Clinical Sciences articles for Harvard University, United States of America (USA)

Time frame: 1 June 2025 - 30 May 2026

View topic

Count: 528

Article ‘Count’ for Clinical Sciences.

Journal Count Share
1 0.06
Ultrasmall Surface-Charge-Modified Tantalum Oxide Nanoparticles for the Assessment of Articular Cartilage Using Contrast-Enhanced Computed Tomography 0.06
2 0.51
Charge-Engineered Microparticles for Targeted Delivery of RhoA Activator to Nucleus Pulposus 0.13
Hepatic adaptation to chronic metabolic stress primes tumorigenesis 0.39
1 0.06
Enzymatically Switchable Pyroptosis-Inducing Polymer Conjugate to Coordinate Host Immune Responses in Cancer Immunotherapy 0.06
2 0.93
Associations of body mass index, waist circumference, and weight-adjusted waist index with body composition and biomarkers: A multinational pooled analysis 0.11
Empirical Dietary Index for Lower Urate Levels and Risk of Gout: Evidence From Cohort Studies 0.82
1 1.00
Longitudinal study of dietary intake and risk of persistent tinnitus in 2 large independent cohorts of women 1.00
7 2.14
Identification of de novo variants from parent-proband duos via long-read sequencing 0.04
Low population penetrance of variants associated with inherited retinal degenerations 0.89
Transcriptome-wide outlier approach identifies individuals with minor spliceopathies 0.12
Phenome-wide association study of male and female sex chromosome trisomies in 1.5 million participants of MVP, FinnGen, and UK Biobank 0.09
Extracting and calibrating evidence of variant pathogenicity from population biobank data 0.75
Exploring depression treatment response by using polygenic risk scoring across diverse populations 0.20
Genomic rare variant mechanisms for congenital cardiac laterality defect: A digenic model approach 0.05
1 0.09
Survival outcomes after inadvertent surgery in low-risk early-stage cervical cancer 0.09
1 0.67
Stromal SRD5A2 promotes prostate growth through WNT5A-LEF1-IGF1 signaling in benign prostatic hyperplasia 0.67
7 1.10
Effects of an early restrictive versus liberal fluid strategy on long-term patient-centered outcomes in sepsis-induced hypotension (SHAMROC): an open-label, randomized controlled trial 0.06
Cost-Effectiveness of Community Tuberculosis Screening in South Africa 0.64
The Effectiveness of Isoniazid Preventive Treatment among Contacts of Multidrug-Resistant Tuberculosis: A Systematic Review and Individual-Participant Meta-Analysis. 0.08
Physiological Consequences of Breathing Effort According to the Mode of Ventilation During Acute Hypoxemic Respiratory Failure. 0.03
Biologic Mechanisms Underlying the Heterogeneous Response to Tight Glycemic Control among Differentially Inflamed Patients in the HALF-PINT Trial. 0.13
Differences in Arterial Blood Gas Testing by Race and Sex across 161 U.S. Hospitals in Four Electronic Health Record Databases 0.05
Elastance May Determine the Neuromuscular Blockade Effect on Mortality in Acute Respiratory Distress Syndrome 0.11
6 3.55
Preoperative Olanzapine and Quality of Recovery after Ambulatory Surgery: A Randomized Clinical Trial. 0.13
Perspectives of children, parents and health care providers on outcomes following anesthesia for surgery:: An international mixed methods stakeholder engagement study from the Pediatric Perioperative Outcomes Group. 0.06
Changes in intraoperative rocuronium dosing following the introduction of sugammadex and association with postoperative respiratory complications: A retrospective cohort study. 0.73
Nitric Oxide to Reduce Acute Kidney Injury in Patients with Pre-existing Endothelial Dysfunction Requiring Prolonged Cardiopulmonary Bypass: A Randomized Clinical Trial. 0.86
Head Strikes Among Perioperative Personnel in the United States: A Mixed Methods Study. 0.78
A Randomized Controlled Trial of Intraoperative Ketamine for Acute Postsurgical Pain after Breast Cancer Surgery: The Moderating Effect of Baseline Temporal Summation of Pain. 1.00
5 2.09
Characterizing Emergency Department Visits to Pediatric Hospitals After Local Disaster Declarations 1.00
Capabilities Among Emergency Departments Participating in a Nationwide Quality Improvement Learning Collaborative to Care for Patients With Opioid Use Disorder: 2020 to 2024 0.10
Treatment of Opioid Use Disorder Across a National Emergency Department Practice Improvement Network 0.13
Development of a Unified Geriatric Emergency Department Database, 2022 0.80
Adoption of Boarding in Inpatient Hallways During Emergency Department Crowding 0.07
1 0.17
Primary Care Patients With Opioid Use Disorder Symptoms: Initiation and Engagement in Treatment With Medicine 0.17
5 1.78
Firearm Acquisition and New Exposure to Household Firearms After the Initial Pandemic Purchasing Surge: Results From the 2024 National Firearms Survey. 0.50
Effect of Social Vulnerability on Efficacy of Bariatric Surgery Versus Medical and Lifestyle Intervention for Type 2 Diabetes: Analysis of the ARMMS-T2D Consortium of Randomized Trials. 0.43
Step Accumulation Patterns and Risk for Cardiovascular Events and Mortality Among Suboptimally Active Adults. 0.17
Association Between Body Composition and Cardiometabolic Outcomes : A Prospective Cohort Study. 0.31
Medications and Risk for Microscopic Colitis: A Nationwide Study of Older Adults in Sweden. 0.38
5 1.88
Longitudinal Phenotypic Trajectories in GNAO1-Related Disorders: Defining Disease Progression and Clinical Profiles 0.08
Intranasal Seletracetam in a Patient with Reading Epilepsy: First‐in‐Human Use to Prevent Reflex Seizures 0.10
A Digital Measure of Eye Movements During Reading Sensitively Captures Oculomotor and Speech Dysfunction, Early Changes, and Disease Progression in Ataxias 1.00
Midlife Steroid‐Binding Globulin Levels and iIn Vivo/i Neuroimaging Measures of Tau in Older Men and Women 0.48
Clinical, Prognostic, and Longitudinal Functional and Neuropsychological Features of West Nile Virus Neuroinvasive Disease in the United States: A Systematic Review and Meta‐Analysis 0.23
7 2.31
Comparative Effectiveness of Single Versus Bilateral Lung Transplantation in Dually Listed Recipients: A National Target Trial. 0.07
Practice, Policy, and Research Recommendations to Improve Decision-Making about Surgery for People Living with Dementia: A Delphi Panel Consensus. 0.60
Rare and Tricky: The Relationship Between Hospital Trauma Volume and Delay in Surgical Intervention in Blunt Intestinal Injury. 1.00
A Multicenter Double-blind Randomized Sham-controlled Trial Assessing the EndoBarrier Duodenal-jejunal Bypass Liner for the Treatment of Poorly Controlled type 2 Diabetes Mellitus with Concomitant Obesity: The ENDO Trial. 0.20
Association of Prophylactic Antibiotic Guideline Non-Adherence with Surgical Site Infections in Patients Receiving Perioperative Vancomycin: Results from a Multi-Institutional Combined NSQIP and MPOG Registry. 0.09
Postoperative Opioid Prescribing Among Adults with Disabilities After a Medicare Opioid Limit Policy. 0.10
Prophylactic Antibiotic use and Outcomes in Infants Undergoing Pyloromyotomy: A Multicenter Propensity Matched Cohort Analysis. 0.25
4 0.99
Deep profiling of lupus nephritis kidneys reveals dynamic changes in myeloid cells associated with disease progression 0.26
SLE classification criteria item relationships: implications on SLE as a disease entity 0.20
Antimitochondrial antibodies in systemic sclerosis target enteric neurons and are associated with GI dysmotility 0.50
Exploring the limit of image resolution for human expert classification of vascular ultrasound images in giant cell arteritis and healthy subjects: the GCA-US-AI project 0.03
1 0.60
