Bioinformatics and Computational Biology articles for Yale University, United States of America (USA)

Time frame: 1 June 2025 - 30 May 2026

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Count: 85

Article ‘Count’ for Bioinformatics and Computational Biology.

Journal Count Share
4 2.27
Logica: A likelihood framework for cross-ancestry local genetic correlation estimation using summary statistics 0.33
A semi-empirical Bayes approach for calibrating weak instrumental bias in sex-specific Mendelian randomization studies 0.10
Knockoff procedure improves susceptibility gene identifications in conditional transcriptome-wide association studies 1.00
Leveraging local ancestry and cross-ancestry genetic architecture to improve genetic prediction of complex traits in admixed populations 0.83
1 0.04
Trend-Aligner: A Retention Time Modeling-Based Feature Alignment Method for Untargeted LC–MS Data Analysis 0.04
1 1.00
Polygenic Resistance to Blood Pressure Treatment and Stroke Risk: Insights from the All of Us Research Program 1.00
2 1.05
CLIM-TIME identifies metastatic microenvironment modulators for T cell therapy response 0.05
Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution 1.00
1 0.01
Genome and Transcriptome-Wide Analyses Identify Multiple Candidate Genes and a Significant Polygenic Contribution in Bicuspid Aortic Valve. 0.01
1 0.02
Epidemiologic and Bacterial Factors Facilitating Long-Term Transmission of Multidrug-Resistant Tuberculosis in Shanghai, China 0.02
1 0.40
Population genomics of a sailing siphonophore reveals genetic structure in the open ocean 0.40
1 0.01
DNA/RNA-Based Next-Generation Sequencing Improves the Early Diagnosis and Management of Neoplastic Bile Duct Strictures: A 6-Year, Prospective, Multi-Institutional, Real-Time Study 0.01
2 0.28
MYOD represses gene expression from non-E-box motifs 0.18
Restrictor slows RNAPII elongation to promote termination at noncoding RNA loci 0.10
6 2.15
Genealogy-based trait association with LOCATER boosts power at loci with allelic heterogeneity 0.24
spRefine denoises and imputes spatial transcriptomics with a reference-free framework powered by genomic language model 0.83
Stable genome structures in living fossil fishes 0.20
Chromosome engineering to correct a complex rearrangement on Chromosome 8 reveals the effects of 8p syndrome on gene expression and neural differentiation 0.56
A map of enhancer regions in primary human neural progenitor cells using capture STARR-seq 0.30
Highly accurate assembly polishing with DeepPolisher 0.02
1 0.03
The cell-type-specific genetic architecture of chronic pain in brain and dorsal root ganglia 0.03
1 0.04
Molecular-Based Ecosystem to Improve Personalized Medicine in Chronic Myelomonocytic Leukemia. 0.04
1 0.03
Interaction of genetic and lifestyle risk scores on colorectal cancer risk across five racial and ethnic populations 0.03
2 0.15
Convergent coexpression reveals shared biological mechanisms underlying common and rare variant risk in six neuropsychiatric disorders 0.14
Leveraging transdiagnostic genetic liability to psychiatric disorders to dissect clinical outcomes of anorexia nervosa 0.01
9 0.67
Non-invasive profiling of the tumour microenvironment with spatial ecotypes 0.14
Spatial atlas of diabetic kidney disease reveals a B cell-rich subgroup 0.02
Ancient DNA reveals pervasive directional selection across West Eurasia 0.06
Functional dissection of complex trait variants at single-nucleotide resolution 0.06
Efficient near-telomere-to-telomere assembly of nanopore simplex reads 0.13
Biological insights into schizophrenia from ancestrally diverse populations 0.08
An expanded registry of candidate -regulatory elements 0.10
Mapping the genetic landscape across 14 psychiatric disorders 0.01
Complex genetic variation in nearly complete human genomes 0.07
1 0.18
Reference-free discovery with barcoded single-cell sequencing 0.18
27 9.67
Multi-ancestry transcriptome-wide association studies uncover insights into breast cancer genetics and biology 0.03
A long-read human pangenome initiative for comprehensive interpretation of nuclear-embedded mitochondrial DNA 0.07
Spatially decoding genotype-associated epigenetic landscapes in human lymphoma FFPE tissues via epi-Patho-DBiT 0.78
Leveraging cell-type specificity and similarity improves single-cell eQTL fine-mapping 0.92
CellNiche represents cellular microenvironments in atlas-scale spatial omics data with contrastive learning 0.10
Prediction and functional interpretation of inter-chromosomal genome architecture from DNA sequence with TwinC 0.11
Population differences of chromosome 22q11.2 duplication structure predispose differentially to microdeletion and inversion 0.02
A multi-modal diffusion model with dual-cross-attention for multi-omics data generation and translation 0.20
