Clinical Sciences articles for Netherlands

Time frame: 1 May 2025 - 30 April 2026

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Count: 385

Article ‘Count’ for Clinical Sciences.

Journal Count Share
1 0.05
Evaluation of Malaria Parasite Transmission Competency Using a Nanozyme-Based Immunodiagnostic Targeting Female Gamete Antigen Release 0.05
3 1.88
Additively manufactured shape-morphing implants for the treatment of acetabular defects 0.82
In vitro and in vivo delivery of mRNA to joint cells using polymeric nanoparticles 1.00
Impact of transient versus continuous IL−1β-driven inflammatory 3D models on annulus fibrosus cells 0.07
3 2.72
Leucine supplementation does not attenuate the decline in daily muscle protein synthesis rates or preserve leg muscle mass during leg immobilization in young or older adults: a double-blind randomized trial 0.95
Preoperative plasma short- and branched-chain fatty acids in relation to risk of complications after colorectal cancer surgery: a prospective cohort study 0.77
Vitamin C Status across the Spectrum of Chronic Kidney Disease and Healthy Controls: a Cross-sectional Study 1.00
1 1.00
Rare-variant aggregation highlights disease-linked genes associated with brain volume variation 1.00
2 2.00
Sexual function after the Manchester procedure versus sacrospinous hysteropexy in women treated for uterine prolapse: a planned analysis of a randomized clinical trial 1.00
Differences in pessary support between successful and unsuccessful fit: an analysis in upright position 1.00
3 0.22
Early mechanical reperfusion in high-risk pulmonary embolism supported by V-A ECMO: a multicenter international cohort study 0.02
Telacebec, a Potent Agent in the Fight against Tuberculosis: Findings from a Randomized, Phase 2 Clinical Trial and Beyond 0.14
Physiological Consequences of Breathing Effort According to the Mode of Ventilation During Acute Hypoxemic Respiratory Failure. 0.06
1 0.14
Efficient Compression of Mass Spectrometry Images via Contrastive Learning-Based Encoding 0.14
6 3.00
Intranasal naloxone reversal of opioid-induced respiratory depression in opioid-naïve individuals and self-reported daily opioid users. 0.74
Perspectives of children, parents and health care providers on outcomes following anesthesia for surgery:: An international mixed methods stakeholder engagement study from the Pediatric Perioperative Outcomes Group. 0.09
Individualised Perioperative Blood Pressure and Fluid Therapy in Oesophagectomy a prospective, single-blind randomised controlled trial. 0.07
Heat Loss in Humans Warmed with Various Full-Body Forced-air Heating Systems. 0.20
Fentanyl-induced ventilatory depression: population pharmacokinetic/ pharmacodynamic framework for evaluation of opioid-induced ventilatory depression. 0.95
Recovery of the acute hypoxic ventilatory response after reversal of a minimal neuromuscular block. A randomized, controlled trial in healthy, non-obese volunteers. 0.94
1 0.62
Bio-Propelled Stomatocyte Nanomotors with Glutathione-Responsiveness for Osteoarthritis Treatment 0.62
3 1.13
Proteinuria or Albuminuria as Markers of Kidney and Cardiovascular Disease Risk : An Individual Patient-Level Meta-analysis. 0.11
Long-Term Routine Laboratory Toxicity Monitoring of Immunomodulatory Drugs in Rheumatoid Arthritis : A Retrospective Cohort Study. 1.00
Effects of a Hypotension-Avoidance Versus a Hypertension-Avoidance Strategy on Neurocognitive Outcomes After Noncardiac Surgery. 0.02
2 1.04
Biallelic Variants in the scpiDARS2/i/scp Gene as a Novel Cause of Axonal Charcot–Marie–Tooth Disease 0.04
Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy 1.00
4 1.96
Long-term Follow-up After Hypothermic Oxygenated Machine Perfusion in DCD Liver Transplantation 0.79
Defining Global Benchmarks for Robotic Liver Resections: An International Multicenter Study. 0.01
Perioperative Outcomes in Open Versus Minimally Invasive Gastrectomy For Gastric Cancer: A European Multicenter Study Based on the GASTRODATA Registry. 0.16
Combined Clinical and Histopathological Risk Stratification for Prediction of (severe) Endoscopic Postoperative Recurrence in Patients with Crohn's Disease after Ileocolic Resection: Results from A Prospective Multicenter Cohort Study. 1.00
25 8.78
Topoisomerase 1-DNA complexes are preferentially recognised by a subset of anti-topoisomerase 1 autoantibodies and their corresponding B cell receptors in systemic sclerosis 1.00
Frequency and characteristics of axial involvement in psoriatic arthritis: results from the International Multicentre AXIS Study 0.05
Risk score for early mortality to stratify for intensive SSc therapy in the EUSTAR network: the RESIST score 0.05
Hand-dominant joint involvement pattern associates with favourable, and polyarthritis with unfavourable, treatment response to both csDMARDs and bDMARDs in early rheumatoid arthritis: a combined analysis of NORD-STAR and BeSt trials 0.36
A phase 2, randomised, placebo-controlled study of guselkumab in adults with new-onset or relapsing giant cell arteritis 0.07
The incidence of interstitial lung disease in patients with systemic sclerosis: rate, risk factors and prognostic implications in a EUSTAR cohort analysis (CP 133) 0.09
Untargeted breathomics identifies metabolic signatures of immune activity, intestinal integrity, and fatigue in systemic lupus erythematosus 0.07
Inflammation rather than anticitrullinated protein antibodies is associated with cardiovascular mortality in RA: insights from rheumatoid arthritis and coronary artery disease cohorts 0.42
Development and validation of a model to predict the disease activity score: towards a remote treat-to-target approach for rheumatoid arthritis 1.00
Antimitochondrial antibodies in systemic lupus erythematosus are associated with and predict nephritis, arterial vascular events, and mortality 0.02
