Immunology articles for China

Time frame: 1 May 2025 - 30 April 2026

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Count: 466

Article ‘Count’ for Immunology.

Journal Count Share
16 14.78
Single-Cell Sequencing Analysis-Driven Nanomedicine Design for Mimicking Endogenous Immune Repair in Myocardial Infarction 1.00
Adrenomedullin Antagonist Nanoparticles Inhibit Breast Cancer Brain Metastasis by Immunomodulating Monocytes/Macrophages 0.91
Charge-Adaptive Nanoparticle Attenuates Inflammation via Targeting Neutrophil Extracellular Traps (NETs) and Breaking NETs–Macrophage Crosstalk 1.00
Leveraging Naturally Assembled Tumor Extracellular Vesicles as Self-Adjuvanting Nanovaccines to Potentiate Cancer Immunotherapy via cGAS/STING Activation 1.00
Promoting Endogenous Danger Signals Accumulation by a Hierarchical Nanoinducer for Amplifying STING Pathway Activation-Mediated Tumor Immunotherapy 1.00
Programmed Cell Death Protein 1 Engagement Impairs Cytoskeletal Forces and Nuclear Mechanotransduction in T Cells 1.00
Proinflammatory Macrophage-Targeted Nanoparticles Rejuvenate Aged Macrophages and Their Phagocytic Capacity 0.20
mRNA-Based Vaccination Drives in Vivo Dendritic Cell Reprogramming and Selective Cytotoxic T Lymphocyte Modulation for Enhanced Antitumor Immunity 0.67
Pulmonary Surfactant Protein-Hitchhiking Inhalable Vaccines Augment Mucosal and Systemic Antiviral Immunity 1.00
Magnetic-Responsive Semilifeform for Protecting Peritumoral T Lymphocytes and Precise Tumor Eradication 1.00
Picroside II-Encapsulated Nanoformulations as Pyroptosis Inhibitor Alleviate Cytokine Storms and Remodel Gut Microbiota Disturbances 1.00
An Antigen-Free Nanovaccine-Enabled Holo-Immunotherapy for Establishing Robust Memory Immune Tolerance in Autoimmune Diseases 1.00
Reprogramming Macrophage Function via Cholesterol Modulation and Redox Signaling Using a Multifunctional Nanoplatform for Postoperative Breast Cancer Management 1.00
Reprogramming Macrophage via an Antigen Phagocytosis-Presentation Nanoenhancer for Improved Cancer Immunotherapy 1.00
Focused Acoustic Vortex-Activated Dual-Stimuli Nanoplatform Synergizes with Checkpoint Blockade to Enhance Macrophage Phagocytosis and Antitumor Immunity 1.00
Artificial Tolerogenic Dendritic Cell-Derived Vesicles Prepared by High-Pressure Homogenization for Potent Immunotherapy of Type 1 Diabetes 1.00
6 5.83
Hydrogels with hierarchical hydrogen bonds enable tunable stress relaxation to direct macrophage-driven immunoregulation 1.00
Nanobody-based high-performance multitarget immunosorbents protect against sepsis by concurrently adsorbing endotoxins and inflammatory cytokines 1.00
Mitochondria-targeted manganese-based mesoporous silica nanoplatforms trigger cGAS-STING activation and sensitize anti PD-L1 therapy in triple-negative breast cancer 1.00
IL-21R-Targeted Nano-immunosuppressant Prevents Acute Rejection in Allogeneic Transplantation by Blocking Maturation of T Follicular Helper Cells 1.00
Engineered probiotics remodel the intestinal epithelial barrier and enhance bacteriotherapy for inflammatory bowel diseases 1.00
Immuno-engineered macrophage membrane-coated nanodrug to restore immune balance for rheumatoid arthritis treatment 0.83
7 6.83
A “Depolarization‐Activation” Strategy Targeting Microglia: Cuproptosis‐Mediated Immune Re‐Sensitization Nanoplatform in Glioma Therapy 1.00
Sonodynamic/Mechano‐Induced cGAMP Biosynthesis Enables In Situ STING Activation for Enhanced Cancer Immunotherapy 0.93
Targeting Microglia Extracellular Traps via an “Internal‐External” Synergistic Strategy to Reshape the Dysregulated Microglia‐Neuron Axis for Spinal Cord Injury Recovery 1.00
Multi‐Target Nanoscavengers for Interrupting the Feed‐Forward Inflammatory Cycle in Autoimmune Diseases 1.00
Genetically Programmable Biohybrid Nanoplatform Enables Cuproptosis-Immunotherapy via Spatiotemporal Control of Macrophage Polarization and Copper Flux 1.00
Inhibiting Senescence‐Associated Macrophage‐Epithelia Cell Communication via siPLAU Gene‐Patch for Colorectal Cancer Treatment 1.00
Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy 0.90
9 8.31
In Situ Peptide Self-Assembly Augments Antibody Recruitment for Tumor Immunotherapy 1.00
Reengineering Aligned D‐Orbital Energy Levels in FeMn Dual‐Atom Nanozyme Inhibits Pyroptosis for Effective Alleviation of Inflammatory Diseases 1.00
Unique Dual‐Affinity Strategy for Specific Lipopolysaccharide Clearance in Sepsis Therapy: Peptide‐Conjugated Molecularly Imprinted Polymers via Emulsion Interfacial Polymerization 1.00
Ultrasound‐Activated Piezoelectric Nanoparticles Targeting and Activating NK Cells for Tumor Immunotherapy 1.00
Fueling IgA-Dominated Humoral Immunity with an Intranasal Hybrid Tumor Vaccine to Opsonize and Strike Epithelial Breast Cancer 1.00
Liver‐Targeted Tolerogenic Vaccines: A Nano‐Membrane Coupled Approach for Autoimmune Disease Therapies 1.00
Intranasal and Intravenous Sequential Administration of Survivin Peptide‐CpG Nanovaccines Elicits Potent Immunity Toward Glioblastoma 1.00
A Single-Cell Atlas-Inspired Hitchhiking Therapeutic Strategy for Acute Pancreatitis by Restricting ROS in Neutrophils 1.00
Differential Optical Imaging of Antigen Presentation Machinery Using Molecular Optical Reporters 0.31
2 2.00
KLF Transcription Factor 5/Lysophosphatidic Acid Receptor 5 Induced M2 Macrophage Activation and Inflammation by Modulating Phosphorylation of Mitogen-Activated Protein Kinase Kinase Kinase 7 in Pediatric Asthma 1.00
Notch signaling aggravates Helicobacter pylori-induced inflammation by promoting macrophage activation and pro-inflammatory Th1/Th17 responses 1.00
1 0.55
Rademikibart Treatment for Moderate-to-Severe Uncontrolled Asthma: A Phase 2B Randomized Clinical Trial 0.55
5 5.00
Label-Free Raman Spectral Identification of NK and NKT Cells in Immune Heterogeneous Cell Populations 1.00
Aptamers Generated by Multi-Strategy Selection Target FcγRI and Block IgG Fc-FcγRI Interaction 1.00
A Versatile Tool for Imaging Neutrophil Elastase in Diabetic Complication 1.00
IL-2 and IFN-γ Secretion of Activated Jurkat T Cells via a Microdroplet-SERS based Single-Cell Immunoassay (Drop-SCIA) 1.00
Evaluation of Antiviral Activity of Lactoferrin in Bovine Milk Toward Fondaparinux Using Ordered Porous Layer Interferometry 1.00
4 4.00
4-Dimethylaminophenol: A ‘Smaller’-Molecule PPI Inhibitor Targeting the PSD95 GK Domain Against Ischemic Stroke 1.00
Engineered Biomimetic Nanoparticles With Targeted Delivery of Chlorothiazide for the Treatment of Inflammatory Bowel Disease 1.00
Persistent Membrane‐Anchored Oligomeric Peptides with Nanopore Formation for Targeted Immune Modulation 1.00
Restoring Cell–Cell Communication to Elicit Bystander Effect Using a DNA‐Based Nanocomplex for Robust Immunotherapy 1.00
4 2.87
