Agricultural Biotechnology articles for China

Time frame: 1 July 2025 - 30 June 2026

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Count: 286

Article ‘Count’ for Agricultural Biotechnology.

Journal Count Share
5 4.64
Ultrasensitive Wash-Free Homogeneous CRISPR Assay Using Spatial Proximity Chemiluminescence Reporter 1.00
Upconversion Nanoparticles Expand the Photosynthetically Active Spectrum of Microalgae into the Near-Infrared for CO2 Biofixation 1.00
Artificial Intelligence-Integrated Overcoupled Resonator for Multifunctional Pesticide Spectral Classification and Quantification 0.71
Disrupting Biofilm Tolerance by Ionic Microbubble-Mediated Copper Ion Surge for Infection Clearance 0.92
Split DNA Tetrahedron-Mediated Spatiotemporal-Hierarchy CRISPR Cascade Integrated with Au@Pt Nanolabels and Artificial Intelligence for a Cervical Cancer MicroRNA Bioassay 1.00
1 0.29
An optimised lipid nanoparticle platform enables efficient CRISPR/Cas9 genome editing in hard-to-transfect cells 0.29
6 4.66
From Algal Threat to Fe/N-Rich Single-Atom Catalyst: Engineering Iron-Accumulating Algae for High-Performance Fenton-Like Chemistry and Lifecycle Sustainability 0.88
Light‐Carbon Double Transfer Membrane for Carbon Fixation in Microalgae 0.88
Spatially Separated Dual‐Probiotic Hydrogel Enables Synergistic Infection Control and Tissue Healing 0.90
Nanopuncturing‐Enabled Efficient Gene Editing for Isogenic Human iPSC‐Derived Organoid Engineering 0.92
Engineered Microalgae‐Material Biohybrid Enhances Carbon‐Negative Hydrogen Production Under Emerging Contaminant Stress 1.00
Dynamic Real-Time Monitoring of Microalgal Photosynthesis Using Droplet Triboelectric Nanogenerators 0.09
2 2.00
Accelerated CRISPR/Cas12a-Based Point-of-Care Diagnostics Through Critical Coupling Distance Control 1.00
Janus Nanohybrids Enable Superflash Warming and High‐Affinity Ice Confinement for Cross‐Scale Cryopreservation 1.00
41 40.39
Generalized Biosensing and Signaling Reprogramming Using Circular RNA-Protein Circuit-Mediated Cargo Release 1.00
Permeable Hydrogel Microreactors for On-Chip Analysis of Diatom Growth Dynamics at Single-Cell Resolution 1.00
Covalent Photo-Aptamer Tagging (CPAT) for Single-Cell Multiplexing and Chemical Transcriptomic Screens 1.00
Guide DNA Conformation Change-Triggered Activation of Clostridium butyricum Argonautes for Biosensing 0.80
Multiplexed and Ultrasensitive Pathogens Detection with an Orthogonal Argonaute Circuit Based on Encoded Microsphere Microscopic Imaging 1.00
Cell Wall-Anchored MoOx@CuPc Nanoprobes Decode Organ-Level Metabolic Trade-Offs in Halophytes under Salt Stress 0.88
Dual Mechanisms of crRNA 3′-Extension-Mediated Cas12a Attenuation Enable Programmable One-Pot CRISPR Diagnostics 1.00
Re-Engineering CRISPR-Cas12a into a Multimodal Biosensing Platform with Programmable Precursor crRNA 1.00
An Argonaute-Based Assay for Synchronous Quantification of Deaminase Catalytic Activity toward Cytidine and 5-Methylcytidine Substrates 1.00
A Programmable Y-Shaped Catalytic Hairpin Assembly Amplification Enabling Ultrasensitive Fluorescent Analysis of Circular RNAs in Living Cells 1.00
CRISPR/dCas9-Assisted On-Bead Multiplex Detection (BeadPlex2) for Genetically Modified Crops 1.00
Enhanced SNV Detection of HLA-B*15:02TA by Integrating Blocking RPA and Inhibiting CRISPR-Cas12a 1.00
Conformationally Regulated CRISPR/Cas12a Activation Enabled by a Programmable DNA Dumbbell for Electrochemical SNP Genotyping 1.00
Stem-Engineered Aptamers with Enhanced Stability and Affinity for Tumor-Targeted Imaging 1.00
Antibody-Free and Rapid Profiling of Transcription Factor Binding Sites by Aptamer-Guided Chromatin Cleavage and Sequencing (AptaChC-Seq) 1.00
EXAGO: An Argonaute-Based Primer-Free Exponential Amplification Strategy for Ultrasensitive Zero-Background Detection of Point Mutation 1.00
Quantitative Approach for Simultaneous In Situ Profiling of Lignin, Cellulose, and Hemicellulose Using Confocal Raman Microscopy 1.00
Scaffold-Proximal DNA Extensions Enhance Cas12a Trans-cleavage for Direct and Broad-Scope Nucleic Acid Detection 1.00
Integration of Demethylation-Switchable Deoxyribozyme with Controllable Self-Assembly of Branched DNA Nanostructures Enables In Situ Monitoring of FTO Demethylation in Living Cells 1.00
