Synergistic CRISPR–Cas9 Host Engineering and Enzyme Evolution for Enantioselective Synthesis of a Vibegron Pyrrolidine Intermediate

Journal:

Organic Letters

Published:

2026-03-16

DOI:

10.1021/acs.orglett.6c00065

Affiliations:

4

Authors:

7

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Institutions	Authors	Share
Tianjin Institute of Industrial Biotechnology (TIB), CAS, China	3.666667	0.52
State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, TIB CAS, China	2.666667	0.38
University of Chinese Academy of Sciences (UCAS), China	0.666667	0.10

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