A human-STING specific macrocyclic peptide suppresses cGAS-STING-induced inflammation 1.00
Clinical and biologic predictors of thrombosis in persistently antiphospholipid antibody-positive patients: Prospective analysis of the International APS ACTION Clinical Database and Repository (‘Registry’) 0.05
IL-2 signalling sustains pathogenic age-associated B cell homeostasis in lupus 0.85
Genetically modified CD19-targeting IL-15 secreting NK cells for the treatment of systemic lupus erythematosus 0.97
3 1.98
<atl>Single‐cell scpRNA/scp sequencing informs precision targeting of monogenic lupus associated with scp iIKZF1/i /scp haploinsufficiency</atl> 1.00
MDSC-derived IFN-β promotes T follicular helper cell response and exacerbates lupus development 0.94
Diagnostic implications and correlates of plasma ADA2 activity and ADA2 variants 0.04
5 3.16
CDK8/CDK19 inhibition restores T-cell homeostasis in primary immune thrombocytopenia 1.00
The neutrophil antigen 3a/b polymorphism in SLC44A2 unexpectedly encodes the Csa/Csb red cell antigens 0.10
A first-in-class JAK/ROCK inhibitor, rovadicitinib, for glucocorticoid-refractory or -dependent chronic GVHD 1.00
Safety and efficacy of rilzabrutinib vs placebo in adults with immune thrombocytopenia: the phase 3 LUNA3 study 0.06
Platelet NLRP6 protects from microvascular thrombosis in sepsis 1.00
1 0.03
Altered T-cell reactivity in the early stages of Alzheimer's disease 0.03
3 1.98
B cells disrupt tertiary lymphoid structure formation and suppress anti-tumor immunity 1.00
DNASE1L3-expressing dendritic cells promote CD8+ T cell function and anti-PD-(L)1 therapy efficacy by degrading neutrophil extracellular traps 0.91
A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis 0.07
10 8.51
LINE-1 Retrotransposon Protein ORF1p Forms Condensates That Drive cGAS-Induced Immune Evasion in Lung Squamous Cell Carcinoma 0.85
Artificial Intelligence and Multimodality Data Integration Decipher Tertiary Lymphoid Structure Maturity in Gastric Cancer. 0.88
circADAMTS12 Inhibits the Antitumor Activity of Microglia to Enable Metastatic Colonization in the Brain 0.92
Surgery-Induced Neutrophil Extracellular Traps Promote Tumor Metastasis by Reprogramming Cancer Cell Lipid Metabolism 0.09
ChREBP-Mediated Choline Deprivation and Chemokine Secretion Shape Tumor-Associated Macrophages to Promote Immune Evasion 0.92
Pro-tumor Macrophage Polarization Mediated by BMP2/4-ACVR1 Signaling Orchestrates an Immunosuppressive Microenvironment During Tumor Initiation. 1.00
SPP1+ Neutrophils Mediate Resistance to Immune Checkpoint Blockade in BAP1-Inactivated Tumors 1.00
USP20-Driven Cholesterol Metabolism Links Inflammatory Signaling to Malignancy and Stromal Co-evolution in Pancreatic Cancer. 0.95
ZNF296 Drives Immune Evasion in Epithelial Cancers by Repressing Immune Stimulatory Genes. 0.90
SLC3A2-Mediated Lysine Uptake by Cancer Cells Restricts T-cell Activity in Hepatocellular Carcinoma 1.00
3 2.39
Sympathetic-epithelial crosstalk governs tissue-resident memory T cell immunosurveillance in the skin 1.00
SARM1 senses dsDNA to promote NAD+ degradation and cell death 1.00
Proximity between LAG-3 and the T cell receptor guides suppression of T cell activation and autoimmunity 0.39
5 2.93
Gut DNA virome enterotype dictates inflammation heterogeneity through tuning the phage-bacteria-sphingosine-intestine axis in Crohn's disease 0.86
HMGB1 functions as a critical mediator of host defense at the gut mucosal barrier 0.05
Microbiota utilization of intestinal amino acids modulates cancer progression and anticancer immunity 0.08
A CLOCK-targeting lncRNA induces trained immunity against tuberculosis 1.00
Veillonella intestinal colonization promotes C. difficile infection in Crohn’s disease 0.94
1 1.00
Catenibacterium mitsuokai promotes hepatocellular carcinogenesis by binding to hepatocytes and generating quinolinic acid 1.00
1 1.00
In vivo CAR-Tfh cell reprogramming restores tolerance in a mouse model of autoimmune hepatitis 1.00
1 1.00
A dual-site fluorescent probe for tracing the interaction between ATP and NE in neuroinflammation 1.00
2 2.00
In situ released bacterial membrane vesicles activate the STING pathway via boosting the intracellular DNA pool for immunotherapy 1.00
TRAP: a contrastive learning-enhanced framework for robust TCR–pMHC binding prediction with improved generalizability 1.00
2 1.92
Macrophage PRMT9 Ameliorates Acute Myocardial Infarction by Promoting Symmetric Dimethylation and Degradation of STAT1. 1.00
Mitochondrial 1-Carbon Metabolism Drives CD34-Lineage Cells to Differentiate Into T Follicular Helper Cells to Form Tertiary Lymphoid Organs in Transplant Arteriosclerosis. 0.92
2 2.00
Interleukin-6-Associated Pyroptosis, Apoptosis, and Necroptosis via JAKs/STAT3-RIPK1 Axis: A Potential Mechanism for CD4+ T-Cell Depletion in Bacterial Sepsis. 1.00
Early T-Lymphocyte Depletion Predicts Mortality in Critically Ill Children With Severe Infections: An Exploratory Analysis of Cytokine Pathways. 1.00
3 3.00
MITA/STING-driven CD38 induction in Siglec-Flow macrophages promotes regulatory T cell survival and non-small cell lung cancer progression 1.00
Inchworm migration facilitates amoeboid cell adaptation to high-adhesion environments 1.00
Targeting VSIG4+ tissue-resident macrophages enhances T cell cytotoxicity and immunotherapy efficacy in cancer 1.00
2 2.00
Evaluating the Effects of Neburon Exposure on Ovarian Folliculogenesis Using Zebrafish and Mouse Granulosa Cell Line 1.00
Evaluating the Effects of Neburon Exposure on Ovarian Folliculogenesis Using Zebrafish and Mouse Granulosa Cell Line. 1.00
11 10.94
Mechanism of neuroinflammation and cardiovascular toxicity induced by tributyltin: Evidence from zebrafish (Danio rerio) models and network toxicology studies 1.00
Multi-omics Analysis and Preliminary Experimental Validation of Acetyl Tributyl Citrate (ATBC) Promoting Bladder Cancer Progression via the AKR1B1/EMT Axis 1.00
ERα-mediated endoplasmic reticulum stress drives 4-tert-octylphenol–induced cardiac developmental toxicity in zebrafish 1.00
Trichloroethylene induces cardiomyocyte senescence through an AhR–ROS–IL-1 axis and amplified by Wnt/β-catenin suppression 1.00
EBV-driven rewiring of Drp1-Mediated mitophagy exacerbates trichloroethylene-induced hypersensitivity syndrome 1.00
Short-chain fatty acids alleviated fluoride-induced neuroinflammation via the gut-brain axis in rats 0.94
AhR/PPARγ mediates hepatic lipid metabolism disorders induced by exposure to 16 priority-controlled PAHs at environment related doses 1.00
Investigating the mechanisms of Triclocarban-induced liver injury: A comprehensive analysisbased on network toxicology and in vivo experiments 1.00
Genome-wide alterations of DNA methylation and hydroxymethylation in uroepithelial cells revealed potential carcinogenicity of halobenzoquinone disinfection byproducts 1.00
