Bioinformatics and Computational Biology articles for Germany

Time frame: 1 June 2025 - 30 May 2026

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Count: 291

Article ‘Count’ for Bioinformatics and Computational Biology.

Journal Count Share
3 1.89
The relationship between genotype- and phenotype-based estimates of genetic liability to psychiatric disorders, in practice and in theory 0.06
Exploring the omnigenic architecture of selected complex traits 1.00
Single-cell transcriptome-wide Mendelian randomization and colocalization analyses uncover cell-specific mechanisms in atherosclerotic cardiovascular disease 0.83
23 14.54
Determination from Nontargeted Metabolite Profiling Using Internal and External Standards 0.07
Best Practices in GC–MS and GC × GC–MS-Based Metabolomics and Volatile Analyses: An International Survey 0.08
Rapid Analysis of NAD and Other Phosphorylated Metabolites in Complex Biological Samples by Hydrophilic Interaction Liquid Chromatography Coupled with Tandem Mass Spectrometry 0.08
A Prototype timsOmni Platform Enables Confident Annotation of the Key Hypervariable CDR3 Regions of IgG Immunoglobulins Using Low- and High-Energy Electron-Based Fragmentation 0.23
Integrated Single-Cell Mass Spectrometry Imaging and Immunofluorescence Microscopy for Multimodal Characterization of Human Immune Cells 1.00
A Sugaromics Method for Combined Targeted and Untargeted Sugar Profiling: Fit-for-Purpose Validation of a Quantitative GC × GC-MS Approach 1.00
Intrinsic N-Terminal Reactivity and Improved Analysis of DSSO-Carbamate and Carbamate-Based Cross-Linkers 0.28
Pho-Tip: One-Pot Dephosphorylation for Rapid and Sensitive Analysis of DIA Phosphoproteomics Data 1.00
Coupling Liquid Chromatography to Orbitrap Isotope Ratio Mass Spectrometry: Overcoming Isotope Effects of Chromatography and Amount-Dependency by Peak Homogenization 0.83
xcms in Peak Form: Now Anchoring a Complete Metabolomics Data Preprocessing and Analysis Software Ecosystem 0.41
Not One Method to Rule Them All: A Comparative Study of Chromatographic Platforms (RP-LC-, HILIC-, SFC-, and IC-HRMS) for Water Analysis 0.38
Trapped Ion Mobility Improves Annotation Accuracy in LC-HRMS Screening Applications for Exposomics 1.00
prm-PASEF-Based Quantification and Isomeric Model for Extended Coverage of Human Plasma Lipidome in Parkinson’s Disease 0.86
High-Frequency Microfluidic Fractionation for Compound-Resolved Bioactivity-Based Metabolomics 0.82
Selective Comprehensive Online NanoLCxCZE-MS Platform for Top-Down Proteoform Analysis 1.00
UCL-MetIsoLib: A Public High-Resolution Tandem Mass Spectrometry Library for HILIC-Based Isomer-Resolved Profiling of Glycolysis, Central Carbon Metabolism, and Beyond in Urine, Plasma, Tissues, Cells, and Patient-Derived Organoids 0.08
AIRPred: A Deep Learning Model Predictor for Peptide Intensity Ratios in Cross-Linking Mass Spectrometry Improves Cross-Link Spectrum Matching 1.00
Determination of Methyl Group Positions in Long-Chain Aliphatic Methyl Ethers and Alcohols by Gas Chromatography/Orbitrap Mass Spectrometry 1.00
Development of a Robust Platform for Infrared Ion Spectroscopy: A New Addition to the Analytical Toolkit for Enhanced Metabolite Structure Elucidation 0.13
Quantification of Arginine-Rich Cyclic Cell-Penetrating Peptide–Lipid Conjugates Using a Surrogate Peptide Extracted by Phospholipase D Digestion and Trifluoroacetic Acid-Based UPLC-MS/MS Analysis 1.00
Identification of Isomeric Metabolites Using Cold Ion Spectroscopy Add-on to Orbitrap-Based Mass Spectrometer 0.33
Multicolumn Two-Dimensional Liquid Chromatography Screening Platform for Stereopeptidomics and Application to Antimicrobial Peptide Polyene and Lipopeptide 1.00
Integrative Analysis of Nontargeted LC-HRMS and High-Throughput Metabarcoding Data for Aquatic Environmental Studies Using Combined Multivariate Statistical Approaches 0.96
4 2.30
Intact Proteoform Analysis by Capillary Electrophoresis–Mass Spectrometry. Are We There Yet? 0.09
Optimized In‐Solution and Gas‐Phase Chemistry Enables High‐Efficiency Interactome Mapping by DSBSO‐Based Cross‐Linking Mass Spectrometry 0.86
Bifunctional Probes Reveal the Rules of Intracellular Ether Lipid Transport 0.86
