A rapid imaging-based screen for induced-proximity degraders identifies a potent degrader of oncoprotein SKP2

Journal:

Nature Biotechnology

Published:

2025-09-10

DOI:

10.1038/s41587-025-02793-8

Affiliations:

17

Authors:

42

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Institutions	Authors	Share
State Key Laboratory of Cellular Stress Biology, XMU, China	10.000000 10.000000	0.24
University of Chinese Academy of Sciences (UCAS), China	7.500000	0.18
Institute of Biochemistry and Cell Biology (IBCB), SIBS CAS, China	6.666667	0.16
State Key Laboratory of RNA Innovation, Science and Engineering, SIBS CAS, China	5.166667	0.12
State Key Laboratory of Chemical Reaction Dynamics, China	3.000000	0.07
Cancer Center, WCSM/WCH SCH, China	2.000000	0.05
Interdisciplinary Research Center of Biology and Chemistry (IRCBC), China	1.500000	0.04
CAS Center for Excellence in Molecular Cell Science, SIBS CAS, China	1.000000	0.02
West China School of Medicine/West China Hospital of Sichuan University (WCSM/WCH), SCU, China	1.000000	0.02
Defand Therapeutics, China	1.000000	0.02
Yangpu Hospital, Tongji University, China	1.000000	0.02
Shanghai Institute of Materia Medica (SIMM), CAS, China	0.833333	0.02
SIMM -uOttawa Joint Research Center in Systems and Personalized Pharmacology, China	0.833333	0.02
ShanghaiTech University, China	0.500000	0.01

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