Steroid hormones and their combinations affect circadian rhythm pathway in F0 Gambusia affinis using transcriptome sequencing: validation by life-long exposure of F1 offspring and molecular dynamics 1.00
Screening and prediction of potential androgen receptor agonists in indoor dust 1.00
6 6.00
Contribution of AhR-mediated activation of the AC/cAMP/PKA cascade to 6PPDQ-induced cardiac defects in zebrafish 1.00
Redox Imbalance and NF-κB Activation Drives 1,3-diphenylguanidine (DPG)-Induced Hepatotoxicity in Grass Carp (Ctenopharyngodon idella): HSP70 as a Protective Therapeutic Target 1.00
Isothiazolinone biocides as aromatase inhibitors: Hormonal disruption, and in silico docking and SAR/QSAR analysis 1.00
Metabolism exploration of disinfection byproducts halonitromethanes (HNMs) by cytochrome P450 enzymes and toxicity evaluation 1.00
1,2-bis(2,4,6-tribromophenoxy) ethane, a novel brominated flame retardant, induces hepatic fibrosis: New insights into crosstalk between macrophage extracellular traps and stellate cell activation 1.00
17β-Trenbolone increases circulating myeloid-derived MMP8 in CSDS-induced mice and drives depressive tendencies to social threat 1.00
12 11.02
Mechanistic Insights into the Cardiotoxic Effects of Dextromethorphan and Its Metabolite Dextrorphan in Zebrafish Using Network Toxicology and Molecular Dynamics 1.00
Transgenerational Hazards Evade Traditional Safety Thresholds: ryr1b Hypermethylation Mediates Azoxystrobin-Induced Transgenerational Developmental Toxicity in Zebrafish (Danio rerio) at Subthreshold Exposure 1.00
Conformation of CD40LG and ANXA5 as Key Events of 2,7-Dibromocarbazole-Induced Cardiotoxicity Using in Vivo and in Vitro Models 0.78
Azocyclotin Binds CDK4 to Disrupt DNA Methylation in Zebrafish Epigenetic Transgenerational Inheritance 1.00
Aryl Hydrocarbon Receptor Activation Mediates Acute Lethality and Developmental Toxicity of Polychlorinated Diphenyl Ethers in Vertebrates: Mechanistic Insights and Implications for Toxicity Equivalency Factor Frameworks 0.92
PPARα Activation-Mediated Testosterone Reduction as the Key Adverse Outcome Pathway for Cd-Induced Male Infertility: A Novel Integrated Approach 1.00
Discovery of the Insecticide Chlorantraniliprole as a Thyroid Hormone Receptor β Antagonist Reinforcing Thyroid-Liver Metabolic Disruption to Promote Metabolic Dysfunction-Associated Steatotic Liver Disease 1.00
Indoor Dust Increases the Risk of Iron-Loading Anemia in Mice through Exogenous Iron-Induced Ineffective Erythropoiesis 1.00
Genetic Polymorphisms in Nuclear Receptors Drive Variations in Responses to Environmental Exposures 0.67
Beyond Competitive Binding: New Biochemical Insights Challenge Endocrine Disrupting Chemical Screening Paradigms 0.90
Cellular Response to Halobenzoquinone Disinfection Byproducts Mediated by Aryl Hydrocarbon Receptor: Integrated Metabolomic and Transcriptomic Analysis 1.00
Development and Cross-Validation of a Zebrafish Quantitative Adverse Outcome Pathway Model on Aromatase Inhibition Leading to Reproductive Dysfunction 0.75
1 1.00
Targeting P2Y14R alleviates platelet-induced NET formation and venous thrombosis through PKA/AKAP13/RhoA axis 1.00
6 5.93
RNA binding protein CAPRIN1 suppresses STAT1 translation and interferon signalling to promote HBV replication 0.93
CAV1-DOT1L axis in TAM-derived EVs orchestrates VM and sensitises PDAC to combined VM and VEGF targeting 1.00
Impairment of Rab7-dependent STING degradation hampers HBV replication but accelerates disease progression in chronic hepatitis B comorbid with MASLD 1.00
CD48 is a novel immune checkpoint on tumour‐associated macrophages in hepatocellular carcinoma 1.00
<atl>iParasutterella excrementihominis/i exacerbates experimental colitis and colitis-associated colorectal cancer via pathogenic NETosis activation</atl> 1.00
Enterococcus faecalis hijacks FABP2 to activate quorum-sensing signals and aggravate Crohn’s disease by inducing gut dysbiosis 1.00
4 3.83
FYN/LCK kinase balance as a metabolic switch orchestrates progenitor exhausted T Cell differentiation in hepatocellular carcinoma. 1.00
Myeloid KIF13B suppresses the STT3A/CTSD/THBS1 Axis to prevent MASH. 0.96
Tertiary lymphoid structures in hepatocellular carcinoma: Influence on immune cell profiles in tumors and on efficacy of adjuvant PD-1 inhibitor therapy after hepatectomy. 1.00
Serum amyloid A1-Induced intrahepatic regulatory T cell dysfunction drives autoimmune hepatitis progression. 0.88
13 11.06
An SPP1-SOCS1 pathway constrains interferon responses in tumor-associated macrophages and shapes an immunosuppressive tumor microenvironment 1.00
Modular double-stranded DNA recognition defines specificity of the exonuclease TREX1 in cGAS-STING control 1.00
Krüppel-like factors 2 and 3 regulate T cell exhaustion by directing T cell residency and migration 0.03
Effector differentiation by stem-like intraepithelial γδ T cells is required for host defense against infection 1.00
Exosite-mediated targeting of GSDMB by dimeric granzyme A in lymphocyte pyroptotic killing 1.00
The TCR-SUB1-DOCK2 axis promotes autoimmunity by driving pathogenic CD4+ T cell tissue infiltration 0.83
A chemical agonist and the Golgi-resident lipid PI4P activate STING by inducing transmembrane helix rearrangement 1.00
Membrane integrity changes upon viral infection activate sphingomyelinase SMPDL3B to restrict cGAS-STING signaling via cGAMP degradation 1.00
Spatiotemporal dynamics of CXCL10 encode contextual immune information revealed by the genetically encoded fluorescent sensor 1.00
Structures of butyrophilin multimers reveal a plier-like mechanism for Vγ9Vδ2 T cell receptor activation 1.00
A CD4+ T cell-intrinsic complement C5aR2-prostacyclin-IL-1R2 axis orchestrates Th1 cell contraction 0.20
Maternal natural killer cells drive neuroimmune disorders in offspring through aberrant secretion of extracellular granzyme B 1.00
Phosphoantigen-induced inside-out stabilization of butyrophilin receptor complexes drives dimerization-dependent γδ TCR activation 1.00
2 2.00
γδ T cell exhaustion is associated with obesity in individuals with type 2 diabetes 1.00
Single-cell transcriptome atlas and genome-wide Mendelian randomization reveal chemokine involvement in diverse immune cells in type 2 diabetes 1.00
11 10.38
A unique echinoderm NLR triggers Vibrio phagocytosis by promoting microtubule severing to facilitate microfilament polymerization 1.00
RNA-binding protein tristetraprolin inhibits Th2 cell activation and differentiation in allergic rhinitis by promoting TRIM18 mRNA decay 1.00
HMGB1 Binds to and Disrupts the Hairpin Structure of RNA15 and Inhibits Toll-like Receptor Activation 0.61
The long non-coding RNA MALAT1 encodes a micropeptide that promotes influenza A virus replication by suppressing innate immune responses 0.93
