Biochemistry and Cell Biology articles for Japan

Time frame: 1 June 2025 - 30 May 2026

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Count: 196

Article ‘Count’ for Biochemistry and Cell Biology.

Journal Count Share
1 1.00
Development of a three-dimensional experimental vascular model with smooth muscle cell-derived cross-linked elastic fiber assembly 1.00
1 0.10
Bi-allelic ATG12 variants impair autophagy and cause a neurodevelopmental disorder 0.10
1 1.00
Neonatal Thymic Dynamics Influence Autoimmune Pathology by Shaping the Suppressive Potential of Regulatory T Cells 1.00
6 4.06
Vinyltrimethylsilane Chemical Ionization Tandem Mass Spectrometry Separates Methoxyphenylpiperazine Isomers 1.00
Gap-Controlled Infrared Absorption Spectroscopy: A Unique Interface-Sensitive Spectroscopy Based on the Combination of Linear Spectroscopy and Multivariate Curve Resolution 1.00
Sequencing of DNA Mixtures Using Liquid Chromatography─Postactivated Plasma Electron Detachment Dissociation Mass Spectrometry 0.50
Comprehensive Glycan Mapping of Intact Human Erythropoietin by Reversed-Phase Liquid Chromatography–Mass Spectrometry 0.33
An Approach for Measuring Extracellular Vesicle Size Using the Attenuation-Velocity Change Ratio of SH-SAW Biosensors 0.22
Proposed Method for Label-Free Separation and Infrared Spectroscopy of Carbonyl-Containing Micro- and Nanoparticles Using Mid-Infrared Optical Force 1.00
4 3.38
A Pseudokinase Catalyzes Nitrile Formation in the Biosynthesis of a Potent Marine Toxin 0.67
PCA‐Based Database Mining Enables the Discovery of Bacterial Carbene Transferases for Stereodivergent Cyclopropanation 1.00
Enzyme Immobilization in Porous Crystals via Cage Encapsulation 1.00
A Method for Constructing Nucleosome Arrays with Spatially Defined Histone PTMs and DNA Damage 0.71
1 0.01
Activated T cell extracellular vesicle DNA transfer enhances antigen presentation and anti-tumor immunity 0.01
1 0.01
Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice 0.01
3 2.50
Acid-catalyzed esterification and biotin/fluorescent labeling of glutathione polysulfides based on stability under heating and pH change 1.00
Hydroxylated iodinated boron clusters: a tunable platform for enhanced membrane transport and biocompatibility 0.75
Triplex formation-mediated fluorescence sensing of single bulge nucleotide-containing double-stranded RNAs using thiazole orange base surrogate-carrying PNAs 0.75
3 1.19
Structural basis of the residence time of adenosine A2A receptor ligands revealed by NMR 1.00
Wavelength dependent photochemistry of an iron dinitrogen hydride complex ivia/i multiple spectroscopies – competing ejection of axial ligands 0.08
Double crossed? Structural and computational studies of an unusually crosslinked haem in iMethylococcus capsulatus/i cytochrome P460 0.11
1 0.20
Mitochondrial function regulates cell growth kinetics to maintain mitochondrial homeostasis 0.20
2 0.19
Spatiotemporal mapping of the contractile and adhesive forces sculpting early C. elegans embryos 0.07
Tissue-scale mapping reveals a central role of hepatoblasts in the regulation of fetal liver hematopoiesis and stem cell maintenance 0.11
1 0.07
UPR deficiency leads to poor growth, aneuploidy, and a trade-off between ER and general proteostasis in yeast 0.07
1 1.00
Cyclometalated Iron(II) Thiolate Complexes Featuring Diazine Rings: π-Acceptor Character of the C,N-Chelate Moiety 1.00
37 34.60
Highly branched complex-type N-glycans on integrin β1 in extracellular vesicles enhance the binding of sEVs to laminin on recipient cells 1.00
A novel autopolysialylation activity of the ganglioside sialyltransferase ST8Sia5 regulates its secretion and enzyme activity 1.00
Fungal oxidative stress tolerance depends on peroxiredoxin PrxA-mediated redox signaling to mitochondrial cytochrome c peroxidase Ccp1 0.06
Golgi-derived phosphatidylinositol 4-phosphate is crucial for organization of the preautophagosomal structure 1.00
C-Mannosyl tryptophan dynamics in a mouse model of the peritoneal dissemination of ovarian cancer 1.00
Insights into the recognition of cyclic α-(1→6)-glucan by a solute-binding protein of an ABC transporter from Tepidibacillus decaturensis 1.00
PA14 domain of glycosyltransferase B4GALNT3 is a lectin that binds to sulfated glycan ligands 0.78
