Bridged-Backbone Strategy Enables Asymmetric Synthesis of Highly Functionalized Oxabicyclo[3.3.1]nonanes with Anti-Osimertinib-Resistant NSCLC Activity

Journal:
Journal of the American Chemical Society
Published:
DOI:
10.1021/jacs.5c11520
Affiliations:
5
Authors:
15
Institutions Authors Share
State Key Laboratory of Bioactive Molecules and Druggability Assessment, JNU, China
4.500000
0.30
Guangdong-Hong Kong-Macau Joint Laboratory for Pharmacodynamic Constituents of TCM and New Drugs Research, China
4.500000
0.30
Jinan University (JNU), China
3.000000
0.20
State Key Laboratory of Respiratory Disease (SKLRD), China
2.000000
0.13
Southern University of Science and Technology (SUSTech), China
1.000000
0.07