LC‐MS and High‐Throughput Data Processing Solutions for Lipid Metabolic Tracing Using Bioorthogonal Click Chemistry 0.50
1 0.93
Spatially informed phenotyping by cyclic-in-situ-hybridisation identifies novel fibroblast populations and their pathogenic niches in systemic sclerosis 0.93
1 0.05
Distinct effects of complement C4A and C4B copy number in Systemic Sclerosis serological and clinical subtypes 0.05
2 0.14
IPSS-M risk and specific sex-associated somatic mutations predict response to ESA therapy in LR-MDS: building a new score 0.11
Array Genotyping of Transfusion Relevant Blood Cell Antigens in 6946 Ancestrally Diverse Subjects 0.03
1 0.99
Repeat-associated ataxias in a German patient cohort analysed by targeted parallel long-read sequencing 0.99
5 0.28
IGSF11-VISTA is a critical and targetable immune checkpoint axis in diffuse midline glioma 0.02
Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma 0.06
Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer 0.11
The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets 0.02
Gene context drift identifies drug targets to mitigate cancer treatment resistance 0.07
1 1.00
Integrative Multiomics and Drug Sensitivity Profiling Reveal Potential Biomarkers and Therapeutic Strategies in Pediatric Solid Tumors 1.00
10 3.19
RegVelo: Gene-regulatory-informed dynamics of single cells 0.41
Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome 0.15
Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles 0.02
Complete biosynthesis of nicotine 0.09
Large-scale proteomics across neurological disorders uncovers biomarker panel and targets in multiple sclerosis 0.87
BRAIN-MAGNET: A functional genomics atlas for interpretation of non-coding variants 0.18
Genome sequences of extant and extinct gibbons reveal their phylogeny, demographic history, and conservation status 0.04
The genetic history of the Southern Caucasus from the Bronze Age to the Early Middle Ages: 5,000 years of genetic continuity despite high mobility 0.50
HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics 0.83
Denisovan mitochondrial DNA from dental calculus of the >146,000-year-old Harbin cranium 0.11
1 0.19
Genome and Transcriptome-Wide Analyses Identify Multiple Candidate Genes and a Significant Polygenic Contribution in Bicuspid Aortic Valve. 0.19
3 1.25
Robust termite phylogenies built using transposable element composition and insertion events 0.30
An early East Asian lineage with unexpectedly low Denisovan ancestry 0.79
A new Cambrian stem-group echinoderm reveals the evolution of the anteroposterior axis 0.17
1 0.90
Integrative Metabolomics of Targeted and Non-Targeted Analyses in T2D Progression. 0.90
1 0.18
Unveiling Redox-Active Quinones in Pyrogenic Carbon by Nontargeted Metabolomics and Dual Chemical Tagging 0.18
2 0.74
Genetic determinants of childhood blood pressure and heart rate in relation to adult health outcomes: the consortium of childhood blood pressure 0.03
Clonal haematopoiesis of indeterminate potential and mortality in coronary artery disease 0.70
1 0.74
Temporal loss of En1 during limb development causes distinct phenotypes 0.74
8 3.46
Single-cell template strand sequencing reveals culture-induced chromosomal instability in a gibbon cell line 0.19
Robust and efficient annotation of cell states through gene signature scoring 0.13
A systems view on DNA damage response kinetics in Tetrahymena 0.86
Integration of high-throughput proteomic data and complementary omics layers with PriOmics 1.00
BayesRVAT enhances rare-variant association testing through Bayesian aggregation of functional annotations 0.63
Optimal marker genes for c-separated cell types with SepSolve 0.29
Pangenome-based genome inference using integer programming 0.33
Highly accurate assembly polishing with DeepPolisher 0.03
1 0.13
Chromatin-mediated anticipatory control of type I interferon production in plasmacytoid dendritic cells 0.13
1 1.00
Nucleosome linker DNA methylation by DNMT3A/DNMT3B3 is controlled by nucleosome binding and multimerization of DNMT3 complexes on DNA 1.00
1 0.16
Molecular-Based Ecosystem to Improve Personalized Medicine in Chronic Myelomonocytic Leukemia. 0.16
1 0.71
Bifunctional Lipid–Protein Cross-linking Efficiency and Reaction Products 0.71
1 0.40
