Bioinformatics and Computational Biology articles for Japan

Time frame: 1 June 2025 - 30 May 2026

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Count: 104

Article ‘Count’ for Bioinformatics and Computational Biology.

Journal Count Share
1 0.45
Novel Genetic Loci for Nontuberculous Mycobacterial Pulmonary Disease and Potential Protective Effect of Body Mass Index. 0.45
6 4.13
A Reproducible Multichannel Synchronous Rapid Phosphopeptide Enrichment Strategy Enabled by Anisotropic Porous Chitosan-Based Arrays 0.11
Resolving sn-Positional Isomers of Docosahexaenoic Acid-Bound Phospholipids in the Mouse Brain by Cyclic Ion Mobility Mass Spectrometry Imaging 1.00
Deep-Learning Prediction of Protein Secondary Structure from Circular Dichroism Spectrum Using Three-Layer Image Recognition 0.86
CRB-FCC: A Standardized Nontargeted Analysis for Formula Assignment and Structure Annotation 0.17
Development of a Real-Time Monitoring System for the Adherent Human Keratinocyte Metabolism by Live-Cell Metabolic NMR with Illumination 1.00
Toward the Development of a Novel Newborn Screening Modality: In-Depth Nontargeted Proteome Analysis of Dried Blood Spots with a Robotic Pipeline Using Low-Cost Iron Powders 1.00
1 0.59
Blood Lactate as a Prognostic Biomarker for Survival and Weight Loss in Amyotrophic Lateral Sclerosis: An Exploratory–Validation Study 0.59
1 0.06
Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma 0.06
3 0.20
Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles 0.00
Whole-body molecular and cellular mapping of the laboratory mouse 0.18
CLIM-TIME identifies metastatic microenvironment modulators for T cell therapy response 0.01
1 0.39
Obesity- and Lipid-Related Traits May Causally Contribute to Sepsis-Associated Acute Kidney Injury. 0.39
3 0.75
Compound starch granule formation in grass seeds is associated with distinct temporal patterns of gene expression 0.25
Dispersal and isolation of the scaly-foot snail across abyssal insular habitats and through time 0.10
Robust termite phylogenies built using transposable element composition and insertion events 0.40
1 1.00
Endothelial-zippering proceeds by sensing heartbeat-driven force through cadherin-6 during heart-vessel connection in zebrafish 1.00
1 0.06
Genetic determinants of childhood blood pressure and heart rate in relation to adult health outcomes: the consortium of childhood blood pressure 0.06
3 1.55
H3K27 and H3K9 methylation mask potential CTCF binding sites to maintain 3D genome integrity 1.00
CGC1, a new reference genome for Caenorhabditis elegans 0.53
Highly accurate assembly polishing with DeepPolisher 0.02
1 1.00
Condensin II collaborates with cohesin to establish and maintain interphase chromosome territories 1.00
1 1.00
Subcellular Analysis of Fatty Acid Metabolism Using Organelle-Selective Click Chemistry 1.00
1 0.05
Transcription and cohesin direct domain boundary spatial positioning and are linked to Friedreich’s ataxia 0.05
2 1.01
Ethanolamine as a potential biomarker and therapeutic target for depressive disorder 1.00
Leveraging transdiagnostic genetic liability to psychiatric disorders to dissect clinical outcomes of anorexia nervosa 0.01
1 0.58
Automated High-Throughput Raman Spectral Framework for Cellular Differentiation Monitoring 0.58
8 1.19
Functional dissection of complex trait variants at single-nucleotide resolution 0.04
A cross-population compendium of gene–environment interactions 1.00
Causal modelling of gene effects from regulators to programs to traits 0.05
Specificity, length and luck drive gene rankings in association studies 0.06
Clone copy number diversity is linked to survival in lung cancer 0.02
A molecular cell atlas of mouse lemur, an emerging model primate 0.01
Mouse lemur cell atlas informs primate genes, physiology and disease 0.01
Pathology-oriented multiplexing enables integrative disease mapping 0.02
1 0.04
CoCo-ST detects global and local biological structures in spatial transcriptomics datasets 0.04
29 11.97
Multi-ancestry transcriptome-wide association studies uncover insights into breast cancer genetics and biology 0.10
Population-scale chemical response revealed by a barcoded yeast collection 0.36
Accessing medically relevant complex regions with a pangenome graph of 20 near-complete Japanese haplotypes 0.56
qChIP-MS reveals the local chromatin composition by label-free quantitative proteomics 0.02
Bridging sequence-structure motifs and genetic variants for genome-wide dynamic RNA-protein interaction profiling 0.10
Interpretable modality-aware mapping of gene regulation in single-cell multiomics with scMAGCA 0.11
Distinct roles of MCM2-7 subunits in replication licensing in human cells 0.06
Multi-trait polygenic risk scores improve genomic prediction of atrial fibrillation across diverse ancestries 0.74
Widespread gene-environment interactions shape the immune response to SARS-CoV-2 infection in hospitalized COVID-19 patients 0.03
Population differences of chromosome 22q11.2 duplication structure predispose differentially to microdeletion and inversion 0.02
MYC modulates TOP2A diffusion to promote substrate detection and activity 0.06
The ratio of circulatory levels of sphingolipids to steroids predicts asthma exacerbations 0.04
Robust characterization and interpretation of rare pathogenic cell populations from spatial omics using GARDEN 0.10
Mixed-model and transcriptome-wide association analyses identify transcription factors and genes associated with colorectal cancer susceptibility 0.09
