate the median (center line), interquartile range (IQR, box limits), and whiskers (extending to 1.5x IQR).
