Bioinformatics and Computational Biology articles for University of Michigan (U-M), United States of America (USA)

Time frame: 1 June 2025 - 30 May 2026

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Count: 89

Article ‘Count’ for Bioinformatics and Computational Biology.

Journal Count Share
1 0.98
Chromato-Kinetic Fingerprinting Enables Multiomic Digital Counting of Single Disease Biomarker Molecules 0.98
9 3.78
MetaGLIMPSE: Meta-imputation of low-coverage sequencing data for modern and ancient genomes 0.67
Mind the gap: Characterizing bias due to population mismatch in two-sample Mendelian randomization 1.00
Multiple-testing corrections in case-control studies using identity-by-descent segments 0.10
Logica: A likelihood framework for cross-ancestry local genetic correlation estimation using summary statistics 0.33
Multiple-testing corrections in selection scans using identity-by-descent segments 0.33
Skeletal muscle eQTL meta-analysis implicates genes in the genetic architecture of muscular and cardiometabolic traits 0.30
Genetic architecture and analysis practices of circulating metabolites in the NHLBI Trans-Omics for Precision Medicine Program 0.06
Rare-variant association studies: When are aggregation tests more powerful than single-variant tests? 0.78
Efficient Mendelian randomization analysis with self-adaptive determination of sample structure and multiple pleiotropic effects 0.22
1 0.14
Cross-Species Functional Genomic Screens Identify Novel Therapeutic Targets in Malignant Peripheral Nerve Sheath Tumors 0.14
2 2.00
Improving the Detection of Analyte Degeneracies in Untargeted Liquid Chromatography-Tandem Mass Spectrometry Data 1.00
High-Throughput Monoclonal Antibody Peptide Mapping Using 15-s HPLC Gradients Coupled with Cyclic Ion Mobility-Mass Spectrometry 1.00
1 1.00
Expanding High‐Fidelity Multiplexing in Ultrasensitive Single‐Molecule Protein Detection via Proximity Barcoding 1.00
1 0.05
Gain of function NOTCH4 variants disrupt angiogenesis in systemic sclerosis 0.05
1 0.15
Correlates and consequences of clonal hematopoiesis expansion rate: a 16-year longitudinal study of 6976 women 0.15
1 0.13
50,000 years of evolutionary history of India: Impact on health and disease variation 0.13
1 0.06
Genome and Transcriptome-Wide Analyses Identify Multiple Candidate Genes and a Significant Polygenic Contribution in Bicuspid Aortic Valve. 0.06
2 0.43
Linear covariation between germline and somatic mutation rates across ciliates and mammals 0.38
Population histories of the Indigenous Adivasi and Sinhalese from Sri Lanka using whole genomes 0.06
1 0.35
Plasma Metabolite Associations for Risk and Laboratory Measures of Type 2 Diabetes in a Large-Scale Finnish Prospective Cohort. 0.35
1 0.01
DNA/RNA-Based Next-Generation Sequencing Improves the Early Diagnosis and Management of Neoplastic Bile Duct Strictures: A 6-Year, Prospective, Multi-Institutional, Real-Time Study 0.01
1 0.11
Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits 0.11
1 1.00
Estimating causal effects of C-reactive protein on disease and health outcomes using multivariable Mendelian randomization adjusting for heritable confounding 1.00
2 0.83
Genome-wide variation in cell-free DNA end motif entropy predicts immunotherapy response in head and neck cancer 0.10
The hematopoietic stem cell MYB enhancer is essential and recurrently amplified during T-cell leukemogenesis 0.73
1 0.09
Multi-site DMS probing reveals higher-order structure of RNA-protein complexes in living cells 0.09
1 0.00
Leveraging transdiagnostic genetic liability to psychiatric disorders to dissect clinical outcomes of anorexia nervosa 0.00
7 0.20
Spatial atlas of diabetic kidney disease reveals a B cell-rich subgroup 0.02
Ancient DNA reveals pervasive directional selection across West Eurasia 0.06
An expanded registry of candidate -regulatory elements 0.02
An integrated view of the structure and function of the human 4D nucleome 0.02
Mapping the genetic landscape across 14 psychiatric disorders 0.00
Complex genetic variation in nearly complete human genomes 0.03
Pathology-oriented multiplexing enables integrative disease mapping 0.05
2 0.29
Sensitive detection of cancer antigens enabled by user-defined peptide libraries 0.04
Improving gene isoform quantification with miniQuant 0.25
27 6.05
Co-occurring clonal hematopoiesis exhibits strong selection and high leukemia risk 0.07
Admixture-informed polygenic risk reporting using the ePRS framework 0.12
Dynamic partitioning of a critical elongation factor between LEC and SEC regulates cellular snRNA and proliferation-related mRNA transcription 0.10
Early and late RNA eQTL are driven by different genetic mechanisms 0.05
Improving genomic prediction accuracy of complex traits by integrating massive types of functional annotation information 0.08