Root cause discovery via permutations and Cholesky decomposition 0.40
4 1.94
Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stability 0.22
Cryo-EM reveals open and closed Asgard chromatin assemblies 0.67
A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation 0.05
Chip (Ldb1) is a putative cofactor of Zelda forming a functional bridge to CBP during zygotic genome activation 1.00
3 0.54
Identifying genetic contributions of 6q21 loci and PPAR pathway to antipsychotic-induced metabolic syndrome: a Sex-Stratified Multi-Omics study 0.04
Within- and between-family genetic effects on educational achievement vary across countries and ages 0.40
Leveraging transdiagnostic genetic liability to psychiatric disorders to dissect clinical outcomes of anorexia nervosa 0.11
18 3.98
The evolutionary history and unique genetic diversity of Indigenous Americans 0.10
Chromosomal fusions trigger rediploidization of autopolyploid genomes 0.01
Ancient DNA reveals pervasive directional selection across West Eurasia 0.03
Saturation editing of reveals distinct dominant and recessive disorders 0.05
A disease model resource reveals core principles of tissue-specific cancer evolution 0.73
Lasting Lower Rhine–Meuse forager ancestry shaped Bell Beaker expansion 0.05
An integrated view of the structure and function of the human 4D nucleome 0.09
Mapping the genetic landscape across 14 psychiatric disorders 0.11
Eight millennia of continuity of a previously unknown lineage in Argentina 0.03
A haplotype-based evolutionary history of barley domestication 0.44
Whole-genome sequencing of 490,640 UK Biobank participants 0.01
Mouse lemur cell atlas informs primate genes, physiology and disease 0.01
A molecular cell atlas of mouse lemur, an emerging model primate 0.01
Complex genetic variation in nearly complete human genomes 0.20
Structural variation in 1,019 diverse humans based on long-read sequencing 0.60
Pathology-oriented multiplexing enables integrative disease mapping 0.72
Ongoing genome doubling shapes evolvability and immunity in ovarian cancer 0.04
A haplotype-resolved pangenome of the barley wild relative 0.77
2 1.91
AlphaDIA enables DIA transfer learning for feature-free proteomics 0.91
Shortcomings of silhouette in single-cell integration benchmarking 1.00
5 2.00
Visualizing suborganellar lipid distribution using correlative light and electron microscopy 0.73
LBR and LAP2 mediate heterochromatin tethering to the nuclear periphery to preserve genome homeostasis 0.04
Two distinct chromatin modules regulate proinflammatory gene expression 0.86
Lineage-determining transcription factors constrain cohesin to drive multi-enhancer oncogene regulation 0.10
RNA-binding proteins mediate the maturation of chromatin topology during differentiation 0.27
90 44.16
Genomic insights into the improvement of Chinese fir from ancient domestication continuum to modern breeding 0.02
Large-scale analysis of temporal gene expression variation in peripheral blood 0.35
GWAS of extended prescription analgesic use identifies genetic loci in chronic pain 0.05
Integrated genomic analyses identify oncogenic pathway interplay in hepatocarcinogenesis defining specific molecular subtypes 0.13
Critical evaluation of drug response prediction models with DrEval 1.00
Continental-scale genomic surveillance of Plasmodium falciparum malaria across sub-Saharan Africa with rapid nanopore sequencing 0.27
Genome reshaping by Helitron transposons in Fusarium oxysporum TR4 affects secondary metabolism but not virulence 0.04
Population-based genome-wide association study of plasma complex lipid species 1.00
Multiomics immune profiling of a patient-relevant orthotopic lung cancer model using SEPARATE-Seq 0.04
Horizontal gene transfer and diploidy illuminate evolution and stress adaptation in oleaginous Scenedesmaceae (Chlorophyta) 0.22
Population differences of chromosome 22q11.2 duplication structure predispose differentially to microdeletion and inversion 0.04
Comparison and optimization of cellular neighbor preference methods for quantitative tissue analysis 0.95
The adaptive molecular landscape of reprogrammed telomeric sequences 0.14
Genetic architecture of lumbar spinal stenosis 0.01
Experimental assessment of AI-based interactome mapping 0.01