An Asymmetric Stem-Loop Translator Enhances Specificity of One-Pot Isothermal CRISPR/Cas12a Assay 1.00
Deoxyribonucleic Acid Looped-Ag Nanocluster-Based Fluorescent Sensor for Accurate and Sensitive Circular Ribonucleic Acid Analysis via Dual Catalytically Deactivated Cas13a/crRNA Recognition-Mediated Proximity Ligation 1.00
Single-Tube Dual-Gene Detection of Methicillin-Resistant Staphylococcus aureus via Selective Trans-Cleavage Preferences of Cas9 and Cas12a 0.86
DNA Flap-Controlled CRISPR/Cas12a Trans-Cleavage Enables Mix-and-Read FEN1 Activity Detection 1.00
Plug-and-Play Photo-Initiated CRISPR–Cas12a One-Pot Nucleic Acid Detection via Universal Repeat RNA Acylation Strategy 1.00
A Universal Light-Activated CRISPR-RNA Based on Split Direct Repeat for One-Pot Cas12a Nucleic Acid Detection 1.00
Proximity-Inducible CRISPR/Cas12a Activity by Scaffold RNA Assembly for Sensing Applications 1.00
Affinity-Driven Two-Step Immobilization of Endogenous Natural GABAA Receptor to Quantify Drug–Protein Analysis with Enhanced Sensitivity and Accuracy 1.00
Guanine-Quadruplex-Engineered crRNA Enables Light-Activated CRISPR/Cas12a System for Robust One-Pot Viral Assay 1.00
Breaking the PAM Restriction: A Universal Double Stranded DNA Detection Method Based on the Sticky End-Mediated CRISPR/Cas12a Coupled RPA and Its Application to KRAS G12C Single Base Mutations 1.00
A Chimeric Photo-Controllable CRISPR/Cas12a System for Universal and Fast Diagnostics 0.86
Fabricating Four-Element Doped Carbon Dots-Based Fluorescent Ratiometric Reporter Platform for CRISPR/Cas-Driven Precise Sensing of Nucleic Acids 1.00
Metal-Tannic Acid Nanospheres Empowering DNA Nanoarchitectures for Multimodal Detection of Low-Abundance Pesticide-Resistance Genes 1.00
CRISPR/Cas13a trans-Cleavage-Driven Programmable Autonomous Synthesis of a Functional G-Quadruplex for Ultrasensitive Detection of Circular RNAs with an Improved Signal-to-Background Ratio 1.00
5′-End Engineering of CRISPR/Cas12a Activators: A Versatile Platform for Multiple Biomarker Analysis and Clinical Cancer Tissue Identification 1.00
Discrimination of Microalgal Cellular Metabolic Heterogeneity and sup13/supC Metabolic Flux Analysis via Micro Label-Free Mass Cytometry 1.00
Lanthanide Metal–Organic Framework-Integrated CRISPR-Cas Technology for Amplification-free Gene Mutation Assay 1.00
CONVERT: Dynamic crRNA Reconfiguration for Universal One-Pot CRISPR/Cas12a-Based Nucleic Acid Detection 1.00
Split crRNA-Mediated Regulation of CRISPR-Cas12a Enables Construction of Biochemical Circuits for Sensitive Molecular Diagnostics 1.00
Combining the NanaPPI Toolbox and AI-Driven Virtual Inhibitor Screening for the p53-MDM2 Interaction 1.00
Breakthrough in LbCas12a Chemical Inhibitor Screening: The Firefly Probe and Its Application in Dual-Mode Biosensors 1.00
SPARC: An Orthogonal Cas12a/Cas13a Dual-Channel CRISPR Platform for Reliable SNV Identification and Mutation Confirmation 1.00
6 5.75
In Situ Amplified Mutational mRNA Imaging Using a Spatially Confined CRISPR Nanoplatform 1.00
Near‐Infrared Light‐Activated Circular Oligonucleotides for Spatiotemporal Control of Gene Silencing in Mice 1.00
Bioinformatics‐Driven Design of Peptides for Membrane Stabilization During Cryopreservation 1.00
Allosteric Activation of Cas12a via PAM Topological Engineering for Direct and Rapid Detection of Nucleases 1.00
Imaging‐Based High‐Content Screening with Clickable Probes Identifies XPB Inhibitors 1.00
Light‐Triggered CRISPR/Cas12a for Genomic Editing and Tumor Regression 0.75
1 1.00
Advanced technology and applications of small-scale, modular, and distributed biomass direct air capture systems 1.00
2 2.00
TENT5A Maintains MYC mRNA Stability to Enhance Osteosarcoma Stemness 1.00
Lactobacillus johnsonii Synthesizes Chenodeoxycholic Acid to Reduce Susceptibility to High-Fat Diet–Induced Colorectal Cancer 1.00
7 6.88
Tuning the sensitivity of mechanosensory receptors through histidine scanning 0.88
AAVLINK: A potent DNA-recombination method for large cargo delivery in gene therapy 1.00
Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons 1.00
Iterative recombinase technologies for efficient and precise genome engineering across kilobase to megabase scales 1.00
Identification and application of cell-type-specific enhancers for the macaque brain 1.00
