Clinical Sciences articles for Zhejiang University (ZJU), China

Time frame: 1 June 2025 - 30 May 2026

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Count: 151

Article ‘Count’ for Clinical Sciences.

Journal Count Share
10 6.64
Self-Cascading Copper-Based Nanoassemblies Trigger Bacterial Cuproptosis-Like Death and Promote Wound Healing for Diabetic Drug-Resistant Bacterial Infections 1.00
A Bispecific Nanovehicle Disarms a Biofilm Amyloid Shield for Implant-Related Osteomyelitis Therapy 0.56
A Self-Alarming Nanoantidote for Early Urinary Diagnosis and Antioxidative Therapy of Drug-Induced Acute Kidney Injury 1.00
Mitochondria-Targeting Polymeric Micelles for Intervertebral Disc Degeneration Alleviation via Coordinated Cascade Energetic Intervention 1.00
In Situ Supply and Anchoring of Glycosaminoglycan by Dual-Modified Hydrogel Loaded with Glycoengineered Stem Cells for Attenuating Disc Degeneration 0.72
A Diselenide-Linkage Self-Assembled Nanoprodrug for Enhanced Osteoarthritis Treatment 0.09
On-Demand Collaborative Delivery for Remodeling the Senescent Microenvironment in Intervertebral Disc Degeneration 0.27
A Therapeutic System Regulating Iron Metabolism in CD63+ Macrophage Subsets Activates Anti-tumor Immunity for Bone Metastasis Therapy 0.74
An Activated Gasdermin Mimicking Polymer for Antitumor Immunity 0.94
Selenium Nanoplatform Engages Tranexamic Acid to Alleviate Ultraviolet B-Induced Skin Pigmentation via Inflammatory Response 0.33
6 3.78
Phagocyte-Inspired Supramolecular Self-Assembly Design of Abiotic Cell-Mimics for Pathogen Recognition and Eradication 0.77
An amyloid-based hydrogel with remineralizing and antibacterial properties for interrupting dental caries 0.09
Synergistic therapy with cerium-based nanozymes and mitochondrial RNA polymerase inhibition combats mitochondrial double-stranded RNA-mediated inflammation in osteoarthritis 0.89
Breast Implant microbiome profile correlates with foreign body response severity 0.03
Synergistic reversal of inflammation-mediated degeneration in intervertebral discs: Phenylboric acid-grafted hyaluronic acid hydrogel as an anti-oxidative vehicle for Timp-3 delivery and promotion of extracellular matrix synthesis 1.00
Collagen glycation-mediated mechanical stress aggravates ischemia-reperfusion injury 1.00
3 1.73
Near‑Infrared Driven Renal Nanomotors for Oxidative‑Stress Relief and Stone Prevention 0.50
Charge-Guided Deep Cartilage Targeting Carriers for Nav1.7-Mediated Osteoarthritis Treatment via Simultaneous Pain Management and Cartilage Protection 0.23
Rapid Self‐Gelling Powder Forms Dual‐Crosslinked Hydrogel for Robust Tissue Adhesion and Non‐Compressible Hemorrhage Control 1.00
2 1.35
Selective Induction of Cancer Cell Pyroptosis by Erbium Nanotuner Enhances Potent Anti‐Cancer Immunity 0.50
Mitochondria Rewiring by Polyphenol-Copper Nanodots to Truncate Mitochondrial-Endoplasmic Reticulum Crosstalk for Acute Kidney Injury Therapy 0.85
1 1.00
The effect of muscle quality index on the risk of adverse health outcomes: a prospective cohort study of 355,209 adults 1.00
1 0.05
The prognostic and clinical significance of cervical stromal invasion in endometrial cancer: a multicenter retrospective study 0.05
1 1.00
Cuproptosis Is Induced in Drug-Induced Liver Injury by Oxidative Stress–Mediated Copper Overload 1.00
2 0.50
Investigation of the Inoculum Effect of Antimicrobial Peptides Utilizing a Microfluidic Chip Platform 0.33
A Deep Multimodal Fusion Framework Integrating SERS, Clinical Data, and Metabolomics for Noninvasive MASH Diagnosis 0.17
1 0.03
Effect of Intravenous, Inhalational, or Combined Anesthesia Maintenance on Postoperative Respiratory Adverse Events in Children Undergoing Adenotonsillectomy (AmPRAEC): A Multicenter Randomized Clinical Trial. 0.03
