Clinical Sciences articles for Sichuan University (SCU), China

Time frame: 1 June 2025 - 30 May 2026

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Count: 101

Article ‘Count’ for Clinical Sciences.

Journal Count Share
6 4.55
An Acidosis-Activatable Nanocomposite for Synergistic Microenvironment Remodeling and Reprogramming of Innate–Adaptive Immune Crosstalk in Rheumatoid Arthritis 1.00
Neutrophil Granule-Mimetic Emulsion Inducing Gastrointestinal Immunity against Helicobacter pylori via Subcutaneous Vaccination 0.82
Dendritic Cell-Inspired Triple-Functional Biocatalysts with Atomic Iron Sites To Eradicate Drug-Resistant Bacteria and Biofilms 0.92
Oral Nanoarmored Live Bacterial Biotherapeutics Bearing Polyphenol-Based Supraparticles Enhance Chemotherapy via Reestablishing Immuno-Oncology-Microbiome Axis 0.72
Simultaneous Visualization of Anatomical Structure and Molecular Pathology Variation in Vascular Inflammation with Informationized Serum Albumin 0.10
Capillary Force-Driven Capture of Magnetic Nanoparticles in Calcium Phosphate Hollow-Tube Whisker Scaffolds for Osteonecrosis of the Femoral Head 1.00
1 0.78
Bioinspired and Absorbable Self-Gelling Powder with Anti-Polyelectrolyte Effect for Effective Hemostasis and Tissue Adhesion Prevention of Non-Compressible Wounds 0.78
9 6.19
Supramolecular Assembly of DNA Dendrimers and Antimicrobial Peptides for Synergistic Targeted Therapy of Infected Wounds 0.18
NIR‐Triggered Hydrogen‐Thermotherapy Regulates Inflammatory Circuits Between Macrophages and Synovial Fibroblasts in Rheumatoid Arthritis 1.00
Charge-Guided Deep Cartilage Targeting Carriers for Nav1.7-Mediated Osteoarthritis Treatment via Simultaneous Pain Management and Cartilage Protection 0.08
ROS‐Responsive Nanoplatforms for Atherosclerosis Photoacoustic Diagnosis and Endothelial Cell‐Macrophage Crosstalk Regulation 0.90
Engineered Nanosponge Platform Corrects TLR7-Related Efferocytosis and Platelet-Activation for Treatment of Different Systemic Lupus Erythematosus Stages 1.00
Phage-Inspired Nanomotor Synergized with Sono-Sensitive Antibiotics for Treating Multidrug-Resistant Klebsiella pneumoniae Lung Infection 0.29
Au-Modified SrTiO3 Nanoarray Featuring Enhanced Ultrasound-Responsive Mott–Schottky Heterojunction Speeds Bone Regeneration Through Sonodynamic Antibacterial and Inflammatory Management 1.00
Self‐Propelled Lung‐Targeting Nanovaccine Modulates Iron Homeostasis‐Immune Crosstalk for Therapeutic‐Prophylactic Intervention in Bacterial Pneumonia 1.00
Ferroelectric Heterojunction Membrane with Rapid Disinfection Through Coupling Piezoelectric and Pyroelectric Catalysis for Wound Regeneration 0.74
5 3.51
Lattice‐Reconstructed Ru‐Clusters on FeOOH‐Based Self‐Adaptive Artificial Peroxisome with Programmed ROS Regulation for Infectious and Inflammatory Chronic Wounds 0.90
LPS-Binding Hydrogel for TLR4-Mediated Microbiota-Immune Modulation 0.81
A Single-Cell-Inspired Self-Enrichment Therapeutic Strategy Delays Intervertebral Disc Degeneration by Inhibiting Pyroptosis 0.07
Janus Graphene Oxide Nanoplatform with Oppositely Functionalized Adhesion and Lubrication Enables Local Sustained Fenofibrate Release to Synergistically Halt Osteoarthritis 0.87
Push–Pull Electronic Effect and D‐Band Center Bi‐Modulated Bio‐Heterojunction Enzyme Enables All‐Stage Infected Wound Healing 0.86
2 0.97
Deletion of megalin in kidney tubular epithelium upregulates TGFβ1 signaling, aggravates ischemia/reperfusion kidney injury and accelerates the progression to CKD 0.06
Necroptosis Inhibition Preserves Diaphragm Function in Experimental Sepsis 0.92
1 0.01
A large-scale single-cell atlas reveals the pulmonary immune panorama in adult patients with influenza 0.01
2 0.39
Perspectives of children, parents and health care providers on outcomes following anesthesia for surgery:: An international mixed methods stakeholder engagement study from the Pediatric Perioperative Outcomes Group. 0.13
Bispectral Index-Guided Anesthesia for Older Patients Having Non-Cardiac Surgery: A Randomized Multicenter Trial. 0.27
3 1.08
Impact of Dexamethasone-Enriched Tumescent Anesthesia for Radiofrequency Ablation of GSV insufficiency: A Double-Blind Randomized Clinical Trial. 1.00
Long-Term Survival on Extent of Lymphadenectomy for Right-Sided Colon Cancer: Five-Year Follow-up Results of a Randomized Controlled Trial (RELARC Trial). 0.05
Defining Global Benchmarks for Robotic Liver Resections: An International Multicenter Study. 0.03
2 1.48
Tumor Necrosis Factor–Induced Neuropilin-2 in Fibroblast-Like Synoviocytes Exacerbates Rheumatoid Arthritis 0.82
