Hydrophobic Tag Degraders Overcome Endocrine-Resistant Breast Cancer by Recruiting HSP27-Mediated E3 Ligase Complex for ERα Proteasomal Degradation

Journal:

Angewandte Chemie International Edition

Published:

2026-05-26

DOI:

10.1002/anie.202525741

Affiliations:

7

Authors:

17

Go to article

Institutions	Authors	Share
Zhongnan Hospital, WHU, China	7.500000	0.44
Wuhan University (WHU), China	5.000000	0.29
Hubei Hongshan Laboratory, China	1.500000	0.09
State Key Laboratory of Biocatalysis and Enzyme Engineering, HUBU, China	1.500000	0.09
Wuhan Sports University (WHSU), China	1.000000	0.06
MOE Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, WHU, China	0.500000	0.03

Interested in Oncology and Carcinogenesis?