Activation of stimulator of interferon genes (STING) and inhibition of vascular endothelial growth factor receptor (VEGFR) by telatinib induce antitumor activity 1.00
Dynamic control of bacterial antiphage defense through the CdnG–Cap5 cyclic oligonucleotide–based antiphage pathway in Vibrio cholerae 1.00
MARCH8-mediated ubiquitination regulates expression of the antiviral protein IFITM3 0.94
Histone Deacetylase 6 Inhibits STING-Dependent Antiviral Immunity via Site-Specific Deacetylation 0.96
IL4I1 overexpression protects against nonalcoholic fatty liver disease in part by inhibiting the AKT/FOXO1 pathway-mediated Th17 cell differentiation 1.00
Mannose-modified hemocyanin enhances pathogen endocytosis by crustacean hemocytes 0.93
An anti-CD47 antibody binds to a distinct epitope in a novel metal ion-dependent manner to minimize cross-linking of red blood cells 1.00
1 1.00
Contact-dependent incorporation of endoplasmic reticulum into retraction fibers and migrasomes 1.00
23 19.84
DYRK1A enhances antitumor immunity in type 1 conventional dendritic cells via mTORC1 activation 0.95
Estrogen receptor β deficiency increases susceptibility to sepsis through metabolic reprogramming-induced macrophage pyroptosis 1.00
A CD138+ tumor-associated macrophage-Siglec-F+ neutrophil feedforward loop promotes immune evasion in pancreatic cancer 1.00
TLR4 maintains Treg-mediated protection against adverse outcomes in a model of hepatic surgical stress 0.90
Ectopic B lymphocyte follicles exacerbate ischemic brain damage via MIF-CD74/CXCR4 and interferon signaling 0.94
GSDME/IL-18 pyroptotic axis prevents myosteatosis by expanding tissue-resident macrophages to promote muscle regeneration 1.00
PARP inhibitors restore NK cell function via secretory crosstalk with tumor cells in prostate cancer 1.00
T cell receptor-engineered T cells targeting the TP53R248Q neoantigen elicit antitumor effects in human cancer models 1.00
Tumor-derived neutrophil extracellular trap–associated DNA impairs treatment efficacy in breast cancer via CCDC25-dependent epithelial-mesenchymal transition 1.00
Mutant p53 promotes clonal hematopoiesis through generating a chronic inflammatory microenvironment 0.05
CARD9-dependent macrophage plasticity regulates effective fungal clearance 1.00
Targeting plasticity in the pyrimidine synthesis pathway potentiates macrophage-mediated phagocytosis in pancreatic cancer models 1.00
Targeting STING–induced immune evasion with nanoparticulate binary pharmacology improves tumor control in mice 1.00
Cancer-associated fibroblasts enhance colorectal cancer lymphatic metastasis via CLEC11A/LGR5-mediated WNT pathway activation 0.95
UBA1-depleted neutrophils disrupt immune homeostasis and induce VEXAS-like autoinflammatory disease in mice 1.00
Myeloperoxidase-anchored ENO1 mediates neutrophil extracellular trap DNA to enhance Treg differentiation via IFITM2 during sepsis 0.88
IGFBP6 orchestrates antiinfective immune collapse in murine sepsis via prohibitin-2–mediated immunosuppression 1.00
TET3 is a common epigenetic immunomodulator of pathogenic macrophages 0.28
CDK12/13 inactivation triggers STING-mediated anti-tumor immunity in pre-clinical models 0.11
cGAS activation converges with intracellular acidification to promote STING aggregation and pyroptosis in tumor models 1.00
Hepcidin sustains Kupffer cell immune defense against bloodstream bacterial infection via gut-derived metabolites in mice 1.00
Panose prevents acute-on-chronic liver failure by reducing bacterial infection in mice 0.94
PIEZO1 mediates mechanical reprogramming of neutrophils for proangiogenic specialization in the lung 0.85
16 10.52
Zbtb32 promotes CD8+ T cell differentiation and function in cancer 1.00
Hypoxia-inducible protein 2 mediates metabolic adaptation of Ly6ChighLy6Glow monocytes after stroke 0.85
<atl>SpeckSeq enables high-throughput functional stratification of iMEFV/i variants in autoinflammatory diseases</atl> 0.02
REV-ERB regulates RORγt+ regulatory T cell specification and function through the Bhlhe40-c-Maf axis 0.50
Tet2 deficiency–induced expansion of monocyte-derived macrophages promotes liver fibrosis 0.93
CD2 and its ligands are involved in development and activation of MAIT cells 0.08
Tumors with microsatellite instability upregulate TREX1 to escape antitumor immunity 1.00
Brain-infiltrating ILC2s boost poststroke angiogenic initiation through α-CGRP production 1.00
TLR2 supports γδ T cell IL-17A response to ocular surface commensals by metabolic reprogramming 0.03
ALK2/3 recruitment to the immunological synapse is required for T cell activation and death 1.00
Perturbation of calreticulin potentiates CD8+ T cell–mediated antitumor immunity 0.85
A CARMIL2 gain-of-function mutation suffices to trigger most CD28 costimulatory functions in vivo 0.25
BCOR and ZC3H12A suppress a core stemness program in exhausted CD8+ T cells 1.00
A multimorphic variant in ThPOK causes an inborn error of immunity with T cell defects and fibrosis 0.04
MYO1F in neutrophils is required for the response to immune checkpoint blockade therapy 1.00
PCK1 inhibits cGAS-STING activation by consumption of GTP to promote tumor immune evasion 0.97
1 1.00
Genetically engineered pig-to-human liver xenotransplantation 1.00
4 3.14
Restoration of Mucosa-Associated Invariant T-Cell Function in Healthcare-Associated Bacterial Infections Supports Recovery of Carbapenem Efficacy Against Resistant Bacteria Ex Vivo 0.31
Single-Cell Sequencing Reveals Varying Cell-Mediated Immunity Profiles in Individuals with Distinct Antibody Responses Following Ad5-nCoV Booster 1.00
Ifit1 Protects Against Lipopolysaccharide and D-galactosamine-Induced Fatal Hepatitis by Inhibiting Activation of the JNK Pathway 0.83
Mycobacterium tuberculosis PE_PGRS62 Protein Inhibits Type I Interferon Responses to Promote HIV-2 Replication by Directly Interacting With Interferon Regulatory Factor 3 1.00
3 3.00
Clinical characteristics, subtype classification, and prognostic factors of ophiasis: A retrospective study of 150 patients with therapeutic implications 1.00
Characterization and treatment outcomes of rituximab therapy in super-responders and rituximab-refractory pemphigus patients: A single-center retrospective study 1.00
Ivarmacitinib for the Treatment of Adults with Severe Alopecia Areata: Results from a Phase 3 Trial 1.00
11 10.54
Structurally Resilient Peptide Assembly Regulates Pathogenic Galectin-10 Crystallization To Mitigate Crystallopathy Inflammation 1.00
Transmembrane DNA Nanochannel-Engineered Artificial Receptors for Navigating NK Cell Immunotherapy in Solid Tumors 1.00
Chemical Synthesis of Native ADP-Ribosylated Oligonucleotides Enables Analysis of DNA ADP-Ribosylation Hydrolase Specificity 0.54
SELEX-HTCFQ Platform: Developing DNA Enhancers of ADAR1 to Suppress ZBP1-Dependent Immunopathology 1.00