Deficiency of cartilage‐specific Y‐box binding protein 1 represses NF‐κB signaling and alleviates osteoarthritis progression 0.67
1 0.05
Outcomes of endovascular aortic arch repair with an off-the-shelf modular inner branched stent-graft: an IDEAL 2a prospective multicentre trial 0.05
1 0.40
Selective targeting of endothelial and perivascular angiocrine ROCK2 treats liver fibrosis 0.40
2 1.02
Gut microbiota-derived indole-3-lactic acid suppresses anti-PD-1 efficacy in esophageal squamous cell carcinoma 0.98
Human monoclonal antibodies isolated after seasonal vaccination broadly neutralize antigenically drifted influenza B viruses 0.04
1 0.11
Regulating the photoelectric properties of porphyrin-based COF nanozymes by pillararene with polyphenol structure for efficient photo-enhanced antibacterial effect 0.11
1 0.44
Medical Thoracoscopy with versus without Prior Artificial Pneumothorax for Patients with Minimal or Absent Pleural Effusion 0.44
1 0.10
Impaired VLCFA-peroxisome-mediated intestinal epithelial repair causes gastrointestinal sequelae of long COVID 0.10
1 0.04
Effects of Extreme Heat Exposure on Heatstroke and Liver Injury in Mice: The Role of PPARα 0.04
1 0.03
Rice-derived recombinant human serum albumin as an alternative to human plasma for patients with decompensated liver cirrhosis: a randomised, double-blind, positive-controlled and non-inferiority trial 0.03
1 0.10
HBV induces liver fibrosis through the generation of reactive oxygen species in a pyruvate-dependent manner. 0.10
1 0.97
DNAH14 deficiency disrupts sperm annulus positioning and compromises offspring postnatal development 0.97
3 2.55
Exploring the interaction of obesity and allergy and the potential roles of gut microbiota in the development of this comorbidity in male mice 0.55
A U-shaped relationship between body mass index and the risk of elevated liver stiffness in older people: evidence from the 5‐year retrospective cohort study 1.00
Age-specific childhood obesity and adult cholelithiasis: association and shared transcriptomic bases 1.00
1 0.64
Digital Health Interventions in Pediatric Perioperative Care 0.64
1 0.50
Mapping ADHD Heterogeneity and Biotypes by Topological Deviations in Morphometric Similarity Networks 0.50
4 3.60
Significant Anxiolytic Effect and Enhanced Recovery Benefits of Perioperative Low-Dose Olanzapine in Patients with Anxiety Undergoing THA: A Randomized Controlled Trial. 1.00
Effect of Tourniquet Use on 3D Cement Penetration and Mid-Term Implant Stability in Primary Total Knee Arthroplasty: A Randomized Controlled Trial. 1.00
Efficacy and Safety of Tranexamic Acid Combined with Absorbable Hemostat in Reducing Perioperative Blood Loss in Total Knee Arthroplasty: A Prospective, Blinded, Randomized Controlled Trial. 1.00
A Deep Learning-Based Clinical Classification System for the Differential Diagnosis of Hip Prosthesis Failures Using Radiographs: A Multicenter Study. 0.60
1 0.08
Cognitive assessment in patients with primary aldosteronism vs patients with mild autonomous cortisol secretion 0.08
1 0.67
Epigenetically controlled endothelial promyelocytic leukemia drives liver inflammation and fibrosis 0.67
1 0.63
Fullerene for Reducing Acute Radiation Dermatitis in Patients Undergoing Radiotherapy for Head and Neck Cancer: A Phase II, Double-Blind, Randomized Controlled Trial. 0.63
1 0.01
Effect of Hypertension on Long-term Adverse Clinical Outcomes and Liver Fibrosis Progression in MASLD 0.01
1 0.17
Dissociable Neural Connectome Mapping of Reward and Punishment Responsiveness in Young Adults: Associations with Genetic Variability and Neurotransmitter Profiles 0.17
1 0.55
Caged-hypocrellin mediated antimicrobial photodynamic therapy as a dual-action strategy for fungal clearance and immune response regulation in drug-resistant Candida auris wound infections 0.55
1 0.90
Chirality-Driven Metal–Phenolic Artificial Enzymes Enable Renal Targeting and Antioxidative Therapy Enhancement for Acute Kidney Injury 0.90
6 3.09
Dynamic interactions between gut microbiome and host lipidome in antenatal depression: a large longitudinal study 0.53
Connectome-based growth models reveal individual heterogeneity and neurophysiological subtypes of subthreshold depression 0.04
Common alterations of whole and subregion-specific amygdala intrinsic functional connectivity across psychiatric disorders: a meta-analysis 0.77
NLRP3-mediated trained immunity of microglia is involved in the recurrence-like episode of depressive disorders 0.12
Disease clusters and their genetic determinants following a diagnosis of depression: analyses based on a novel three-dimensional disease network approach 0.63
