Allosteric zinc inhibition and interdomain regulation govern the catalytic mechanism of the E3-independent ubiquitin-conjugating enzyme hUBE2O

Journal:

Journal of Biological Chemistry

Published:

2025-12-30

DOI:

10.1016/j.jbc.2025.111122

Affiliations:

6

Authors:

5

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Institutions	Authors	Share
Guangzhou Institutes of Biomedicine and Health (GIBH), CAS, China	1.000000	0.20
Hong Kong-Guangdong Joint Laboratory on Stem Cell and Regenerative Medicine, China	1.000000	0.20
University of Chinese Academy of Sciences (UCAS), China	1.000000	0.20
Hong Kong Institute of Science and Innovation, CAS, China	1.000000	0.20
CUHK-GIBH CAS Joint Research Laboratory on Stem Cell and Regenerative Medicine, China	0.500000	0.10
State Key Laboratory of Respiratory Disease (SKLRD), China	0.500000	0.10

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