A Candidalysin-Neutralizing Nanomodulator Enhances Colorectal Cancer Immunotherapy by Targeting Fungi–Macrophage Crosstalk 1.00
Responsive Photosensitizer Precursors Reverse Drug-Induced Secondary Immunosuppression 1.00
Activatable Fluorescent Probes for In Vivo and Ex Vivo Dynamic Profiling of Virus-Infected Macrophages 1.00
Genetically Engineered Biomimetic Nanoparticles for Synergistic Activation of Glioma-Associated Macrophages against Glioblastoma 1.00
NIR-Switched DNA Shutter Enables Reversible Intermittent cGAS-STING Activation for Enhanced Antitumor Immunity 1.00
Chemically Inducible Cyclic Dinucleotides as Self-Deliverable STING Agonists with Enhanced Antitumor Immunity 1.00
Spatiotemporally Resolved Imaging of Adenosine in the Mouse Brain Links Depression and Inflammation 1.00
1 1.00
CFHR3*B Haplotype, Complement Activation, and Risk of IgA Nephropathy 1.00
3 2.89
The splenic norepinephrine–β2-adrenergic receptor axis aggravates sepsis-associated acute kidney injury via neutrophil-mediated immunosuppression 1.00
Multi-omics analyses reveal the pathogenic role of terminal ileum-derived IgA+β7+ cells in IgA nephropathy 0.94
Macrophages mediate acute kidney allograft rejection via a toll-like receptor 4-dependent mechanism 0.94
3 2.92
RNA anti-CRISPRs deplete Cas proteins to inhibit the CRISPR-Cas system 1.00
Lipid-regulated phosphorylation hierarchy of the T cell receptor tyrosine motifs 0.92
MLKL activates the cGAS-STING pathway by releasing mitochondrial DNA upon necroptosis induction 1.00
4 3.87
Liver-derived complement component 3 promotes the susceptibility to stress-induced depression by impairing blood-brain barrier integrity 1.00
ATP release from the amygdala-prefrontal pathway regulates vulnerability to social stress in male mice 1.00
Comprehensive single-cell transcriptomic atlas of microglia in Alzheimer’s disease mouse models 0.94
Cerebellar microglia-derived IL-17A mitigates autism-related behavioral and synaptic deficits 0.93
1 1.00
Intervention in the Crosstalk between the cGAS-STING Pathway and Autophagy Using an Oligonucleotide-Based Bioorthogonal Platform for Amplifying Immunotherapy 1.00
8 3.42
Parasites trigger epithelial cell crosstalk to drive gut–brain signalling 0.18
SLAMF6 as a drug-targetable suppressor of T cell immunity against cancer 0.08
Agonists for cytosolic bacterial receptor ALPK1 induce antitumour immunity 1.00
Architecture of the neutrophil compartment 0.12
Amplifying antigen-induced cellular responses with proximity labelling 1.00
WSTF nuclear autophagy regulates chronic but not acute inflammation 0.03
Rescuing dendritic cell interstitial motility sustains antitumour immunity 0.98
Concurrent loss of the Y chromosome in cancer and T cells impacts outcome 0.02
4 3.74
Reinvigorating COTL1high NK cells via GITR signalling overcomes immune checkpoint blockade resistance in tsMHC-I-impaired tumours 1.00
WDR4 drives tumour-associated macrophage reprogramming and tumour progression via selective translation and membrane cholesterol efflux 0.80
CD160 dictates anti-PD-1 immunotherapy resistance by regulating CD8+ T cell exhaustion in colorectal cancer 1.00
MLKL PARylation in the endothelial niche triggers angiocrine necroptosis to evade cancer immunosurveillance and chemotherapy 0.94
1 1.00
Eukaryotic ADCY7 catalyzes the production of c-di-AMP to activate the NLRP3 inflammasome 1.00
1 0.04
Tumour-specific STING agonist synthesis via a two-component prodrug system 0.04
92 76.13
RPSA-OLFM4 axis governs neutrophil migration against bacterial infection and sepsis 1.00
A phage-encoded sponge protein suppresses bacterial TIR-Caspase immune signaling 0.83
Tree shrew immune cell atlas identifies NR1H3⁺ tissue macrophages with conserved anti-inflammatory function 1.00
Chitinase-like proteins de-N-glycosylating CD36 modify cholesterol metabolism in atherosclerotic macrophages 0.97
Dissecting PGE2-driven inhibition of T cell activation using single-cell multi-omic and inflammatory bowel disease genetic association analysis 0.11
A biomimetic nanodisc system selectively activates type I interferons by nonclassical STING pathway for cancer immunotherapy 1.00
Polymersomes preventing brain infiltration of CD177+ neutrophils to mitigate hemorrhagic transformation post-tPA thrombolysis 1.00
Molecular signatures and causal factors underlying latent cytomegalovirus infection among people living with HIV (PLHIV) 0.02
DC-CD4 bispecific tolerogenic nanovesicles induce antigen-specific regulatory T cells and ameliorate collagen-induced arthritis in mice 1.00
Spatial heterogeneity of MDSCs mediated by ANXA1-FPRs signaling drives immune suppression in OSCC progression 1.00
Reactivating exhausted tumor-infiltrating T cells by a bispecific DC-T cell engager in mice 1.00
Mining antibody functionality via AI-guided structural landscape profiling 0.14
Conducting polymer-stabilized nanozymes alleviate sepsis-induced myocardial injury by inhibiting iron accumulation and lipid peroxidation 1.00
Design of miniprotein inhibitors targeting complement C9 to block membrane attack complex assembly 1.00
NCX1 reverse mode promotes calcium-dependent Neutrophil Extracellular Trap formation and lung damage in chronic obstructive pulmonary disease 1.00
CD8 T cell loss induces autoinflammation in inborn errors of cell death 0.86
DPEP2 suppresses hyperinflammation via metabolic reprogramming of macrophages in sepsis 1.00
Chromatin-intrinsic mechanisms determine orientation-specific class switch recombination 1.00
Tumor-associated CD19 macrophages induce immunosuppressive microenvironment in hepatocellular carcinoma 1.00
Stem-like memory-T maintenance and differentiation into tissue-resident T cells sustain chronic graft-versus-host disease in mice 0.07
The landscape of tissue-resident microbiota across normal, polyp, and colorectal cancer tissues 1.00
A multi-center clinical trial of allogeneic hematopoietic stem cell transplantation in transfusion-dependent thalassemia 0.93
Telomeric repeat-containing RNA G-quadruplexes trigger ZBP1-mediated cell death 1.00
The transcription factor EHF promotes the maturation and immunosuppression of conventional dendritic cells 1.00
RORγt APCs require a distinct cis-regulatory element to instruct tolerance to dietary antigens 0.82
Dipeptidylpeptidase 4 inhibition attenuates gestational pathologies via immune homeostasis restoration in the pulmonary-uterine axis 1.00
Deficiency of lysosomal TMEM175 in myeloid macrophages exerts anti-tumor immunity via inflammasome and cross-presentation pathway 1.00
Triple targeting of STING, TGF-β, and PD-L1 boosts CXCL16–CXCR6 signaling for potent antitumor response 1.00
CD38 degrades MAVS through mitophagy to inhibit type I interferon secretion in nasopharyngeal carcinoma cells and impairs CD8+T cell-mediated anti-tumor immunity 1.00