Dnmt1 mediates epigenetic restriction of invasive traits in clonal crayfish 1.00
Solubility based mechanistic profiling of combinatorial drug therapy 0.08
Transcriptional competence defines the heterochromatin nucleating potential of isolated MSR units 0.78
A blueprint for local and distal invasion programs in glioblastoma 0.02
An international multi-centre study to develop and validate federated learning-based prognostic models for anal cancer 0.09
Regionalized regulation of actomyosin organization influences cardiomyocyte cell shape changes during chamber curvature formation 0.40
Cell type-specific epigenetic regulatory circuitry of coronary artery disease loci 0.90
Mechanisms of gene regulation by SRCAP and H2A.Z 0.63
Benchmarking EGF signaling pathway inference using phosphoproteomics and kinase-substrate interactions 0.93
High-throughput chemical proteomics workflow for profiling protein citrullination dynamics 0.91
Tumor cell villages define the co-dependency of tumor and microenvironment in liver cancer 0.20
Extrusion fountains are hallmarks of chromosome organization emerging upon zygotic genome activation 0.33
KidneyGenAfrica multi-cohort Genome-wide association study and polygenic prediction of kidney function in 110,000 Africans 0.09
High-throughput multi-organ proteomics workflow for drug efficacy and toxicity analysis 0.11
Adgrg6/Gpr126 is required for compact wall integrity and establishing trabecular identity during cardiac trabeculation 0.90
Cross ionization mode chemical similarity prediction between tandem mass spectra in metabolomics 0.50
An experimentally-informed polymer model reveals high resolution organization of genomic loci 0.50
Crowdsourced biodiversity monitoring fills gaps in global plant trait mapping 0.25
An adaptive, continuous-learning framework for clinical decision-making from proteome-wide biofluid data 0.81
Community benchmarking and evaluation of human unannotated microprotein detection by mass spectrometry based proteomics 0.06
The Knowledge Connector decision support system for multiomics-based precision oncology 1.00
The Camellia sinensis var. sinensis cv. Fuding Dabaicha genome unveils structural variation-driven metabolic innovation 0.40
Pulsed evolution shaped extant angiosperm pollen disparity 0.06
Prostate cancer cells converge to an inflammatory-like state upon metastatic dissemination 0.47
Structure of the Methanosarcina mazei Mtr complex bound to the oxygen-stress responsive small protein MtrI 1.00
Cross-platform clinical proteomics using the Charité open standard for plasma proteomics (OSPP) 0.93
Chromosome-level haplotype-resolved assembly of highly heterozygous grass genomes with PhaseGrass 0.43
Recombination junctions from antibody isotype switching classify immune and DNA repair dysfunction 0.86
Complex genetic effects linked to plasma protein abundance in the UK Biobank 0.03
Evaluating transportability of in vitro cellular models to in vivo human phenotypes using gene perturbation data 0.08
RoCK and ROI: single-cell transcriptomics with multiplexed enrichment of selected transcripts and region-specific sequencing 0.29
Repurposing clinically safe drugs for DNA repair pathway choice in CRISPR genome editing and synthetic lethality 1.00
Acquisition of ampliconic sequences marks a selfish mouse -haplotype 0.67
Recessive variants in the intergenic locus cause monogenic kidney disease responsive to anti-proteinuric treatment 0.15
Long-read sequencing of primate testis and human sperm allows identification of recombination events in individuals 0.13
Domestication shaped the chromatin landscape of grain amaranth 0.75
Multi-centric origins and gene flow shape the diversity of β-thalassemia mutations in Southern East Asia 0.03
Differential conformational expansion of NUP98-HOXA9 oncoprotein from nanosized assemblies to macrophases 1.00
AI-powered spatial cell phenomics enhances risk stratification in non-small cell lung cancer 0.99
Powerful one-dimensional scan to detect heterotic quantitative trait loci 1.00
Endothelial RNF20 suppresses endothelial-to-mesenchymal transition and safeguards physiological angiocrine signaling to prevent congenital heart disease 0.95
HSP90 as an evolutionary capacitor drives adaptive eye size reduction via atonal 1.00
Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations 0.01
The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities 0.11
Conformational plasticity of disordered regions enables sequence-diverse DNA recognition by transcription factor AflR 0.08
Benchmarking scRNA-seq copy number variation callers 0.67
Multicenter evaluation of label-free quantification in human plasma on a high dynamic range benchmark set 1.00
Trans-eQTL mapping prioritises USP18 as a negative regulator of interferon response at a lupus risk locus 0.13
TP53 variant clusters stratify phenotypic diversity in germline carriers and reveal an osteosarcoma-prone subgroup 0.08
RAPDOR: Using Jensen-Shannon Distance for the computational analysis of complex proteomics datasets 1.00
Graph neural networks learn emergent tissue properties from spatial molecular profiles 0.93
The genetic diversity of Indonesian cattle has been shaped by multiple introductions and adaptive introgression 0.02
TEtrimmer: a tool to automate the manual curation of transposable elements 0.60
A mesothelial differentiation gateway drives fibrosis 0.93
: AI generation of multiplex immunofluorescence staining from histopathology images 0.12
Unveiling genetic signatures of immune response in immune-related diseases through single-cell eQTL analysis across diverse conditions 0.66
High performance data integration for large-scale analyses of incomplete profiles using Batch-Effect Reduction Trees (BERT) 1.00
vPro-MS enables identification of human-pathogenic viruses from patient samples by untargeted proteomics 1.00
DynaTag for efficient mapping of transcription factors in low-input samples and at single-cell resolution 0.90
Enhancing tandem mass spectrometry-based metabolite annotation with online chemical labeling 0.67
Machine learning in Alzheimer’s disease genetics 0.11
Nanoscale 3D DNA tracing in non-denatured cells resolves the Cohesin-dependent loop architecture of the genome in situ 0.55
Single nucleosome imaging reveals principles of transient multiscale chromatin reorganization triggered by histone ADP-ribosylation at DNA lesions 0.08
Ultra-sensitive metaproteomics redefines the dark metaproteome, uncovering host-microbiome interactions and drug targets in intestinal diseases 0.43
Forced expression of MSR repeat transcripts above a threshold limit breaks heterochromatin organisation 1.00
Resolving out of Africa event for Papua New Guinean population using neural network 0.07
In silico genomic surveillance by CoVerage predicts and characterizes SARS-CoV-2 variants of interest 1.00
MR-link-2: pleiotropy robust Mendelian randomization validated in three independent reference datasets of causality 0.13
Shared genetic architecture of posttraumatic stress disorder with cardiovascular imaging, risk, and diagnoses 0.02
Charting γ-secretase substrates by explainable AI 0.83
Prosit-XL: enhanced cross-linked peptide identification by fragment intensity prediction to study protein interactions and structures 0.96
A genome-wide association study in 10,000 individuals links plasma N-glycome to liver disease and anti-inflammatory proteins 0.06
ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution 0.97
Maximizing meiotic crossover rates reveals the map of Crossover Potential 1.00
A versatile information retrieval framework for evaluating profile strength and similarity 0.08
23 7.00
Histone acetylation-dependent clustering of BRD2 instructs transcription dynamics 1.00
Exome sequencing and analysis of 44,028 British South Asians enriched for high autozygosity 0.01
Pan-cancer inference and validation of hypermorphic, hypomorphic and neomorphic mutations 0.29
A microenvironment-determined risk continuum refines subtyping in meningioma and reveals determinants of machine learning-based tumor classification 0.76
Linking the plasma proteome to genetics in individuals from continental Africa provides insights into type 2 diabetes pathogenesis 0.63
Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction 0.11
Multitrait analyses identify genetic variants associated with aortic valve function and aortic stenosis risk 0.03
Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models 0.60
Uniform dynamics of cohesin-mediated loop extrusion in living human cells 0.07
