Biochemistry and Cell Biology articles for Switzerland

Time frame: 1 June 2025 - 30 May 2026

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Count: 137

Article ‘Count’ for Biochemistry and Cell Biology.

Journal Count Share
3 1.85
HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion 0.01
In vitro characterization of endothelial damage from rapid multiaxial mechanical loading 0.83
Mineralized osteoblast-derived exosomes and 3D-printed ceramic-based scaffolds for enhanced bone healing: A preclinical exploration 1.00
9 3.84
Cryogenic Gas-phase IR Spectroscopy on a Commercial Ion Mobility-Mass Spectrometry Platform 0.11
Selective Near-Infrared Fluorescent Chemosensors for Human Carboxylesterase 1 Activity 0.40
Orthogonal Investigation at Single-Particle and Ensemble Levels Uncovers Lipoprotein-Extracellular Vesicle Binding 0.21
A High-Density Microchamber Array for the Analysis of Extracellular Vesicles Derived from Single Cells under Drug Treatment 1.00
Experimental and Theoretical Insights into Nanoscale AFM-IR Imaging of Complex Heterogeneous Structures 0.14
Integrating Multiple MS Techniques for in-Depth Antibody Glycosylation Analysis: Revealing Glycosylation-Dependent Structural and Functional Properties 0.56
Beyond Liquid Chromatography: Cyclic Ion Mobility Spectrometry for Phosphorothioate Diastereomer Separation in siRNA 1.00
Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides 0.11
Enhancing Sensitivity in Low-Load Proteomics Orbitrap Workflows via SLIM Integration 0.31
6 3.30
A Pseudokinase Catalyzes Nitrile Formation in the Biosynthesis of a Potent Marine Toxin 0.33
Structural Mechanism of an Efficacy Photoswitch Targeting the β2-adrenergic Receptor 0.65
Fluorinated Glycan Frameshifts: Automated Synthesis Expedites the Study of Glycan-Protein Interactions by 19F-BioNMR 0.36
The Parkinson's Disease Drug Tolcapone and Analogues are Potent Glycomimetic Lectin Inhibitors of Pseudomonas aeruginosa LecA 0.33
Hyperstable, Minimal‐Length, and Blunt‐Ended Collagen Heterotrimers 0.94
AI.zymes: A Modular Platform for Evolutionary Enzyme Design 0.69
2 0.77
Light-directed evolution of dynamic, multi-state, and computational protein functionalities 0.71
Membrane potential mediates the cellular response to mechanical pressure 0.06
1 0.59
DGAT-driven futile lipid cycling has a pronounced, yet concealed, thermogenic function 0.59
2 1.63
Going full circle: dynamic covalent enzyme immobilisation via visually trackable boronate esters 1.00
Single-position ligand modifications tune CB2R activity by targeting the toggle switch 0.63
3 2.75
Arp2/3-dependent actin assembly shapes endosomes and promotes intracellular trafficking in fission yeast 1.00
The DEG/ENaC channel DEGT-1 is a proprioceptor of C. elegans foregut movement 0.75
Mosaic evolution of clathrin-mediated endocytosis in fungi 1.00
1 0.78
Tissue-scale mapping reveals a central role of hepatoblasts in the regulation of fetal liver hematopoiesis and stem cell maintenance 0.78
1 0.07
Sulfidation Unlocks Dual Reductive Pathways in Uranium Immobilization by Iron Sulfide 0.07
1 0.04
Long noncoding RNA SALTe1, microvascular ageing, and cardiac dysfunction 0.04
1 0.01
Antibody responses against bacterial glycans affinity mature and diversify in germinal centers 0.01
2 1.22
Disruption of GxxxG motifs in pATOM36 impairs biogenesis of the mitochondrial protein translocase of the outer membrane in Trypanosoma brucei 1.00
Preferential use of alkyl-acyl phosphatidylinositol for GPI biosynthesis and diagnostic potential of lipidomics for inherited GPI deficiencies 0.22
1 0.05
Bone marrow neutrophil density regulates myelopoiesis during obesity and weight loss 0.05
1 0.60
Electrodiffusion in cardiac intercalated disc nanostructures alters cell–cell action potential transmission via ephaptic coupling: A model study 0.60
2 1.71
Genetic Incorporation of Diverse Noncanonical Amino Acids for Histidine Substitution 1.00
Dinitrogen Cleavage and Hydrogenation by a Uranium Hydride Complex Enabled through Metal–Ligand Cooperativity 0.71
3 0.81
Mechanism of RACK1-dependent ZAKα activation at stalled and collided ribosomes 0.10
Mechanism of DNA entrapment by a loop-extruding Wadjet SMC motor 0.67
Interaction with AK2A links AIFM1 to cellular energy metabolism 0.05
8 2.43
Universal transcriptomic hallmarks of mammalian ageing and mortality 0.02
Dynamics of genetic and somatic trade-offs in ageing and mortality 0.12
Cell-type-targeted mitochondrial transplantation rescues cell degeneration 0.98
