Nicotine-Inspired, De Novo-Designed SARS-CoV‑2 Main Protease Inhibitors Reveal Unique Chemistry for Covalently Conjugating Both Cysteine and Histidine Residues in the Catalytic Dyad

Journal:

Journal of the American Chemical Society

Published:

2026-04-14

DOI:

10.1021/jacs.6c01119

Affiliations:

9

Authors:

19

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Institutions	Authors	Share
Texas A&M University (TAMU), United States of America (USA)	17.000000 17.000000	0.89
Lawrence Berkeley National Laboratory (LBNL), United States of America (USA)	1.000000	0.05
The University of Texas at Austin (UT Austin), United States of America (USA)	1.000000	0.05

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