Machine-learning-assisted universal protein activation in living mice 1.00
Advancing protein evolution with inverse folding models integrating structural and evolutionary constraints 1.00
1 1.00
Microbial phosphoketolase promotes histone lactylation to improve anti-TNF therapy efficacy in inflammatory bowel disease 1.00
1 0.95
Minimizing far-extending chromatin perturbation in genome editing preserves stem cell identity 0.95
6 6.00
Sequence-independent optical regulation of CRISPR/Cas editing using star-shaped crRNA dendrimers 1.00
A label-free orthogonal dual-channel CRISPR-Cas platform for simultaneous detection of Mycobacterium tuberculosis and respiratory syncytial virus 1.00
A sticky end-driven PAM-free RPA-CRISPR/Cas12a dual amplification system for ultrasensitive detection of KRAS G12C 1.00
Integration of CRISPR/Cas12a and Cas13a in one pot for ratiometric calibration of single-nucleotide variations 1.00
CRISPR-Cas13a-based dual-channel AND-logic gated biosensor for the simultaneous assay of APE1 and miRNA-224 1.00
Enzyme inhibition-enabled CRISPR/Cas12a biosensing system for heparin-related non-nucleic acid biomarkers 1.00
3 2.83
cShot: spatial dynamic imaging of cell cycle-dependent miRNA heterogeneity using dynamic DNA patterns 1.00
Spatiotemporally regulated mitochondrial genome editing via enzyme and NIR-activated CRISPR/Cas9 nanoplatform 0.83
THRUST: translesion synthesis-driven hierarchical regulation using a template-activator construct for Cas12a activity 1.00
1 0.21
Mitigating xenogeneic barriers to chimerism through Cas13-induced host attenuation 0.21
6 5.36
Prediction of nitrogen product distribution in algal pyrolysis bio-oil driven by machine learning 1.00
Synergistic coupling of microalgae and corn cob residue biochar for enhanced lipid production and heavy metal removal from waste leachate and corn cob hydrolysate 0.86
Multiphysics Synergy Analysis of Light, CO2 Mass Transfer and Fluid Dynamics in Microalgae Photobioreactors 1.00
Comparative techno-economic and life cycle assessment of microalgae-based CO2 capture technologies for coal-fired power plants under different carbon supply modes 1.00
Transforming sludge-containing urban wastewater to clean energy and biochemicals via an algae-based carbon-neutral pyrolytic pathway 0.50
New insights into efficient lipid production and decolorization of Congo red by microalgae under anaerobic environment: Performance and degradation mechanisms 1.00
2 2.00
Dynamic extracellular polymeric substance component succession primes cyanobacterial metabolism for distinct bloom stages 1.00
Tolerance strategy of Chlorella sorokiniana to combined antibiotic stress revealed by transcriptomic analysis 1.00
12 11.90
Multi-Batch Treatment of Swine Slaughterhouse Wastewater by Microalgal–Fungal Consortium System: Stability and Effects on Dissolved Organic Matter 1.00
Performance and microbial community dynamics of an internal circulating photogranular membrane bioreactor for synthetic mariculture wastewater treatment under different hydraulic retention times 1.00
Process-Level Design of Engineered Microalgal-Bacterial Systems for Carbon-Efficient Nitrogen Removal from Low C/N Wastewater: Carbon/Electron Redistribution Revealed by Metabolic Network Analysis 1.00
A loofah-based microalgae-bacteria symbiosis drives efficient nutrient removal from low-C/N wastewater: high biomass characterization and mechanism insights 1.00
Removal of trace 17α-ethinylestradiol by microalgal-bacterial granular sludge: The overlooked role of extracellular photosensitization 1.00
Resource utilization and microbial community evolution in anaerobic digestion effluent containing heavy metal Zn via eco-remediation technology based on a PBR algal-bacterial symbiosis system 1.00
Microalgae-fungi co-cultivation for swine wastewater treatment: Insights into EPS-mediated aggregation mechanism 1.00
Unveiling the algicidal effects and compounds of a newly isolated algicidal Enterococcus sp. JL7 1.00
Phosphate-Iron Modified Enteromorpha Prolifera Hydrochar Enhances Dry Anaerobic Digestion of Food Waste: Synergistic Mechanisms of Electron Transfer Network, Microbial Consortia Remodeling, and Metagenomic Insights 0.90
