Fig. 6: Characterization of serum metabolic profiles of FMT recipient mice.
From: Estropausal gut microbiota transplant improves measures of ovarian function in adult mice
a, Schematic diagram of the experimental setup. b, PCA plots of identified serum metabolites from two independent FMT cohorts. c, LDA projection scatter-plot displaying LDA1 scores for the FMT-YF and FMT-EF groups. d, Top 15 metabolites contributing to LDA-based separation, ranked by their positive and negative contributions to the LDA axis. e, Boxplots of 3,4-dihydroxyphenylpropionic acid (3,4-DHPPA, P value ~ 0.07923) and lactamide (P value ~ 0.09084) serum levels between FMT-YF and FMT-EF groups. Boxplots show the median (center line), the 25th and 75th percentiles (bounds of the box), with whiskers extending to 1.5× IQR. Individual datapoints are shown. Significance in nonparametric two-sided Wilcoxon rank-sum tests are reported for e.