Trends in Opioids and Non-Pharmacologic Pain Management among U.S. Cancer Survivors, 2011–2020 0.60
14 6.23
T cell plasticity in systemic lupus erythematosus revealed by large‐scale T cell receptor repertoire and transcriptome studies 0.15
Differences in SARS‐CoV‐2 antigen persistence in individuals with systemic autoimmune rheumatic diseases compared to the general population: A RECOVER‐Adult Cohort Study 0.83
Inferring rheumatoid arthritis disease activity status from the electronic health records across health systems 0.46
Deficiency of AP1M2 causes a new autoinflammatory disease with colitis 0.06
Longitudinal Changes in Serum Urate Levels from Pre‐menopause through Post‐menopause: Interrupted Time‐Series Analyses 0.45
Interleukin‐23 receptor deficiency in podocytes averts the development of lupus nephritis. 0.93
Skin biopsies enhance prediction of clinical trajectory in diffuse cutaneous systemic sclerosis 0.00
Distinct Cancer Risk Profiles in Patients with Systemic Sclerosis with Autoantibody Stratification 0.80
Risk of serious infection in patients with rheumatoid arthritis‐associated interstitial lung disease or bronchiectasis: A comparative cohort study 0.69
Hand Swelling and Other Non–Raynaud Phenomenon Symptoms as the Initial Presentation of Systemic Sclerosis: Prevalence and Clinical Associations in Two scpUS/scp Cohorts 0.03
ADAM9 promotes glycolysis in Th17 cells and autoimmunity through activation of IGF‐1 signaling 0.79
Three‐Year Outcomes and Latent Class Trajectory Analysis of the Childhood Arthritis and Rheumatology Research Alliance Polyarticular scpJIA/scp Consensus Treatment Plans Study 0.22
Complex Regulatory Interactions at scpiGDF5/i/scp Shape Joint Morphology and Osteoarthritis Disease Risk 0.77
Three‐Year Results of Tapering Tumor Necrosis Factor Inhibitor to Withdrawal Compared to Stable Tumor Necrosis Factor Inhibitor Among Patients With Rheumatoid Arthritis in Sustained Remission: A Multicenter Randomized Trial 0.05
1 0.64
Single-cell and clonal analysis of AL amyloidosis plasma cells and their bone marrow microenvironment. 0.64
4 0.19
Biosignatures of cognitive basic symptoms mark a distinct neurodevelopmental pathway to schizophrenia 0.02
Predictive models for ataxia progression and conversion in spinocerebellar ataxia type 1 and 3 0.03
Connectivity as a universal predictor of tau progression in atypical Alzheimer’s disease 0.07
Cognitive loss after brain trauma results from sex-specific activation of synaptic pruning processes 0.08
1 0.07
Impact of bariatric surgery on patients with chronic kidney disease and severe obesity: multiple-linked population-based cohort study 0.07
1 0.06
Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct patterns and potential markers of progression 0.06
4 1.11
Systematic discovery of pro- and anti-HIV host factors in primary human CD4+ T cells 0.00
Mining the CD4 antigen repertoire for next-generation tuberculosis vaccines 0.75
A generative deep learning approach to de novo antibiotic design 0.24
Bronze Age Yersinia pestis genome from sheep sheds light on hosts and evolution of a prehistoric plague lineage 0.11
1 1.00
A prophage intercepts pathogenic activity of infecting phage for defense 1.00
1 0.07
Therapeutic remodeling of the ceramide backbone prevents kidney injury 0.07
2 0.40
Associations between Prior Lung Diseases and Risk of Lung Cancer in Populations With No Smoking History: A Systematic Review and Meta-Analysis 0.33
Covert triage during the COVID-19 pandemic: A qualitative analysis of rationing in intensive care 0.07
4 0.95
N-Palmitoyl Glutamine Is a Candidate Mediator of Cardiorespiratory Fitness. 0.51
High-Dose vs. Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults: The FLUNITY-HD Prespecified Pooled Analysis. 0.07
Randomized Controlled Trial of Mechanical Thrombectomy With Anticoagulation Versus Anticoagulation Alone for Acute Intermediate-High Risk Pulmonary Embolism: Primary Outcomes from the STORM-PE Trial. 0.29
Subclinical Primary Aldosteronism and Major Adverse Cardiovascular Events: A Longitudinal Population-Based Cohort Study. 0.08
16 4.60
Impact of Procalcitonin Testing on Antibiotic Use in Patients Hospitalized With Community-Acquired Pneumonia: A Multi-Hospital Cohort Study 0.08
Mapping Hospitals That Treat Severe Malaria Cases in the United States: Evidence to Inform Health Systems Strategies for Intravenous Artesunate Supply 0.45
A 48-Week, Randomized Controlled Trial of Doravirine for Individuals With HIV and Obesity on Integrase Inhibitors and Tenofovir Alafenamide: The Do IT Study (ACTG A5391) 0.13
Patterns of HIV-1 Viral Load Suppression and Drug Resistance During the Dolutegravir Transition: A Population-based Longitudinal Study 0.02
Implementing a Program of Comprehensive Tuberculosis Preventive Treatment: Safety, Effectiveness, and Acceptability of Moxifloxacin or Bedaquiline Use for Contacts Exposed to Drug-Resistant Strains 0.07
Pregnant women with MDR/RR-TB and the all-oral 6-month regimen: experiences from a patient series in South Africa 0.06
The Bounce-Back Effect: What Happens After Cessation of Low-Dose Semaglutide in People with HIV 0.22
Integrase Strand Transfer Inhibitors for Treatment-experienced Young Adults With Perinatal HIV in the US: Immunologic, Virologic, and Anthropometric Outcomes 0.50
Long-term clinical, immunologic, and viral reservoir outcomes in children treated with VRC01LS and 10-1074 monoclonal antibodies in the Tatelo Study 0.64
HIV Resistance to Dolutegravir Varies With Coadministered Agents 0.07
Increasing HIV Testing During Gonorrhea and Chlamydia Evaluations in Urgent Care and Emergency Departments: A Large Health System Initiative 0.05
Characterizing Treatment Adherence Trajectories in the endTB Multisite Cohort of Drug-Resistant Tuberculosis Patients: An Application of Group-Based Trajectory Modeling 0.11
Clinical consequences of delaying implementation of long-acting antiretroviral therapy for people with HIV and persistent viremia in the US 0.71
Protracted SARS-CoV-2 Infection in B-cell Depleted Patients: Immunologic andiral Characteristics and Response to Dual and Extended Antiviral Therapy 0.97
Phase 2 Trial of Long-Acting Cabotegravir and VRC07-523LS for Viral Suppression in Adults with HIV-1: ACTG A5357 0.14
Effect of Pitavastatin on Epigenetic Aging Biomarkers in People With HIV: Pilot Substudy of the REPRIEVE Trial 0.38
7 1.32
Comparison of Blood Culture Contamination Rates Between Initial Central Venous Puncture and Catheter Hub Sampling 0.06
Artificial Intelligence Algorithm to Monitor Inspiratory Muscle Effort and Patient-Ventilator Dyssynchrony During Mechanical Ventilation 0.11
Effects of Early Versus Delayed Mechanical Thrombectomy on Outcomes in Intermediate-Risk Acute Pulmonary Embolism. 0.18
Temperature Control After In-Hospital Cardiac Arrest: Outcomes From the Discover In-Hospital Cardiac Arrest Cohort. 0.04
Location of In-Hospital Cardiac Arrest: An Updated Analysis of Epidemiology, Emergency Response, and Outcomes. 0.09
Association Between Hospital-Level Volume of Extracorporeal Membrane Oxygenation and Complications: A Clustered, Mixed-Effect Analysis of the Extracorporeal Life Support Organization Registry. 0.13
Variability in Venovenous Extracorporeal Membrane Oxygenation Candidacy Decision-Making: An International Survey. 0.71
1 0.06
Asymmetric lateral habenula function and peripheral neural mechanisms in regulating itch-evoked scratching 0.06
1 0.03
Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics analysis of progression from Barrett’s Esophagus to adenocarcinoma 0.03
12 4.54
Comparative Effectiveness of Tirzepatide Versus Dulaglutide or Semaglutide on Major Cardiovascular Events in Type 2 Diabetes and Cardiovascular Disease: Insights From Two Target-Trial Emulations. 0.96
