Extended Data Fig. 2: Manhattan plot of delirium GWAS in UKB EUR, conditional on APOE-ε4 haplotype count.
From: Dissecting the genetic and proteomic risk factors for delirium
(Left) Each point represents a genetic variant. The x-axis denotes the variant’s genomic position and the y-axis the GWAS association p value. The gray dashed line denotes the genome-wide significance p value threshold 5×10−8. The closest gene in which the lead significant variant is located is annotated. Orange color highlights loci ±1,000 kb around lead variants. n_cases = 7,176; n_controls = 385,096. (Right) QQ-pot of GWAS observed vs. expected p values. ADAM32: ADAM metallopeptidase domain 32; λgc: genomic inflation factor. The plot was created using the GWASLab python package.