Gut microbiota-derived butyrate primes systemic immunity in honey bees by mediating lipid metabolic reprogramming 1.00
Circadian fluctuation of soluble CD26 dictates the impact of the timing of cord blood transplantation on acute graft-versus-host disease 1.00
A spatially resolved atlas of gastric cancer characterises a lymphocyte-aggregated region 1.00
Shigella flexneri evades septin-mediated cell-autonomous immunity via protein ADP-riboxanation 0.82
A DNA-based nanodevice senses purinergic signaling and drives an immune switch for resolving inflammation 1.00
SAMSN1 restrains NK cell mediated anti-tumor immunity in hepatocellular carcinoma 1.00
GBP2 condensates promote ferroptosis to sensitize anti-PD-L1 immunotherapy in melanoma 1.00
Integrating protein language and geometric deep learning models for enhanced vaccine antigen prediction 1.00
Resistance potential of the HLA-A2-restricted immunodominant SARS-CoV-2-specific CD8+ T cell receptor repertoire to antigenic drift 0.25
Genetic and dietary determinants of gut microbiome-bile acid interactions in the BXD genetic reference population 0.05
Agonist signaling drives neutrophil subpopulations to promote/inhibit colorectal cancer liver metastasis 1.00
The long non-coding RNA UGDH-AS1 encodes an NK-cell-inhibiting micropeptide in triple-negative breast cancers 1.00
Chimeras co-targeting antigens and FcγRIIb trigger degradation of extracellular soluble proteins and pathological aggregates 1.00
Structural insights into clonal restriction and diversity in T cell recognition of two immunodominant SARS-CoV-2 nucleocapsid epitopes 0.64
Human pluripotent stem cell-derived skin organoids enabled pathophysiological model of infection 1.00
mTORC1 signaling in group 2 innate lymphoid cells coordinates neuro-immune crosstalk in allergic lung inflammation 1.00
Deleterious variants in the autophagy-related gene /FIP200 impair immunity to SARS-CoV-2 0.01
A biomimetic senotherapy replenishing MAT2A promotes wound regeneration in preclinical models 1.00
Atomic mechanisms of full-length ASC-mediated inflammasome assembly 0.88
Lysosomal acidity and cathepsin L activate eosinophils via ARG1-mediated arginine metabolism in allergic airway inflammation 1.00
Silencing PCSK9 reshapes the spatiotemporal activation of STING for safe and effective cancer immunotherapy 1.00
Single-cell and spatial transcriptomics implicate a prognostic function of tertiary lymphoid structures in gastric cancer 1.00
Palmitoylation of TBK1 enhances the type I interferon signaling and strengthens anti-malarial immunity in mice 1.00
Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection 0.01
Human intestinal fungus attenuates colitis through Pyruvate decarboxylase-derived Indole-3-ethanol 1.00
Paraventricular nucleus CRH neurons regulate acute lung injury via sympathetic nerve–neutrophil axis 0.80
A loss-of-function human ADAR variant activates innate immune response and promotes bowel inflammation 0.22
Mechano-crosstalk between living and artificial cells 0.89
A newborn derived monoclonal IgM antibody selectively modulates microbial metabolism in the gut 1.00
Autonomous artificial intelligence prescribing a drug to prevent severe acute graft-versus-host disease in HLA-haploidentical transplants 0.98
AEBP1 drives fibroblast-mediated T cell dysfunction in tumors 1.00
Prefoldin complex promotes interferon-stimulated gene expression and is inhibited by rotavirus VP3 0.08
scIVNL-seq resolves in vivo single-cell RNA dynamics of immune cells during infection 1.00
Interferon-stimulated gene screening identifies CCND3 as a host restriction factor against emerging high-pathogenic bandaviruses 1.00
SARS-CoV-2 antibody responses in children exhibit higher FcR engagement and avidity than in adults 0.77
Regulatory T cell therapy promotes TGF-β and IL-6-dependent pro-inflammatory Th17 cell generation by reducing IL-2 0.84
H2A.Z primes an epigenetic landscape for memory CD8 T cell recall response 1.00
A citrullinated histone H3 monoclonal antibody for immune modulation in sepsis 0.10
Epigenetic modulation with nanosatellite triggers tumoricidal immunity for hepatocellular carcinoma treatment 1.00
Development of conformation-selective antibodies targeting human SLC15A4 1.00
Structural insights into polymerase-catalyzed FAD capping of hepatitis C virus RNA 1.00
TLR4group 2 innate lymphoid cells contribute to persistent type 2 immunity in airway diseases 0.83
The RNA-binding protein RRP1 brakes macrophage one-carbon metabolism to suppress autoinflammation 1.00
Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice 0.94
Enrichment of decidual CD11c + CD8 + T cells with altered immune function in early pregnancy loss 1.00
Calcium-dependent oligomerization of scavenger receptor CD163 facilitates the endocytosis of ligands 1.00
Targeting CD37 promotes macrophage-dependent phagocytosis of multiple cancer cell types and facilitates tumor clearance in mice 0.91
Antigen specificity shapes distinct aging trajectories of memory CD8⁺ T cells 0.03
Mast cells boost anti-tumor potency of MAIT cells via inflammasome-dependent secretion of IL-18 1.00
Budesonide-incorporated inhalable lipid nanoparticles for antiTSLP nanobody mRNA delivery to treat steroid-resistant asthma 0.60
Elevated nitric oxide during colitis restrains GM-CSF production in ILC3 cells via suppressing an AhR-Cyp4f13-NF-κB axis 1.00
Viruses hijack FPN1 to disrupt iron withholding and suppress host defense 1.00
Identifying T cell antigen at the atomic level with graph convolutional network 1.00
Polyketide synthase-derived sphingolipids mediate microbiota protection against a bacterial pathogen in C. elegans 0.03
Dietary advanced glycation end-products promote food allergy by disrupting intestinal barrier and enhancing Th2 immunity 0.92
Oral ENPP1 inhibitor designed using generative AI as next generation STING modulator for solid tumors 0.86
Comparative duration of neutralizing responses and protections of COVID-19 vaccination and correlates of protection 0.80
USP2 inhibition unleashes CD47-restrained phagocytosis and enhances anti-tumor immunity 1.00
Targeting Setdb1 in T cells induces transplant tolerance without compromising antitumor immunity 0.94
Blocking plasma cell fate enhances antigen-specific presentation by B cells to boost anti-tumor immunity 0.18
Mature tertiary lymphoid structures evoke intra-tumoral T and B cell responses via progenitor exhausted CD4+ T cells in head and neck cancer 1.00
A high-performance fluorescent sensor spatiotemporally reveals cell-type specific regulation of intracellular adenosine in vivo 1.00
PWWP3A disrupts the assembly of VISA/MAVS signalosome to inhibit innate immune response against RNA viruses 1.00
1 0.40
ADAR1 editing is necessary for only a small subset of cytosolic dsRNAs to evade MDA5-mediated autoimmunity 0.40
25 14.10