Gout-Related Medication Use After Initiating Sodium-Glucose Cotransporter 2 Inhibitors in Patients With Gout and Type 2 Diabetes: Population-Based Target Trial Emulation Studies. 0.50
Global, Regional, and National Estimates of Undiagnosed Diabetes in Adults: Findings From the 2025 IDF Diabetes Atlas. 0.17
Medication Adherence in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) 0.07
Novel Phenotypic Clusters of Youth-Onset Type 2 Diabetes Offer No Added Prognostic Value to Simple Clinical Measures. 0.38
Inflammatory and Insulinemic Dietary Patterns and Risk of Type 2 Diabetes Among Women With a History of Gestational Diabetes Mellitus: A Prospective Study of 84,174 Person-Years of Follow-up. 0.34
Sodium-Glucose Cotransporter-2 Inhibitors, Glucagon-Like Peptide-1 Receptor Agonists, and Frailty Progression in Older Adults With Type 2 Diabetes. 0.92
Impact of Baseline GLP-1 Receptor Agonist Use on Albuminuria Reduction and Safety With Simultaneous Initiation of Finerenone and Empagliflozin in Type 2 Diabetes and Chronic Kidney Disease (CONFIDENCE Trial). 0.07
Plasma Metabolome, Long-term Body Weight Change, and Type 2 Diabetes in U.S. Individuals. 0.95
Use of the Omnipod 5 Automated Insulin Delivery System Activity Feature Reduces Insulin Delivery and Attenuates the Drop in Glycemia Associated With Exercise in a Randomized Controlled Trial. 0.05
A Multimodal Predictive Model for Chronic Kidney Disease and Its Association With Vascular Complications in Patients With Type 2 Diabetes: Model Development and Validation Study in South Korea and the U.K. 0.04
Impaired Rest-Activity Rhythm Characteristics Predict Higher Risk of Incident Type 2 Diabetes in UK Biobank Participants. 0.11
1 0.09
Associations of gestational and childhood urinary triclosan concentrations with atopic and allergic symptoms in Health Outcomes and Measures of the Environment (HOME) Study participants ages 1-12 years. 0.09
2 0.30
Association of Exposure to Phthalates and Substitutes with Infection Risk Among U.S. Children 0.20
Integrated culture-based and metagenomic profiling of airborne and surface-deposited bacterial communities in residential environments 0.10
3 1.17
Exposure to organophosphate esters and trajectories of gestational weight gain: A large prospective cohort study 0.25
Gestational phthalate levels and biomarkers of aging in infants and children from New York City 0.10
Association of urinary phthalate metabolite concentrations with inflammatory biomarker levels among pregnant women 0.82
1 0.63
Long-Term Exposure to Multiple Environmental Factors and Late-Life Cognitive Decline 0.63
4 0.44
Optimal serum potassium concentrations in heart failure: an individual patient data meta-analysis 0.22
Volume vs intensity of physical activity and risk of cardiovascular and non-cardiovascular chronic diseases 0.04
C-reactive protein and cardiovascular risk in the general population 0.09
Cardiac amyloidosis detection from a single echocardiographic video clip: a novel artificial intelligence-based screening tool 0.09
1 0.04
Duration of Androgen Suppression with Postoperative Radiotherapy (DADSPORT) for Nonmetastatic Prostate Cancer: A Collaborative Systematic Review and Meta-analysis of Aggregate Data 0.04
4 0.61
Recommendations for the Evaluation and Management of Inflammatory Bowel Disease With Irritable Bowel Syndrome–Like Symptoms: A Joint Rome Foundation and International Organization for the Study of IBD (IOIBD) Consensus 0.08
Identification of a Druggable Target That Predicts Postoperative Crohn’s Disease Recurrence 0.03
The Prevalence and Burden of Avoidant/Restrictive Food Intake Disorder (ARFID) Symptoms in Adults with Disorders of Gut-Brain Interaction: A Population-Based Study 0.20
Low FODMAP diet improves colonic barrier function and mast cell activation in patients with IBS-D: A mechanistic trial 0.31
8 0.75
Two-step clinical care pathway to predict MASLD-related advanced fibrosis and long-term outcomes in type 2 diabetes 0.02
Targeting MLCK1 uncouples immune checkpoint inhibitor-induced colitis from antitumour immunity 0.06
TL1A-activated T cells remodel the rectal mucosa in patients with Crohn’s disease with perianal fistulising disease 0.07
Global prevalence of self-reported non-coeliac gluten and wheat sensitivity: a systematic review and meta-analysis 0.04
Thrombospondin-2 is a performant biomarker of at-risk MASH and advanced MASH fibrosis in a large multicentre European cohort 0.03
Mitochondrial dysfunction drives basal cell hyperplasia in eosinophilic oesophagitis 0.10
Lifestyle factors, genetic susceptibility and risk of incident diverticulitis: an integrated analysis of four prospective cohort studies and electronic health records-linked biobank 0.42
Non-invasive risk-based surveillance of hepatocellular carcinoma in patients with metabolic dysfunction-associated steatotic liver disease 0.03
6 0.61
OCE-205, a selective V1a receptor mixed agonist-antagonist, for the treatment of hepatorenal syndrome-acute kidney injury: A phase 2 randomized trial. 0.14
ECM1 produced by hepatic stellate cells serves as a gatekeeper of liver homeostasis in hepatic fibrosis. 0.05
Head-to-head comparison between vibration-controlled transient elastography and histology in predicting liver-related events due to metabolic dysfunction-associated steatotic liver disease. 0.03
HBV induces liver fibrosis through the generation of reactive oxygen species in a pyruvate-dependent manner. 0.31
Association between longitudinal weight change and clinical outcome in individuals with MASLD. 0.02
Natural history and development of a novel composite endpoint in patients with alcohol-associated Hepatitis: Data from a prospective multicenter study. 0.06
10 2.83
Dietary sulfur amino acids enhance anti-tumor immunity in colon cancer via an NKT cell-XCL1-cDC1 circuit 0.59
Skin inflammation and itch response are independently regulated by distinct nociceptor subsets 0.12
Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques 0.04
Multiplexed antigen panel analysis identifies B cell phenotype and receptor genetic contributions to antibody breadth 0.03
Multiomic analysis of ART-interruption cohorts identifies cell-extrinsic and -intrinsic mechanisms driving lymphocyte-mediated control of HIV rebound 0.03
HIV broadly neutralizing antibody escape dynamics drive the outcome of AAV-vectored immunotherapy in humanized mice 0.53
Local antibody feedback enforces a checkpoint on affinity maturation in the germinal center and promotes epitope spreading 0.38
A myeloid Tet2-IL-1β axis modulates intestinal inflammation by restricting catecholaminergic stimulation of enterochromaffin cell differentiation 0.18
S. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis 0.70
Multi-scaled transcriptomics of chronically inflamed nasal epithelium reveals immune-epithelial dynamics and tissue remodeling in nasal polyp formation 0.23
1 0.17
Quantifying disruptions to tuberculosis case detection in Brazilian states during the COVID-19 pandemic 0.17
3 1.02
Testosterone Treatment in Prostate Cancer Survivors With Hypogonadism 0.92
Extended-Release vs Sublingual Buprenorphine in Pregnancy Through 12 Months Post Partum 0.05
High-Dose vs Standard-Dose Influenza Vaccine in Older Adults With Diabetes 0.05
6 2.85
HIV Preexposure Prophylaxis Uptake Among US Youth in a National Claims Database 0.67
Sleep Health Dimensions From Wearables and Transdiagnostic Mental Health in Young Adolescents 0.20
Clinical Signs Associated With Mortality and Sepsis in Young Infants 0.56
Artificial Intelligence Length-of-Stay Forecasting and Pediatric Surgical Capacity 1.00