Cigarette smoke-primed citrullinated HLA-DR4 T cell reactivity is modulated by γδ-T cells 0.13
A de novo dominant-negative PSMB8 mutation causes severe CANDLE/PRAAS due to arrested proteasome biogenesis 0.10
Final validation of the hierarchical framework for outcomes in axial spondyloarthritis: longitudinal determinants of health-related quality of life 0.46
Development and validation of a Disease Activity index for PSoriatic Arthritis based on 44 joints (DAPSA44) 0.36
Inhibition of structural damage progression with the selective interleukin-23 inhibitor guselkumab in participants with active PsA: results through week 24 of the phase 3b, randomised, double-blind, placebo-controlled APEX study 0.08
Chondrocalcinosis and incident knee osteoarthritis: findings from 2 large prospective cohorts with 20 years of follow-up 0.59
A glossary of signs and symptoms of giant cell arteritis 0.03
Development of bispecific antibodies that drive selective targeted local complement inhibition on rheumatoid arthritis-related antigens 1.00
Highly selective tyrosine kinase 2 inhibition with zasocitinib (TAK-279) improves outcomes in patients with active psoriatic arthritis: a randomised phase 2b study 0.06
Exploring the limit of image resolution for human expert classification of vascular ultrasound images in giant cell arteritis and healthy subjects: the GCA-US-AI project 0.05
Disease-modifying antirheumatic drug–free remission in psoriatic arthritis: is it attainable and sustainable? A large longitudinal study 1.00
Time-independent disease state identification defines distinct trajectories determined by localised vs systemic inflammation in patients with early rheumatoid arthritis 0.52
Epitopes targeted by autoantibodies in presymptomatic individuals predict early rheumatoid arthritis 0.07
Systematic review and independent validation of genetic factors of radiographic outcome in rheumatoid arthritis identifies a genome-wide association with CARD9 0.20
Adalimumab serum concentration to choose a subsequent biological DMARD in patients with rheumatoid arthritis (ADDORA-switch): results of a blinded randomised test-treatment trial 1.00
2 1.25
Effects of Progressive Resistance Training on Cardiovascular Risk Factors in People With Progressive Multiple Sclerosis 1.00
Minimal Important Changes of Common Outcome Measures of Physical Function in Individuals with Knee Osteoarthritis: A Prospective Clinical Study 0.25
6 1.58
18F‐Fluorodeoxyglucose Positron Emission Tomography Imaging Assessment within a Randomized Controlled Trial in Giant Cell Arteritis 0.08
Baseline Interleukin‐10 Levels as a Predictive Biomarker for Achieving Clinical Response With Abatacept in Patients Who Were Disease‐Modifying Antirheumatic Drug Naive and Anti–Citrullinated Protein Antibody Positive With Early Rheumatoid Arthritis 0.07
Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand? 0.14
Effect of time to start of biologic therapy on treatment response in childhood arthritis: Results from the UCAN CAN‐DU study 0.67
Clinical Impact of Multiparametric Contrast‐Enhanced Dual‐Energy Computed Tomography in Arthritis Imaging: A Prospective Single‐Center Study 0.10
Differences in Dynamics of Specific Antinuclear Antibodies and Their Susceptibility to B Cell–Targeting Treatment in Patients With Systemic Lupus Erythematosus 0.53
3 0.39
Biological classification of memory clinic patients 0.17
Connectivity as a universal predictor of tau progression in atypical Alzheimer’s disease 0.10
Modelling fragile X-associated neuropsychiatric disorders in young inducible 90CGG premutation mice 0.13
8 4.64
Performance indicators for organ donation and transplantation programmes in Europe: modified Delphi consensus study 0.06
Parallel Endografting And Chimney Endovascular (PEACE) registry outcomes in emergency repair of complex abdominal aortic aneurysms 0.07
Treatment strategies for Boerhaave syndrome: multinational retrospective cohort study 0.24
Variation in outcomes after metabolic bariatric surgery: multilevel analysis to assess the contribution of patient, surgeon, and hospital factors 1.00
Quilt technique after mastectomy: stepped-wedge randomized cluster trial showing superior textbook outcome and reduced healthcare utilization 1.00
Prevalence and severity of pain, anxiety, stress, and sleep disturbances among surgical patients: a nationwide single-day multicentre flash mob study 1.00
Validation of the Swiss-Finnish Bariatric Metabolic Outcome Score within a large prospective registry cohort 0.27
Comparison of revision surgery after implant-based breast reconstruction between smooth, textured, and polyurethane-covered implants: results from the Dutch Breast Implant Registry 1.00
1 0.10
Genetic modifiers and ascertainment drive variable expressivity of complex disorders 0.10
3 1.65
Molecular basis of 60 years of antigenic evolution of human influenza A(H3N2) virus neuraminidase 0.63
Bacteriophage genomes encode both broad and specific counter-defense repertoires to overcome bacterial defense systems 0.95
Phage arabinosyl-hydroxy-cytosine DNA modifications result in distinct evasion and sensitivity responses to phage defense systems 0.07
4 0.38
Plasma proteomic signature of frailty in 50,506 adults 0.06
Blood-flow restriction resistance training improves skeletal muscle mitochondrial capacity and cardiovascular risk factors in type 2 diabetes 0.08
HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes 0.14
Sphingomyelins in mosquito saliva reconfigure skin lipidome to promote viral protein levels and enhance transmission of flaviviruses 0.11
13 5.48
Virological Failure on Long-Acting Injectable Cabotegravir and Rilpivirine: An Analysis of Subtypes, Drug Levels, Resistance, and Therapeutic Implications 0.38
“Bone biopsy not superior to ulcer bed biopsy guided antibacterial therapy on remission of diabetic foot osteomyelitis: A randomized controlled trial” 0.92
