Biochemistry and Cell Biology articles for Harvard University, United States of America (USA)

Time frame: 1 June 2025 - 30 May 2026

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Count: 124

Article ‘Count’ for Biochemistry and Cell Biology.

Journal Count Share
2 0.58
Noninvasive, Rapid, and Precise Identification of Esophageal Cancer via Salivary Extracellular Vesicle-Based Diagnosis 0.17
Engineering Liposomes with Cell Membrane Proteins to Disrupt Melanosome Transfer between Cells 0.42
1 0.03
HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion 0.03
1 0.06
Multiphysics‐Driven Assembly of Biomimetic Vesicles 0.06
2 0.93
Monoallelic PSMB8 variants cause PRAAS with immunodeficiency through impaired immunoproteasome assembly 0.01
Cross-omics risk scores of inflammation markers are associated with all-cause mortality: The Canadian Longitudinal Study on Aging 0.92
2 1.03
Molecular Analysis of Single Tumor-Derived Extracellular Vesicles with Improved Robustness and Accuracy 0.88
Time-Resolved “Barbecue” Förster Resonance Energy Transfer for Sensitive and Homogenous Detection of Alginate 0.15
1 0.62
Lysine Targeting Group-Transfer Chimeras for Proximity Induction 0.62
1 0.30
Aberrant Glycosylation of IgG in Children With Active Lupus Nephritis Alters Podocyte Metabolism and Causes Podocyte Injury 0.30
1 0.92
Proteasome subunit PSMD1 is a key therapeutic target in multiple myeloma 0.92
7 3.12
Mitochondrial control of glycerolipid synthesis by a PEP shuttle 1.00
Bringing the genetically minimal cell to life on a computer in 4D 0.08
Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux 0.21
Membrane potential mediates the cellular response to mechanical pressure 0.76
Molecular grammars of predicted intrinsically disordered regions that span the human proteome 0.23
Brain endothelial gap junction coupling enables rapid vasodilation propagation during neurovascular coupling 0.82
Optogenetics-enabled discovery of integrated stress response modulators 0.02
2 0.08
A metabolic atlas of mouse aging 0.04
Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice 0.04
1 0.08
Comparative single-cell lineage tracing identifies distinct adipocyte precursor dynamics in skin and inguinal fat 0.08
1 0.98
Evolutionary tuning of an auditory transduction channel 0.98
1 0.54
Long noncoding RNA SALTe1, microvascular ageing, and cardiac dysfunction 0.54
1 0.92
Longevity-promoting mitochondrial unfolded protein response activation requires elements of the PeBoW complex 0.92
8 1.70
Fidelity of DNA ligase I is sensitive to physiological Mg2+ level 0.57
Structure-Based Discovery of Selective Vaccinia-Related Kinase 1 Inhibitors and Fluorogenic Active-Site Probes 0.54
Deletion of Core 1 β3GalT-specific Molecular Chaperone (Cosmc) in murine intestinal epithelia leads to major alterations in glycocalyx and tumorigenesis 0.13
Electromotility can be disassociated from gating charge movement in outer hair cells of conditional alpha2 spectrin knockout mice 0.09
Sertad1 is elevated and plays a necessary role in neuron loss and cognitive impairment in a mouse model of Alzheimer’s disease 0.20
Identification of a novel GREMLIN1 uptake pathway in epithelial cells that requires BMP binding 0.08
Failed cellular surveillance enables pathogenic matrix deposition in a COL2A1-related osteoarthritis 0.02
CH−π interactions confer orientational flexibility in protein–carbohydrate binding sites 0.08
2 1.96
Energy stress activates AMPK to arrest mitochondria via phosphorylation of TRAK1 0.96
Close-up of vesicular ER exit sites by volume electron imaging using FIB-SEM 1.00
1 0.78
Hepatic glutathione depletion ameliorates MASLD through selective protein oxidation and inhibition of lipogenesis 0.78
2 0.53
FIP200 regulates plasma B cell differentiation via mitochondrial and heme homeostasis 0.52
Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2 0.01
4 1.73
Altered Intracellular Trafficking as a Mechanism for Prolonged Duration of G Protein-Coupled Receptor Activation 0.13
Enzyme-Activated Sugar-Coated Bifunctional Degraders 0.63