1 0.02
Defining Global Benchmarks for Robotic Liver Resections: An International Multicenter Study. 0.02
4 0.17
Inhibition of the type I interferon receptor pathway protects against muscle weakness induced by dermatomyositis serum 0.03
Efficacy and safety of mufemilast in patients with Behçet’s syndrome: a phase 2 randomised clinical trial 0.06
Mycophenolate mofetil plus methotrexate versus cyclophosphamide with sequential azathioprine for treatment of Takayasu arteritis 0.05
Autoantibody reactome analysis reveals diagnostic biomarkers and molecular classification for relapsing polychondritis 0.03
5 1.43
Landscape of Somatic Mutations in a Large Cohort of Chinese Patients With Immune Dysregulations 0.26
A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome 0.04
OGFRL1 Deficiency Causes Chronic Recurrent Multifocal Osteomyelitis Via Pathologic Osteoclastogenesis, With Therapeutic Response to Tumor Necrosis Factor Inhibitor 0.60
Deficiency of AP1M2 causes a new autoinflammatory disease with colitis 0.50
Efficacy and Safety of Ivarmacitinib, a Selective JAK1 Inhibitor, in Patients With Active Ankylosing Spondylitis: Results From an Adaptive Seamless Phase 2/3 Trial 0.03
1 0.10
Outcomes of endovascular aortic arch repair with an off-the-shelf modular inner branched stent-graft: an IDEAL 2a prospective multicentre trial 0.10
1 0.19
Commensal enteric virome regulates intestinal carbohydrate digestion and absorption 0.19
3 1.48
Gut microbiota-derived deoxycholic acid shapes an immunosuppressive tumor microenvironment and promotes breast cancer progression 0.95
Plasma proteomic signature of frailty in 50,506 adults 0.42
Macrophage PD-1 regulates energy expenditure and metabolic dysfunction under immune checkpoint blockade 0.12
1 0.04
Effect of Continuous High-Frequency Oscillation Therapy on Lung Aeration in Mechanically Ventilated Patients with Impaired Consciousness: A Multicenter Randomized Controlled Trial 0.04
1 0.36
Targeting E3 Ubiquitin Ligase Hrd1 Prevents Myocardial Ischemia-Reperfusion Injury Through Enhancing ALDH2 Enzymatic Activity. 0.36
1 0.63
BAF60C links nucleolar stress to β cell dysfunction in type 2 diabetes through controlling Reg3b mRNA decay 0.63
1 0.08
Effects of Extreme Heat Exposure on Heatstroke and Liver Injury in Mice: The Role of PPARα 0.08
4 2.13
Enantioselective Transplacental Transfer of p-Phenylenediamine Quinones 1.00
Galacto-oligosaccharides ameliorate polystyrene nanoplastic-induced anxiety- and depression-like behaviors via a gut-initiated serotonergic cascade 0.20
Occurrence and Transplacental Transfer of Benzotriazole Ultraviolet Stabilizers in Maternal-Cord Serum and Association with Birth Outcomes 0.75
Elucidating the mechanisms of environmental pollutant BPA inducing neurotoxicity through metabolomics and network toxicology strategy 0.18
1 0.09
Association of urinary phthalate metabolite concentrations with inflammatory biomarker levels among pregnant women 0.09
3 0.77
Deglycosylation Enhances the Toxicity of Plant-Derived Glycosyl Bisphenol A during Gastrointestinal Digestion 0.06
Revealing Ferroptosis Induction by Bisphenol A and Bisphenol S through Distinct Protein Targets 0.67
Enhanced Phytopathogen Biofilm Control in the Soybean Phyllosphere by the Phoresy of Bacteriophages Hitchhiking on Biocontrol Bacteria 0.04
5 2.16
Two-step clinical care pathway to predict MASLD-related advanced fibrosis and long-term outcomes in type 2 diabetes 0.01
Single-cell analysis identifies RETNsup+/sup monocyte-derived Resistin as a therapeutic target in hepatitis B virus-related acute-on-chronic liver failure 0.91
Single-cell multimodal analysis reveals the dynamic immunopathogenesis of HBV-ACLF progression 0.74