Reproducible Identification of Staphylococcus aureus Bacteremia Clinical Subphenotypes 0.38
Estimating the Accuracy and Additionality of TB-LAM to Diagnose TB in Children Without HIV (AccuLAM) 0.07
Continuation Versus Temporary Interruption of Immunomodulatory Agents During Infections in Patients With Inflammatory Rheumatic Diseases: A Randomized Controlled Trial 1.00
Long-term Immunogenicity and Boostability of the 13-valent Pneumococcal Conjugate Vaccine Followed by the 23-valent Pneumococcal Polysaccharide Vaccine in Adults Receiving Immunosuppressive Therapy and Adults Living With HIV—3-year Follow-up of a Prospective Cohort Study 1.00
Sputum and tongue swab molecular testing for the in-home diagnosis of tuberculosis in unselected household contacts: a cost and cost-effectiveness analysis 0.03
Impact of Sonication Fluid Cultures on Prosthetic Joint Infection Diagnosis and Management: A Microbiology-Driven Evaluation Using IDSA and EBJIS Criteria 0.89
Projecting the Impact and Costs of Near Point-of-Care Tuberculosis Screening Assays in Community-based Active Case Finding 0.25
Stool processing methods for Xpert Ultra testing in childhood tuberculosis: A prospective, multi-country accuracy study 0.09
Effectiveness of a Home-based Approach to Child Contact Investigation and TPT Management by Community Health Workers in Ethiopia: A Pragmatic Cluster-randomized Trial 0.11
Risk of Cancer in People With Human Immunodeficiency Virus Experiencing Varying Degrees of Immune Recovery With Sustained Virological Suppression on Antiretroviral Treatment for More Than 2 Years: An International, Multicenter, Observational Cohort 0.07
Modeling the Impact and Cost of a Culture-Dependent Molecular Test for Antimicrobial Resistance in Resource-Limited Settings 0.31
12 6.11
The Influence of Older Age on RBC Transfusion Decisions in ICU Patients. 0.24
Power, Duration, and Compliance: Reframing Risk of Ventilatory-Induced Lung Injury With the Risk-Adjusted Mechanical-Power Score. 0.50
Effect of a Lower Vs. Higher Positive End-Expiratory Pressure Strategy on Clinically Relevant Outcomes in ICU Patients Without Acute Respiratory Distress Syndrome: Bayesian Re-analysis of the REstricted Vs. Liberal Positive End-Expiratory Pressure in Patients Without Acute Respiratory Distress Syndrome (RELAx) Randomized Clinical Trial. 0.67
Sex-Specific Differences in Tidal Volumes and Mortality of Mechanically Ventilated Patients. 0.05
Conversion From Venovenous to Venoarterial or Hybrid Extracorporeal Membrane Oxygenation: Analysis From the Extracorporeal Life Support Organization Registry. 0.24
Minimal Gain in Prognostic Certainty for Patients With Hematologic Malignancies Over 2 Weeks of Intensive Care: An Analysis to Inform Time-Limited Trials. 1.00
Five Years After Extracorporeal Membrane Oxygenation: A Prospective Cohort Study of Health-Related Quality of Life and Patient Outcomes. 0.94
Platelet Transfusion Practices in the ICU: A Prospective Multicenter Cohort Study. 0.25
Differentiating Lung From Chest Wall Mechanics Is Difficult Without Esophageal Manometry in Children With Acute Respiratory Distress Syndrome. 0.10
Enhancing Quality of Care Assessments: Managing Atypical Patients in ICU Benchmarking in The Netherlands. 1.00
P0.1 is an Unreliable Measure of Effort in Support Mechanical Ventilation in Comparison With Esophageal-Derived Measures of Effort: A Comparison Study. 1.00
Persistent Critical Illness Among Intensive Care Patients in India: A Registry-Embedded Cohort Study. 0.13
1 0.67
Longitudinal assessment of total daily energy expenditure in professional cyclists supports a maximal sustainable metabolic ceiling 0.67
4 0.96
Impact of Metabolic Bariatric Surgery on Weight Loss and Glycemic Control in Adults With Type 1 Diabetes: A Multicenter Retrospective Cohort Study. 0.34
Impact of Baseline GLP-1 Receptor Agonist Use on Albuminuria Reduction and Safety With Simultaneous Initiation of Finerenone and Empagliflozin in Type 2 Diabetes and Chronic Kidney Disease (CONFIDENCE Trial). 0.07
Dementia Risk in People With Type 1 Diabetes and Associated Risk Factors: A Nationwide, Register-Based Cohort Study. 0.50
Risk of Phimosis Associated With SGLT2i Versus GLP-1RA: A Danish Cohort Study. 0.06
3 2.06
Associations of residential environmental factors with kidney function in older adults in the Netherlands: A cross-sectional and longitudinal study 1.00
Environmental exposure to endocrine disruptors induces insulin resistance and hepatic inflammation in adult male rats, with partial transmission across subsequent generations 0.06
Transfer of antibiotic residues from digestate-amended soil to edible crops in a circular food production system 1.00
3 1.67
Fetal exposure to bisphenols and phthalates and risk of respiratory conditions in infancy. The Generation R Next Study 0.50
Occupational and environmental livestock exposures are associated with alterations in the upper respiratory tract microbiome 1.00
Impact of summer heat on male children's physiological responses during football training 0.17
4 1.10
Silent plaque ruptures in non-obstructive lesions of non–infarct-related arteries: a multimodality, serial intracoronary imaging study 0.13
Urinary tract infection and continuation of sodium-glucose cotransporter-2 inhibitors in diabetic patients 0.02
Artificial intelligence-based identification of thin-cap fibroatheromas and clinical outcomes: the PECTUS-AI study 0.93
Accelerated vascular ageing after COVID-19 infection: the CARTESIAN study 0.02
3 1.15
The Gut Microbiome at the Onset of Inflammatory Bowel Disease: A Systematic Review and Unified Bioinformatic Synthesis 0.09
Intestinal LKB1 Loss Drives a Premalignant Program Along the Serrated Cancer Pathway 1.00
Early infliximab levels and clearance predict outcomes after infliximab rescue in acute severe ulcerative colitis: Results from PREDICT-UC 0.06
9 2.02