Simultaneous profiling of native-state proteomes and transcriptomes of neural cell types using proximity labeling 0.39
The global phylogeography of rapidly expanding multidrug resistant Ural lineage 4.2 Mycobacterium tuberculosis 0.55
TONSOKU prevents the formation of large tandem duplications and restrains ATR–WEE1 checkpoint activation 1.00
Genetic modifiers of -ε4-associated cognitive decline 0.01
Metabolic characterization of tumor-immune interactions by multiplexed immunofluorescence reveals spatial mechanisms of immunotherapy response in non-small cell lung carcinoma (NSCLC) 0.44
Community benchmarking and evaluation of human unannotated microprotein detection by mass spectrometry based proteomics 0.09
Central amygdala single-nucleus atlas reveals chromatin and gene transcription dynamics in human alcohol use disorder 0.68
TidyMass2: advancing LC-MS untargeted metabolomics through metabolite origin inference and metabolic feature-based functional module analysis 0.07
Functional implications of polygenic risk for schizophrenia in human neurons 0.08
FastCCC: a permutation-free framework for scalable, robust, and reference-based cell-cell communication analysis in single cell transcriptomics studies 0.67
Targeted sequencing and iterative assembly of near-complete genomes 0.04
Multi-ancestry investigation of the genomics of erectile dysfunction 0.69
ELLA: modeling subcellular spatial variation of gene expression within cells in high-resolution spatial transcriptomics 0.50
UNICORN: Towards universal cellular expression prediction with a multi-task learning framework 1.00
The chronODE framework for modelling multi-omic time series with ordinary differential equations and machine learning 1.00
Machine-learning driven strategies for adapting immunotherapy in metastatic NSCLC 0.03
Cell Marker Accordion: interpretable single-cell and spatial omics annotation in health and disease 0.14
Distribution of copy number alterations and impact of chromosome arm call thresholds for meningioma 0.06
Shared genetic architecture of posttraumatic stress disorder with cardiovascular imaging, risk, and diagnoses 0.03
6 1.39
Interpretable, flexible and spatially aware integration of multiple spatial transcriptomics datasets from diverse sources 1.00
Systematic design of combination therapy by targeting master regulators of coexisting diffuse midline glioma cell states 0.00
Pan-cancer inference and validation of hypermorphic, hypomorphic and neomorphic mutations 0.01
Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction 0.00
Spatially resolved multi-omics of human metabolic dysfunction-associated steatotic liver disease 0.05
A contextual genomic perspective on physical activity and its relationship to health, well being and illness 0.33
4 0.75
SNP calling, haplotype phasing and allele-specific analysis with long RNA-seq reads 0.02
Integration of imaging-based and sequencing-based spatial omics mapping on the same tissue section via DBiTplus 0.68
Pertpy: an end-to-end framework for perturbation analysis 0.05
cellSTAAR: incorporating single-cell-sequencing-based functional data to boost power in rare variant association testing of noncoding regions 0.00
1 0.88
Transcriptomic and phenotypic convergence of neurodevelopmental disorder risk genes in vitro and in vivo 0.88
2 0.39
mFABIO: An integrative multi-tissue TWAS fine-mapping approach to prioritize potentially causal genes and tissues underlying binary traits 0.25
Monkeyflower (Mimulus) uncovers the evolutionary basis of the eukaryote telomere sequence variation 0.14
8 3.57
RETRACTED: PKNOX2 gene is significantly associated with substance dependence in European-origin women 0.75
Quantifying direct genetic signal captured by principal component adjustment 0.25
A high-coverage Neandertal genome from the Altai Mountains reveals population structure among Neandertals 0.15
Identifying genome-by-childhood trauma interactions for depression using a forest-based approach in the UK Biobank and Adolescent Brain Cognitive Development Study 1.00
Bridging unpaired single-cell multimodal data for integrative analyses with SuperMap 0.24
A unified framework for identification of cell-type-specific spatially variable genes in spatial transcriptomic studies 0.13
Machine-learning models based on histological images from healthy donors identify imageQTLs and predict chronological age 1.00
Virulence hierarchies within the Mycobacterium tuberculosis complex 0.06
2 0.79
A marine stem-myriapod from the Silurian Waukesha Lagerstätte, Wisconsin, USA: terrestrial traits pre-date the transition to land 0.25
Microfossil spiral teeth reveal mesopelagic Cyclothone (bristlemouths) fish evolved during the early Palaeogene greenhouse 0.54

Numerical information only (in the tables above) is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International.