Inhibition of the cancer stem cell immune checkpoint SOAT1 suppresses regulatory T cell functions through a trans-cellular 20(S)-Hydroxycholesterol-GPR132 pathway in mice

Journal:

Nature Communications

Published:

2026-03-17

DOI:

10.1038/s41467-026-69305-3

Affiliations:

9

Authors:

13

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Institutions	Authors	Share
Zhongshan Hospital, Fudan University, China	7.900000	0.61
Fudan University, China	2.200000	0.17
Shanghai Pulmonary Hospital, China	1.000000	0.08
Kunming Institute of Zoology (KIZ), CAS, China	1.000000	0.08
Xinhua Hospital, SJTU, China	0.500000	0.04
State Key Laboratory of Genetic Engineering, Fudan University, China	0.200000	0.02
Children's Hospital, Fudan University, China	0.200000	0.02

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