Commonly prescribed drugs as risk factors for Clostridioides difficile infections: a Swedish population-based case–control study 0.14
Associations between demographic, clinical and dietary factors and flares in inflammatory bowel disease: the PRognostic effect of Environmental factors in Crohn’s and Colitis (PREdiCCt) prospective cohort study 0.03
<atl>Novel imyo/i -inositol to butyrate fermentation pathway in the prevalent human gut species iDysosmobacter welbionis,/i a bacterium associated with improved metabolic and liver health</atl> 0.10
Genetic dissection of stool frequency implicates vitamin B1 metabolism and other actionable pathways in the modulation of gut motility 0.24
Intestinal blood vessel-associated macrophages and gut-vascular barrier dysfunction in cirrhosis 0.02
First genome-wide association study reveals immune-mediated aetiopathology in idiopathic achalasia 0.01
Crohn’s disease and ulcerative colitis exhibit prediagnostic antibody signatures with shared and divergent changes towards disease onset 0.42
Results of endoscopic intermuscular dissection for deep submucosal invasive rectal cancer: a three-year follow-up study 1.00
CagA-dependent Hobit+ gastric tissue-resident memory T cells confer full protection from Helicobacter pylori reinfection 0.07
6 1.06
Toxic lipid-induced epigenetic activation of ICAM1 in liver sinusoidal endothelium regulates myeloid-driven fibro-inflammatory response in MASH. 0.16
Original research: Amplification of genetic and metabolic factors in alpha-1 antitrypsin deficiency. 0.09
Understanding hepatopancreatobiliary cancer risks in a population-based primary sclerosing cholangitis-inflammatory bowel disease cohort. 0.04
Predictors of fibrosis, clinical events and mortality in MASLD: Data from the Global-MASLD study. 0.01
Global performance of non-invasive tests in MASLD: Insights from the G-MASLD study. 0.01
Comparison of diagnostic accuracy and utility of non-invasive tests for clinically significant liver disease in a general population with metabolic dysfunction. 0.77
3 2.55
A clinical protocol for the detection of comorbidities associated with monogenic causes of male infertility 0.93
Studies of post-partum placentas provide insights into the origin of structural chromosomal aberrations 0.89
Preimplantation genetic testing for neurofibromatosis type 1: molecular genetic aspects and impact on reproductive counseling 0.73
2 0.61
Genetically diverse influenza antibodies highlight the role of IG germline gene variation and inform population-comprehensive vaccine strategies 0.06
Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity 0.55
2 0.13
Malaria amidst the COVID-19 pandemic in Gabon: an application of autoregressive integrated moving average (ARIMA) models within an interrupted time series (ITS) framework to hospital-based data 0.04
Post-acute non-specific symptoms following COVID-19 vaccination: a Danish population-based study 0.08
3 1.91
Association of body mass index, waist circumference, (abdominal) overweight and obesity with sex- and age-specific cognitive function over time—the Doetinchem Cohort Study 1.00
Real world efficacy of naltrexone/bupropion for weight management in obesity and after bariatric surgery 0.05
The long-term effect of metabolic bariatric surgery on innate immune cell phenotype and function 0.87
1 0.17
Effectiveness and Cost-Effectiveness of Automated External Defibrillators in Private Homes 0.17
3 1.29
Dialectical Behavior Therapy vs Schema Therapy for Patients With Borderline Personality Disorder 0.93
The Role of Energy Homeostasis in Depression Pathophysiology and Its Heterogeneity 0.33
Framework for Brain-Derived Dimensions of Psychopathology 0.03
4 3.05
Small Bites vs Large Bites for Closure of Abdominal Midline Incisions 1.00
Postoperative Pulmonary Complications in Conventional Laparoscopic vs Robot-Assisted Abdominal Surgery 0.17
Prevention of Incisional Hernias With Prophylactic Synthetic Mesh Placement During Stoma Reversal 1.00
Intercostal or Paravertebral Block vs Thoracic Epidural in Lung Surgery 0.88
7 2.61
Discontinuation of Levothyroxine in Adults Aged 60 Years or Older 1.00
Effect of Automated Closed-Loop Ventilation vs Protocolized Conventional Ventilation on Ventilator-Free Days in Critically Ill Adults 0.71
Intraoperative Driving Pressure–Guided High PEEP vs Standard Low PEEP for Postoperative Pulmonary Complications 0.73
Discordance in Creatinine- and Cystatin C–Based eGFR and Clinical Outcomes 0.07
Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score 0.03
Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock 0.00
Lorundrostat in Participants With Uncontrolled Hypertension and Treatment-Resistant Hypertension 0.08
1 0.22
Dominant-negative NARS1 R534∗ mutation causes wild-type subunit poisoning and heterodimer predominance in cells 0.22
3 1.35
Minimal Movement Restrictions Do Not Increase Hip Dislocations Following Total Hip Arthroplasty 1.00
Risk Factors for Nonunion Following Lateral Locked Plating of Distal Femoral Fractures 0.25
Outcomes Associated with Choice of Prophylactic Antibiotics in Open Fractures 0.10
13 10.34
Health-related quality of life in children with multiple endocrine neoplasia (MEN) and their siblings 1.00
Pregnancy-specific Reference Intervals for TSH and FT4: Novel Insights From Preconception-gestation Longitudinal Data 1.00
Fasting vs Nonfasting, Dose-adjusted Levothyroxine Ingestion in Hypothyroidism: A Randomized Clinical Trial 1.00
Muscle and liver insulin resistance are associated with distinct plasma protein profiles; data from the DiOGenes trial 1.00
Thyroid function and all-cause mortality in the context of multimorbidity: results from two population-based studies 1.00
Myofibrillar Protein Synthesis Rates Do not Differ With Low and High Estradiol Concentrations Across the Menstrual Cycle 0.05
Near-Adult Height Outcomes in Patients Treated With rhIGF-1 for Severe Growth Failure: Real-World IGFD Registry Data 0.10
