Extended Data Fig. 8: Gene expression trajectory clustering across organs.
From: Multimodal data analysis reveals asynchronous aging dynamics across female reproductive organs
A Gene count aging trajectories in the uterus, with Gene Ontology enrichments shown below clusters with significant enrichment. Clusters are grouped by the similarity of LOESS-smoothed trajectories (see Methods), with the thicker lines representing the average trajectory for each cluster. B Gene count aging trajectories in the vagina, with Gene Ontology enrichment displayed next to the significantly enriched cluster. Clusters are grouped by the similarity of LOESS-smoothed trajectories (see Methods), with the thicker lines representing the average trajectory for each cluster. In both A and B, Gene Ontology enrichment analysis significance was assessed using a one-sided hypergeometric test; FDR < 0.05.
