2019 Research Leaders: Leading corporate institutions

The 2019 Research Leaders are based on Nature Index data from 1 January 2018 to 31 December 2018.

Table criteria

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Position Institution Share 2017 Share 2018 Count 2018 Change in Share 2017–2018
1 Roche, Switzerland 53.08 57.49 135
8.3%
2 IBM, United States of America (USA) 47.71 40.65 112
-14.8%
3 Novartis, Switzerland 41.43 30.49 106
-26.4%
4 AstraZeneca, United Kingdom (UK) 30.13 30.10 136
-0.1%
5 Merck & Co, United States of America (USA) 35.51 28.72 68
-19.1%
6 Alphabet, United States of America (USA) 9.31 21.49 56
130.7%
7 Pfizer, United States of America (USA) 23.24 21.11 64
-9.2%
8 Earth Sciences New Zealand, New Zealand 21.08 20.45 99
-3.0%
9 Bristol-Myers Squibb, United States of America (USA) 16.34 18.59 46
13.8%
10 GSK, United Kingdom (UK) 16.67 18.04 85
8.2%
11 Amgen, United States of America (USA) 14.68 17.38 58
18.3%
12 NTT, Japan 7.11 16.56 39
132.9%
13 Samsung Group, South Korea 15.03 15.72 71
4.6%
14 Microsoft, United States of America (USA) 11.60 13.73 69
18.4%
15 Thermo Fisher Scientific, United States of America (USA) 7.62 11.66 56
53.0%
16 Dow, United States of America (USA) 10.55 10.13 32
-4.0%
17 CanSinoBIO, China 8.83 10.11 78
14.5%
18 Johnson & Johnson, United States of America (USA) 10.64 9.85 39
-7.4%
19 Toyota, Japan 8.38 9.53 25
13.7%
20 ExxonMobil, United States of America (USA) 7.82 8.60 28
9.9%
21 Regeneron Pharmaceuticals, United States of America (USA) 4.95 8.00 19
61.6%
22 SSAI, United States of America (USA) 5.88 7.95 35
35.1%
23 BASF, Germany 7.88 7.94 44
0.7%
24 Sanofi, France 5.48 7.21 33
31.5%
25 AbbVie, United States of America (USA) 8.55 7.06 23
-17.5%
26 BGI, China 6.54 6.83 32
4.5%
27 China Aerospace Science and Technology Corporation (CASC), China 4.26 6.69 44
57.2%
28 Takeda, Japan 4.98 6.46 21
29.7%
29 Bayer, Germany 3.75 6.32 43
68.7%
30 Bruker, United States of America (USA) 7.32 6.31 39
-13.8%
31 Leidos, United States of America (USA) 4.27 6.30 82
47.5%
32 Hitachi, Japan 4.82 6.23 26
29.1%
33 Jinchuan Group, China 4.09 6.03 30
47.4%
34 Lilly, United States of America (USA) 9.38 5.93 32
-36.7%
35 Boehringer Ingelheim, Germany 6.37 5.49 24
-13.9%
36 UCB, Belgium 4.16 5.32 14
28.0%
37 Toshiba, Japan 7.91 5.28 8
-33.2%
38 China National Petroleum Corporation (CNPC), China 0.70 5.09 18
627.1%
39 Eisai, Japan 4.86 4.47 19
-8.0%
40 Thales, France 4.11 4.36 37
6.0%
41 Ionis Pharmaceuticals, United States of America (USA) 3.45 4.08 21
18.1%
42 HP, United States of America (USA) 3.76 4.05 10
7.5%
43 Merck Group, Germany 3.82 3.84 24
0.5%
44 NORCE, Norway 2.57 3.68 54
43.3%
45 Intel, United States of America (USA) 2.56 3.43 21
34.1%
46 Shimadzu, Japan 1.97 3.38 14
72.0%
47 JANUS, United States of America (USA) 1.14 3.33 9
191.3%
48 Novo Nordisk, Denmark 5.86 3.33 16
-43.1%
49 Illumina, United States of America (USA) 3.21 3.22 16
0.4%
50 Shell, United Kingdom (UK) 2.88 3.22 15
11.8%
51 Agilent, United States of America (USA) 3.24 3.14 16
-3.1%
52 JEOL, Japan 2.43 3.13 24
29.2%
53 CeNTech, Germany 2.95 3.09 17
4.8%
54 China Electronics Technology Group Corporation (CETC), China 1.97 3.06 12
55.4%
55 Abbott, United States of America (USA) 0.10 3.04 6
2,904.5%
56 Sinochem Holdings, China 4.67 3.01 15
-35.5%
57 Sinopoly, China 0.49 2.90 13
493.5%
58 Shanghai Zijian Chemical Technology, China 0.43 2.83 13
553.1%
59 China Academy of Sciences Chengdu Organic Chemicals Co., Ltd., China 2.72 2.72 8
-0.2%
60 TotalEnergies, France 1.90 2.69 13
41.9%
61 New England Biolabs, United States of America (USA) 3.63 2.68 7
-26.1%
62 Synfuels China, China 1.23 2.57 15
108.3%
63 Sociedad Europea de Análisis Diferencial de Movilidad SL (SEADM), Spain N/A 2.56 4 N/A
64 D-Wave Systems, Inc., Canada N/A 2.50 4 N/A
65 SABIC, Saudi Arabia 1.76 2.46 8
39.7%
66 Waters, United States of America (USA) 3.27 2.45 9
-25.1%
67 Johnson Matthey (JM), United Kingdom (UK) 2.12 2.45 11