Synergistic modulation of sludge hydrolysate-borne bacteria on glycogen accumulation and carbon fixation mechanisms in microalgae 1.00
Nitrate modulates high CO2-alters carbon partitioning in Gracilariopsis lemaneiformis: Trade-offs between particulate and dissolved organic carbon sequestration 1.00
New Insights into Fungi-Mediated Flocculation of Chlorella vulgaris: A Transcriptomics - Metabolomics Integration from Biosynthesis to Mechanism 1.00
6 6.00
Elevated N/P Ratios Enhance Arsenic Bioaccumulation and Biotransformation in Marine Microalgae 1.00
Enhanced Antibiotic Dissipation in Swine Wastewater Facilitated by Heavy Metals through a Transcriptionally Upregulated Microalgal Metallohydrolase 1.00
Photosystem-Driven Resilience of Green Microalga Tetraselmis chuii toward Acute Nonylphenol Stress 1.00
Revealing Single-Cell Heterogeneity of Labile Cu(I) Accumulation and Metabolism in Microalgae by Image-Enabled Flow Cytometry 1.00
Microbially Driven Organic Carbon Degradation and Nutrient Cycling during Macroalgal Decomposition 1.00
Redox Control of Copper Biotransformation and Its Toxicity Cascades in Microalgae 1.00
1 1.00
Restoring the potency of neutralizing antibody via guided hypermutation with hyper-antibody editor 1.00
1 1.00
Experimental investigation of environmental controls on biological cadmium isotope fractionation during phytoplankton uptake 1.00
2 0.99
Deciphering resistance mechanisms to auxin-inducible protein degradation in mammalian cells 0.06
A genetic manipulation tool based on the GP35 recombinase for targeted gene editing in mycoplasmas of ruminants 0.93
1 1.00
Stage- and tissue-specific gene editing using 4-OHT–inducible Cas9 in whole organism 1.00
16 15.74
Energy yield and water resource utilization in Chlorella pyrenoidosa under saline-alkali stress: An integrated physiological, ionomic, and transcriptomic approach 1.00
Phycosphere microbial assembly reinforces microalgae-driven soil organic carbon sequestration and methane mitigation in black soil paddies 1.00
Biomimetic strategy enhanced microalgal CO2 fixation via dual synergies in photosynthetic electron flow 0.89
Prediction and optimization of light transmission to enhance microalgae growth in built-in light sources photobioreactor for efficient CO2 fixation 1.00
Fe-doped quantum dots boost synergistic dual-cycle carbon fixation for value-added products synthesis in anoxygenic photoheterotrophs: an innovative strategy toward high-efficiency wastewater valorization with net carbon reduction 1.00
Development and application of a CRISPR/Cas9n system for deleting multiple secretion-related protein genes in Bacillus amyloliquefaciens to facilitate industrial enzymes clean production 1.00
Process design and techno-economic evaluation of hydrogen production from microalgae conversion in molten salts 1.00
Coordinating sulfamethoxazole removal and fouling control through species–ratio configurations in membrane microalgal–bacterial coupling systems 1.00
Utilizing food waste hydrolysate for enhanced microalgae protein production: a step towards circular economy 1.00
Screening and characterization of marine cyanobacteria for dairy farm wastewater treatment: Nodosilinea sp. E11 as a promising candidate for phycoremediation 1.00
Efficient biosorption of molybdenum (VI) using Chlorella pyrenoidosa biomass: Mechanistic insights and sustainable application in water remediation 1.00
Mechanisms of naphthalene biodegradation in microalgal-bacterial co-culture systems: role of photosynthesis, antioxidant and extracellular polymeric substances 1.00
Two-stage cultivation using noodle soup waste water for the sustainable production of microalgal biomass and biodiesel 0.93
Efficient amplification of marine dark carbon fixation at the bioreactor scale: Bottlenecks and regulating strategies 1.00
Phototrophic microalgae-driven comprehensive remediation of arsenic and cadmium: A novel iron mineralization pathway enabling arsenic immobilization 0.92
Techno-economic analysis of Spirulina biomass production in the floating photobioreactors for fishmeal replacements 1.00
1 0.07
Single-dose genome editing therapy rescues auditory and vestibular functions in adult mice with DFNA41 deafness 0.07
3 3.00
A Computationally Optimized Ribonucleic Acid Circularization Strategy without Byproducts 1.00