Performance of the China-CLIF framework in acute-on-chronic liver failure: a multicohort study across all aetiologies 0.46
Rice-derived recombinant human serum albumin as an alternative to human plasma for patients with decompensated liver cirrhosis: a randomised, double-blind, positive-controlled and non-inferiority trial 0.03
4 0.99
Decoding tumor heterogeneity with imaging biomarkers predicts response to TACE plus Immunotherapy and targeted therapy in HCC. 0.06
Association between longitudinal weight change and clinical outcome in individuals with MASLD. 0.05
Chiglitazar in MASLD with hypertriglyceridemia and insulin resistance: A phase II, randomized, double-blind, placebo-controlled study. 0.03
Dissecting liver inflammation ecosystem identifies annexin A1 as a pro-resolving target for liver failure. 0.85
2 1.16
Gasdermin-D-mediated epithelial-immune circuit synchronizes nutrient absorption and host defense in the small intestine 1.00
Nociceptor-derived CGRP enhances dermal type I conventional dendritic cell function to drive autoreactive CD8+ T cell responses in vitiligo 0.16
1 0.05
Clozapine After 1 Failed Antipsychotic Drug Trial in First-Episode Psychosis 0.05
3 2.50
Aspartate treatment ameliorates metabolic dysfunction-associated fatty liver disease through upregulation of CBS and suppression of ferroptosis 1.00
Leber's hereditary optic neuropathy–associated ND1 3733G>C mutation ameliorates the mitochondrial quality control and cellular homeostasis 0.64
Mitochondrial tRNA processing defects reprogram mitochondrial and cellular homeostasis 0.86
1 0.20
A Deep Learning-Based Clinical Classification System for the Differential Diagnosis of Hip Prosthesis Failures Using Radiographs: A Multicenter Study. 0.20
4 1.28
BAF60a-dependent chromatin remodeling preserves β-cell function and contributes to the therapeutic benefits of GLP-1R agonists 0.39
Urine proteins reveal distinct coagulation and complement cascades underlying acute versus chronic lupus nephritis 0.06
A noncanonical parasubthalamic nucleus–to–extended amygdala circuit converts chronic social stress into anxiety 0.76
CXCL10 secreted by SPRY1-deficient epidermal keratinocytes fuels joint inflammation in psoriatic arthritis via CD14 signaling 0.06
1 0.01
Effect of Hypertension on Long-term Adverse Clinical Outcomes and Liver Fibrosis Progression in MASLD 0.01
1 0.25
Trametinib Treatment for Early-Stage Extracranial Arteriovenous Malformations: A Multicenter, Prospective, Single-Arm Pilot Study 0.25
1 0.67
Chemical Evolution of Natural Product for Discovery and Mechanistic Exploration of Antibiotic against MRSA 0.67
2 0.18
IVUS or Angiography Guidance for Percutaneous Coronary Intervention in Complex Coronary Bifurcation Lesions: The DKCRUSH VIII Randomized Clinical Trial 0.03
Long-Term Outcomes After Fractional Flow Reserve vs Intravascular Ultrasound to Guide PCI The FLAVOUR Trial Extended Follow-Up 0.15
2 0.83
Bmpr2 Drives Aberrant Activation and Injury of Glomerular Endothelial Cells in Lupus Nephritis. 0.79
Mycophenolate Mofetil versus Cyclophosphamide for Initial Therapy in Childhood-Onset Proliferative Lupus Nephritis: A Prospective, Multicenter, Randomized Trial. 0.05
1 0.81
An immunosuppressive tertiary lymphoid structure is associated with adverse prognosis in gastric-type endocervical adenocarcinoma 0.81
1 0.90
Angiopoietin-like 4 exacerbates renal tubular epithelial cell pyroptosis in acute kidney injury via integrin β5/FAK signaling pathway 0.90
1 0.86
Molecular mechanism of Eco8-mediated anti-phage defense 0.86
7 2.61
Local chemoarchitecture explains widespread lower cortical thickness associated with clinical high risk for psychosis 0.01
Peripheral immune–redox signatures associate with cortical network alterations in anhedonic depression 0.89