Circulating Gene Expression Assay as a Diagnostic and Prognostic Biomarker for Pancreatic Neuroendocrine Tumors in MEN1 1.00
Maternal Thyroid Function During Pregnancy and Early Adolescent Regional Differences in Cerebral Gray Matter Morphology 0.90
Hair Cortisone Levels and the Metabolic Syndrome: Stronger Links in Younger Compared to Older Adults 1.00
MCT8 Deficiency in Females 0.36
Clinical Characteristics and Response to Growth Hormone Treatment in 27 Children With Heterozygous NPR2 Variants: Real-World Data 1.00
Serum 5-Hydroxyindoleacetic Acid Measurements for the Diagnosis and Follow-up of Carcinoid Syndrome 0.93
2 0.07
Rapid and profound decay of inducible and intact HIV genomes in early treated Thai children 0.04
Metabolic surgery mitigates early kidney injury in obese youth with diabetes by suppressing mTORC1/JAK–STAT signaling 0.02
1 0.10
New Validated Staging System for Light Chain (AL) Amyloidosis With Stage IIIC Defining Ultra-Poor Risk: AL International Staging System. 0.10
3 0.11
Consensus position statements for the standardized application of histological grading and staging systems in MASH clinical trials 0.04
Prognostic value of liver stiffness measurement vs. biochemical response in primary biliary cholangitis 0.04
Rivaroxaban to prevent complications of portal hypertension in cirrhosis: The CIRROXABAN study 0.03
9 4.14
Treatment Monitoring and Outcome Prediction in Invasive Aspergillosis Using Immunologic Markers 0.11
Efficient sensing of a four-segmented Rift Valley fever virus vaccine candidate by human monocytes 0.17
High Prevalence and Genotypic Diversity of Persistent Chlamydia Trachomatis Infections Among South African Adolescent Girls and Young Women: A Tale of Two Cities 0.12
Functional and transcriptional senescence profiles of CD8+ T cells associate with the presence of carotid plaques in people living with HIV 0.87
Manufacture of Clostridioides difficile Spores for Experimental Infection of Human Volunteers 1.00
Gut microbiota predicts the risk of future COVID-19 hospitalization and mortality: insights from the population-based HELIUS Study 1.00
Genome-Scale Meta-analysis of Host Responses to iStaphylococcus aureus/i Identifies Pathways for Host-Directed Therapeutic Targeting 0.05
Estimating Zika Virus Seroprevalence in a Dengue Virus–Endemic Population: The Use of Blood Donors and Multiplex Serology to Monitor Arbovirus Outbreaks in the Dutch Caribbean 0.71
Mind the Clinic-Community Gap: Re-evaluation of Test Performance and False Positive Results in Community-Wide Tuberculosis Screening 0.12
7 4.85
Activation by alcohol of prefrontal layer 5 pyramidal neurons depends on ascending dopaminergic input 0.13
Improving emotion control in social anxiety by targeting rhythmic brain circuits 1.00
Neural Tuning for Ordinal Processing: Convergent Patterns in Human Brains and Artificial Networks 1.00
Anterior insula activity during alcohol and social reward self-administration and choice in male and female rats. 1.00
DMT-induced shifts in criticality correlate with self-dissolution 0.50
Dual Role of LH-GABA Neurons in Encoding Alcohol Reward and Aversive Memories 1.00
Neural and Behavioral Markers of Negative Symptoms and Cognitive Impairment in Patients with Psychosis 0.22
3 1.15
Examining Features of Atypical Depression in Youth From the Texas Youth Depression and Suicide Research Network Research Registry 0.08
Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-Analysis 0.17
Enduring Mental Health in Childhood and Adolescence: Prevalence, Prediction, and Genetic Architecture 0.90
5 2.09
Surgical excision versus topical 5% 5-fluorouracil and photodynamic therapy in the treatment of Bowen's disease: long-term results of a multicenter randomized controlled trial 1.00
Joint Position Statement from the National Psoriasis Foundation Medical Board and the International Psoriasis Council on Routine Testing for Latent Tuberculosis Infection Prior To and During Treatment of Psoriasis Patients with IL-17 or IL-23 Inhibitors 0.03
Clinical Practice Guidelines for the Management of Basal Cell Carcinoma in Gorlin Syndrome 0.02
Establishment of standardized definitions and a core set of outcome characteristics following hidradenitis suppurativa surgery developed by an expert Delphi consensus 0.13
Enhanced metastatic risk stratification for Cutaneous Squamous Cell Carcinoma by combining clinical guidelines with the Erasmus MC model: Results from Two Nationwide Nested Case-Control Studies 0.91
1 0.12
Chemical Synthesis of Oligosaccharides Derived from Streptococcus Pneumoniae Serotype 35B and D Provides Molecular Insight in l-Ficolin Binding 0.12
4 0.78
Myocardial Amyloid Burden in Transthyretin Amyloidosis 0.04
Risk of Hyperkalemia With Empagliflozin, Finerenone, or Both: Secondary Analysis of CONFIDENCE Randomized Trial 0.07
PCI of Native Coronary Artery vs Saphenous Vein Graft After Prior Bypass Surgery A Multicenter, Randomized Trial 0.63
Effect of Acoramidis on Recurrent and Cumulative Cardiovascular Outcomes in ATTR-CM: Exploratory Analysis from ATTRibute-CM 0.05
1 0.75
Impact of the 2015 Dutch Long‐Term Care Reform on Nursing Home Use and Access for People With Dementia 0.75
9 2.08
Efficacy and Safety of Atrasentan in Patients with IgA Nephropathy Receiving Sodium-Glucose Cotransporter 2 Inhibitors: Placebo-Controlled, Crossover Trial. 0.02
Inhibition of Interleukin-33 in Diabetic Kidney Disease 0.04
Integrin Alpha1 Beta1 Promotes Interstitial Fibrosis and Cyst Growth in a Mouse Model of Polycystic Kidney Disease​ 0.17
Spatial Transcriptomics Reveals Injured Cells, Signature Genes, and Communication Patterns in the Cyst Microenvironment of Polycystic Kidney Disease. 1.00
Effect of Finerenone on Morbidity and Mortality in CKD. 0.04
Effects of Dapagliflozin on Health-Related Quality of Life in Patients with CKD. 0.38