Spatiotemporal gene expression and cellular dynamics of the developing human heart 0.03
Complete genome assemblies of two mouse subspecies reveal structural diversity of telomeres and centromeres 0.03
Locityper enables targeted genotyping of complex polymorphic genes 0.67
Nucleotide dependency analysis of genomic language models detects functional elements 0.88
A genetic map of human metabolism across the allele frequency spectrum 0.64
Limited overlap between genetic effects on disease susceptibility and disease survival 0.03
Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes 0.02
DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution 0.01
A comparison of 27 Arabidopsis thaliana genomes and the path toward an unbiased characterization of genetic polymorphism 0.48
Genetic variation at transcription factor binding sites largely explains phenotypic heritability in maize 0.42
Analysis of individual patient pathway coordination in a cross-species single-cell kidney atlas 0.01
Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy 0.02
Detecting and quantifying clonal selection in somatic stem cells 0.17
Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations 0.09
3 0.49
Genetic and molecular landscape of comorbidities in people living with HIV 0.33
Polygenic prediction of body mass index and obesity through the life course and across ancestries 0.08
Real-world deployment of a fine-tuned pathology foundation model for lung cancer biomarker detection 0.08
17 9.36
Decoding sequence determinants of gene expression in diverse cellular and disease states 0.04
Differentiation of sphingomyelin and cholesterol by hyperspectral mid-infrared detection of single-bond vibrational modes in the fingerprint region 0.96
SNP calling, haplotype phasing and allele-specific analysis with long RNA-seq reads 0.03
Integration of alternative fragmentation techniques into standard LC-MS workflows using a single deep learning model enhances proteome coverage 0.33
Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny 0.29
Pertpy: an end-to-end framework for perturbation analysis 0.84
Inferring cell differentiation maps from lineage tracing data 0.13
C-COMPASS: a user-friendly neural network tool profiles cell compartments at protein and lipid levels 0.85
Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model 0.98
Nicheformer: a foundation model for single-cell and spatial omics 1.00
Annotating the genome at single-nucleotide resolution with DNA foundation models 0.33
PHLOWER leverages single-cell multimodal data to infer complex, multi-branching cell differentiation trajectories 0.90
scooby: modeling multimodal genomic profiles from DNA sequence at single-cell resolution 0.71
MSnLib: efficient generation of open multi-stage fragmentation mass spectral libraries 0.08
Functional phenotyping of genomic variants using joint multiomic single-cell DNA–RNA sequencing 0.80
Morphological map of under- and overexpression of genes in human cells 0.11
Deep-learning-based gene perturbation effect prediction does not yet outperform simple linear baselines 1.00
2 0.40
Spatial proteomic analysis in human Alzheimer’s disease brains enables identification of microenvironment-dependent microglial cell states 0.26
Fine-mapping genomic loci refines bipolar disorder risk genes 0.14
3 1.44
Integrated MINFLUX tracking reveals two distinct chromatin dynamics classes across cell types 0.17
Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs 0.28
Reporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus 1.00
2 1.13
Human brain vascular multi-omics elucidates disease-risk associations 0.13
Epigenome profiling identifies H3K27me3 regulation of extracellular matrix composition in human corticogenesis 1.00
2 0.81
The complex evolution and genomic dynamics of mating-type loci in Cryptococcus and Kwoniella 0.10
Systematic screen uncovers regulator contributions to chemical cues in Escherichia coli 0.71
6 1.66
Epigenetic gene regulation is controlled by distinct regulatory complexes utilizing specialized paralogs of TELOMERE REPEAT BINDING FACTORS 1.00
Simplifying causal gene identification in GWAS loci 0.27
Genetic underpinnings of chills from art and music 0.13