Optimal Dose of Intranasal Midazolam for Procedural Sedation in Children 0.08
Firearm Laws and Pediatric Mortality in the US 0.33
5 1.51
Spirituality and Harmful or Hazardous Alcohol and Other Drug Use 0.73
Yoga for Opioid Withdrawal and Autonomic Regulation 0.10
Contrasting Risk Profiles for Suicide Attempt and Suicide Using Danish Registers and Genetic Data. 0.02
Heart Rate Variability Biofeedback for Substance Use Disorder 0.60
Polygenic Risk, Psychopathology, and Personalized Functional Brain Network Topography in Adolescence 0.06
6 1.25
Implementation and Effectiveness of an Enhanced Recovery Protocol for Children Undergoing Surgery 0.02
Evolving Inguinal Hernia Repair Practice at the Veterans Health Administration 0.25
Bed Capacity and Utilization at Hospitals With Trauma Centers 0.17
Recurrence in Patients With Lymph Node-Negative Pancreatic Neuroendocrine Tumors 0.17
Preoperative Hemoglobin A1C, Glycemic Status, and Postoperative Outcomes in General Surgery 0.25
Allocation Out of Sequence in Lung Transplant 0.40
9 1.95
Amoxicillin-Clavulanate vs Amoxicillin for Acute Sinusitis in Adults 0.38
Intrawound Tobramycin Plus Vancomycin to Prevent Surgical Site Infection in Tibial Fractures 0.06
National Estimates of Pediatric Sepsis in US Hospitals Using Clinical Data 0.03
Treatment for Brain Metastases With Stereotactic Radiation vs Hippocampal-Avoidance Whole Brain Radiation 0.68
Minor Papillotomy for Treatment of Idiopathic Acute Pancreatitis With Pancreas Divisum 0.03
Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score 0.01
Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction 0.69
Bivalent RSV Prefusion F Protein–Based Vaccine for Preventing Cardiovascular Hospitalizations in Older Adults 0.06
Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function 0.03
10 5.28
Evaluating the Utility of Staphylococcus aureus Nasal Screening in Preventing Surgical Site Infections in Elective Orthopaedic Surgery: A Propensity-Matched Analysis. 0.50
Lower Trapezius Transfer at the Time of Reverse Shoulder Arthroplasty with an Allograft-Prosthetic Composite Can Restore External Rotation. 0.14
Survivorship of Femoroacetabular Impingement Surgery at Mean 10-Year Follow-up: A Prospective, Multicenter Cohort Study. 0.22
The Prevalence of Subtalar Arthritis Following Pilon Fractures. 0.97
The Ultrasound-Assisted Patellar Glide Test: A Novel Examination Method for Quantifying Patellar Instability 1.00
Risk Factors for Nonunion Following Lateral Locked Plating of Distal Femoral Fractures 0.75
Assessment of the Mechanical Performance of an Affordable External Fixator (AEFIX) Designed for Resource-Limited Settings. 0.52
Distinct 3-Dimensional Morphologies of Arthritic Knee Anatomy Exist: CT-Based Phenotyping Offers Outlier Detection in Total Knee Arthroplasty. 0.11
Impact of Childhood Obesity on Capital Femoral Epiphysis Morphology: A Large-Scale, Automated 3D-CT Study and Potential Implications for SCFE Pathogenesis. 1.00
High Failure Rates of Polyethylene Glenoid Components in Stemless Anatomic Total Shoulder Arthroplasty for Primary and Secondary OA. 0.07
9 2.43
The use of semaglutide as an add-on therapy in patients with latent autoimmune diabetes in adults 0.03
Implementation of a Spanish-Language, Direct-to-Patient Primary Aldosteronism Testing Program 0.87
MECP2 Rare Variants in Boys With Central Precocious Puberty 0.50
Rapid and Sustained Response of Biochemically Uncontrolled Acromegaly to Once-Daily Oral Paltusotine Treatment 0.06
The Relation Between Systemic Inflammation and the Menopause Transition: The Study of Women's Health Across the Nation 0.09
Association of IGF-1 levels with height from childhood to adulthood: An observational and Mendelian randomization study 0.04
Trends of Diabetes in Youth (TrenDY) during COVID-19 across the United States 0.08
Integrative Machine Learning Approach for Predicting Resistance to First-Generation Receptor Ligands in Acromegaly 0.67
Maternal Thyroid Function During Pregnancy and Early Adolescent Regional Differences in Cerebral Gray Matter Morphology 0.10
8 2.13
Multiomic analyses delineate human neuroendocrine tumor cell states in relation to normal enteroendocrine cell ontogeny 0.67
Smac mimetic combined with eCD4-Ig reverses latency without reducing SHIV reservoirs in rhesus macaques 0.03
Immune correlates of HIV-1 rebound during broadly neutralizing antibody treatment in young children 0.67
Variation in antiviral immunity and inflammation pathways precedes HIV-1 infection in a high-risk African cohort 0.02
Plasma chondroitin sulfate predicts the effectiveness of fluid resuscitation strategies in patients with sepsis 0.26
Efficacy and safety of a therapeutic humanized FSH–blocking antibody in obesity and Alzheimer’s disease models 0.02
Purinergic signaling modulates CD4+ T cells with cytotoxic potential during Trypanosoma cruzi infection 0.13
Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis 0.34
4 0.98
Efficacy and Safety of Anselamimab in Immunoglobulin Light Chain Amyloidosis: Results From the Randomized CARES Trials 0.06
Randomized Phase II Trial of Pazopanib Versus Placebo in Patients With Advanced Extrapancreatic Neuroendocrine Tumors (Alliance A021202). 0.07
Stereotactic Radiosurgery in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases: A Multi-Institutional, Phase II, Prospective Clinical Trial. 0.80
Phase II (Alliance A091802) Randomized Trial of Avelumab Plus Cetuximab Versus Avelumab Alone in Advanced Cutaneous Squamous Cell Carcinoma. 0.05
4 1.05
Immune profiling links autoimmune hepatitis to human herpesvirus 6 and relaxin receptor antigens 0.04
Inflammation rewires the enteric nervous system through neurogenic monocyte recruitment 0.02
Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies 0.02
Breast cancer gene-1 (BRCA1) potentiates maladaptive repair after kidney injury 0.97
2 0.06
Prognostic value of liver stiffness measurement vs. biochemical response in primary biliary cholangitis 0.05
Effect of Hypertension on Long-term Adverse Clinical Outcomes and Liver Fibrosis Progression in MASLD 0.01
15 3.27
A New Type of Nonsuppressible Viremia Produced by HIV-Infected Macrophage 0.14
<atl>A Genomic Analysis of Community-Associated iC. Difficile/i Infection Demonstrates Integration With National and International Strain Clusters and Limited Direct Transmission</atl> 0.40
Immune-Based Cytokine Signatures of Prolonged Pandemic-Associated Chilblains 0.14
Frailty in People with HIV is Linked to Inflammation, Bone Health, and T cell Exhaustion 0.18
Dynamics of Intact and Defective Human Immunodeficiency Virus Type 1 (HIV-1) Proviruses During Decades of Suppressive Antiretroviral Treatment in Young Adults With Perinatal HIV 0.38
Human Immunodeficiency Virus–Associated Proteomic Signature of Myocardial Fibrosis and Incident Heart Failure 0.05
Douching Is Associated With Dysregulated Rectal Mucosal Immunity in Sexual Minority Men 0.08
A threshold in anti-EBNA-1 antibody titers distinguishes salivary EBV shedders from non-shedders 0.96
Long-Acting Antiretroviral Therapy for Breastfeeding Women With HIV Experiencing Barriers to Adherence in Zimbabwe: Modeling Clinical Impact and Cost-effectiveness 0.46
Trichomonas vaginalis Among Cisgender Women Taking Doxycycline Postexposure Prophylaxis 0.03
Relative Effectiveness of High-Dose Versus Standard-Dose Influenza Vaccination Against Hospitalizations and Deaths According to Frailty Score: A Post Hoc Analysis of the DANFLU-1 Randomized Trial 0.10
Comparability of gastrointestinal microbiome and bile acid profiles in patients with first or multiply recurrent iClostridioides difficile/i infection 0.06
