PROTAC-Mediated Degradation of mHTT Aggregates Attenuates Neurotoxicity in Cellular and R6/2 Mouse Models of Huntington’s Disease

Journal:

Journal of the American Chemical Society

Published:

2026-02-19

DOI:

10.1021/jacs.5c14078

Affiliations:

6

Authors:

9

Go to article

Institutions	Authors	Share
Institute of Chemistry, Academia Sinica, Taiwan	5.583333	0.62
National Taiwan University (NTU), Taiwan	1.333333	0.15
Institute of Biomedical Sciences (IBMS), Academia Sinica, Taiwan	1.000000	0.11
Taiwan International Graduate Program in Chemical Biology and Molecular Biophysics (TIGP-CBMB), Taiwan	0.583333	0.06
National Chiayi University, Taiwan	0.250000	0.03
Taiwan International Graduate Program in Interdisciplinary Neuroscience (TIGP-INS), Taiwan	0.250000	0.03

Interested in Neurosciences?