2022 Research Leaders: Leading corporate institutions

The 2022 Research Leaders are based on Nature Index data from 1 January 2021 to 31 December 2021.

Table criteria

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Position Institution Share 2020 Share 2021 Count 2021 Change in Share 2020–2021
1 Roche, Switzerland 58.89 45.32 133
-23.0%
2 AstraZeneca, United Kingdom (UK) 27.54 35.24 139
27.9%
3 IBM, United States of America (USA) 30.15 34.82 96
15.5%
4 Alphabet, United States of America (USA) 26.61 32.10 79
20.6%
5 Merck & Co, United States of America (USA) 32.35 26.20 66
-19.0%
6 Novartis, Switzerland 24.37 21.34 96
-12.4%
7 Pfizer, United States of America (USA) 17.11 20.25 64
18.4%
8 Bristol-Myers Squibb, United States of America (USA) 18.81 15.87 42
-15.6%
9 Earth Sciences New Zealand, New Zealand 16.61 14.69 83
-11.5%
10 Samsung Group, South Korea 15.09 13.77 70
-8.8%
11 CanSinoBIO, China 9.58 13.12 82
37.0%
12 Thermo Fisher Scientific, United States of America (USA) 9.64 12.79 58
32.7%
13 Regeneron Pharmaceuticals, United States of America (USA) 13.98 12.51 32
-10.5%
14 GSK, United Kingdom (UK) 20.38 12.08 55
-40.7%
15 Toyota, Japan 15.39 11.93 25
-22.5%
16 NTT, Japan 12.59 11.78 29
-6.4%
17 Johnson & Johnson, United States of America (USA) 14.88 11.69 55
-21.4%
18 Amgen, United States of America (USA) 12.10 11.42 35
-5.6%
19 Takeda, Japan 3.27 10.68 28
226.3%
20 AbbVie, United States of America (USA) 6.19 10.18 27
64.4%
21 ExxonMobil, United States of America (USA) 8.77 10.13 28
15.5%
22 Bruker, United States of America (USA) 11.98 10.11 53
-15.6%
23 Microsoft, United States of America (USA) 11.18 10.02 56
-10.4%
24 BGI, China 7.57 10.00 51
32.1%
25 Sanofi, France 8.66 8.93 43
3.1%
26 Dow, United States of America (USA) 6.11 7.78 36
27.4%
27 Leidos, United States of America (USA) 7.63 7.21 85
-5.5%
28 Boehringer Ingelheim, Germany 5.74 6.68 30
16.3%
29 New England Biolabs, United States of America (USA) 1.51 6.53 11
333.2%
30 Jinchuan Group, China 2.47 6.48 23
162.5%
31 BASF, Germany 8.45 6.46 40
-23.5%
32 Vir Biotechnology, United States of America (USA) 3.11 6.17 19
98.4%
33 Waters, United States of America (USA) 4.75 5.84 12
23.0%
34 China Aerospace Science and Technology Corporation (CASC), China 8.25 5.69 39
-31.0%
35 Ionis Pharmaceuticals, United States of America (USA) 4.60 5.65 26
22.7%
36 Moderna, United States of America (USA) 2.86 5.60 14
96.1%
37 SSAI, United States of America (USA) 3.26 5.35 37
64.2%
38 Novo Nordisk, Denmark 6.88 5.21 27
-24.3%
39 Bayer, Germany 6.31 5.13 26
-18.7%
40 Lilly, United States of America (USA) 7.38 5.04 32
-31.7%
41 Gilead, United States of America (USA) 4.58 4.93 13
7.5%
42 Toshiba, Japan 1.50 4.57 8
204.8%
43 China National Petroleum Corporation (CNPC), China 4.42 4.53 24
2.4%
44 Biogen, United States of America (USA) 5.23 4.44 19
-15.1%
45 KWR Water Research Institute, Netherlands 2.81 4.34 17
54.5%
46 Intel, United States of America (USA) 3.41 4.17 20
22.2%
47 General Atomics, United States of America (USA) 2.12 4.11 15
94.1%
48 Thales, France 3.51 4.08 53
16.2%
49 UCB, Belgium 3.43 4.06 16
18.2%
50 Sinochem Holdings, China 6.67 3.94 22
-41.0%
51 SABIC, Saudi Arabia 1.30 3.78 14
189.9%
52 China National Tobacco Company (CNTC), China 3.09 3.64 12
17.7%
53 Merck Group, Germany 1.06 3.59 18
239.3%
54 Xanadu, Canada 1.65 3.56 4
115.5%
55 China Electronics Technology Group Corporation (CETC), China 4.48 3.27 16
-27.0%
56 Hitachi, Japan 8.52 3.24 17
-61.9%
57 Panasonic, Japan 2.88 3.11 7
8.0%
58 BioNTech, Germany 3.56 3.09 12
-13.3%
59 Sinopec, China 1.89 3.08 28
63.2%
60 Eisai, Japan 0.23 3.04 8
1,225.6%
61 Corning, United States of America (USA) 2.04 2.98 8
46.3%
62 LG, South Korea 2.76 2.95 11
6.9%
63 CSSC, China 2.00 2.94 144
46.8%
64 Shell, United Kingdom (UK) 4.14 2.87 12
-30.6%
65 Bioqual, United States of America (USA) 1.72 2.85 18