Connectome-based growth models reveal individual heterogeneity and neurophysiological subtypes of subthreshold depression 0.03
Gut microbiota modulates synaptic plasticity, connectivity, and dopamine transmission in the VTA-mPFC pathway in bipolar depression 0.80
Effects of esketamine on electrophysiology and metabolic reprogramming in brain organoids: insights into antidepressant mechanisms 0.45
Alterations in miR-151a-3p of plasma-derived exosomes and associated multimodal neuroimaging patterns in major depressive disorder 0.04
Characteristics of brain network connectome and connectome-based efficacy predictive model in bipolar depression 0.39
3 0.84
A metabolic alarmin from keratinocytes potentiates systemic humoral immunity 0.05
Psychedelics elicit their effects by 5-HT receptor-mediated G signalling 0.01
Loss-of-function mutations in PLD4 lead to systemic lupus erythematosus 0.78
1 1.00
Inducing bacterial calcification for systematic treatment and immunomodulation against methicillin-resistant Staphylococcus aureus 1.00
27 11.81
Machine learning model-guided selective use of temporary diverting ileostomy in rectal cancer surgery: a randomized controlled trial 0.50
Cryo-EM structures of ALECT2 filaments from human renal biopsies 0.50
Uromodulin p.His36Tyr promotes macrophage pyroptosis via App-Cd74 signaling to drive renal inflammation in ADTKD 0.05
ZFP36L2 is an interferon β -induced inhibitor that restricts the nuclear export of HIV-1 transcripts 0.01
Sequential sequencing reveals the architecture and complexity of genomic variants in patients with Alport syndrome 0.50
Prasugrel inhibits TLR7-driven autoimmunity in systemic lupus erythematosus by acetylating cGAS 0.05
Recycling senescent cell lipids for targeted senotherapy 1.00
Intrinsic capacity and stroke risk in a multiple cohort study 0.79
Proteomics-based machine learning model for predicting secondary infection in HBV-related liver failure 0.08
Targeting NAT10 alleviates colonic senescence and elderly-onset colitis by disrupting N4-acetylation of 0.98
A microbiota-IPA axis facilitates intestinal stem cell-mediated regeneration in colitis through a -associated program 0.71
Multi-modal AI for opportunistic screening, staging and progression risk stratification of steatotic liver disease 0.05
Discovery of antimicrobial peptides targeting via a pre-trained and fine-tuned few-shot learning-based pipeline 0.85
Endothelial IRE1α promotes thrombospondin-1 mRNA decay and supports metabolic stress adaptation of pancreatic islets 0.16
Co-occurrence of diverse defense systems shapes complex microbe-virus relationships in deep-sea cold seeps 0.09
Cryo-EM structure of renal AL amyloid fibrils from a patient with λ1 light chain amyloidosis 0.83
Exercise-induced histone lactylation in monocyte-derived macrophages restores cardiac immune homeostasis and function in sepsis-induced cardiomyopathy 0.75
Heat shock protein DNAJA2 controls insulin signaling and glucose homeostasis by preventing spontaneous insulin receptor endocytosis 0.20
DNA methylation patterns facilitate tracing the origin of neuroendocrine neoplasms 0.05
Single cell transcriptomics of human psoriasis and epidermal specific Ube2l3 deficient mice highlight CXCL16/CXCR6 involvement in psoriasis development 1.00
Structural basis for HIV-1 capsid adaption to a deficiency in IP6 packaging 0.04
A multifaceted strategy for intra- and extracellular nucleic acid regulation to alleviate intervertebral disc degeneration 0.09
Nascent liver proteome reveals enzymes and transcription regulators under physiological and alcohol exposure conditions 1.00
Microalgae-based Intestinal villi-targeting multistage biosystem for irritable bowel syndrome treatment 0.83