Proteomic Tracking Extracellular Vesicle RNA Interactors in Recipient Immune Cells through Orthogonal Labelings 0.09
Ultrahigh-Throughput Multiplexed Screening of Purified Protein from Cell-Free Expression Using Droplet Microfluidics 0.88
1 0.20
Clonal Hematopoiesis and Cardiovascular Outcomes in Older Women 0.20
1 0.09
Mechanisms of Podocyte Injury Due to Loss of the Nucleoporin NUP93. 0.09
3 1.12
BRD4-mediated ER membrane contact creates functionally distinct mitochondrial subtypes 0.12
Off-pore Nup98 condensates mobilize heterochromatic breaks and exclude Rad51 0.03
Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma 0.97
1 0.00
Single-cell characterization of the adult male hippocampus suggests a prominent, and cell-type specific, role for and in response to a social stressor 0.00
1 0.17
Urinary Exosome Isolation and Enrichment as Enabling Liquid Biopsy by Biologically Intact Exosome Separation Technology: BEST 0.17
7 1.96
Universal transcriptomic hallmarks of mammalian ageing and mortality 0.39
Human haematopoietic stem cells remember inflammatory stress 0.01
Thymic health consequences in adults 0.36
GlycoRNA complexed with heparan sulfate regulates VEGF-A signalling 0.61
Transient hepatic reconstitution of trophic factors enhances aged immunity 0.30
Hepatic zonation determines tumorigenic potential of mutant β-catenin 0.09
RNA N-glycosylation enables immune evasion and homeostatic efferocytosis 0.19
1 0.03
Democratizing protein language model training, sharing and collaboration 0.03
1 0.41
ZNF280A links DNA double-strand break repair to human 22q11.2 distal deletion syndrome 0.41
2 0.74
PCMT1 generates the C-terminal cyclic imide degron on CRBN substrates 0.52
Cell-selective multiplexed bioorthogonal noncanonical amino acid tagging for nascent proteomics 0.22
1 0.07
Emergence of specific binding and catalysis from a designed generalist binding protein 0.07
26 9.26
RNAs anchoring replication complex control initiation and firing of DNA replication 0.58
N-glycopedia: libraries for native N-glycan structural analysis 0.83
Probing molecular diversity and ultrastructure of brain cells with fluorescent aptamers 0.50
High-throughput single-vesicle imaging platform for direct extracellular vesicle profiling of human plasma 0.78
Structural basis of QueC-family protein function in qatABCD anti-phage defense 0.90
A pore-forming toxin initiates ABI1 complex switching to promote bacterial cell-to-cell spread 0.75
RPS19 and RPL5 haploinsufficient models reveal divergent ribosomal subunit controls of fetal hematopoiesis 0.04
Th17 cells require the DNA repair sensor xeroderma pigmentosum complementation Group C to control oxidative DNA damage in a murine model 0.07
Mutant ribosomal protein RPS15 drives B cell malignancy through oxidative stress and genomic instability 0.77
Ceramide disrupts TM9SF2-PGK1 axis to redirect PD-L1 trafficking and enhance antitumor immunity 0.06
Harnessing a germ‑free mouse gut bioreactor for directed evolution of probiotics to combat non-alcoholic fatty liver disease 0.10
Integrative epigenetics and transcriptomics identify aging genes in human blood 0.58
Small molecule splicing modulators that disrupt O-GlcNAc homeostasis 0.70
Capsaicin diet drives gut inflammation and exosomal miR-17-3p elevation in idiopathic short stature 0.06
Enantioselective protein affinity selection mass spectrometry (E-ASMS) 0.01
An unbiased comparison of 14 epigenetic clocks in relation to 174 incident disease outcomes 0.30
Tuning CAR-T cells by targeting cancer-associated glycan in pancreatic cancer 1.00
The genetic and biochemical basis of human leading strand synthesis 0.08
Investigating the neuronal role of the proteasomal ATPase subunit gene in neurodevelopmental proteasomopathies 0.02
A composite motif in calcimembrin/C16orf74 dictates multimeric dephosphorylation by calcineurin 0.52
Oligomeric HIV-1 integrase structures reveal functional plasticity for intasome assembly and RNA binding 0.19
Cardiomyocyte lncRNA Cpat maintains cardiac homeostasis and mitochondria function by targeting citrate synthase acetylation 0.08
Sensitive, high-throughput, metabolic analysis by molecular sensors on the membrane surface of mother yeast cells 0.05
