Ayurvedic Genomics and Personalized Medicine
Summary
Ayurvedic genomics, often termed Ayurgenomics, represents an interdisciplinary endeavour to integrate the millennia-old principles of individual constitution in Ayurveda with contemporary genomic science. Central to classical Ayurveda is the concept of Prakriti, a person’s inherent physiological and psychological constitution, determined by the relative dominance of three doshas—Vata, Pitta and Kapha. Modern researchers have begun to map these constitutional types onto genomic and molecular profiles, seeking correlations between Prakriti categories and gene expression, biochemical markers and epigenetic signatures. Such efforts aim to validate traditional diagnostic methods, refine risk stratification for complex diseases and develop truly personalised preventive and therapeutic regimens. By combining genome-wide transcriptomics, metabolomics and systems biology approaches with Ayurvedic phenotyping, the field aspires to bridge holistic paradigms and reductionist frameworks, ultimately contributing to precision health strategies that respect both individual variability and cultural heritage.
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Ayurvedic Genomics and Personalized Medicine publication trend
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Technical terms
Prakriti: The Ayurvedic classification of an individual’s innate constitution based on the balance of three doshas.
Dosha: Fundamental bioenergetic forces (Vata, Pitta, Kapha) that govern physiological and psychological functions.
Ayurgenomics: An emerging discipline that correlates Ayurvedic constitutional types with genomic and molecular profiles.
Epigenetics: The study of heritable changes in gene expression that occur without alterations in the DNA sequence, often influenced by environment and lifestyle.
Transcriptomics: The analysis of complete sets of RNA transcripts produced by the genome under specific conditions or in specific cell types.
References
- Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda. Journal of Translational Medicine (2008).
- Ayurgenomics and Modern Medicine. Medicina (2020).
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