Antiviral Monocytes Increase Prior to Detectable HIV-1 Rebound Viremia 0.09
Global trends in antibiotic expenditure: analysis of pharmaceutical sales data, 2013 to 2023 0.14
Secreted Chorismate Mutase: A Novel Prognostic Factor in Mycobacterium intracellulare Pulmonary Disease 0.06
4 1.04
Primary Neural Degeneration after Cochlear Implantation: Histological and Electrophysiological Evidence from a Mouse Model 0.08
Parallel Age-Related Cochlear Neural Degeneration and Cortical Gain Adaptation in Normal-Hearing Humans 0.11
Distributed fMRI Patterns Coupled to Low-Frequency Cardiorespiratory Dynamics Provide Markers of Aging 0.07
Neural and Behavioral Markers of Negative Symptoms and Cognitive Impairment in Patients with Psychosis 0.78
2 1.09
Regulation of basal and tumour necrosis factor α‐induced fibroblast gene expression by peptidylarginine deiminase 2 1.00
Effect of varying driving pressure and respiratory rate on ventilator‐induced lung injury in healthy and injured lungs: An experimental animal study 0.09
3 1.18
Randomized, Sham-Controlled Trial of Intraoperative Ticagrelor Removal to Reduce Perioperative Bleeding 0.08
Stroke After Aortic Arch Surgery with Short Circulatory Arrest Times: The Role of Cerebral Perfusion Strategies 0.43
Association Between Subclavian Vein Patency and Health-Related Quality of Life Outcomes Among Patients with Venous Thoracic Outlet Syndrome 0.67
1 0.04
Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-Analysis 0.04
16 4.90
Prognostic determinants of early and late relapse in cutaneous squamous cell carcinoma: a multicenter retrospective cohort study 0.08
Analysis of Medicolegal Precedents of Neuromodulators and Soft-Tissue Fillers 2008-2025 0.21
Topical vs Systemic Corticosteroids for DRESS Syndrome: Real-World Outcomes from a Multi-Center Retrospective Cohort 0.52
Hyperkalemia incidence in females over 45 years old on spironolactone for dermatologic conditions: A retrospective cohort study 0.70
Efficacy and safety of sodium-glucose cotransporter-2 inhibitors in patients with psoriasis and comorbid type 2 diabetes: A population-based target trial emulation 0.92
Safety and tolerability of combination oral spironolactone and low-dose oral minoxidil for hair loss in adult females: A retrospective cohort study 0.67
Bimekizumab demonstrated a favorable safety profile and high levels of efficacy with up to 2 years of treatment in patients with moderate to severe hidradenitis suppurativa: Pooled results from two phase 3 randomized, controlled trials and their open-label extension 0.06
Efficacy and Safety of Ruxolitinib Cream in Patients With Mild to Moderate Hidradenitis Suppurativa: Results From a Randomized, Double-Blind, Vehicle-Controlled Phase 2 Study 0.20
Clinical Practice Guidelines for the Management of Basal Cell Carcinoma in Gorlin Syndrome 0.02
A randomized, double-blind, placebo-controlled phase 2 study of eltrekibart, a novel septa-specific monoclonal antibody to CXCR1/2 ligands, in adults with hidradenitis suppurativa 0.10
Efficacy and Safety of Cosibelimab in Advanced Cutaneous Squamous Cell Carcinoma: Results From a Pivotal Open-label Study With a Median Follow-up of ≥2 Years 0.04
Impact of Immunosuppression on Cutaneous Squamous Cell Carcinoma Outcomes 0.12
Establishment of standardized definitions and a core set of outcome characteristics following hidradenitis suppurativa surgery developed by an expert Delphi consensus 0.03
The Effect of Isotretinoin Treatment for Acne Vulgaris on Height in Adolescents: A Retrospective Cohort Study Using the Rochester Epidemiology Project 0.17
Type 2 Immunity Links Eczematous and Lichenoid Eruptions Caused by Immune Checkpoint Inhibitors 1.00
Satellitosis/in-transit metastasis in cutaneous squamous cell carcinoma: Risk factors and the prognostic significance 0.07
2 0.98
Actifensin Evolution in the Human Oral Cavity over the Past 100,000 Years 0.04
Eggerthella lenta Produces a Cryptic Pro-inflammatory Lipid 0.94
10 2.56
Mechanical Thrombectomy and Catheter-Directed Thrombolysis in Acute Pulmonary Embolism 0.86
High-Dose vs Standard-Dose Influenza Vaccine in Chronic Kidney Disease The DANFLU-2 Trial Subgroup Analysis 0.06
Risk of Hyperkalemia With Empagliflozin, Finerenone, or Both: Secondary Analysis of CONFIDENCE Randomized Trial 0.07
Myocardial Amyloid Burden in Transthyretin Amyloidosis 0.04
Frailty Scale Captures Multidimensional Vulnerability and Predicts Mortality in Heart Failure 0.01
Effect of Acoramidis on Recurrent and Cumulative Cardiovascular Outcomes in ATTR-CM: Exploratory Analysis from ATTRibute-CM 0.05
Timing of Mortality Benefit in Outcomes Trials in Transthyretin Amyloidosis 0.57
Outcomes of Percutaneous Mechanical Aspiration in Right-Sided Infective Endocarditis A Multicenter Registry 0.05
Adiposity-Related Anthropometrics and Clinical Outcomes in Heart Failure With Mildly Reduced or Preserved Ejection Fraction A Participant-Level Pooled Analysis of Randomized Clinical Trials 0.40
Effects of Vutrisiran on Cardiac Function and Outcomes in Patients With Transthyretin Amyloidosis With Cardiomyopathy 0.46
19 10.45
Cognitive Trajectories After Major Surgery in Older Adults and Factors Associated With Severe Decline 0.83
Feasibility of a Multicomponent Frailty Intervention During Post‐Acute Rehabilitation in Skilled Nursing Facilities 1.00
Exploring Current Emergency Medical Services Approaches to Manage Agitated Older Adult Patients: An Analysis of Statewide Protocols 0.20
Primary Care Practitioners' Approaches to Deprescribing Opioids for Older Adults With Chronic Pain: A Qualitative Analysis 0.80
The Bright Side of Life: Optimism and Risk of Dementia 0.74
<atl>Quality of Medicare Skilled Home Health for People Living With Dementia in the scpUS/scp : National Patterns and Implications</atl> 0.13
Association of Geriatric Consult Services With Geriatric Processes of Care and Clinical Outcomes in US Trauma Centers 0.20
“By the Skin of Our Teeth”: U.S. Hospital, Regional, and State Experiences of Scarcity During the COVID-19 Pandemic 0.13
Functional Decline and Loss of Independence After Traumatic Injury in Older Adults With Dementia 0.81
Perioperative Optimization of Frail Older Adults Undergoing Elective Colorectal Surgery 1.00
Role and Expectations of Family Caregivers in Hospital at Home in the scpUS/scp and Canada 0.17
A Qualitative Study of Health Priorities of People With Dementia and Care Partners in Emergency Department and Hospital Care in a Public Safety‐Net Setting 0.25
Patients With Dementia Undergoing High‐Risk Inpatient Surgery Have Poor Outcomes 0.73
Age-Related Changes in the Clinical Picture of Long COVID 0.11
Patterns of Benzodiazepines and Hypnotic Drugs Dispensing After Hip Fracture Among Older scpUS/scp Adults Previously on the Drugs 0.13
Can an Innovative Physical Therapy Program Improve Executive Function? A Study Among Veterans With Slow Gait Speed 0.24
Pattern and Associated Factors of Benzodiazepine Discontinuation Among Older Adults Following Hospitalization 1.00
Treatment Burden Among Older Adults in the United States, 2022 1.00
Use of Nursing Homes Among Medicaid Beneficiaries Newly Diagnosed With Cancer 1.00
3 0.43
Subclinical Primary Aldosteronism and eGFR Decline Over Time. 0.07
High Phosphate and Low Protein Mediate Arterial and Cutaneous Vascular Calcification in CKD Mice. 0.11
Effect of Finerenone on Morbidity and Mortality in CKD. 0.25
6 2.07
FaceAge as a biomarker for prognosis and treatment stratification in large-scale oncology cohort 0.76
Liver fat and clinical outcomes in individuals with stage I-iii Colon or rectal cancer 0.08
Thyroid hormones and epithelial ovarian cancer risk and survival: results from the European Prospective Investigation into Cancer and Nutrition study 0.02