Creating a Modular Activatable CRISPR–Cas12a System by Engineering crRNA Scaffold with a Steric Hindrance Effector 1.00
Photocontrolled Programmable Enzymatic Cascade for Robust CRISPR Diagnostics 1.00
6 5.82
IS110 transposon utilizes two mechanistically distinct RNA-guided transposition pathways 1.00
Rapid customization of base editors via machine learning-powered combinatorial mutagenesis 1.00
Molecular basis for dual-spacer-guided target cleavage by the TIGR-TasH system 1.00
Structural basis for Cas9-directed spacer acquisition in type II-A CRISPR-Cas systems 0.82
Engineered hypercompact Fanzor-ωRNA system with enhanced genome editing activity 1.00
Structural insights into DdCBE in action enable high-precision mitochondrial DNA editing 1.00
2 2.00
Near-Infrared Light-Inducible CRISPR-Cas12a/Tetrahedral DNA Nanosystem for Spatiotemporal Control of mtDNA Mutation Imaging and Gene Therapy 1.00
A Nanoimprinted Photothermal Chip for On-Demand Spatiotemporal Activation of CRISPR/Cas9 Gene Editing 1.00
4 3.63
Teosinte alleles enhance nitrogen assimilation and seed protein in maize 0.96
Quadruple pegRNA enables programmable and efficient large genomic insertion 1.00
Synthetic circuits for cell ratio control 0.67
In vivo base editing of Chd3 rescues behavioural abnormalities in mice 1.00
7 6.93
Multiplexed, precise genome engineering in monocots with twin prime editing systems 1.00
Programmable, multiplexed and orthogonal gene control in bacteria with attenuated Cas13d systems 1.00
DNA-guided CRISPR–Cas12a effectors for programmable RNA recognition and cleavage 1.00
Single-round evolution of RNA aptamers with GRAPE-LM 1.00
Single-strand deaminase-assisted editing for functional RNA manipulation 0.93
CRISPR live-cell imaging reveals chromatin dynamics and enhancer interactions at multiple non-repetitive loci 1.00
Design of optimized epigenetic regulators for durable gene silencing with application to PCSK9 in nonhuman primates 1.00
2 2.00
A gasdermin-based life–death evolution system for reprogramming protease specificity 1.00
Efficient and precise inversion of genomic DNA from large to chromosomal scale 1.00
1 1.00
Photocatalytic labelling-enabled subcellular-resolved RNA profiling and synchronous multi-omics investigation 1.00
64 58.10
Development of efficient genetic toolkits and heterologous chassis for bioprospecting of myxobacteria 1.00
Probing the limits of genetic recoding using multi-omics-guided evolution 0.05
Moderate-temperature DNA cleavage activity of TtAgo activated by dCTP/TthSSB for one-step isothermal microRNAs detection 0.89
Deep learning–guided engineering of SpuFz1 and rational miniaturization of ωRNA enables efficient genome editing 1.00
Guide RNA reprogramming facilitates minimized tracrRNA-dependent off-target and versatile CRISPR/Cas9 engineering 1.00
High-throughput Raman-activated cell sorting of microalgal genome-wide edited library revealed a regulatory pathway for carotenoid synthesis 0.85
Optimization of IS621 recombinase/bridge RNA-directed recombination for precise insertion of large DNA fragments in human cells 1.00
Structural basis for dual mechanism of Cas2/3 nuclease inhibition by anti-CRISPR protein AcrIF19 1.00
Engineered dCas12f1-SAM enables robust transcriptional activation and gain-of-function screening in primary human cells 1.00
Photoactivatable CRISPR/Cas13d via upconversion nanoparticles for deep tissue RNA engineering and orthopedic therapy 0.96
Sensitive monitoring of enhancer and noncoding RNA transcription via ribozyme-assisted RNA editing 1.00
Molecular basis of target RNA cleavage by Cas13 1.00
Activation mechanism and integrated one-pot assay of chiral-like cRNA-enhanced CRISPR/Cas12a systems 1.00
Skeletal editing via multi-step engineering of a modular polyketide synthase 0.08
Structural insights into C-terminus-mediated RNA target cleavage by a mesophilic prokaryotic argonaute 1.00
Miniature and versatile genome regulation TnpB-ωRNA toolkits facilitate cancer immunotherapy 0.95
Engineered microbial hydrogels with confined architecture and binary microbes for efficient hydrogen production 1.00
Target-stabilized base editors enable robust high-fidelity RNA editing 1.00
Engineered Un1Cas12f1 for multiplex genome editing with enhanced activity and targeting scope 1.00
