Extended Data Fig. 7: Characterization of ovarian health state of FMT cohort mice.
From: Estropausal gut microbiota transplant improves measures of ovarian function in adult mice
a, Representative images of ovarian hematoxylin-eosin stained sections. Scale bar: 50 µm. (b–e) Boxplots of (b) combined ovarian follicle counts (p value ~0.0041), (c) primordial, primary, secondary and antral follicle and corpus luteum counts per section (p values ~0.8689, ~0.5760, ~0.0889, ~0.0061 and ~0.5981, respectively), (d) serum concentrations of AMH, FSH (Multiplex assay), FSH (Ultra-sensitive assay), FSH combined and INHBA (p values ~0.0597, ~0.3176, 1, ~0.6701 and ~0.4428, respectively), and (e) weight percentage difference between day 0 and 16 of FMT regimen (p value ~0.5392). Boxplots show the median (center line), the 25th and 75th percentiles (bounds of the box), with whiskers extending to 1.5× the interquartile range (IQR). Individual datapoints are shown. Significance in nonparametric two-sided Wilcoxon rank-sum tests are reported for (c–e).