Use of eGFR Slope Thresholds as End Point Components in a Kidney Disease Progression Hierarchical Composite End Point. 0.21
Kidney Parameters with Tirzepatide in Obesity with or without Type 2 Diabetes. 0.15
Obesity, Underweight, and Accuracy of eGFR Using Cystatin C and Creatinine in a Northern European Population. 0.06
4 2.06
FaceAge as a biomarker for prognosis and treatment stratification in large-scale oncology cohort 0.22
Liver fat and clinical outcomes in individuals with stage I-iii Colon or rectal cancer 0.75
Basal cell carcinoma risk prediction in survivors of childhood cancer 0.09
Breast implant illness after reconstruction with silicone breast implants 1.00
2 0.36
Population-based estimated Glomerular Filtration Rate distributions and associated health outcomes provide opportunities for early identification of and primary prevention of chronic kidney disease 0.05
Causal assessment of CKD-MBD biomarker alterations on CKD progression through a g-formula analysis in the EQUAL Study 0.31
1 0.82
Molecular basis for anti-jumbo phage immunity by AVAST type 5 0.82
12 1.34
Multiscale characterization of cortical signatures in positive and negative schizotypy: a worldwide ENIGMA study 0.08
Local chemoarchitecture explains widespread lower cortical thickness associated with clinical high risk for psychosis 0.06
Cortical morphometry might predict currently prescribed vs. discontinued medications in bipolar disorder, even after controlling for the cumulative dose effects: An ENIGMA mega-analysis 0.01
Spatiotemporal mapping of brain organisation following the administration of 2C-B and psilocybin 0.60
Psychotropic medications and their interactions with subcortical brain volume in bipolar disorder: An ENIGMA mega-analysis 0.01
Structural brain differences associated with panic disorder: an ENIGMA-Anxiety Working Group mega-analysis of 4924 individuals worldwide 0.11
Structural brain abnormalities and aggression in schizophrenia: mega-analysis of data from 2095 patients and 2861 healthy controls via the ENIGMA consortium 0.08
Regional brain morphology and current antidepressant use: findings from 32 international cohorts from the ENIGMA major depressive disorder working group 0.09
GRIN2A null variants confer a high risk for early-onset schizophrenia and other mental disorders and potentially enable precision therapy 0.06
A low frequency damaging SORCS2 variant identified in a family with ADHD compromises receptor stability and quenches activity 0.04
Hippocampal Cofilin and CFL1 gene variants are linked to Alcohol Use Disorder phenotypes 0.05
Long term safety of ADHD medication in patients with schizophrenia spectrum disorders 0.14
3 0.22
Rare genetic variants confer a high risk of ADHD and implicate neuronal biology 0.13
mAChR4 suppresses liver disease via GAP-induced antimicrobial immunity 0.02
Nutrients activate distinct patterns of small-intestinal enteric neurons 0.08
56 18.31
Face aging rate quantifies change in biological age to predict cancer outcomes 0.10
Prolonged β2-agonist treatment enhances muscle-specific glucose uptake in individuals with overweight and obesity: a randomized placebo-controlled trial 0.85
Multiomics characterization of acute child illness and mortality in Africa and South Asia 0.01
A group 1 hemagglutinin stem vaccine elicits broad humoral responses against influenza in phase 1/2a study 0.95
Real-world evidence for comparative safety of second-line antihyperglycemic agents in older adults with type 2 diabetes 0.01
Pathogenic variants in the cohesin loader subunit MAU2 underlie a distinct Cornelia de Lange Syndrome subtype 0.02
Noradrenaline causes a spread of association in the hippocampal cognitive map 0.06
Segmented filamentous bacteria are worldwide human gut commensals 0.02
Disrupted temperature-sleep coupling mechanism in a Dravet syndrome mouse model 0.18
Photochemical nanomotors reverse anxiety- and depressive-related behaviors in rodents via spatiotemporal polarity dynamics tuning 0.09
Using electronic health records to assess the relationship between colonization pressure and nosocomial pathogen acquisition 0.04
The genetic landscape of human functional brain connectivity 1.00
The effects of a second pregnancy on women’s brain structure and function 1.00
Loss-of-function variants in the CAPN1 activator cause X-linked spastic ataxia 0.03
The interplay of sleep characteristics with health factors and gut microbiome 0.96
Opposite effects of chronic HIV infection and antiretroviral medication on organismal and organ-specific biological aging 0.74
Latent transition analysis for longitudinal studies of post-acute infection syndromes 0.10
Urinary clusterin as a biomarker of human kidney disease progression and response to the endothelin receptor antagonist atrasentan: An exploratory analysis from the SONAR trial 0.16
A stabilized tandem antigen chimera that elicits potent malaria transmission-reducing activity 0.20
Using the linear references from the pangenome to discover missing autism variants 0.00
Longitudinal plasma proteomic signatures of elite and viremic spontaneous HIV controllers 0.68
Circadian rhythm profiles derived from accelerometer measures of the sleep-wake cycle in two cohort studies 0.11
Immunological and transcriptomic profile of chimeric live-attenuated Zika vaccine linked to protection in non-human primates 0.25
Impact and cost-effectiveness of the community-led AMETHIST intervention among female sex workers in Zimbabwe 0.07
Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift 0.32
Prolonged disease remission of the chronic immunological skin disorder hidradenitis suppurativa with adjunctive bacteriophage therapy 0.02
Nucleoplasmic Lamin A/C controls replication fork restart upon stress by modulating local H3K9me3 and ADP-ribosylation levels 0.25
Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma 0.05