SLC52A1 is a neofunctionalized primate urate transporter enabling intestinal urate secretion 1.00
Acetic acid induces proteasome storage granule formation and inhibits proteasomal proteolysis: Comparison with other induction conditions 1.00
Structural insights into glycoside hydrolase family 1 β-glucosidase: Selective oligosaccharide hydrolysis, synthesis, and product profiling 0.75
Preferential use of alkyl-acyl phosphatidylinositol for GPI biosynthesis and diagnostic potential of lipidomics for inherited GPI deficiencies 0.78
A conformation-dependent hydrophobic degron determines Rab9a-mediated vesicular trafficking 1.00
Signal peptide peptidase– and SPP-like 3–dependent shedding of α1,6-fucosyltransferase differentially affects core fucosylation 1.00
Mannose metabolic pathway senses glucose supply and regulates cell fate decisions 1.00
Palmitic acid induces UCP1-independent mitochondrial depolarization specifically in brown adipose tissue 1.00
A neural glycan HNK-1 is transferred to recipient cells via small extracellular vesicles 1.00
Enzymatic basis of branching and extension of O-Man glycans for keratan sulfate biosynthesis 0.75
Unique bifunctional α-sialidase/β-N-acetylgalactosaminidase from Bifidobacterium bifidum acting on the Sda antigen 1.00
Development of a VHH that inhibits the binding of neuronal pentraxin 2 to a postsynaptic glutamate receptor, AMPAR 1.00
Cryo-EM Structure of the ATP11C Q79E Mutant Reveals the Structural Basis for Altered Phospholipid Recognition 1.00
Structural characterization of zebrafish Ngly2, an ovary-enriched acid PNGase required for egg free glycan production 1.00
Divergent acetyl-CoA binding modes mediate allosteric inhibition of bacterial hybrid-type malic enzymes 1.00
Csk-dependent and independent control of Src family kinases directs neuronal migration in the developing cerebral cortex 1.00
The non-conserved integrin cytoplasmic region determines integrin subtype-specific characteristics by modulating talin1 binding kinetics 1.00
AlphaFold3-guided optimization of a photoactivatable endonuclease for top-down genome engineering 1.00
DUF-721 and N-terminal extension of the helicase loader DciA bind ssDNA to promote replicative DnaB helicase loading in Caulobacter crescentus 1.00
Cgm1 is a β-galactoside α-(1 → 4)-mannosyltransferase involved in the biosynthesis of capsular glucuronoxylomannogalactan in Cryptococcus neoformans 1.00
A unique gating mechanism revealed by the cryo-EM structure of monomeric ATP9A flippase 0.75
Proteasomal regulation of ASK family kinases dictates cell fate under hyperosmotic stress 1.00
Structural basis of transglucosylation in dextran dextrinase, a homolog of anomer-inverting GH15 glucoside hydrolases 1.00
Secretory autophagy mediates lysosomal and autophagic degradation for α-synuclein proteostasis 1.00
Structural basis of cuproenzyme nitrite reduction at the level of a single hydrogen atom 1.00
Phosphorylation-mediated Regulation of the NADPH-dependent Glutamate Dehydrogenase, SpGdh1, from Schizosaccharomyces pombe 1.00
Loss of integrin alpha7-mediated signaling induces a dendritic cell-like phenotype in macrophages cultured on laminin-211/221 isoforms 0.93
Single-subunit RNA polymerases, KpnP, Ro45Iw, and CD23823, with precise terminal synthesis 0.80
Maintenance of proper phosphatidylinositol-4-phosphate level by Stt4 and Sac1 contributes to vesicular transport to and from the plasma membrane 1.00
The binding sites of carbon dioxide, nitrous oxide, and xenon reveal a putative exhaust channel for bovine cytochrome c oxidase 1.00
12 7.14
Spectrin coordinates cell shape and signaling essential for epidermal differentiation 0.13
Regulation of cell dynamics by rapid integrin transport through the biosynthetic pathway 0.06
Endoplasmic reticulum patterns insect cuticle nanostructure 1.00
Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles 0.13
LLP1 is a pyrophosphatase involved in homeostasis/quality control of dolichol-linked oligosaccharide 0.87
ATG conjugation–dependent/independent mechanisms underlie lysosomal stress–induced TFEB regulation 0.80
The mitophagy receptors BNIP3 and NIX mediate tight attachment and expansion of the isolation membrane to mitochondria 0.63
Mechanical control of osteoclast fusion by membrane-cortex attachment and BAR proteins 1.00
The autophagy protein ATG-9 regulates lysosome function and integrity 0.20
Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin 1.00
Sorting nexin 10 regulates lysosomal ionic homeostasis via ClC-7 by controlling PI(3,5)P2 0.33
ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates 1.00
2 0.17
Hepatic glutathione depletion ameliorates MASLD through selective protein oxidation and inhibition of lipogenesis 0.11
Plasminogen Activator Inhibitor-1 promotes aortic aging-like pathophysiology in humans and mice 0.06
1 0.02
Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2 0.02
4 3.20
Peripheral cholecystokinin promotes thermogenesis via vagal afferent signalling, hypothalamic oxytocin and sympathetic outflow to brown adipose tissue 1.00
MCT1‐mediated bidirectional propionate transport across human placental syncytiotrophoblast layer: insights from a trophoblast stem cell‐derived barrier model 1.00
6-Methylsulfinylhexyl isothiocyanate activates carbonic anhydrase-dependent HCO3−/H+/Na+/Ca2+ transport via SLC4As–NHE–NCX–PMCA axis in odontoblasts 1.00
Two distinct mechanisms for GlyH‐101 block of the CFTR chloride channel 0.20
6 4.27
In Vitro Evolution of the Adenosine A2A Receptor Based on an Antagonist Binding Using a Ribosome Display 1.00
Low-Background Cancer Imaging with a Bioorthogonal Fluorescence Probe and Engineered Reporter Enzyme Bearing a Targeting Moiety 1.00
Refining the Substrate-Cofactor Disposition Model of Hyoscyamine 6β-Hydroxylase Catalysis Using Hyoscyamine Analogs 0.08
N-Oxide-Driven Heme-Activatable Biomolecule Labeling for Visualization of Labile Heme in Living Cells and Mouse Brain 1.00
Coprecipitated Enzyme-Encapsulated Covalent Organic Frameworks for Biocatalysis 0.18
A Nucleic Acid Prodrug That Activates Mitochondrial Respiration, Promotes Stress Resilience, and Prolongs Lifespan 1.00
3 2.17
FOXF1/2 establish a senescence-specific enhancer landscape to activate the pro-inflammatory senescence-associated secretory phenotype 1.00
Monitoring the complexity and dynamics of mitochondrial translation 1.00
Biochemical reconstitution of sister chromatid cohesion establishment during DNA replication 0.17
1 0.45
Visualization of the Assembly of a Two-Component Pore-Forming Toxin on a Target Membrane 0.45
4 2.01
Universal transcriptomic hallmarks of mammalian ageing and mortality 0.14
The dynamic basis of G-protein recognition and activation by a GPCR 0.95
Designing allosteric modulators to change GPCR G protein subtype selectivity 0.07
Maternal iron deficiency causes male-to-female sex reversal in mouse embryos 0.86
2 1.09
The atypical E3 ligase HOIL-1 safeguards the ribosome during cellular stress 0.09
Antagonistic stem cell fates under stress govern decisions between hair greying and melanoma 1.00
3 2.04
Oncometabolite 5-IP7 inhibits inositol 5-phosphatase to license E-cadherin endocytosis 0.09
Membrane-domain compartmentalization of active GPCRs by β-arrestins through PtdIns(4,5)P binding 1.00
Insights into G-protein coupling preference from cryo-EM structures of Gq-bound PTH1R 0.95
2 0.11
Emergence of specific binding and catalysis from a designed generalist binding protein 0.02
Stepwise and reversible assembly of [2Fe–2S] rhombs to [8Fe–8S] clusters and their topological interconversions 0.09
51 32.39
Non-diffusive slow heat dissipation induces high local temperature in living cells 1.00
Structural basis and physiological significance of non-canonical G coupling to the melatonin MT receptor 0.50
Diverse mechanisms of translation arrest by a Clostridia ribosome stalling peptide CliM 0.42
ZO-1 shuttles between apical junctional complexes and podosomes by riding ERK activation waves 1.00
Single-molecule kinetic exploration of functional sub-states in an evolving phosphotriesterase 0.14
Proteasome alteration between epithelial and hematopoietic cells facilitates positive selection of CD8 T cells 0.13
Shared structural mechanisms of alternating access between the secondary peptide transporter SbmA and ABC transporters 0.14
Adipocytes signal to recruit specific mRNAs from surrounding cells to restore expression deficits 0.03
Structures of respiratory supercomplexes and ATP synthase oligomers in mammalian mitochondrial inner membrane 1.00
Impaired -Synuclein aggregate clearance in neuronal cells drive their spread to microglia through tunneling nanotubes 0.20