Stereotactic MRI Guided Adaptive Radiotherapy: a pooled analysis of a master prospective trial 1.00
Colon, colorectal, and all cancer incidence increase in the young due to appendix reclassification 0.17
Association of opioid and benzodiazepine coprescribing with adverse events among older adults with cancer 0.05
2 0.15
Genotype-phenotype characteristics and disease progression of FAN1-related karyomegalic tubulointerstitial nephropathy 0.05
Phosphoenolpyruvate carboxykinase 1-mediated cataplerosis is required to maintain mitochondrial fitness and to avoid kidney disease progression 0.11
2 0.73
Alternative start codon selection shapes mitochondrial function and rare human diseases 0.13
A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense 0.61
18 2.05
Anxiety sensitivity and intolerance of uncertainty track distinct neurobehavioral dimensions of avoidance in anxiety-related disorders 0.04
Multiscale characterization of cortical signatures in positive and negative schizotypy: a worldwide ENIGMA study 0.01
Local chemoarchitecture explains widespread lower cortical thickness associated with clinical high risk for psychosis 0.05
Cortical morphometry might predict currently prescribed vs. discontinued medications in bipolar disorder, even after controlling for the cumulative dose effects: An ENIGMA mega-analysis 0.01
Neuroanatomy reflects individual variability in impulsivity in youth 0.01
NADPH oxidase-1 suppression prolongs the antidepressant-like effect of ketamine 0.06
A brain-enriched circRNA blood biomarker can predict response to SSRI antidepressants 0.06
Psychotropic medications and their interactions with subcortical brain volume in bipolar disorder: An ENIGMA mega-analysis 0.03
Structural brain differences associated with panic disorder: an ENIGMA-Anxiety Working Group mega-analysis of 4924 individuals worldwide 0.03
Prediction of postoperative delirium after cardiac surgery by the interplay between preoperative plasma p-tau181 and IL-6 and heart-brain axis related factors: results from the prospective observational study FINDERI 0.02
Structural brain abnormalities and aggression in schizophrenia: mega-analysis of data from 2095 patients and 2861 healthy controls via the ENIGMA consortium 0.02
Regional brain morphology and current antidepressant use: findings from 32 international cohorts from the ENIGMA major depressive disorder working group 0.01
A low frequency damaging SORCS2 variant identified in a family with ADHD compromises receptor stability and quenches activity 0.01
Genetic and epigenetic analysis of plasma glial fibrillary acidic protein (GFAP) levels in PTSD 0.08
Dopaminergic frontostriatal pathways in major depressive disorder and childhood sexual abuse: a multimodal neuroimaging investigation 0.72
Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth 0.01
Projection-specific roles of basolateral amygdala Thy1 neurons in alcohol-induced place preference 0.83
Disease clusters and their genetic determinants following a diagnosis of depression: analyses based on a novel three-dimensional disease network approach 0.04
11 3.63
Feature-specific threat coding in lateral septum guides defensive action 0.65
The DNA virome varies with human genes and environments 0.82
Peripheral immune-inducer dendritic cells drive early-life allergic inflammation 0.00
Integrase anchors viral RNA to the HIV-1 capsid interior 0.11
A prophage-encoded abortive infection protein preserves host and prophage spread 0.84
CD8 T cell stemness precedes post-intervention control of HIV viremia 0.51
Correlates of HIV-1 control after combination immunotherapy 0.00
Rare genetic variants confer a high risk of ADHD and implicate neuronal biology 0.14
Spatial metabolic gradients in the liver and small intestine 0.02
Dietary cysteine enhances intestinal stemness via CD8+ T cell-derived IL-22 0.13
Multi-timescale reinforcement learning in the brain 0.42
1 0.03
Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis 0.03
1 0.43
Proteolysis activity mapping and substrate discovery platform for identifying tumor-activated biosensors 0.43
64 15.89
Regional heterogeneity in phenotypic and genetic associations between bone and brain in humans 0.12
Long-read deep sequencing reveals high rates of multilineage transmission and rapid viral population changes in acute HIV infection 0.03
Disinfection of hospital sink drains enriches pseudomonadota and efflux pump-mediated antibiotic resistance in reestablished biofilms 0.13
Biochemical and brain heterogeneity characterizes psychiatric and non-psychiatric illness 0.03
Early-life Wnt4 expressing colon stromal cells orchestrate lifelong mucosal homeostasis via BMP-driven iNKT cell imprinting 0.46
RNA targeting therapy for a prenatally enriched potassium channel associated with severe childhood epilepsy and premature death 0.33
Face aging rate quantifies change in biological age to predict cancer outcomes 0.90
Acute sleep rebound following sleep restriction is associated with reduced mortality risk 0.25
Multi-kingdom profiling reveals altered gut phage-bacteria-metabolite interactions in MASLD 0.13
Hemostatic Tough Adhesives seal tissue and control hemorrhage 0.70
Daily steps offset risks of sedentary behavior in the All of Us research program 0.17
Pathogenic variants in the cohesin loader subunit MAU2 underlie a distinct Cornelia de Lange Syndrome subtype 0.04
Sustained visceral fat loss is associated with attenuated brain atrophy and improved cognitive function in late midlife 0.12
Multi-omic identification of key transcriptional regulatory programs during endurance exercise training in rats 0.07
Unpacking sources of transmission in HIV prevention trials with deep-sequence pathogen data 0.43
Cortical-limbic circuit dynamics of approach-avoidance conflict in humans 0.08
CAMPER: mechanistic artificial intelligence for designing peptides that target MRSA persisters 0.27
Assessing the micromechanical architecture of joint tissues with speckle rheological microscopy 1.00
The genetic basis of dermatophytosis skin infection susceptibility 0.23
Beta cell-derived cholecystokinin drives obesity-associated pancreatic adenocarcinoma development 0.02
Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis 0.73
A ketogenic diet enhances aerobic exercise adaptation and promotes muscle mitochondrial remodeling in hyperglycemic male mice 0.59
Regional nonsense constraint offers biological and clinical insights into genetic disease 0.03
Using electronic health records to assess the relationship between colonization pressure and nosocomial pathogen acquisition 0.94
Sustained physical activity offers benefits beyond activity volume in chronic disease prevention 0.78
Multicountry genomic analysis underscores regional cholera spread in Africa 0.04
Daratumumab in systemic lupus erythematosus: a single-arm phase 2 trial 0.02
Early detection of aberrant cell fate and repair using circulating progenitor cells in patients with heterotopic ossification 0.23
Geographic spillover of antimicrobial resistance from mass distribution of azithromycin 0.08
Electrographic cue-reactivity co-localizes with accumbens deep brain stimulation in a case of opioid use disorder 0.13
Using the linear references from the pangenome to discover missing autism variants 0.02
Synaptic and intrinsic membrane defects disrupt early neural network dynamics in Down syndrome 0.04
Endothelial cell responses in sepsis are attenuated by targeting truncated procalcitonin 0.03
Vibrio cholerae serotype impacts pathogenicity 1.00
The transcription factor HHEX maintains glucocorticoid levels and protects adrenals from androgen-induced lipid depletion 0.07
