Aging and Quality of Life in Multiple Sclerosis
Summary
As the life expectancy of individuals with multiple sclerosis (MS) increases, understanding how ageing interacts with disease progression and quality of life has become a priority. Ageing with MS entails not only the accumulation of neurological impairment but also the reframing of personal identity, functional ability and psychosocial well-being. Physical challenges such as mobility decline, fatigue and comorbidities frequently compound the lifelong burden of demyelination and neurodegeneration. At the same time, many older adults with MS report adaptive strategies, resilience and a renewed sense of purpose that mitigate adversity. Emerging evidence underscores the importance of multidimensional care models that integrate neurological assessment, rehabilitation, mental health support and personalised self-management. Recognising the interplay between biological ageing and individual life narrative is essential to optimise health outcomes and foster meaningful engagement in later life for people living with MS.
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Aging and Quality of Life in Multiple Sclerosis publication trend
The graph below shows the total number of articles in aging and quality of life in multiple sclerosis across all publications each year (not limited to Nature Index journals).
Technical terms
Expanded Disability Status Scale (EDSS): A standardised measure quantifying neurological impairment and functional disability in multiple sclerosis.
Biographical aging: A narrative framework emphasising how individuals’ life histories and personal meaning influence their experience of later life with chronic illness.
Wellness-oriented model of health: A perspective that prioritises functional ability, psychological well-being and social engagement over solely clinical or biomedical indicators.
References
- Unfolding biographies—a participatory narrative study on how older adults with multiple sclerosis make sense of and manage their everyday lives. BMC Geriatrics (2023).
- The meaning of health to persons aging with longstanding multiple sclerosis. Research in Nursing & Health (2024).
- Multiple Sclerosis in Mongolia; the First Study Exploring Predictors of Disability and Depression in Mongolian MS Patients. Pathophysiology (2023).
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