Genetics articles for Canada

Time frame: 1 May 2025 - 30 April 2026

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Count: 65

Article ‘Count’ for Genetics.

Journal Count Share
3 0.96
Heterozygous pathogenic variants in the splicing factor SF1 lead to a large spectrum of neurodevelopmental disorders 0.02
Rare variants in PRKCI cause Van der Woude syndrome and other features of peridermopathy 0.03
Molecular and developmental deficits in Smith-Magenis syndrome human stem cell-derived cortical neural models 0.91
1 0.09
Diverse Genetic Etiologies of Unilateral Polymicrogyria 0.09
1 0.04
Transposable elements as novel therapeutic targets for PARPi-induced synthetic lethality in PcG mutated blood cancer 0.04
2 0.31
TSC2 loss in neural progenitor cells suppresses mRNA translation of neurodevelopmental genes 0.18
Loss of DOT1L disrupts neuronal transcription and leads to a neurodevelopmental disorder 0.13
1 0.05
Deletion of METTL14, a key methylation regulator, attenuates vascular ageing 0.05
1 0.85
Multi-species analysis of inflammatory response elements reveals ancient and lineage-specific contributions of transposable elements to NF-kB binding 0.85
1 0.11
The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway 0.11
6 5.20
A tryptophan-phenylalanine binding motif for the histone methyltransferases MLL4 and MLL3 0.20
A disease-causing Isoleucyl-tRNA synthetase variant leads to altered protein complex formation and cellular stress response 1.00
BMI1 represses G-quadruplex DNA formation to maintain genomic stability during replication 1.00
Distal tip cell migration mutants of Caenorhabditis elegans are rescued by bioequivalent outputs from chondroitin and N-glycosylation pathways 1.00
SET7/9 exhibits sigmoidal kinetics on nucleosomes, hyperbolic kinetics on histones by an ordered sequential mechanism, and methylates lysine and arginine 1.00
Molecular determinants of nucleic acid recognition by an RNA-targeting ADP-ribosyltransferase toxin 1.00
2 1.13
Actomyosin cortex integration with complex plasma membrane topography in the early Drosophila embryo 1.00
Arc controls organ architecture through modulation of Crb and MyoII 0.13
2 0.20
Functional consequence of pathogenic GABRA3 variants determines whether X-linked inheritance is dominant or recessive 0.08
EZH2 crosstalk with RNA methylation promotes prostate cancer progression through modulation of m6A autoregulation pathway 0.12
1 0.50
Higher Promoter Methylation of the Ubiquitin-Associated and SH3 Domain Containing A (UBASH3A) Gene Is Associated With T-Lymphocyte Ontogeny and Reduced Susceptibility to Early-Onset Sepsis 0.50
1 0.08
Human mitochondrial RNA polymerase structures reveal transcription start site and slippage mechanism 0.08
5 1.54
Genome-wide tandem repeat expansions modify schizophrenia risk in the presence of a 22q11.2 deletion 0.16
Elevated brain glutamine levels in adults with autism spectrum disorder: A 7T MRS study 0.20
Investigating milk-derived extracellular vesicles as mediators of maternal stress and environmental intervention 0.27
Longitudinal multi-omics analysis of umbilical cord blood and childhood serum in Autism 0.06
Transcriptomic and epigenomic consequences of heterozygous loss-of-function mutations in , a shared risk gene for bipolar disorder and schizophrenia 0.85
2 0.24
CFAP20 salvages arrested RNAPII from the path of co-directional replisomes 0.07
NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers 0.17
12 6.59
The effect of the fitness gradient on fixation probability 0.20
Astrocyte fatty acid metabolism as a driver of risk for major depressive disorder 0.77
A dual role of EZH2 in regulating A-to-I RNA editing and mRNA stability through ADAR 0.07
Blood-based epigenetic instability linked to human aging and disease 0.90
Viral mimicry acts as a tumor suppressor in colitis 0.89
H3K36 Methylation as a Guardian of Epigenome Integrity 1.00
Epigenome-wide association study of nuclear DNA methylation in relation to mitochondrial heteroplasmy 0.02
A nuclear TRiC/CCT chaperonin assembles meiotic HORMAD proteins into chromosome axes competent for crossing over 0.67
Concurrent temporal patterning of neural stem cells in the fly visual system 1.00
REST/NRSF Preserves muscle stem cell identity by repressing alternate cell fate 0.79
Somites are a source of nephron progenitors in zebrafish 0.22
A highly conserved neuronal microexon in DAAM1 controls actin dynamics, RHOA/ROCK signaling, and memory formation 0.06
3 0.89
Pathogenic variants cause a neurodevelopmental syndrome by impairing synaptic function 0.05
Bryophytes hold a larger gene family space than vascular plants 0.02
Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression 0.82
1 0.17
Spatial, temporal and Notch determination of terminal selector expression controls neuronal cell fate in the optic lobe 0.17
1 0.69
Protective ApoE variants support neuronal function by effluxing oxidized phospholipids 0.69
3 2.22
Biased sampling driven by bacterial population structure confounds machine learning prediction of antimicrobial resistance 0.22
AMPK modulates a DEAH box RNA-helicase to attenuate TOR signaling and establish developmental quiescence in Caenorhabditis elegans 1.00
Microglial deficiency in the ATRX chromatin remodeler elicits a viral mimicry immune response that impacts neuronal function and behavior. 1.00
1 0.29
Early life starvation and Hedgehog-related signaling activate innate immunity downstream of daf-18/PTEN and lin-35/Rb causing developmental pathology in adult C. elegans 0.29
1 0.13
Joint Distribution of Nuclear and Cytoplasmic mRNA Levels in Stochastic Models of Gene Expression: Analytical Results and Parameter Inference 0.13
6 2.98
Cnpy1 is a candidate endoplasmic reticulum chaperone of vomeronasal type 2 GPCRs 0.17
The Nemp1–Nesprin complex mediates cellular responses to matrix mechanics 0.21
Generative epigenetic landscapes map the topology and topography of cell fates 1.00
ITAF45 is a pervasive trans-acting factor for picornavirus Type II IRES elements 0.45
Transgenerational epigenetic effect of kings’ aging on offspring’s caste fate mediated by sperm DNA methylation in termites 0.14
CDADC1 is a vertebrate-specific dCTP deaminase that metabolizes gemcitabine and decitabine to prevent cellular toxicity 1.00
2 1.75
Metabolic consequences of naturally occurring mitochondrial heteroplasmy in bivalves 0.75
Haplodiploidy accelerates mitogenome evolution in insects 1.00
5 2.56
Morphogenesis of moss leaf-like organs through variations in deeply shared developmental principles 0.55
Multimodal social context modulates larval behavior in Drosophila 0.11
Widespread association of Polycomb complex–deposited histone H2A monoubiquitylation with enhancers and neuronal gene regulation 1.00
A phylogenetic approach uncovers cryptic endogenous retrovirus subfamilies in the primate lineage 0.29
Dual DNA demethylation mechanisms implement epigenetic memory driven by the pioneer factor PAX7 0.62
1 0.33
Germ granule localization of nematode Argonaute WAGO-4 ensures fidelity in small RNA loading. 0.33

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