Antisense oligonucleotides to polymorphisms expand targets and rescue patient-derived neurons in vitro 0.29
Individual and population-level risk factors for new HIV infections among adults in Eastern and Southern Africa 0.01
Meta-analysis of 22,710 human microbiome metagenomes defines an oral-to-gut microbial enrichment score and associations with host health and disease 0.06
MIDAS: rapid, multiplexed molecular profiling for integrated host–pathogen analysis 0.08
Minor SHIV variants abrogate protective efficacy of broadly neutralizing antibodies in rhesus macaques 0.93
Gut bacteria-derived sphingolipids alter innate immune responses to oral cholera vaccine antigens 0.14
Microbiome analysis of 940 lung cancers in never-smokers reveals lack of clinically relevant associations 0.05
The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC 0.03
A niche-dependent redox rheostat regulates epithelial stem cell fate 0.70
The Fanconi anemia pathway repairs colibactin-induced DNA interstrand cross-links 0.15
High expression of interleukin-18 receptor alpha correlates with severe respiratory viral disease and defines T cells with reduced cytotoxic signatures 0.07
Long COVID trajectories in the prospectively followed RECOVER-Adult US cohort 0.09
131 genetic loci highlight immunological pathways and tissues in nasal polyposis and asthma 0.03
Physical activity levels may impact on the risk of premature mortality in people with epilepsy 0.10
Scattering approach to diffusion quantifies axonal damage in brain injury 0.10
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database 0.27
Genome-wide CRISPR Screen Identifies Sec31A as a Key Regulator of Alpha Cell Survival 0.83
Molecular cartography of the human down syndrome and trisomic mouse brain 0.05
Social exposome and brain health outcomes of dementia across Latin America 0.03
Neural correlates of human fear conditioning and sources of variability in 2199 individuals 0.03
A decision-space model explains context-specific decision-making 0.04
Tonic dopamine and biases in value learning linked through a biologically inspired reinforcement learning model 0.92
Gastrointestinal neuroprosthesis for motility and metabolic neuromodulation 0.17
Exome analysis links kidney malformations to developmental disorders and reveals causal genes 0.02
Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations 0.10
Plasma proteomics for biomarker discovery in childhood tuberculosis 0.05
Genome sequencing is critical for forecasting outcomes following congenital cardiac surgery 0.27
Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge 0.00
Yanomami skin microbiome complexity challenges prevailing concepts of healthy skin 0.08
5 1.60
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling 0.02
Central role of glycosylation processes in human genetic susceptibility to SARS-CoV-2 infections with Omicron variants 0.07
Proteome-wide model for human disease genetics 0.68
Genome-wide association study and polygenic risk prediction of hypothyroidism 0.00
Single-cell and spatial transcriptomics of stricturing Crohn’s disease highlights a fibrosis-associated network 0.82
9 2.94
Autologous neutralizing antibodies and polyfunctional T cells contribute to long-term HIV-1 post-intervention control 0.13
Piezo1-dependent activation of stromal cells ignites muscle inflammation in exercise and injury and is associated with inflammaging 1.00
Identification of a potent V3 glycan site broadly neutralizing antibody targeting an N332 glycan-independent epitope 0.03
Rapid elicitation of neutralizing Asn332-glycan-independent antibodies to the V3-glycan epitope of HIV-1 Env in nonhuman primates 0.07
Spatial patterning of fibroblast TGFβ signaling underlies treatment resistance in rheumatoid arthritis 0.33
IgA-driven neutrophil activation underlies severe dengue disease after primary Zika virus infection in humans 0.12
Long COVID involves activation of proinflammatory and immune exhaustion pathways 1.00
Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapy 0.02
Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis 0.24
10 1.74
Population-scale genomic medicine with the Hong Kong Genome Project 0.01
Antisense oligonucleotide-mediated knockdown therapy in two infants with severe epileptic encephalopathy 0.72
Semaglutide on liver fibrosis and heart outcomes in patients at high risk of liver fibrosis: a prespecified analysis of the SELECT randomized trial 0.04
Deleterious coding variation associated with autism is shared across ancestries 0.08
Blood phosphorylated tau elevation as a biomarker in immunoglobulin light chain and transthyretin amyloidosis 0.06
Innate antiviral and immune functions associated with the HIV reservoir decay after anti-PD-1 therapy 0.04
Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study 0.01
Estimating the number of incorrect tuberculosis diagnoses in low- and middle-income countries 0.38
Clinical validation of an AI-based blood testing device for diagnosis and prognosis of acute infection and sepsis 0.03
Effects of vutrisiran on cardiac structure and function in patients with transthyretin amyloidosis with cardiomyopathy: secondary outcomes of the HELIOS-B trial 0.38
2 0.79
A disease-severity-responsive nanoparticle enables potent ghrelin messenger RNA therapy in osteoarthritis 0.54
Bioengineered photosynthetic nanothylakoids reshape the inflammatory microenvironment for rheumatoid arthritis therapy 0.25
4 1.82
Reduced mediodorsal thalamus activity underlies aberrant belief dynamics in a genetic mouse model of schizophrenia 0.06
Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics 0.09
Differential kinematic coding in sensorimotor striatum across behavioral domains reflects different contributions to movement 1.00
Addressing artifactual bias in large, automated MRI analyses of brain development 0.66
4 2.29
A multi-region recurrent circuit for evidence accumulation in rats 0.08
Tachykinin signaling defines distinct populations of glia in the enteric nervous system 0.62
Hunger modulates exploration through suppression of dopamine signaling in the tail of the striatum 0.88
Competitive integration of time and reward explains value-sensitive foraging decisions and frontal cortex ramping dynamics 0.72
3 0.49
Aging-related peroxisomal dysregulation disrupts intestinal stem cell differentiation through alterations of very long-chain fatty acid oxidation 0.10
Identification of five sleep-biopsychosocial profiles with specific neural signatures linking sleep variability with health, cognition, and lifestyle factors 0.01
Neural evidence that humans reuse strategies to solve new tasks 0.38
4 1.02
Trends in HIV self-testing uptake in Africa: A modeling study of population-based surveys and HIV testing program data 0.05
The benefits of investments to combat HIV, tuberculosis, and malaria for primary healthcare from 2000 to 2023: An economic modeling analysis 0.29
Urban and rural prevalence of tuberculosis in low- and middle-income countries: A systematic review and meta-analysis 0.67
Evaluating the biomedical and behavioral drivers of HIV incidence decline in adolescent girls and young women in Uganda: A mathematical modeling study 0.02
15 7.24
Migration-linked TB epidemics: How TB elimination in high-income countries depends on the success of TB control in high-burden settings 0.70
Antiretroviral therapy blocks natural selection on protective and disease-susceptible HLA-B alleles in HIV-1 infection 0.07
Bacteriophages target membrane-anchored glycopolymers to promote host cell lysis and progeny release 0.89