Cytosolic CTH senses bacterial lipoproteins and drives noncanonical inflammasome activation 1.00
IL-9 and Blimp-1 protect the transcriptional identity of group 2 innate lymphocytes in allergic asthma 0.05
Immunopeptidome profiling in pulmonary fibrosis provides a platform for identifying therapeutic targets 0.92
BLIMP1 shapes germinal center B cell clonal diversity by gating chromatin accessibility during light-to-dark zone transition 0.14
A unique CD4⁺ T cell subset expressing granzyme K is regulated by transcription factor EOMES and important for T cell-mediated intestinal inflammation 1.00
Targeting NK cell CLEC12B enhances cancer immunotherapy 1.00
Lipid asymmetry disruption by XKR8 orchestrates neutrophil extracellular trap formation and inhibits fungal infection 1.00
HLA class I signal peptide variation predicts strength of NKG2A NK cell response to missing-self and risk of human disease 0.08
Sparcl1 mitigates abdominal aortic aneurysm through inhibiting lymphangiogenesis-mediated TLS formation 1.00
Lymphocyte-derived cholinergic circuits modulate germinal center output and B cell activation 0.04
Temporal and spatial atlas of eosinophil specialization across tissues 0.84
The IL17REL gene encodes a decoy receptor of IL-17 family cytokines to control gut inflammation 1.00
Targeting autocrine retinoic acid signaling by ALDH1A2 inhibition enhances antitumor dendritic cell vaccine efficacy 0.07
Antigen reactivity defines tissue-resident memory and exhausted T cells in tumors 0.01
Adenophages are an atypical macrophage population in exocrine glands sustained by ILC2-derived GM-CSF 0.08
DC subsets and states unraveled across human juxtatumoral and malignant tissues 0.01
Sequential lymphotoxin-β receptor and retinoic acid receptor signals regulate cDC2 fate 0.02
Chemotherapy-induced CA-repeat DNA fragments in breast cancer trigger antitumor immune responses 1.00
STING signals to NF-κB from late endolysosomal compartments using IRF3 as an adaptor 0.01
Epigenetic imprinting in innate lymphoid cell precursors directs the lineage segregation of innate lymphoid cells 1.00
E3 ligase RAD18 targets phosphorylated IRF3 to terminate IFNB1 transcription 1.00
SATB1 is a key regulator of quiescence in stem-like CD8 T cells 0.03
Transcription factors TCF4 and KLF4 respectively control the development of the DC2A and DC2B lineages 0.85
Neuroprotective liver portal area macrophages attenuate hepatic inflammation 1.00
CARD11 signaling regulates CD8+ T cell tumoricidal function 0.94
4 2.89
Low-dose oral nicotinamide mononucleotide for immune thrombocytopenia: a phase 1/2 trial 1.00
Pig-to-human lung xenotransplantation into a brain-dead recipient 0.85
Immune cell landscape in a human decedent receiving a pig liver xenograft 1.00
A microRNA-based dynamic risk score for type 1 diabetes 0.04
1 0.91
Genetically encoded biosensor for monitoring spatiotemporal dynamics of CCR2 ligands in culture and in vivo 0.91
1 0.07
Engineered mucus-tethering bispecific nanobodies enhance mucosal immunity against respiratory pathogens 0.07
1 0.94
More than microglial depletion: PLX5622 activates the hepatic constitutive androstane receptor to alter anesthesia and addiction 0.94
1 1.00
An Integrated Solubilizing-Tag-Free Strategy for Chemical Synthesis of Mirror-Image Interleukin-6 1.00
3 2.03
Structure of the human P2X3 receptor reveals the basis for subtype-selective inhibition by sivopixant 1.00
Specificity and recognition of the ADP-ribosyl-ubiquitin modification in the DNA damage response 0.03
Mediator complex subunit MED23 dampens antiviral innate immunity by restricting RIG-I expression 1.00
1 0.83
Optimal Distributions of Receptors on Arbitrarily Shaped Cell Surfaces 0.83
37 28.04
Cytochrome P450 1B1 directs pathogenic Th17 cell generation and autoimmune disease by fine-tuning redox homeostasis and mitochondrial integrity 1.00
An Ad5-vectored platform generating self-assembling VLPs elicits potent mucosal immunity against influenza A virus and SARS-CoV-2 0.98
TLR1 deficiency associates with immune dysregulation and colitis 1.00
SCD1 licenses STING signaling through fatty acid desaturation–mediated membrane remodeling 1.00
WFDC21P is essential for G3BP1-mediated RIG-I activation and antitumor immunity in triple-negative breast cancer 1.00
Monkeypox virus protein OPG188 antagonizes cGAS–STING antiviral signaling pathway to mediate immune evasion 1.00
N6-methyladenosine modification of FZR1 mRNA positively regulates antiviral innate immunity by targeting the MAVS–TRAF3/6 axis 1.00
The Crohn’s disease–related RNF123 prevents NLRP3 inflammasome assembly by catalyzing unanchored K63-linked ubiquitination on NEK7 1.00
Engineering chimeric antigen receptor CD4 T cells for Alzheimer’s disease 0.11
FcγRIIB functions as an IgG transporter in the mammary gland 0.90
Broad beta-CoV immunity and transmission blockade by a single-dose live-attenuated vaccine with atypical codon usage 0.74
α2-macroglobulin function of thioester-containing proteins guards Drosophila from a bacterial protease via two immune-induced peptides 0.29
Multiomics identifies a cholesterol–TFEB–PLD3–TLR9 axis driving immunosuppressive tumor-associated macrophage polarization in esophageal squamous cell carcinoma 1.00
A PSAT1 buff of YBX1 transcriptionally sustains HLA-E-mediated evasion of NK immunity 0.94
Endogenous forms of ATP–ATP4− and MgATP2−—orchestrate distinct pathophysiological signaling via biased activation of P2X3 receptors 1.00
Modulation of the PGRMC1/NLRP7/HLA-C axis by autophagy is linked to both spontaneous preterm birth and gestational choriocarcinoma 0.92
Engineering a spatiotemporal macrophage circuit via STING phase separation to override immune suppression in pancreatic cancer 0.94
A binary-distributed effector modulates fungal host preference for drosophilids by targeting a lineage-specific immune factor 1.00
eATP sensing by the purinergic receptor PA2072 for allosteric modulation in intracellular c-di-GMP signaling 1.00
TCR signal–enhancing mutation alters lipid metabolism of thymocytes and impairs antitumor immunity of mature T cells 1.00
TMEM16F phospholipid scramblase regulates tumorigenesis by modulating the tumor immune microenvironment 1.00
Linking the production of reactive oxygen species to the expression of antimicrobial peptides through aquaporin in an arthropod 1.00
The integrated stress response suppresses antiviral RNA interference by autophagy-mediated degradation of the RNA-induced silencing complex 1.00
Regulation of an lncRNA irf8 by the Ikzf1/Myb complex drives neutrophil development 1.00
The Arabidopsis TIRome informs the design of artificial TIR (Toll/interleukin-1 receptor) domain proteins 0.06
Inflammation awakens dormant cancer cells by modulating the epithelial–mesenchymal phenotypic state 0.22
