Extended Data Fig. 4: Spaghetti plots of MMSE (A), CDR-SB (B), and FAQ (C) scores at each visit during the MAD and LTE periods. | Nature Aging

Extended Data Fig. 4: Spaghetti plots of MMSE (A), CDR-SB (B), and FAQ (C) scores at each visit during the MAD and LTE periods.

From: Exploratory analyses of clinical outcomes from the BIIB080 phase 1b study in mild Alzheimer’s disease

Extended Data Fig. 4: Spaghetti plots of MMSE (A), CDR-SB (B), and FAQ (C) scores at each visit during the MAD and LTE periods.

CDR-SB, Clinical Dementia Rating Scale–Sum of Boxes; FAQ, Functional Activities Questionnaire; LTE, long-term extension; MAD, multiple–ascending dose; MMSE, Mini-Mental State Examination; Q12W, every 12 weeks. Data from the MAD period up to Week 100 for CDR-SB, MMSE, and FAQ, is included for the 16 participants from the early C and D cohorts (n = 16 participants in the high→high groups). Grey shading indicates the MAD period.

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