A genome-wide in vivo CRISPR activation screen identifies BACE1 as a therapeutic vulnerability of lung cancer brain metastasis

Journal:

Science Translational Medicine

Published:

2025-07-02

DOI:

10.1126/scitranslmed.adu2459

Affiliations:

21

Authors:

40

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Institutions	Authors	Share
McMaster University, Canada	22.666667 22.666667 22.666667	0.57
Lerner Research Institute, Cleveland Clinic, United States of America (USA)	2.666667	0.07
Western University (UWO), Canada	2.500000	0.06
The Hospital for Sick Children (SickKids), U of T, Canada	2.000000	0.05
H. Lee Moffitt Cancer Center & Research Institute, United States of America (USA)	2.000000	0.05
University of Calgary (U of C), Canada	1.000000	0.03
Snyder Institute for Chronic Diseases, Canada	1.000000	0.03
Stanford Medicine, United States of America (USA)	1.000000	0.03
The Francis Crick Institute, United Kingdom (UK)	1.000000	0.03
CRUK Lung Cancer Centre of Excellence, United Kingdom (UK)	1.000000	0.03
Concordia University of Edmonton, Canada	1.000000	0.03
UCL, United Kingdom (UK)	1.000000	0.03
London Health Sciences Centre (LHSC), Canada	0.500000	0.01
Case Comprehensive Cancer Center (Case CCC), United States of America (USA)	0.333333	0.01
Center for Cancer Stem Cell Research, Cleveland Clinic, United States of America (USA)	0.333333	0.01

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