Engineered bacterial therapy suppresses Enterohemorrhagic through metabolic competition and virulence silencing 1.00
Click-based determination of accumulation of molecules in Escherichia coli 0.14
Engineering the MmeFz2-ωRNA system for efficient genome editing through an integrated computational-experimental framework 1.00
Af-CUTTag: a sensitive and antibody-free chromatin profiling method using genetically encoded tags and high-affinity binders fused to Tn5 1.00
Coiled-coil heterodimer-mediated split base editing systems enable flexible and robust nucleotide substitutions 1.00
Identification of thermotolerant non-canonical PAMs for robust one-pot CRISPR-Cas12a detection 1.00
A compact and inducible dCas12f-based CRISPRa platform for programmable in vivo gene activation 1.00
In vivo chemogenetic RNA editing of macrophages by bioengineered viruses for sepsis treatment 1.00
Interactions with bacteria shape diatom adaptation to carbon concentration changes 1.00
Computational design of allulose-responsive biosensor toolbox for auto-inducible protein expression and CRISPRi mediated dynamic metabolic regulation 1.00
A Plug-in system for reprogramming the editing patterns of base editors 1.00
Manganese-engineered Lactobacillus Reuteri with enhanced antitumor and immunomodulatory activities for colorectal cancer prevention and treatment 1.00
Anti-CRISPR protein AcrIIA5 can enhance the activity and security of prime editing 1.00
Protein-nucleic acid language model-assisted design of precise and compact adenine base editor 0.77
Efficient high-precision transgene knock-in by Recombinases (Redα/β)-enhanced DNA integration-CRISPR-Cas9 (RED-CRISPR) 1.00
Architecture and mechanism of a dual-enzyme retron system in prokaryotic immunity 1.00
Versatile molecular tools enabling customizable DNA methylation editing in Arabidopsis 0.81
CRISPR-free RNA base editing mediated PTC-readthrough restores hearing in mice with nonsense mutation 1.00
A flanking-nicks prime editor (FLICK-PE) system to boost prime editing in dicots 1.00
Programmable targeted RNA degradation via dCas13d-directed chaperone-mediated autophagy (dCasCMA) 1.00
Engineering a CRISPR-associated IscB system for developing miniature genome-editing tools in human cells and mouse embryos 1.00
Deep generative optimization of mRNA codon sequences for enhanced mRNA translation and therapeutic efficacy 1.00
Deep learning models simultaneously trained on multiple datasets improve base-editing activity prediction 0.10
Effective in vivo RNA base editing via engineered cytidine deaminase APOBECs fused with PUF proteins 0.82
A temperature-sensitive CRISPR-Cas12a system for sterile insect technique 0.20
Noncanonical target-strand cytosine base editing via engineered Un1Cas12f1 platform 1.00
Structure-function relationship of the GH168 fucanase reveals an unusual enzyme recognition mechanism for sulfated polysaccharide 0.97
A motif preferred adenine base editor with minimal bystander and off-targets editing 0.88
Tailoring Cas12a functionality with a user-friendly and versatile crRNA variant toolbox 1.00
De novo design of hypercompact transcript degraders by engineering substrate-specific toxins and Cas6-CBS system 1.00
Discovery of CRISPR-Cas12a clades using a large language model 0.94
Dual-key cooperatively activated DNA regulator for controlling mitochondria-lysosome interactions 1.00
Matrix regulation: a plug-and-tune method for combinatorial regulation in 0.95
Structural insights into Type II-D Cas9 and its robust cleavage activity 1.00
Self-splicing RNA circularization facilitated by intact group I and II introns 1.00
Identification of a key nucleotide influencing Cas12a crRNA activity for universal photo-controlled CRISPR diagnostics 1.00
Amino acid transporters mediate autonomous delivery of nanoparticle vehicles into living plants 0.73
The PAZ pocket and dimerization drive CpAgo’s guide-independent and DNA-guided dual catalysis 1.00
Refined DNA repair manipulation enables a universal knock-in strategy in mouse embryos 1.00
Regulating cleavage activity and enabling microRNA detection with split sgRNA in Cas12b 1.00
Mechanisms and engineering of a miniature type V-N CRISPR-Cas12 effector enzyme 1.00
Scalable modulation of CRISPR‒Cas enzyme activity using photocleavable phosphorothioate DNA 1.00