HLA-B*15:01-positive severe COVID-19 patients lack CD8+ T cell pools with highly expanded public clonotypes 0.29
ER-resident CCDC134 safeguards TLR4 maturation by maintaining gp96 stability 0.80
Regulation of CD45 isoforms during human effector and memory CD8 T cell differentiation: Implications for T cell nomenclature 0.08
SARS-CoV-2 infection induces ZBP1-dependent PANoptosis in bystander cells 1.00
Common inherited loss-of-function mutations in the innate sensor NOD2 contribute to exceptional immune response to cancer immunotherapy 0.03
DNA2 protein destruction dictates DNA hyperexcision, cGAS–STING activation, and innate immune response in CDK12-deregulated cancers 0.46
The transcription factor Bcl11a is essential for B-1a cell maintenance during aging 1.00
RACK1 promotes the development and function of alveolar macrophages through directly binding to and stabilizing PPARγ 1.00
Nanoimmunomodulation of the Aβ-STING feedback machinery in microglia for Alzheimer’s disease treatment 1.00
Induction of the ISR by AB5 subtilase cytotoxin drives type-I IFN expression in pDCs via STING activation 0.11
Hdac1 as an early determinant of intermediate-exhausted CD8+ T cell fate in chronic viral infection 0.19
1 0.20
Functional characterization of Paillotin: an immune peptide regulated by the Immune deficiency (Imd) pathway with pathogen-specific roles in Drosophila immunity. 0.20
4 1.29
Macrophage MR1 antigen presentation promotes MAIT cell immunity and lung microbiota modulation 0.02
Ms4a7 expression in cDC1s determines cross-presentation and antitumor immunity 1.00
MTAP deficiency confers resistance to cytosolic nucleic acid sensing and STING agonists 0.21
Type 2 cytokines act on enteric sensory neurons to regulate neuropeptide-driven host defense 0.06
23 18.13
RNA binding protein Pcbp1 maintains mitochondria integrity to promote antibody production and germinal center response 1.00
Dissection of the T cell infiltrate in mouse pancreatic tumors reveals an extensive and diverse tumor-reactive T cell repertoire 0.03
PROTAC-based synthetic lethality strategy endogenously activates systemic STING to boost antitumor immunity 1.00
The conserved noncoding sequence CNS11 is a master control region for Rorc transcription in type 17 immune cells 1.00
12R-HETE acts as an endogenous ligand for Nur77 in the intestines and regulates NKp46+ ILC3 development 1.00
Complement C3 recognition by C3 convertases 1.00
Magnetoelectric nanoparticles drive TAF9B+ TH2 cell expansion to alleviate inflammation 1.00
RSV temporally reprograms apoptosis and pyroptosis to balance immune evasion and replication 1.00
CXCR5 identifies stem-like resident memory CD8⁺ T cells enriched for latent EBV specificity in tonsils 0.02
Human FcRL5 is an Fc receptor that simultaneously engages two IgGs 1.00
VNUT-mediated ATP release suppresses T helper 1 (TH1) cell differentiation via the P2X7R-JNK-FOXO3a-Eomes signaling cascade 1.00
Decoding the CHI3L1/IL-13Rα2 signaling nexus in MASH-fibrosis pathogenesis 1.00
Droplet-based single-cell pairing for high-throughput interaction mapping of antigen-receptor combinations 1.00
VAPB is a negative regulator of STING-mediated innate immune signaling 0.89
Ligand-receptor interactions induce and mediate regulatory functions of BATF3+ B cells 0.09
STK11 coordinates IL-4 signaling with metabolic reprogramming to control M2 macrophage polarization and antitumor immunity 0.05
Endoplasmic reticulum junctions serve as a platform for endosome-lysosome interactions through their stop-and-go motion switching 1.00
CD8+HLA-DR+CD27+ T cells define a population of naturally occurring regulatory precursors in humans 1.00
Prdm12 governs an epigenetic checkpoint linking neuroimmune cross-talk to CD8+ T cell exhaustion-suppressed antitumor immunity 1.00
BACH2 drives the development and function of group 2 innate lymphoid cells 1.00
Modulating immune cell fate and inflammation through CRISPR-mediated DNA methylation editing 0.06
Sphingolipid synthesis in tumor-associated macrophages confers immunotherapy resistance in hepatocellular carcinoma 1.00
Immunopeptidomics-guided discovery and characterization of neoantigens for personalized cancer immunotherapy 1.00
8 6.86
Pharmacological activation of WASp potentiates macrophage phagocytosis and enhances ibrutinib efficacy against mouse models of brain tumors 1.00
A peptide immunomodulator activates MST1 to expand and stabilize murine and human regulatory T cells for immune tolerance 1.00
FcγR-targeted tuftsin clusters rejuvenate macrophages in preclinical sepsis–associated secondary infection 1.00
PIEZO1-activated donor lymphatic remodeling integrates with autologous lymphangiogenesis to enhance vein graft patency in mice 0.95
S100A8/A9 perturbation in bone marrow blunts antitumor immunity by promoting protumorigenic myelopoiesis in mouse models 1.00
Myeloid MAS–driven macrophage efferocytosis promotes resolution in ischemia-stressed mouse and human livers 1.00
Synthetic biology–driven induction of mature TLS formation enhances antitumor immunity in colorectal cancer 0.89
Gasdermin D drives the systemic storm and mortality after trauma with hemorrhage to a greater degree in biological females than males 0.02
1 1.00
Anti-CD38 monoclonal antibody CM313 for primary immune thrombocytopenia: multicentre, randomised, placebo controlled, phase 2 trial 1.00
5 3.47
Mechanistic basis for selective Csm6-2 activation by cyclic penta-adenylate in a type III CRISPR-Cas system 1.00
FADD is recruited to activated STING oligomers to initiate caspase-mediated NF-κB activation in Drosophila melanogaster 0.31
Arthropod exosomal glycine-rich protein as a potential vaccine candidate effectively reduces tick blood-feeding and pathogen transmission 0.17
The lysosomal LAMTOR-Rag complex functions as a checkpoint for antiviral interferon production 1.00
Nuclear glycine decarboxylase suppresses STAT1-dependent MHC-I and promotes cancer immune evasion. 1.00
1 1.00
Silibinin-derived microbiota enrich (R)-2,3-dihydroxy-isovalerate and ameliorate colitis via the GAT-3/RARβ/RORγt axis 1.00
3 1.61
Complement C3 links epithelial remodeling and macrophage metabolic reprogramming in allergic rhinitis 0.55
A clinically validated assay for rapid determination of type I and type II interferon activity in systemic inflammatory diseases 0.06
Preclinical and Phase I Randomized Study of a Potent Inhalable Nanobody Targeting TSLP for the Treatment of Airway Inflammation 1.00
1 0.07
Oral iptacopan therapy in patients with C3 glomerulopathy: a randomised, double-blind, parallel group, multicentre, placebo-controlled, phase 3 study 0.07
3 0.40
A Phase 2 Randomized Trial of Mezagitamab in Primary Immune Thrombocytopenia 0.08
Iptacopan in IgA Nephropathy — Final 24-Month Data 0.21
Ianalumab plus Eltrombopag in Immune Thrombocytopenia 0.12

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