Structural insights into SetA-mediated Rab1 glucosylation and PI3P-guided localization during early Legionella infection 0.04
Probabilistic mapping and automated segmentation of human brainstem white matter bundles 0.56
Primate gut microbiota induce evolutionarily salient changes in mouse neurodevelopment 0.07
MAPK signaling and angiopoietin-2 contribute to endothelial permeability in capillary malformations 1.00
Scaffold vaccination for prevention of orthopedic device infection 0.75
Exceptionally broad HIV-1 neutralization via bispecific antibody–mediated prepositioning 0.43
Mapping macaque to human cortex with natural scene responses 1.00
Lysosomal reduced thiols are essential for mouse embryonic development 0.92
SHP2 genetic variants in NSML-associated RASopathies disrupt the PZR–IRX transcription factor signaling axis 0.05
Ensemble approaches for short-term dengue fever forecasts: A global evaluation study 0.11
Cell type–specific purifying selection of synonymous mitochondrial DNA variation 0.03
Predicting high-fitness viral protein variants with Bayesian active learning and biophysics 0.63
3 0.39
Body Composition in the General Population: Whole-body MRI-derived Reference Curves from Over 66 000 Individuals. 0.16
Standalone Endovascular Embolization versus Stereotactic Radiosurgery in the Treatment of Arteriovenous Malformations in Eloquent Brain. 0.16
Intratumoral Microbiome-related MRI Model for Predicting Breast Cancer Shrinkage Pattern Following Neoadjuvant Therapy. 0.08
9 2.60
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design 0.02
Population genomics of Anopheles darlingi, the principal South American malaria vector mosquito 0.25
Structural modeling reveals phage proteins that manipulate bacterial immune signaling 0.17
Implanted flexible electronics reveal principles of human islet cell electrical maturation 0.55
DNA origami vaccines program antigen-focused germinal centers 0.08
The specificity and structure of DNA cross-linking by the gut bacterial genotoxin colibactin 0.49
Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation 0.62
Reversible compromise of physiological resilience by accumulation of heteroplasmic mtDNA mutations 0.34
Machine learning–based penetrance of genetic variants 0.09
6 2.01
Preemptive cardioprotection with a small molecule in rodents that suppresses genes predictive of heart failure 0.06
Tunable TriPcides suppress virulence factor secretion during Staphylococcus aureus infection and kill dormant cells 0.08
RIN3 mutations impairing binding of the Alzheimer’s disease–associated protein BIN1 lead to RAB5 hyperactivation and endosomal pathology 0.90
Whole-brain meso-vein imaging in living humans using fast 7-T MRI 0.07
The designer cytokine IC7Fc attenuates atherosclerosis development by targeting hyperlipidemia in mice 0.01
Laser speckle particle sizer (SPARSE) informs the size distribution of tissue granularities 0.88
10 4.10
VRC01 with antiretroviral initiation in infants is well tolerated, and higher concentrations associate with greater HIV-1 DNA declines 0.09
Expansion of stemlike HIV-specific CD8+ T cells and limited viral epitope diversity characterize durable posttreatment control of HIV 0.59
Crystallized colony-stimulating factor-1 receptor inhibitor protects immunoisolated allo but not xeno transplants in primates 0.21
Immunopeptidomics can inform the design of mRNA vaccines for the delivery of Mycobacterium tuberculosis MHC class II antigens 0.10
Sex differences in HIV-1 reservoir cell selection are linked to altered innate immune profiles 0.54
Antigen-Fc fusion therapy reduces severity of a model of pemphigus vulgaris without systemic immunosuppression 0.90
Viral spike antigen clearance and augmented recovery in children with post-COVID multisystem inflammatory syndrome treated with larazotide 0.96
Vaccination with mRNA-encoded membrane-anchored HIV envelope trimers elicited tier 2 neutralizing antibodies in a phase 1 clinical trial 0.06
Adenovirus and mRNA vaccines as well as mucosal boosting improve protective efficacy against influenza virus challenge in macaques 0.62
Nonstabilized SARS-CoV-2 spike mRNA vaccination induces broadly neutralizing antibodies in nonhuman primates 0.02
1 0.03
Patterns of war related trauma in Gaza during armed conflict: survey study of international healthcare workers 0.03
4 2.05
A Novel Olfactory Cleft CT Staging System Reveals a Tri-Zone Anatomical Model and Biphasic Progression in Central Compartment Atopic Disease 0.14
CD25 expression marks an activated mast cell population in human nasal polyposis 0.98
Nasal microbiome and phageome profiles are associated with prospective respiratory viral infection risk in school-aged children 0.89
Epinephrine and Emergency Medical Services Activation Recommendations During Acute Allergic Reactions in Community Settings: International Consensus Report 0.04
4 1.01
Effect of baxdrostat on ambulatory blood pressure in patients with resistant hypertension (Bax24): a phase 3, randomised, double-blind, placebo-controlled trial 0.07
Deaths potentially averted by small changes in physical activity and sedentary time: an individual participant data meta-analysis of prospective cohort studies 0.05
Effectiveness of high-dose influenza vaccine against hospitalisations in older adults (FLUNITY-HD): an individual-level pooled analysis 0.07
Estimating the effect of maternal viral load on perinatal and postnatal HIV transmission: a systematic review and meta-analysis 0.82
3 0.96
Risk of recurrence after successful surgery for Cushing's disease and association with USP8 genotype and tumour size: an international, retrospective, longitudinal cohort study 0.08
3 months vs 12 months of romosozumab for postmenopausal osteoporosis (LIDA): an open-label, non-inferiority, randomised controlled trial 0.86
Association of gestational thyroid function and thyroid autoimmunity with gestational diabetes: a systematic review and individual participant meta-analysis 0.03
4 0.57
Evaluation of fluorometholone as adjunctive medical therapy for trachomatous trichiasis surgery (FLAME): a parallel, double-blind, randomised controlled field trial in the Jimma Zone, Ethiopia 0.04
Prevalence, awareness, treatment, and control of diabetes in India: a nationally representative survey of adults aged 45 years and older 0.09
Clinical impact and cost-effectiveness of the WHO-recommended advanced HIV disease package of care 0.37
Protection from killed whole-cell cholera vaccines: a systematic review and meta-analysis 0.07
2 0.11
Absolute and relative risks of mental disorders in families: a Danish register-based study 0.01
Long-acting oral weekly risperidone (LYN-005) for schizophrenia in the USA (STARLYNG-1): a multicentre, open-label, non-randomised phase 3 trial 0.10
12 1.52
Decompression with or without Duraplasty for Chiari I and Syringomyelia 0.02
Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock 0.02
Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism 0.11
Finerenone in Type 1 Diabetes and Chronic Kidney Disease 0.05
Cabotegravir plus Rilpivirine for Persons with HIV and Adherence Challenges 0.08
Mental Health Outcomes in Children after Parental Firearm Injury 0.95
Safety and Immunogenicity of an rVSV Lassa Fever Vaccine Candidate 0.02
Belzutifan for Advanced Pheochromocytoma or Paraganglioma 0.04
Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension 0.08
High-Dose Influenza Vaccine Effectiveness against Hospitalization in Older Adults 0.03
Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes 0.05
Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes 0.07

Numerical information only (in the tables above) is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International.