Fig. 3: Manhattan plot of the multi-trait analysis of GWAS between delirium and Alzheimer disease.
From: Dissecting the genetic and proteomic risk factors for delirium
Delirium-specific MTAG summary statistics are shown. Each point represents a genetic variant. The x axis denotes the variant’s genomic position and the y axis the two-sided P value of the MTAG-adjusted unstandardized effect size estimate in the discovery set. No multiple testing P value adjustments were applied. The gray dashed line denotes the genome-wide significance P value threshold 5 × 10−8. The closest gene in which the lead significant variant is located is annotated. Red highlights the loci ± 1,000 kb around lead variants that replicated. The plot was created using the GWASLab Python package.