STIM1-Mitofusin2 interactions tether mitochondria and melanosome contacts that promote melanosome maturation 1.00
Cross-species gene redesign leveraging ortholog information and generative modeling 1.00
From single-sequences to evolutionary trajectories: protein language models capture the evolutionary potential of SARS-CoV-2 0.05
Conformational biosensors delineate endosomal G protein regulation by GPCRs 0.17
Ligand-dependent Wnt signaling promotes gastric cancer metastasis through hyaluronan expression in microenvironment 0.77
Versican expression from lung fibroblasts suppresses pulmonary fibrosis 0.05
A universal polyphosphate kinase powers in vitro transcription 0.92
Spatiotemporal regulation of MKK4 dictates switch-like JNK activation and binary cell-fate decisions 1.00
Structural basis for the subtype-selectivity of KCa2.2 channel activators 0.10
Geometry-preserving vector field reconstruction of high-dimensional cell-state dynamics using ddHodge 1.00
Stable de novo protein design via joint conformational landscape and sequence optimization 0.10
Real-time capture of domain movements during copper amine oxidase catalysis by mix-and-inject serial crystallography 1.00
HIV-induced sialoglycans on infected CD4+ T cells promote immune evasion from myeloid cell-mediated killing 0.07
Collision-induced ribosome degradation driven by ribosome competition and translational perturbations 1.00
Mechanistic insights into single-stranded DNA degradation by lysosomal exonucleases PLD3 and PLD4 from structural snapshots 1.00
Multi-faceted roles of β-arrestins in G protein-coupled receptor endocytosis 0.07
Efficient cellular transformation via protein delivery through the protrusion-derived extracellular vesicles 0.89
Regulated TRESLIN-MTBP loading governs initiation zones and replication timing in human DNA replication 0.90
Phosphorylation-coupled autoregulation of TANGO1 and Sec16A maintains functional ER exit sites 1.00
Mechanochemical mechanism underlying intercellular Ca2+ wave propagation and its crucial role in apoptotic cell extrusion 1.00
Optineurin is an adaptor protein for ubiquitinated substrates in Golgi membrane-associated degradation 0.91
Structural basis of K11/K48-branched ubiquitin chain recognition by the human 26S proteasome 0.03
MSL10 is a high-sensitivity mechanosensor in the tactile sense of the Venus flytrap 0.95
Repeatability of protein structural evolution following convergent gene fusions 1.00
The DNA replication machinery transmits dual signals to prevent unscheduled licensing and execution of centrosome duplication 0.92
Evidence that mitochondria in macrophages are destroyed by microautophagy 1.00
Modeling of T cell-mediated autoimmune pituitary disease using human induced pluripotent stem cell-originated organoid 1.00
An iPSC-based in vitro model recapitulates human thymic epithelial development and multi-lineage specification 0.95
Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol 0.20
Conservation of dark CPD photolyase function in blind cavefish 0.09
Glial reactivity and cognitive decline follow chronic heterochromatin loss in neurons 0.25
A cytokine-based designer enzyme with an abiological multinuclear metal center exhibits intrinsic and extrinsic catalysis 1.00
Senescence-associated lysosomal dysfunction impairs cystine deprivation-induced lipid peroxidation and ferroptosis 1.00
Biomechanical control of vascular morphogenesis by the surrounding stiffness 1.00
Ancestral sequence reconstruction as a tool for structural analysis of modular polyketide synthases 0.95
Te and Fe nuclear resonance vibrational spectroscopic characterization of intermediate spin state mixed-valent dimers 0.22
Cellular crosstalk mediated by TGF-β drives epithelial-mesenchymal transition in patient-derived multi-compartment biliary organoids 0.05
Sex difference in BAT thermogenesis depends on PGC-1α–mediated phospholipid synthesis in mice 1.00
Body temperature regulates glucose metabolism and torpid behavior 1.00
Muscle AMP deaminase activity was lower in Neandertals than in modern humans 0.21
Engineering of ATP synthase for enhancement of proton-to-ATP ratio 1.00
1 0.13
Age-dependent Zap70 expression in thymocytes regulates selection of the neonatal regulatory T cell repertoire 0.13
1 0.08
AlphaFold as a prior: experimental structure determination conditioned on a pretrained neural network 0.08