A scalable two-step genome editing strategy for generating full-length gene-humanized mice at diverse genomic loci 1.00
Simultaneous epigenomic profiling and regulatory activity measurement using e2MPRA 0.45
Reconstructing epigenomic dynamics through a single-cell multi-epigenome data integration framework 1.00
scRepli-RamDA-seq: a multi-omics technology enabling the analysis of gene expression dynamics during S-phase 1.00
Enabling whole genome sequencing analysis from FFPE specimens in clinical oncology 0.04
Comparative transcriptome atlas as an assistive modality for complex classification of rare kidney cancers 0.89
Mechanistic models of asymmetric hand-over-hand translocation and nucleosome navigation by CMG helicase 1.00
Condensation-dependent interactome of a chromatin remodeler underlies tumor suppressor activities 1.00
The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities 0.07
Trans-eQTL mapping prioritises USP18 as a negative regulator of interferon response at a lupus risk locus 0.04
Giant extrachromosomal element “Inocle” potentially expands the adaptive capacity of the human oral microbiome 0.94
Quantitative phase imaging with temporal kinetics predicts hematopoietic stem cell diversity 0.95
Machine learning-assisted decoding of temporal transcriptional dynamics via fluorescent timer 0.90
Charting γ-secretase substrates by explainable AI 0.17
Faster adaptation but slower divergence of X chromosomes under paternal genome elimination 0.14
11 1.41
H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs 0.01
Empirically determined baseline masking strategies and other considerations for gene-level burden tests 0.01
GGC repeat expansions within new open reading frames are translated into toxic polyglycine proteins in oculopharyngodistal myopathy 0.08
MultiSuSiE improves multi-ancestry fine-mapping in All of Us whole-genome sequencing data 0.04
Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction 0.04
Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models 0.06
Disentangling the architectural and non-architectural functions of CTCF and cohesin in gene regulation 0.07
Complete genome assemblies of two mouse subspecies reveal structural diversity of telomeres and centromeres 0.08
Genetic variation at transcription factor binding sites largely explains phenotypic heritability in maize 0.01
Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution 1.00
Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations 0.01
5 1.92
Genetic regulation across germline and somatic variation on the Y chromosome contributes to type 2 diabetes 0.85
Real-world clinical utility of comprehensive genomic profiling in advanced solid tumors 1.00
The proteogenomic landscape of the human kidney and implications for cardio-kidney-metabolic health 0.01
Polygenic prediction of body mass index and obesity through the life course and across ancestries 0.03
Deep phenotyping of health–disease continuum in the Human Phenotype Project 0.03
1 0.02
SNP calling, haplotype phasing and allele-specific analysis with long RNA-seq reads 0.02
2 0.08
Trans-ancestry genome-wide analyses of bipolar disorder in East Asian and European populations improve genetic discovery 0.05
Fine-mapping genomic loci refines bipolar disorder risk genes 0.03
1 0.67
The mitotic STAG3–cohesin complex shapes male germline nucleome 0.67
3 0.31
Neural signaling contributes to heart formation and growth in the invertebrate chordate, Ciona robusta 0.18
DRfold2 is a deep learning-based tool that enables efficient and accurate RNA structure prediction 0.08
Dual transcriptional activities of PAX3 and PAX7 spatially encode spinal cell fates through distinct gene networks 0.04
1 0.22
Unraveling the genetic links between stature and disease in East Asians: A multi-biobank genetic correlation and risk prediction study 0.22
1 0.06
Pangenome Analysis Reveals Structural Variations Associated With Citric Acid Accumulation in Prunus mume 0.06
7 2.01
Sperm, egg, and embryo proteins critical for genetic adaptation of herring to low salinity in the Baltic Sea 0.18
Orthogonal disentanglement of single-cell multi-omics reveals private and shared drivers of tissue development and pathogenesis 0.07
Extracellular stiffness regulates cell fate determination and drives the emergence of evolutionary novelty in the teleost heart 1.00
Genomes of the Golden Horde elites and their implications for the rulers of the Mongol Empire 0.33
HLA-DQB1*03:01 strongly affects age of onset of type 1 narcolepsy independently of DQA1 and ethnicity 0.17
Uncovering heterogeneous intercommunity disease transmission from neutral allele frequency time series 0.17
Deep origins, distinct adaptations, and species-level status indicated for a glacial relict seal 0.10
1 0.02
The evolution of gene regulation in mammalian cerebellum development 0.02
5 4.38
Linker histone H1 functions as a liquid-like glue to organize chromatin in living human cells 0.50
Decoding the molecular logic of rapidly evolving ZAD zinc finger proteins in Drosophila 0.88
Mass extinction triggered the early radiations of jawed vertebrates and their jawless relatives (gnathostomes) 1.00
Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture 1.00
Lubiprostone in chronic kidney disease: Insights into mitochondrial function and polyamines from a randomized phase 2 clinical trial 1.00
1 0.09
Gene and genome duplications have contrasting impacts on biosynthetic and flower developmental pathways in California poppy 0.09

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