Targeting TMED4 enhances CD8+ T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis

Journal:

Science Advances

Published:

2026-06-12

DOI:

10.1126/sciadv.aee0517

Affiliations:

10

Authors:

21

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Institutions	Authors	Share
Shanghai Tongren Hospital, SJTU, China	3.916667	0.19
Ruijin Hospital, SJTU, China	3.916667	0.19
Shanghai Institute of Immunity and Infection (SIII), CAS, China	3.916667	0.19
State Key Laboratory of Chemical Oncogenomics, China	2.500000	0.12
Zunyi Medical University (ZMU), China	2.250000	0.11
China Medical University (CMU), Taiwan	2.000000	0.10
State Key Laboratory of Systems Medicine for Cancer, SJTU, China	1.000000	0.05
Candiolo Cancer Institute (FPO-IRCCS), Italy	1.000000	0.05
Shenzhen Bay Laboratory, China	0.500000	0.02