1 1.00
Phase separation promotes Atg8 lipidation and vesicle condensation for autophagy progression 1.00
1 0.29
Role of Pcdh15 in the development of intrinsic polarity of inner ear hair cells 0.29
17 11.98
Bleb expansion requires transient membrane invaginations that sequester curvature-preferring proteins 1.00
Measurement of atomic scattering factors by cryoelectron microscopy 0.08
Structural insights into biased signaling at chemokine receptor CCR7 1.00
Suppression rather than activation of the integrated stress response (GCN2–ATF4) pathway extends lifespan in the fly 0.20
Serotonin potentiates presynaptic calcium currents and transmitter release at cortical synapses 1.00
Host ESCRT machinery orchestrates the assembly of tomato spotted wilt virus ribonucleoproteins 1.00
GalNAc-T13 maintains neurite architecture and memory retention via O-GalNAc glycosylation of seizure protein 6 0.25
The role of the tryptophan-rich allosteric network and sodium egress in GPCR activation 0.45
High-speed atomic force microscopy reveals a surface-catalyzed elongation mechanism of the fungal functional amyloid hydrophobin RolA 1.00
De novo discovery of bicyclic cysteine-rich peptides targeting gasdermin D 0.88
Widespread promiscuous alkaline phosphatases underscore ancient microbial phosphite utilization 0.20
Structural insights into the G-protein subtype selectivity revealed by human sphingosine-1-phosphate receptor 3–Gq complexes 1.00
Sirt6 prevents the age-related decline of H2S through the control of one-carbon metabolism 0.04
Differential O-glucose elongation on a specific EGF repeat within the canonical ligand–binding domain regulates DLL1/4-NOTCH1 signaling 0.88
RyR1-mediated Ca2+-induced Ca2+ release plays a negligible role in excitation–contraction coupling of normal skeletal muscle 1.00
Exploring glycoform-dependent dynamic modulations in human immunoglobulin G via computational and experimental approaches 1.00
SARS-CoV-2 uptake and inflammatory response in senescent endothelial cells are regulated by the BSG/VEGFR2 pathway 1.00
2 0.31
Cohesin drives chromatin scanning during the RAD51-mediated homology search 0.09
Intercellular communication in the brain through a dendritic nanotubular network 0.22
8 3.83
A cross-tissue physicochemical causal chain underlying vertebrate mandibular morphogenesis 0.92
Piezo1-mediated mechanohydraulic control of cell volume drives cardiac morphogenesis 0.25
Glomerular routing of tumor-derived extracellular vesicles substantiates urinary biopsy 1.00
Cryo-EM structure of human AQP11 reveals a trimeric architecture with a large pore 1.00
The structure of an actin nucleus stabilized by villin 0.06
NAD+ reverses Alzheimer’s neurological deficits via regulating differential alternative RNA splicing of EVA1C 0.03
Formation control between leader and migratory follower tissues allows coordinated growth 0.53
Discovery of a functionally selective serotonin receptor (5-HT1AR) agonist for the treatment of pain 0.05
2 0.52
Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease 0.07
Ritscher-Schinzel syndrome can be characterized as an endosomal recyclinopathy 0.45
2 1.57
Stress-induced OMA1-mediated cleavage of AIFM1 suppresses cell growth by controlling mitochondrial OXPHOS activity 0.57
CaMKII nucleates an osmotic protein supercomplex to induce cellular bleb expansion 1.00
1 1.00
Enrichment of horizontally transferred gene clusters in bacterial extracellular vesicles via non lytic mechanisms 1.00
6 6.00
Metal-Ion–Monosaccharide Interactions: Selective Formation of a Specific Coordination Motif in Carbohydrate Recognition 1.00
Free Energy Calculation Method Based on Enhanced Sampling of Diverse Protein Conformations Predicted by Artificial Intelligence 1.00
Real-Time Sub-Molecular Visualization of DNA Folding Using a Hybrid High-Speed AFM and Optical Tweezers System 1.00
Membrane Constriction by Dynamin through GTP-Driven Conformational Changes from Coarse-Grained Molecular Dynamics Simulations 1.00
Compact Conformation of Ba2+-Beauvericin Complex by Triple Cation-π Interactions: Insight into Ion Transport Mechanism from Gas-Phase Structures 1.00
Structural Changes in the Retinal Chromophore and Ion-Conducting Pathway of an Anion Channelrhodopsin iGt/iACR1 1.00

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