Polyamine-dependent metabolic shielding regulates alternative splicing 0.04
Computational design of metallohydrolases 0.06
Hepatic zonation determines tumorigenic potential of mutant β-catenin 0.01
Hijacking a bacterial ABC transporter for genetic code expansion 0.64
One-shot design of functional protein binders with BindCraft 0.55
3 1.36
Karyopherins remodel the dynamic organization of the nuclear pore complex transport barrier 0.29
The intrinsically disordered regions of organellophagy receptors are interchangeable and control organelle fragmentation, ER-phagy and mitophagy flux 1.00
ZNF280A links DNA double-strand break repair to human 22q11.2 distal deletion syndrome 0.07
2 1.34
Structures of ALG3/9/12 reveal the assembly logic of the N-glycan oligomannose core 0.79
Accurate single-domain scaffolding of three nonoverlapping protein epitopes using deep learning 0.56
2 1.45
Hydrophobic tuning with non-canonical amino acids in a copper metalloenzyme 1.00
Stepwise and reversible assembly of [2Fe–2S] rhombs to [8Fe–8S] clusters and their topological interconversions 0.45
45 23.20
CryoWriter: a robotic solution for improved Cryo-EM grid preparation 0.93
Structural basis of Ku-mediated activation of WRN exonuclease activity 0.11
Two-dimensional HRS condensates drive the assembly of flat clathrin lattices on endosomes 0.50
A divergent Plasmodium NEK4 acts as a key regulator driving the early events of meiosis 0.13
The vault associates with membranes in situ 0.08
Activation mechanism of the full-length histidine kinase LvrB from pathogenic Leptospira 0.46
Bacterial extracellular vesicles as recyclable nutrient reservoirs 0.02
Therapeutic potential of dihydronicotinamide riboside (NRH) on obesity and glucose intolerance in mice 0.69
Enhancing the performance of Magnets photosensors 0.80
Phosphoregulation of the novel hemi-arrestin MAPK scaffold Sms1 prevents untimely mating 1.00
Structural basis and regulation of GSDME pore formation 0.06
Structure of a pH-sensitive pentameric ligand-gated ion channel from the Sarcoptes scabies mite 0.22
Lifestyle change accelerates epigenetic ageing in King penguins 0.11
Decoding the substrate specificity landscape of a promiscuous enzyme through multi-substrate mutational scanning 1.00
Lack of MDA5 delays hematopoietic aging by modulating inflammaging and proteostasis in mice 0.11
Ultrathin liquid cells for microsecond time-resolved cryo-EM 1.00
OCT4 enhances the firing efficiency of late DNA replication origins in mouse embryonic stem cells 1.00
Targeted imaging of specialized plant cell walls by improved cryo-CLEM and cryo-electron tomography 1.00
Klebsiella ARO112 promotes microbiota recovery, pathobiont clearance and prevents inflammation in IBD mice 0.14
Lipid dependence of connexin-32 gap junction channel conformations 0.75
Development of a p62 biodegrader for autophagy targeted degradation 0.87
Vacuolar-type H+-ATPase-mediated extra-organellar buffering resolves mitochondrial dysfunction 0.08
Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality 0.02
GLYCO-BUILD: an enzymatic pipeline for the synthesis of peptides carrying eukaryotic N-glycans 1.00
Localized Wnt-signaling promotes asymmetric NuMA-dependent oriented divisions and unequal apportioning of mitochondria 0.14
Adherent cells sustain membrane tension gradients independently of migration 0.69
Investigating the neuronal role of the proteasomal ATPase subunit gene in neurodevelopmental proteasomopathies 0.02
The SMC Hinge is a Selective Gate for Obstacle Bypass 0.67
Spermine modulation of Alzheimer’s Tau and Parkinson’s α-synuclein: implications for biomolecular condensation and neurodegeneration 0.65
Large transient assemblies of Apaf1 constitute the apoptosome in cells 0.68
Global comparative structural analysis of responses to protein phosphorylation 0.29
The G1/S transition in mammalian stem cells in vivo is autonomously regulated by cell size 0.40
Investigating whether deep learning models for co-folding learn the physics of protein-ligand interactions 1.00
Bacterial RNA promotes proteostasis through inter-tissue communication in C. elegans 1.00
HSP90 differentially stabilizes plant ABCB-type auxin transporters on the plasma membrane 0.35
A robust platform streamlining aromatic noncanonical amino acid biosynthesis and genetic code expansion in Escherichia coli 0.11
Temporal control of human DNA replication licensing by CDK4/6-RB signalling and chemical genetics 0.33