Physical and chemical niche of human growth plate for polarized bone development 0.65
Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge 0.00
A molecularly defined brain circuit module for regulating panic-like defensive state 0.05
1 0.91
Co-infusion of CD19-targeting and BCMA-targeting CAR-T cells for treatment-refractory systemic lupus erythematosus: a phase 1 trial 0.91
1 0.02
Charting brain morphology in international healthy and neurological populations 0.02
3 0.16
Converging dopamine pathways onto basolateral amygdala neurons encode exploration decisions 0.02
Sympathetic functional units encoded by genetically defined postganglionic neurons 0.08
An enteric-DRG pathway for interoception and visceral pain in mice 0.06
3 1.13
Reducing PTSD symptoms through unconscious intervention 0.13
Personalized functional topography–based multisite brain age prediction modeling reveals divergent neurodevelopment in major depression 0.03
Targeting of hyperlipid-producing senescent synovial fibroblasts to ameliorate cartilage degeneration 0.97
3 1.17
Contrast-Enhanced US Using Perfluorobutane for Diagnosing Small HCC in High-Risk Patients: Comparison with MRI LI-RADS Version 2018. 0.14
Spatiotemporal Development and Clinical Correlates of MRI-based Brain Myelination in Term- and Preterm-born Children. 0.97
Comparison of a Specialized Large Language Model with GPT-4o for CT and MRI Radiology Report Summarization. 0.05
1 0.03
An Aeromonas variant that produces aerolysin promotes susceptibility to ulcerative colitis 0.03
3 2.43
Reduced MGE burden, virulence optimization, and acid stress tolerance shape the clonal succession of MRSA ST59 0.76
Bacteriocin-transport–inspired oral peptide-probiotic delivery ameliorates IBD complications via autophagy and gut homeostasis 0.72
Bacteriophage immunotherapy with artificial antigen-directed immune labeling against bacterial infection 0.95
3 1.07
Epigenetically regulated pancreatic GABA-somatostatin signaling underlies gestational diabetes–induced glucose intolerance in offspring 0.39
A randomized, double-blind, placebo-controlled phase 1 trial of the topical pan–lysyl oxidase inhibitor PXS-6302 in mature scars 0.03
A cationic polymer drives glycosaminoglycan assembly and secretion for preclinical osteoarthritis therapy 0.65
5 1.19
Reliability of urological telesurgery compared with local surgery: multicentre randomised controlled trial 0.21
Preimplantation genetic testing for aneuploidy versus no genetic testing in couples undergoing intracytoplasmic sperm injection for severe male infertility: multicentre, open label, randomised controlled trial 0.15
Comparative efficacy and safety of exercise modalities in knee osteoarthritis: systematic review and network meta-analysis 0.38
Efficacy and safety of anrikefon in patients with pruritus undergoing haemodialysis: multicentre, double blind, randomised placebo controlled phase 3 trial 0.09
Effect of lateral versus supine positioning on hypoxaemia in sedated adults: multicentre randomised controlled trial 0.36
1 0.02
Sulfoquinovose degradation by cow rumen microbiota 0.02
2 0.17
Deep learning and statistical methods identify novel asthma risk variants in Europeans 0.08
Aberrant ceramide accumulation fuels eosinophilic inflammation by promoting EET formation and release in CRSwNP 0.08
1 0.03
Global variation in patient factors, interventions, and postoperative outcomes for those undergoing trauma laparotomy: an international, prospective, observational cohort study 0.03
1 0.07
Sentinel-Lymph-Node Biopsy Alone or with Lymphadenectomy in Cervical Cancer 0.07
1 0.11
Metatranscriptomics Reveals System-Specific Viral Adaptive Strategies and Prokaryotic Defense Trade-offs Across Anaerobic Digestion Systems 0.11

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