An orthogonal transcription mutation system generating all transition mutations for accelerated protein evolution in vivo 1.00
Cas12a cleavage mediated lateral flow assay enables multiplex and ultra-specific nucleic acid detection 1.00
Benchmarking metabolic RNA labeling techniques for high-throughput single-cell RNA sequencing 1.00
1 1.00
De novo assembly and delivery of synthetic megabase-scale human DNA into mouse early embryos 1.00
5 4.36
Structural basis of AtCas9 recognition of PAM mutants in underwound DNA topology 1.00
Structural insight into IscB’s RNA-lid-based inactivation mechanism 0.36
Improving the efficiency of high-fidelity Cas9 by enhancing PAM-distal interactions 1.00
An anti-CRISPR targets the sgRNA to block Cas9 and guides the design of enhanced genome editors 1.00
Computational design of a high-precision mitochondrial DNA cytosine base editor 1.00
1 1.00
Solar-driven biosynthesis of chemicals from phosphite-rich wastewater and carbon dioxide 1.00
1 1.00
Indopexines A and B: Two Prenylated Isoindoline Alkaloids from the Fungus Aspergillus sp. TJ507 1.00
1 1.00
Overexpression of the pioneer transcription factor Nr5a2 promotes the development of mouse somatic cell nuclear transfer embryos 1.00
1 1.00
Development of an RNA aptamer-assisted CRISPR/Cas9 system for efficiently generating and isolating Cas9-free mutants in plant 1.00
8 7.88
Iterative Genome Engineering Platform Enables Efficient Sucrose Biosynthesis From CO2 in Photosynthetic Synechococcus elongatus UTEX 2973 1.00
<atl>Knocking Out Two Polyphenol Oxidase Genes Significantly Improves Recombinant Protein Purification in iNicotiana benthamiana/i</atl> 0.88
Cas9-Embedding Hyperactive TadA8e Confers Efficient and Highly Specific A-To-G Base Editing in Rice 1.00
TKC-MC: An Effective Strategy for Generating Heritable Heterozygous Mutations in Essential Genes in Rice 1.00
Versatile Applications of CRISPR-Based Programmable T-DNA Integration in Plants 1.00
Transgene-Killer-CRISPR version 2 (TKC2) eliminates occasional transgene escape by coupling with a RUBY reporter 1.00
Rice-derived SARS-CoV-2 glycoprotein S1 subunit vaccine elicits humoral and cellular immune responses 1.00
Bioengineered poplar fibres via PagGLR2.8 editing: A synergistic design for high-performance biocomposites 1.00
7 6.73
Multiplex gene editing enables the multibiofortification of essential vitamins and other health-promoting phytonutrients in tomato 1.00
An acetyltransferase family required for biosynthesis of diverse marine carotenoids 0.83
An ADAR2-mimic base editor for efficient C-to-U RNA editing in vivo 1.00
Versatile Xenopus tropicalis model with targeted integration of human BRAFV600E 1.00
STAGE: A compact and versatile TnpB-based genome editing toolkit for Streptomyces 0.90
Engineered Un1Cas12f1 with boosted gene-editing activity and expanded genomic coverage 1.00
In vivo generation of CAR macrophages via the enucleated mesenchymal stem cell delivery system for glioblastoma therapy 1.00
1 1.00
Engineered geminivirus replicons enable rapid in planta directed evolution 1.00
8 6.98
Uncovering functional variants using a high-efficiency PE3-based screening platform 0.96
PlasmidGPT: A generative framework for plasmid analysis and generation 0.88
Mitochondrial heterogeneity drives the evolution of fungicide resistance in Phytophthora sojae, with associated fitness trade-offs 1.00
Targeting transthyretin by one Cas9 variant with superfidelity and broad compatibility 1.00
Renal clearable CRISPR nanosensor targeting mitochondrial DNA mutation for noninvasive monitoring of tumor progression and metastasis 1.00
Antibiotic stress–induced hormesis in phytoplankton and bacteria through their mutual cooperation 1.00
BioFuse: A programmable timer switch of gene expression 1.00
Integrating incompatible tandem photobiocatalysis in artificial cells enables metabolic modulation of natural cells 0.14
1 1.00
Coordinated regulation using small-molecule drugs enables controlled therapeutic genome editing and enhanced genomic precision in situ 1.00
2 1.93
Assessing target genes for homing suppression gene drive 1.00
A bacterial gene acquired by parasitoid wasps contributes to venom secretion against host defence 0.93
2 1.95
Multimodular flavobacterial enzymes specialised in coordinated decomposition of cellulose and alginate in brown algal cell walls 0.95
