Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function

Journal:

Nature Immunology

Published:

2026-01-15

DOI:

10.1038/s41590-025-02381-7

Affiliations:

64

Authors:

86

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Institutions	Authors	Share
Imagine Institute, France	12.700000 12.700000	0.15
Garvan Institute of Medical Research, Australia	11.000000 11.000000	0.13
Laboratory of Human Genetics of Infectious Diseases (GHMI), Imagine Institute, France	5.950000	0.07
Sant'Orsola Malpighi Hospital, Italy	4.500000	0.05
The Rockefeller University, United States of America (USA)	3.333333	0.04
Institut Cochin, France	3.000000	0.03
CRUK Scotland Institute, United Kingdom (UK)	2.833333	0.03
IRCCS Meyer Children's Hospital, Italy	2.500000	0.03
Boston Children's Hospital (BCH), United States of America (USA)	2.333333	0.03
Broad Institute of MIT and Harvard, United States of America (USA)	2.333333	0.03
Dana-Farber Cancer Institute (DFCI), United States of America (USA)	2.333333	0.03
San Gerardo Hospital, Italy	2.000000	0.02
University of New South Wales (UNSW Sydney), Australia	2.000000	0.02
Toulouse University Hospital (CHU-Toulouse), France	2.000000	0.02
Hôpital Necker-Enfants Malades, France	1.833333	0.02
Science for Life Laboratory (SciLifeLab), Sweden	1.500000	0.02
San Raffaele Scientific Institute, Italy	1.500000	0.02
SJD Barcelona Children's Hospital​ for Maternal and Child Health, BMA, Spain	1.500000	0.02
University of Florence (UNIFI), Italy	1.500000	0.02
Structure Fédérative de Recherche Necker (SFR Necker), France	1.333333	0.02
Heidelberg University (Uni Heidelberg), Germany	1.000000	0.01
Children's Hospital, CHU-Toulouse, France	1.000000	0.01
Post Graduate Institute of Medical Education and Research (PGIMER), India	1.000000	0.01
Hospital Universitario Miguel Servet, Unizar, Spain	1.000000	0.01
Ghent University Hospital, Belgium	1.000000	0.01
Centre de Recherche en Cancérologie de Toulouse (CRCT), France	1.000000	0.01
Cochin Hospital, France	1.000000	0.01
Medical Laboratory of Dr. Shahrooei, Iran	1.000000	0.01
Hamad Bin Khalifa University (HBKU), Qatar	0.833333	0.01
Sidra Medical and Research Center, Qatar	0.833333	0.01
Ludwig Maximilians University of Munich (LMU), Germany	0.700000	0.01
University of Antioquia (UdeA), Colombia	0.583333	0.01
Tehran University of Medical Sciences (TUMS), Iran	0.500000	0.01
Children's Medical Center, TUMS, Iran	0.500000	0.01
University of Barcelona (UB), Spain	0.500000	0.01
The University of Sydney (USYD), Australia	0.500000	0.01
Royal Prince Alfred Hospital (RPAH), USYD, Australia	0.500000	0.01
University of Bologna (UNIBO), Italy	0.500000	0.01
Hôpitaux Universitaires Paris Ouest, France	0.500000	0.01
University Medical Center Freiburg, Germany	0.500000	0.01
Ulm University Medical Center, Germany	0.500000	0.01
Karolinska Institute (KI), Sweden	0.500000	0.01
Vita-Salute San Raffaele University (UniSR), Italy	0.500000	0.01
University of Glasgow, United Kingdom (UK)	0.500000	0.01
The Jackson Laboratory (JAX), United States of America (USA)	0.333333	0.00
Hôpital Saint-Louis, France	0.333333	0.00
Dr. von Hauner Children's Hospital, LMU, Germany	0.200000	0.00
DZKJ partner site Munich, Germany	0.200000	0.00
Howard Hughes Medical Institute (HHMI), United States of America (USA)	0.000000	0.00

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