Pathway polygenic risk scores (pPRS) for the analysis of gene-environment interaction. 0.05
Bayesian network imputation methods applied to multi-omics data identify putative causal relationships in a type 2 diabetes dataset containing incomplete data: An IMI DIRECT Study. 0.14
Sodium azide mutagenesis induces a unique pattern of mutations 0.08
1 1.00
Breaking down data silos across companies to train genome-wide predictions: A feasibility study in wheat 1.00
14 6.25
Sperm, egg, and embryo proteins critical for genetic adaptation of herring to low salinity in the Baltic Sea 0.41
A universal polymer signature in Hi-C resolves cohesin loop density and supports monomeric extrusion 0.25
Coalescence and translation: A language model for population genetics 0.40
Detecting gene–environment interactions to guide personalized intervention: Boosting distributional regression for polygenic scores 1.00
Convergent evolution increases boron transport through SNPs and tandem duplications at BOR1 and BOR2 in Arabidopsis thaliana 0.58
Archaeogenetic insights into the demographic history of Late Neanderthals 0.59
A high-coverage Neandertal genome from the Altai Mountains reveals population structure among Neandertals 0.55
Functional motifs in food webs and networks 0.50
Sudan’s complex genetic admixture history drives adaptation to malaria in Sudanese Copts 0.06
Deep evolutionary conservation of a sex-determining locus without sequence homology 0.67
Uncovering heterogeneous intercommunity disease transmission from neutral allele frequency time series 0.13
Single-cell metabolome and RNA-seq multiplexing on single plant cells 1.00
Genome analyses suggest recent speciation and postglacial isolation in the Norwegian lemming 0.05
The importance of small-island populations for the long-term survival of endangered large-bodied insular mammals 0.06
2 0.40
Extinct Dalian horse as a genetic bridge between Late Pleistocene North American and Eurasian equids 0.06
Virtual endocast of the Late Miocene Hoplitomeryx matthei (Artiodactyla, Hoplitomerycidae) and brain evolution in insular ruminants. 0.33
7 1.53
Mechanical load inhibits cancer growth in mouse and human hearts 0.03
The evolution of gene regulation in mammalian cerebellum development 0.72
Multiscale structure of chromatin condensates explains phase separation and material properties 0.05
A genome-to-proteome map reveals how natural variants drive proteome diversity and shape fitness 0.50
<atl>Genomic diversity of the African malaria vector iAnopheles funestus/i</atl> 0.01
Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics 0.17
Origins and diversity of Greenland’s Qimmit revealed with genomes of ancient and modern sled dogs 0.05
7 1.97
Stage-specific epigenetic priming amplifies gene activation during lineage commitment 1.00
Integrative analysis of mRNA stability regulation uncovers a metastasis-suppressive program in breast cancer 0.03
The bottleneck for maternal transmission of mtDNA is linked to purifying selection by autophagy 0.07
Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier 0.02
Soma-derived 30-nt small RNAs are coupled with chromosome breakage and precisely target nontransposon DNA against elimination in Euplotes vannus 0.14
Indirect genetic effects among neighbors promote cooperation and accelerate adaptation in a small-scale human society 0.10
Genomic evidence for fisheries-induced evolution in Eastern Baltic cod 0.62
2 0.44
Direct visualization and tracing of chromatin folding in the Drosophila embryo 0.36
Epromoters bind key stress-related transcription factors to regulate clusters of stress response genes 0.08
2 1.30
Strain-level diversity of giant viruses infecting chlorarachniophyte algae in the subtropical North Pacific 0.65
Redox gradients define the ecological niche of ciliates with denitrifying endosymbionts in anoxic lake waters 0.65
1 0.36
Machine learning-assisted diagnosis classification of primary immune dysregulation using IDDA2.1 phenotype profiling 0.36
2 0.86
Gene and genome duplications have contrasting impacts on biosynthetic and flower developmental pathways in California poppy 0.36
Reactivation of the tRNASer/tRNATyr gene cluster in Arabidopsis thaliana root tips 0.50

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