Cellular membrane protein MipA from E.coli Nissle 1917 protects against Salmonella infection 1.00
27 23.78
Hydroxyapatite-facilitated microalgae-bacteria aggregates enable robust aeration-free nutrient removal from saline domestic wastewater 1.00
Mechanisms for the phytohormone-elevated performance of a continuous-flow baffled cyanobacterial photo-bioreactor for antibiotic removal and lipid production 1.00
Extracellular polymeric substances trigger microalgae flocculation in a combined and green flocculation-flotation harvesting process 1.00
Illumination-Induced Restructuring of Extracellular Polymeric Substances from Klebsiella Sp. HDJY-1 Drives Indirect Photodegradation of Thifensulfuron-methyl 1.00
Mechanistic responses of coccolithophores to exposure to the marine pollutant atrazine 1.00
Unlocking microbial synergy in microalgae-bacteria granules: RSM-driven optimization and lifecycle microbial metagenomics for high-ammonia wastewater treatment 0.91
Water lifting aerators control algal growth in drinking water reservoirs: Performance, mechanism and application 1.00
Effect of Nitrosomonas europaea on Chlorella vulgaris in bio-hydrogels for startup of microalgal-bacterial granular sludge: Performance and microscopic mechanism 1.00
Stabilizing photogranule systems under low-light and limited-aeration: From operational strategy to underlying mechanism 1.00
Biomass Ratio Regulates Methane Conversion and Carbon Fixation in a Methanotrophs-Microalgae Symbiotic System: Efficiency Optimization and Mechanisms Driven by Co-metabolism 1.00
Legacy effect of repeated stimulation by Indole-3-Acetic Acid on the rapid attachment of microalgae biofilms 0.88
How Chlorella vulgaris remove florfenicol from wastewater—— from the aspects of kinetics, mechanism, limiting factors and long-term regulation 0.86
Coupling Microalgae-based Biochar with MBGS Enhances Microbial Synergy and Multi-Pollutant Removal from Saline Aquaculture Wastewater 1.00
Photocatalysis-fueled algae-bacteria mutualism enables P450 enzyme-induced nitrite-free anammox for sustainable nitrogen removal 1.00
Comparative study of CO₂ nanobubbles and macrobubbles: Effects on water chemistry, microalgal growth, and carbon utilization 0.17
Sticky or thrifty: Divergence in extracellular glycometabolic architecture underpins contrasting fungal bioflocculation strategies 1.00
Crosstalk with Chlorella sp. reshapes the environmental fates of aspartame: From stress responses to contaminant destabilization 0.78
Community succession and protein enhancement in a mixed methanotroph-microalgae system with stepwise increase of ammonium loading - Inhibition and adaptation 0.40
Bifunctional fungi trade off denitrification and algicidal performance to inhibit algal growth and control algal bloom: Denitrification-algicidal interactions, organic matter dynamics, and raw water treatment 1.00
Using bio-based CaCO3 functionalized sediment to simultaneously remove algae and COD through adsorption and sedimentation in water source reservoirs 1.00
Microalgae-mediated treatment of steel industry reverse osmosis concentrate integrated with flue gas carbon fixation: From laboratory selection to pilot-scale verification 1.00
Hormetic effect of dissolved organic matter from pig manure anaerobic digestion effluents on Chlorella sp.: Physiological and transcriptomic responses 0.82
Synergistic microalgal-bacterial interactions enhance nitrogen removal in membrane-aerated biofilm photoreactors treating aquaculture wastewater under salt stress: Insights from metagenomic analysis 0.17
Semi-continuously operated single strain microalgal-bacterial biofilm for nutrients removal: microbial succession and performance improvement over extended non-axenic operation 1.00
Layer-specific photo-metabolic specialization of encapsulated microalgae: A strategy for synchronous multi-nitrogen elimination from wastewater 1.00
Reduction of Antibiotics and Antibiotic Resistance Genes in Simulated-Sunlight-Supported Counter-diffusion Bacteria-Algae Biofilms: Interface Properties and Functional Gene Responses 1.00
CO2 Drives Ecological Shifts through Asymmetric Selection in Microalgae-Bacteria Granular for Enhanced Wastewater Treatment and Carbon Fixation 0.81

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