Chemically modified CRISPR-Cas9 enables targeting of individual G-quadruplex and i-motif structures, revealing ligand-dependent transcriptional perturbation

Journal:

Nature Communications

Published:

2025-12-09

DOI:

10.1038/s41467-025-67074-z

Affiliations:

8

Authors:

17

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Institutions	Authors	Share
Imperial College London (ICL), United Kingdom (UK)	10.666667 10.666667	0.63
UCL, United Kingdom (UK)	2.000000	0.12
NIH National Cancer Institute (NCI), United States of America (USA)	2.000000	0.12
The Institute of Cancer Research (ICR), United Kingdom (UK)	1.000000	0.06
Ghent University (UGent), Belgium	0.500000	0.03
University of Milan (UNIMI), Italy	0.500000	0.03
The Francis Crick Institute, United Kingdom (UK)	0.333333	0.02

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