Multivariate genetic analysis reveals three distinct pathological dimensions in musculoskeletal disorders 0.11
An integrated germline and somatic genomic model for coronary artery disease 0.10
A blueprint for local and distal invasion programs in glioblastoma 0.26
mist: a hierarchical Bayesian framework for detecting differential DNA methylation dynamics in single-cell data 0.17
Analysis of isobaric quantitative proteomic data using TMT-Integrator and FragPipe computational platform 0.75
Genetic modifiers of -ε4-associated cognitive decline 0.01
Crowdsourced biodiversity monitoring fills gaps in global plant trait mapping 0.01
Improving polygenic score prediction for underrepresented groups through transfer learning 0.14
Cross-ancestry comparison of aptamer and antibody protein measures 0.02
Community benchmarking and evaluation of human unannotated microprotein detection by mass spectrometry based proteomics 0.03
FastCCC: a permutation-free framework for scalable, robust, and reference-based cell-cell communication analysis in single cell transcriptomics studies 0.33
Acquisition of ampliconic sequences marks a selfish mouse -haplotype 0.33
Integrating whole genome and transcriptome sequencing to characterize the genetic architecture of isoform variation 0.04
Inferring differential dynamics from multi-lineage, multi-omic, and multi-sample single-cell data with MultiVeloVAE 1.00
Gene expression signatures from whole blood predict amyotrophic lateral sclerosis case status and survival 0.80
Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations 0.12
The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities 0.03
Polygenic risk score for type 2 diabetes shows context-dependent effects across populations 0.02
: a web-based application for in-depth exploration of multi-omics data with brightfield histology 0.04
Causal mediation analysis for time-varying heritable risk factors with Mendelian randomization 0.75
Shared genetic architecture of posttraumatic stress disorder with cardiovascular imaging, risk, and diagnoses 0.01
DrFARM: identification of pleiotropic genetic variants in genome-wide association studies 0.57
3 1.17
Exome-wide association study of blood lipids in 1,158,017 individuals from diverse populations 0.01
Accelerated Bayesian inference of population size history from recombining sequence data 1.00
Genetic variants affecting RNA stability influence complex traits and disease risk 0.17
2 0.05
Circulating metabolites, genetics and lifestyle factors in relation to future risk of type 2 diabetes 0.02
Polygenic prediction of body mass index and obesity through the life course and across ancestries 0.03
3 0.27
Integration of alternative fragmentation techniques into standard LC-MS workflows using a single deep learning model enhances proteome coverage 0.22
Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny 0.00
cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions 0.05
2 0.07
CRISPRi screening in cultured human astrocytes uncovers distal enhancers controlling genes dysregulated in Alzheimer’s disease 0.05
Fine-mapping genomic loci refines bipolar disorder risk genes 0.02
1 0.03
Interplay between cohesin and RNA polymerase II in regulating chromatin interactions and gene transcription 0.03
1 0.08
Enhancer dynamics and cellular architecture in the human spinal cord 0.08
4 2.72
mFABIO: An integrative multi-tissue TWAS fine-mapping approach to prioritize potentially causal genes and tissues underlying binary traits 0.75
Functional interrogation of candidate cis-regulatory elements at the LDLR locus 1.00
Estimating the distribution of fitness effects of loss of heterozygosity (LOH) events using an engineered library of Saccharomyces cerevisiae 0.88
Genome-wide association study provides novel insight into the genetic architecture of severe obesity 0.09
5 3.49
Resolving competing evolutionary histories in joint ancestral state reconstruction 1.00
Mutation rate variability in viral populations: Implications for lethal mutagenesis 1.00
Proximity to explosive synchronization determines network collapse and recovery trajectories in neural and economic crises 0.55
Dynamic sensor selection for biomarker discovery 0.83
Inbreeding reduces fitness in spatially structured populations of a threatened rattlesnake 0.11
4 1.33
PSGRN: Gene regulatory network inference from single-cell perturbational data through self-training with synthetic gold standards 1.00
Introgressed mitochondrial fragments from archaic hominins alter nuclear genome function in modern humans 0.06
Circulating tumor cells as predictive biomarkers in the risk stratification of DCIS: Evidence of early dissemination 0.20
Integration of spatial protein imaging and transcriptomics in the human kidney tracks the regenerative potential of proximal tubules 0.07

Numerical information only (in the tables above) is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International.