Harnessing registry data to identify socio-demographic and socio-economic gaps in HIV care in the Netherlands 0.94
Estimation of the epidemiological characteristics of scabies 0.83
A de novo missense variant in MIDEAS results in increased deacetylase activity of the MiDAC HDAC complex causing a neurodevelopmental syndrome 0.44
HIV-1 envelope trimer vaccine induces sex-associated differences in antibody responses: a phase 1 clinical trial 0.47
Psilocybin alters visual contextual computations 0.80
Single versus combination treatment in tinnitus: an international, multicentre, parallel-arm, superiority, randomised controlled trial 0.02
Gli1-expressing stromal cells are highly reparative precursors of long-lived chondroprogenitors in the fetal murine limb 0.03
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database 0.01
Microbial binding module employs sophisticated clustered saccharide patches to selectively adhere to mucins 0.02
Experimental glycopeptide antibiotic EVG7 prevents recurrent Clostridioides difficile infection by sparing members of the Lachnospiraceae family 0.80
Neural correlates of human fear conditioning and sources of variability in 2199 individuals 0.07
One Health approach uncovers emergence and dynamics of Usutu and West Nile viruses in the Netherlands 1.00
DeepISLES: a clinically validated ischemic stroke segmentation model from the ISLES'22 challenge 0.03
Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations 0.00
Exome analysis links kidney malformations to developmental disorders and reveals causal genes 0.03
Combining mucosal microbiome and host multi-omics data shows prognostic potential in paediatric ulcerative colitis 0.05
Long-term effect of temporary ART initiated during primary HIV-1 infection on viral persistence 0.92
An all-in-one pipeline for the in vitro discovery and in vivo testing of Plasmodium falciparum malaria transmission blocking drugs 0.16
Transcriptomic decoding of surface-based imaging phenotypes and its application to pharmacotranscriptomics 0.08
Striatal dopamine can enhance both fast working memory, and slow reinforcement learning, while reducing implicit effort cost sensitivity 0.50
Negativeome characterization and decontamination in early-life virome studies 1.00
Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis 0.03
Ethnic disparities in COVID-19 mortality and cardiovascular disease in England and Wales between 2020-2022 0.03
Assembly and the gating mechanism of the Pel exopolysaccharide export complex PelBC of Pseudomonas aeruginosa 0.25
Antigen persistence and TLR stimulation contribute to induction of a durable HIV-1-specific neutralizing antibody response 0.07
Efficient mRNA delivery to resting T cells to reverse HIV latency 0.04
A comparison of intramuscular (Zimhi) and intranasal naloxone (Narcan) in reversal of fentanyl-induced apnea: a randomized, crossover, open-label trial 0.96
Molecular mechanism of thyroxine transport by monocarboxylate transporters 0.45
3 0.07
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling 0.05
Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression 0.02
Genome-wide association study of long COVID 0.01
1 0.04
Quantifying the impact of hair and skin characteristics on fNIRS signal quality for enhanced inclusivity 0.04
2 0.13
TGF-β mediates epigenetic control of innate antiviral responses and SIV reservoir size 0.08
Identification of a potent V3 glycan site broadly neutralizing antibody targeting an N332 glycan-independent epitope 0.05
9 1.65
An international mega-analysis of psychedelic drug effects on brain circuit function 0.15
Blood phosphorylated tau elevation as a biomarker in immunoglobulin light chain and transthyretin amyloidosis 0.13
Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study 0.00
Estimating the number of incorrect tuberculosis diagnoses in low- and middle-income countries 0.13
A meta-analysis of albuminuria as a surrogate endpoint for kidney failure 0.01
Neoadjuvant ipilimumab and nivolumab in resectable cutaneous squamous cell carcinoma: a randomized phase 2 trial 0.97
A consensus blood transcriptomic framework for sepsis 0.19
Adjunct-to-insulin therapy using SGLT2 inhibitors in youth with type 1 diabetes: a randomized controlled trial 0.05
An international Delphi consensus for reporting of setting in psychedelic clinical trials 0.03
2 0.69
Noradrenergic activation of the basolateral amygdala facilitates memory specificity for similar events experienced close in time 0.67
A common computational and neural anomaly across mouse models of autism 0.02
1 0.38
Structural elucidation of full-length Pfs48/45 in complex with potent monoclonal antibodies isolated from a naturally exposed individual 0.38
1 0.17
Adaptive reinforcement learning is causally supported by anterior cingulate cortex and striatum 0.17
1 0.17
Catecholamines reduce choice history biases in perceptual decision making. 0.17
4 1.52
Evaluation of economic strengthening in South Africa and its impact on HIV, sexually transmitted infections, and teenage births: A modelling study 0.08
Clinical and economic impact of genome-wide non-invasive prenatal testing (NIPT) as a first-tier screening method compared to targeted NIPT and first-trimester combined testing: A modeling study 1.00
Effect of pre-exposure prophylaxis on risky sexual behaviour of female sex workers in Dakar, Senegal: A randomised controlled trial 0.25
The transmission blocking activity of artemisinin-combination, non-artemisinin, and 8-aminoquinoline antimalarial therapies: A pooled analysis of individual participant data 0.18
9 5.07
Paramyxovirus infection driven by heteromultivalent sialoglycotope binding 0.87
An accurate cellular assay to determine pathogenicity of coding and noncoding variants in Lynch syndrome genes 1.00
Mesoscale imaging of the human cerebellum reveals converging regional specialization of its morphology, vasculature, and cytoarchitecture 0.97