15.8%
68 Human Longevity, Inc., United States of America (USA) 3.74 2.43 6
-35.0%
69 Rigaku, Japan 2.48 2.37 14
-4.1%
70 Mitsubishi Chemical Holdings Corporation (MCHC), Japan 2.93 2.35 18
-19.8%
71 DuPont, United States of America (USA) 2.18 2.30 18
5.6%
72 D. E. Shaw Research, United States of America (USA) 0.08 2.30 5
2,655.4%
73 Gilead, United States of America (USA) 1.64 2.29 10
40.2%
74 HRL Laboratories LLC, United States of America (USA) 2.63 2.28 6
-13.1%
75 Xanadu, Canada 0.25 2.25 3
800.0%
76 Jacobs, United States of America (USA) 2.40 2.22 30
-7.6%
77 Corning, United States of America (USA) 0.26 2.21 6
761.0%
78 Tata Group, India 0.20 2.17 12
993.7%
79 Corteva Agriscience, United States of America (USA) N/A 2.14 3 N/A
80 South Australian Water Corporation (SA Water), Australia 2.23 2.06 6
-7.7%
81 Haldor Topsøe A/S, Denmark 2.14 2.03 7
-5.1%
82 GATS, United States of America (USA) 4.58 2.02 10
-56.0%
83 Metrohm DropSens S.L., Spain 1.00 2.00 2
100.0%
83 Piramal Enterprises Limited, India N/A 2.00 2 N/A
83 Novilytic, LLC, United States of America (USA) N/A 2.00 2 N/A
84 Otsuka Pharmaceutical, Japan 0.49 1.97 15
302.7%
85 ams-OSRAM AG, Austria 0.54 1.94 6
258.4%
86 Wellspring Biosciences, United States of America (USA) N/A 1.90 2 N/A
87 Biogen, United States of America (USA) 6.96 1.88 14
-72.9%
88 China National Tobacco Company (CNTC), China 3.29 1.88 10
-42.9%
89 GlobalFoundries, United States of America (USA) 0.63 1.84 4
191.4%
90 NorthWest Research Associates (NWRA), United States of America (USA) 4.98 1.83 21
-63.1%
91 Sinopec, China 1.70 1.83 27
7.8%
92 Peptide Institute, Inc., Japan 0.88 1.83 2
109.5%
93 Techint Group, Italy 1.51 1.82 14
20.7%
94 Saudi Aramco, Saudi Arabia 1.72 1.78 7
3.6%
95 CSSC, China 1.89 1.77 105
-6.2%
96 Procter & Gamble (P&G), United States of America (USA) 0.58 1.77 8
207.4%
97 PacBio, United States of America (USA) 1.08 1.75 12
62.6%
98 ToolGen, Inc., South Korea 0.62 1.74 3
181.9%
99 KWR Water Research Institute, Netherlands 2.62 1.74 11
-33.5%
100 Lockheed Martin, United States of America (USA) 2.16 1.73 19
-20.0%
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Footnote

Each year, the Nature Index publishes tables based on counts of high-quality research outputs in the previous calendar year. Users please note:

  1. The data behind the tables are based on a relatively small proportion of total research papers, they cover the natural sciences only and outputs are non-normalized (that is, they don’t reflect the size of the country or institution, or its overall research output).
  2. The Nature Index is one indicator of institutional research performance. The metrics of Count and Share used to order Nature Index listings are based on an institution’s or country/territory’s publication output in 82 high-quality natural science publications. The publications were chosen by an independent group of researchers. The list is reviewed periodically and journals may be removed or added.
  3. Nature Index recognizes that many other factors must be taken into account when considering research quality and institutional performance; Nature Index metrics alone should not be used to assess institutions or individuals.
  4. Nature Index data and methods are transparent and the data in the above table is published under a creative commons licence at nature.com/nature-index/.
  5. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

The Nature Index database undergoes regular updating, corrections, adjustment of institutional hierarchies, and removal of retracted papers and thus the live website can differ from the research leaders tables.

Research Leaders tables from previous years are also updated annually to reflect any changes to the database. This means rankings and metrics may differ from the table when first released.


Numerical information only (in the tables above) is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International.