65.6%
66 NORCE, Norway 4.30 2.66 45
-38.0%
67 TotalEnergies, France 4.08 2.60 15
-36.2%
68 AGC Inc., Japan N/A 2.57 6 N/A
69 CeNTech, Germany 2.70 2.52 13
-6.7%
70 Techint Group, Italy 2.30 2.51 22
9.3%
71 Hunan Changling Petrochemical Technology Development Co., Ltd., China 0.70 2.50 5
258.2%
72 Danaher, United States of America (USA) 3.45 2.47 15
-28.3%
73 China Communications Construction Company (CCCC), China 3.28 2.42 19
-26.2%
74 JANUS, United States of America (USA) 0.83 2.42 11
190.2%
75 RTX, United States of America (USA) 2.33 2.41 24
3.5%
76 EpiCypher, United States of America (USA) 0.29 2.28 7
679.4%
77 NorthWest Research Associates (NWRA), United States of America (USA) 3.06 2.27 27
-25.8%
78 Unilever, United Kingdom (UK) 2.27 2.24 10
-1.3%
79 Saudi Aramco, Saudi Arabia 1.85 2.22 12
19.8%
80 Abbott, United States of America (USA) 0.41 2.18 9
428.2%
81 HRL Laboratories LLC, United States of America (USA) 1.85 2.17 4
17.2%
82 TDK, Japan 0.83 2.13 5
158.4%
83 Adroit Materials, Inc., United States of America (USA) 2.17 2.09 7
-3.7%
84 Meta, United States of America (USA) 2.09 2.07 7
-1.0%
85 Rigaku, Japan 2.47 2.07 15
-16.3%
86 NaMLab, Germany N/A 2.00 5 N/A
87 Nokia, Finland 1.48 1.98 11
33.7%
88 Johnson Matthey (JM), United Kingdom (UK) 1.73 1.94 11
11.9%
89 JEOL, Japan 1.60 1.92 17
20.4%
90 Ford, United States of America (USA) 0.50 1.90 5
279.0%
91 Shimadzu, Japan 3.20 1.89 8
-41.0%
92 Synfuels China, China 0.82 1.83 13
123.7%
93 10x Genomics, United States of America (USA) 1.06 1.81 11
71.5%
94 Bosch, Germany 0.20 1.80 7
810.7%
95 Honeywell International, Inc., United States of America (USA) 1.81 1.80 6
-0.8%
96 Corteva Agriscience, United States of America (USA) 2.42 1.79 7
-26.1%
97 Western Digital, United States of America (USA) 1.43 1.78 6
24.9%
98 Mitsubishi Chemical Holdings Corporation (MCHC), Japan 1.48 1.73 13
16.6%
99 Loki Incorporated, United States of America (USA) 0.88 1.71 2
95.2%
100 Otsuka Pharmaceutical, Japan 1.38 1.70 8
22.5%
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Footnote

Each year, the Nature Index publishes tables based on counts of high-quality research outputs in the previous calendar year. Users please note:

  1. The data behind the tables are based on a relatively small proportion of total research papers, they cover the natural sciences only and outputs are non-normalized (that is, they don’t reflect the size of the country or institution, or its overall research output).
  2. The Nature Index is one indicator of institutional research performance. The metrics of Count and Share used to order Nature Index listings are based on an institution’s or country/territory’s publication output in 82 high-quality natural science publications. The publications were chosen by an independent group of researchers. The list is reviewed periodically and journals may be removed or added.
  3. Nature Index recognizes that many other factors must be taken into account when considering research quality and institutional performance; Nature Index metrics alone should not be used to assess institutions or individuals.
  4. Nature Index data and methods are transparent and the data in the above table is published under a creative commons licence at nature.com/nature-index/.
  5. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

The Nature Index database undergoes regular updating, corrections, adjustment of institutional hierarchies, and removal of retracted papers and thus the live website can differ from the research leaders tables.

Research Leaders tables from previous years are also updated annually to reflect any changes to the database. This means rankings and metrics may differ from the table when first released.


Numerical information only (in the tables above) is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International.