NPC1 trafficking via VPS41-dependent LAMP carriers regulates endosomal cholesterol homeostasis 0.86
Testing paradox may explain increased observed prevalence of bacterial STIs among MSM on HIV PrEP: A modeling study 0.07
Structural and functional analysis of the Mycobacterium tuberculosis MmpS5L5 efflux pump presages increased bedaquiline resistance 0.10
Joint models reveal human subcortical underpinnings of choice and learning behavior 0.89
The great phage escape: Activating and escaping lactococcal antiphage systems 0.27
Protein kinase A signaling regulates immune evasion by shaving and concealing fungal β-1,3-glucan 0.04
6 2.01
Midbrain Energy Homeostasis Biomarker for Differential Diagnosis of Early-Stage Parkinson Disease: A 1H and 31P MRI Study. 0.17
T1/T2-weighted Ratio to Improve MRI-guided Focused Ultrasound-induced Chronic Lesion Contrast in Patients with Tremor Syndrome. 0.08
Prevalence and Incidence of Paramagnetic Rim Lesions in Multiple Sclerosis: A Systematic Review and Meta-Analysis. 0.06
Comparison of a Specialized Large Language Model with GPT-4o for CT and MRI Radiology Report Summarization. 0.15
A Data-Centric Approach to Deep Learning for Brain Metastasis Analysis at MRI. 0.55
Four-Dimensional Similarity Filter for Cerebral CT Perfusion Maps in Acute Stroke. 1.00
3 0.33
HNF1B integrates signals in a feed-forward loop driving kidney disease progression 0.06
A metabolite-based resistance mechanism against malaria 0.03
Precise targeting of HIV broadly neutralizing antibody precursors in humans 0.24
7 4.89
The human amygdala in threat learning and extinction 0.89
Whole-brain meso-vein imaging in living humans using fast 7-T MRI 0.41
Pfs230 domain 12 is a potent malaria transmission–blocking vaccine candidate 0.67
The designer cytokine IC7Fc attenuates atherosclerosis development by targeting hyperlipidemia in mice 0.72
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail 0.20
Neuropeptide Y neurons surrounding the locus coeruleus inhibit noradrenergic system activity to reduce anxiety 1.00
Mobile human brain imaging using functional ultrasound 1.00
3 0.16
NKX6.1 mRNA copy number is an actionable biomarker associated with islet function and clinical outcomes after islet transplantation 0.10
Anakinra restores immunological misfiring that drives influenza-associated pulmonary aspergillosis 0.05
Synchronized dynamics of dengue across the Americas 0.02
2 0.08
Benefits and harms of ADHD interventions: umbrella review and platform for shared decision making 0.06
Medications for adults with type 2 diabetes: a living systematic review and network meta-analysis 0.03
2 1.01
Notch signaling is a driver of glandular stem cell activity and regenerative migration after damage 0.87
Phosphoribosyl ubiquitination of SNARE proteins regulates autophagy during Legionella infection. 0.13
2 1.13
Rapid resistance evolution against phage cocktails 1.00
Vitamin auxotrophies shape microbial community assembly on model marine particles 0.13
1 0.73
Dissecting key contributions of Th2 and Th17 cytokines to atopic dermatitis pathophysiology 0.73
3 0.16
Balcinrenone in combination with dapagliflozin compared with dapagliflozin alone in patients with chronic kidney disease and albuminuria: a randomised, active-controlled double-blind, phase 2b clinical trial 0.08
Once-daily oral icotrokinra versus placebo and once-daily oral deucravacitinib in participants with moderate-to-severe plaque psoriasis (ICONIC-ADVANCE 1 & 2): two phase 3, randomised, placebo-controlled and active-comparator-controlled trials 0.03
Efficacy and safety of intravenous induction and subcutaneous maintenance therapy with guselkumab for patients with Crohn's disease (GALAXI-2 and GALAXI-3): 48-week results from two phase 3, randomised, placebo and active comparator-controlled, double-blind, triple-dummy trials 0.05
4 0.38
Effect of surgical versus conservative management on cardiovascular outcomes in patients with bilateral adrenal tumours and cortisol excess: an international, retrospective cohort study 0.04
Cycle characterisation and clinical complications in patients with cyclic Cushing's syndrome: insights from an international retrospective cohort study 0.01
Association of gestational thyroid function and thyroid autoimmunity with gestational diabetes: a systematic review and individual participant meta-analysis 0.18
Treatments for MEN1-associated endocrine tumours: three systematic reviews and a meta-analysis 0.14
1 0.26
Guiding the development of the tuberculosis screening target product profile using single-screen and multi-screen approaches: a modelling study 0.26
2 0.36
Transdiagnostic effectiveness and safety of clozapine in individuals with psychotic, affective, and personality disorders: nationwide and meta-analytic comparisons with other antipsychotics 0.25
The global epidemiology of personality disorder: a systematic review and meta-regression 0.11
8 0.77
Pulmonary Tuberculosis Detection with MiniDock MTB Using Swab Samples 0.04
IVUS-Guided versus Angiography-Guided PCI in Unprotected Left Main Coronary Disease 0.13
Intravascular Ultrasound–Guided or Angiography-Guided Complex High-Risk PCI 0.30
Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism 0.07
Finerenone in Type 1 Diabetes and Chronic Kidney Disease 0.07
A Phase 3 Trial of Telitacicept for Systemic Lupus Erythematosus 0.05
Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes 0.05
Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes 0.07
3 1.24
Tracking norovirus diversity at a global scale through wastewater metagenomics 0.89
Estimating the consumption of prescription opioids through wastewater analysis: The patterns of use in Italy 0.17
Contrast-Enhanced Micro-Computed Tomography for 3D Imaging of Biofilms in Opaque Materials: Insights from Water Treatment Plant Sand Filters 0.19

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