Noncanonical roles of chemokine regions in CCR9 activation revealed by structural modeling and mutational mapping 0.56
Alpha-synuclein interacts with regulators of ATP homeostasis in mitochondria 1.00
MacroD1 sustains mitochondrial integrity and oxidative metabolism 0.82
Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling 0.13
Unequal segregation of mitochondria during asymmetric cell division contributes to cell fate divergence in sister cells in vivo 0.17
Enhancement of enzymatic activity by biomolecular condensates through pH buffering 1.00
Data-driven protease engineering by DNA-recording and epistasis-aware machine learning 0.83
Multiple intramolecular triggers converge to preferential G protein coupling in the CB2R 0.28
1 0.06
Cathepsin L-dependent positive selection shapes clonal composition and functional fitness of CD4+ T cells 0.06
1 0.00
The exposome of brain aging across 34 countries 0.00
3 1.42
AF2BIND: predicting small-molecule binding sites using the pair representation of AlphaFold2 0.17
A fully automated benchmarking suite to compare macromolecular complexes 1.00
MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony 0.25
1 0.11
The actin cortex acts as a mechanical memory of morphology in confined migrating cells 0.11
5 2.86
Rap1-mediated steric hindrance protects telomeres from MRX sensing 0.18
Evaluating generalization in protein–ligand cofolding methods 1.00
Structural mechanism for noncanonical GPCR signaling in the Hedgehog pathway 0.02
Structural phylogenetics unravels the evolutionary diversification of communication systems in gram-positive bacteria and their viruses 0.67
Structural basis for lipid transport at membrane contact sites by the IST2–OSH6 complex 1.00
3 0.57
Cdc42 interacts with chaperone Ydj1 to enhance its stability and partitioning during asymmetric cell division and aging in yeast 0.25
The Ync13–Rga7–Rng10 complex selectively coordinates secretory vesicle trafficking and secondary septum formation during cytokinesis 0.29
An arginine switch drives the stepwise activation of β-arrestin by CXCR7 0.03
2 0.64
Transposable element expression is associated with sex chromosome number in humans 0.07
Basal association of a transcription factor favors early gene expression. 0.57
1 1.00
Microscopy of Cavity-Induced Density-Wave Ordering in Ultracold Gases 1.00
5 1.26
Force patterning drives quasistratification and graded tissue-scale spatial order in auditory epithelia 0.33
Chromatin accessibility regulates age-dependent nuclear mechanotransduction 0.50
Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport 0.08
Reciprocity in dynamics of supramolecular biosystems for the clustering of ligands and receptors 0.13
Influenza A virus NS1 protein mimics oncogenic PI3K resulting in isoform specific cellular redistribution and activation 0.22
2 0.13
DNA-protein cross-links promote cGAS-STING–driven premature aging and embryonic lethality 0.04
Strengthening nucleic acid biosecurity screening against generative protein design tools 0.08
8 3.95
Tumor-targeted bispecific antibodies effectively inhibit oncogenic pathways while minimizing toxicity 0.11
CryptoBank: A resource for the identification and prediction of cryptic sites in proteins 0.95
TFEB coordinates autophagosome biogenesis and ribophagy during starvation via SQSTM1 0.07
Extrachromosomal circular DNA promotes inflammation and hepatocellular carcinoma development 0.70
Structure and assembly of the A-C linker connecting microtubule triplets in centrioles 0.82
Size-dependent temporal decoupling of morphogenesis and transcriptional programs in pseudoembryos 0.39
Ion channel structure and function of the MERS coronavirus E protein 0.11
Lamellar Schwann cells in the Pacinian corpuscle potentiate vibration perception 0.81
4 2.18
Atg18 interaction positions Atg2 for efficient lipid transfer into phagophore elongation 0.14
Hybrid endosomal coats contain different classes of sorting nexins 1.00
A dynamic feedback loop between retrograde sterol transport and TORC2 controls adaptation of the plasma membrane to stress 1.00
Lipid transporters E-Syt3 and ORP5 regulate epithelial ion transport by controlling phosphatidylserine enrichment at ER/PM junctions 0.04
2 1.91
A Transferable and Robust Computational Framework for Class A GPCR Activation Free Energies 0.96
The Arch from the Stones: Understanding Protein Folding Energy Landscapes via Bioinspired Collective Variables 0.95

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