Characterizing and engineering post-translational modifications with high-throughput cell-free expression 0.12
Development and application of GlycanDIA workflow for glycomic analysis 0.17
Exploitable mechanisms of antibody and CAR mediated macrophage cytotoxicity 0.00
1 0.06
Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation 0.06
2 0.02
The exposome of brain aging across 34 countries 0.01
The exposome of healthy and accelerated aging across 40 countries 0.01
3 0.76
eSIG-Net: an interaction language model that decodes the protein code of single mutations 0.03
AlphaFold as a prior: experimental structure determination conditioned on a pretrained neural network 0.12
AF2BIND: predicting small-molecule binding sites using the pair representation of AlphaFold2 0.61
5 3.38
Atomic models of the Toxoplasma cell invasion machinery 0.11
Translational activators align mRNAs at the small mitoribosomal subunit for translation initiation 0.70
Structure of the TXNL1-bound proteasome 1.00
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients 0.93
DMXL1 promotes recruitment of V1-ATPase to lysosomes upon TRPML1 activation 0.64
3 0.41
TMEM145 is a principal component of outer hair cell stereocilia 0.08
Endocytome profiling uncovers cell-surface protein dynamics underlying neuronal connectivity 0.10
Structural and functional basis of mechanosensitive TMEM63 channelopathies 0.23
1 0.86
The efficacy of longevity interventions in Caenorhabditis elegans is determined by the early life activity of RNA splicing factors 0.86
1 0.25
Age-associated decline of Coenzyme A leads to intestinal stem cells dysfunction via disturbing iron homeostasis 0.25
11 7.51
Acoel whole-body regeneration begins with spreading, multi-tissue ERK signaling downstream of neuregulin-1 1.00
Transsynaptic linking of calcium channels and postsynaptic receptors at a dyadic synapse 0.75
Comparative analysis of naked mole-rat thermogenesis and its potential to maintain euthermia in response to cold 0.69
Structures of folding intermediates on BAM show diverse substrates fold by a conserved mechanism 1.00
Fitting coarse-grained models to macroscopic experimental data via automatic differentiation 0.50
Chromatin accessibility regulates age-dependent nuclear mechanotransduction 0.21
Aging-associated differences in mammary tumor–initiating populations and immune evasion pathways in breast cancer 0.73
Unexpected heterogeneity and tissue-specific properties of the thymic hematopoietic antigen–presenting cell network 0.00
Wnt inhibition alleviates resistance to anti-PD1 therapy and improves antitumor immunity in glioblastoma 0.96
Surface delivery quantification reveals distinct trafficking efficiencies among clustered protocadherin isoforms 1.00
A mouse model of Jansen’s metaphyseal chondrodysplasia for investigating disease mechanisms and candidate therapeutics 0.68
4 2.73
Implantable living materials autonomously deliver therapeutics using contained engineered bacteria 0.77
Cohesin drives chromatin scanning during the RAD51-mediated homology search 0.79
GCN1 couples GCN2 to ribosomal state to initiate amino acid response pathway signaling 1.00
Evolutionary-scale enzymology enables exploration of a rugged catalytic landscape 0.18
7 1.96
The longevity effects of reduced IGF-1 signaling depend on the stability of the mitochondrial genome 0.05
Transcription activation mechanism of a noncanonical DNA damage response pathway by the WYL-activator, DriD 0.29
Transmembrane proteins mediate basal complex assembly and individual daughter cell formation in malaria parasites 0.57
The structure of an actin nucleus stabilized by villin 0.11
Programmed ribosomal frameshifting during PLEKHM2 mRNA decoding generates a constitutively active proteoform that supports myocardial function 0.03
Initiation of meiosis from human iPSCs under defined conditions through identification of regulatory factors 0.54
Formation control between leader and migratory follower tissues allows coordinated growth 0.37

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