Stress-induced reduction of sodium leak currents causes social deficits by impairing dorsal dentate gyrus-medial septum glutamatergic projection 1.00
2 1.33
Sugar-Responsive Enzyme–Polyphenol ‘Tooth Nanoarmor’ for Long-Lasting Caries Prevention via Glucose Depletion and Biofilm Suppression 1.00
A Metal–Phenolic Network-Coated Coacervate System Mediates Mitochondrial Modulation and Bone Homeostasis Restoration for Postmenopausal Osteoporosis Therapy 0.33
1 0.67
Psychedelics elicit their effects by 5-HT receptor-mediated G signalling 0.67
19 7.07
Btg2 inhibits Fmo1 UFMylation thus exacerbating ferroptosis and apoptosis in hepatic ischemia-reperfusion injury 0.07
RAISE: A computational tool for evaluating sarbecovirus spillover potential 0.12
A deep learning–based digital biopsy for predicting early recurrence in gastric cancer 0.11
Ultrasmall oral modulate gingival immunoactivation through type IV pili and TLR2-dependent endocytosis 0.04
Identification of altered immune landscape at single-cell resolution in NSCLC brain metastasis and its association with poor immune checkpoint inhibitor responses 0.07
Multi-ancestry GWAS of age-related hearing loss identifies 140 loci and key cellular mechanisms 1.00
Molecular mechanism of action of small molecule SMT-738 on bacterial lipoprotein transporter LolCDE 0.06
A comprehensive catalogue of receptor-binding domains in extracellular contractile injection systems 0.05
A bacterial defense system targeting modified cytosine of phage genomic DNA 0.93
High-entropy alloy Janus artificial enzymes for pH-gated sequential redox therapy of drug-resistant bacterial infection 0.83
Multi-omics analysis identifies a microbiota–bile acid–TLR signaling axis driving bladder injury in interstitial cystitis 0.94
Development of a replication-defective mpox virus platform for fundamental and therapeutic research 0.03
Mid-gestational cell-type-specific transcriptomic signatures in the prefrontal and superior temporal cortex in Down syndrome 0.12
Stable intracranial imaging of dura mater-engrafted pancreatic islet cells in awake mice 0.05
Physical activity levels may impact on the risk of premature mortality in people with epilepsy 0.78
Keratinocyte-specific H4K12 lactylation drives a non-canonical IL-17-dependent signaling in psoriasis progression in mice 0.13
NEXN protects against vascular calcification by promoting SERCA2 SUMOylation and stabilization 0.07
A longitudinal cohort study uncovers plasma protein biomarkers predating clinical onset and treatment response of rheumatoid arthritis 0.69
Protein kinase A is a dependent factor and therapeutic target in mouse models of fibrous dysplasia 1.00
1 0.01
Charting brain morphology in international healthy and neurological populations 0.01
1 0.73
Aging-related peroxisomal dysregulation disrupts intestinal stem cell differentiation through alterations of very long-chain fatty acid oxidation 0.73
3 1.61
Personalized functional topography–based multisite brain age prediction modeling reveals divergent neurodevelopment in major depression 0.06
Tubular ACSM3 deficiency impairs medium-chain fatty acid metabolism and aggravates kidney fibrosis 1.00
Pathophysiologically relevant bisphenol S exposure accelerates aging by disrupting brown adipose tissue–regulated energy metabolism 0.55
2 0.07
Impact of LI-RADS CT and MRI Ancillary Features on Diagnostic Performance: An Individual Participant Data Meta-Analysis. 0.05
Diagnostic Performance of CT/MRI LI-RADS Version 2018 Major Feature Combinations: Individual Participant Data Meta-Analysis. 0.02
4 2.85
Dynamic adaptive coassembled sericin protein orchestrating stem cell development for nucleus pulposus regeneration 0.80
Integrin inhibition facilitates fibrocartilaginous transformation in connective tissue in osteoarthritis 0.85
A self-assembled nano micelle-exosome with high selectivity and penetrability achieves precise intracartilage lipid delivery 1.00
Microenvironment-driven transformable self-assembly nanoplatform enables spatiotemporal remodeling for rheumatoid arthritis therapy 0.20
1 0.30
Medications for adults with type 2 diabetes: a living systematic review and network meta-analysis 0.30
2 0.95
Phage receptor specificity drives cross-resistance patterns and governs fitness trade-offs during sequential resistance acquisition in Salmonella 0.82
Global distribution of α/β hydrolase family macrolide esterases in Gram-positive bacteria 0.13
1 0.05
A Phase 3 Trial of Telitacicept for Systemic Lupus Erythematosus 0.05

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