Bioactive Compound Evaluation in Citrus Bergamia Products
Summary
Bergamot (Citrus bergamia) is rich in diverse bioactive compounds including flavonoids, phenolic acids and limonoids, which contribute to its nutraceutical potential. Research has focused on understanding the qualitative and quantitative profiles of these constituents across different product matrices such as juice, essential oil, peel extracts and processing by-products. Analytical techniques such as high-performance liquid chromatography and mass spectrometry have elucidated the compositional complexity, revealing key compounds like neoeriocitrin, naringin and neohesperidin. The bioactivities of bergamot-derived preparations encompass antioxidant, anti-inflammatory and lipid-modulating effects, with implications for metabolic syndrome, cardiovascular health and neuroprotection. Sustainable exploitation of bergamot waste streams—pomace and pastazzo—has enabled the recovery of valuable phytochemicals through green extraction methods, enhancing circular economy approaches. Ongoing efforts aim to standardise extraction protocols, optimise bioavailability and validate health outcomes in preclinical and early clinical models.
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Bioactive Compound Evaluation in Citrus Bergamia Products publication trend
The graph below shows the total number of articles in bioactive compound evaluation in citrus bergamia products across all publications each year (not limited to Nature Index journals).
Technical terms
Flavonoids: Polyphenolic compounds with a core structure of two benzene rings connected by a pyran ring, known for antioxidant and anti-inflammatory properties.
Polyphenols: A broad class of plant secondary metabolites containing multiple phenolic units, contributing to radical scavenging and health benefits.
Limonoids: Triterpenoid derivatives found in citrus that exhibit antioxidant, lipid-regulating and potential anticancer activities.
Pomace: The solid residue remaining after juice extraction, encompassing peel, pulp and seeds, often rich in bioactive constituents.
Green extraction: Environmentally friendly techniques that minimise solvent and energy use, aimed at sustainable recovery of phytochemicals from plant matrices.
References
- Quality Evaluation of Bergamot Juice Produced in Different Areas of Calabria Region. Foods (2024).
- Chemical, Nutritional and Biological Evaluation of a Sustainable and Scalable Complex of Phytochemicals from Bergamot By-Products. Molecules (2023).
- Recovery of Bioactive Compounds from Calabrian Bergamot Citrus Waste: Selection of Best Green Extraction. Agriculture (2023).
- Bergamot (Citrus bergamia) peel extract as new hypocholesterolemic agent modulating PCSK9 expression. Journal of Functional Foods (2023).
- Protective Role of an Extract Waste Product from Citrus bergamia in an In Vitro Model of Neurodegeneration. Plants (2023).
- Evaluation of Flavonoids and Furanocoumarins from Citrus bergamia (Bergamot) Juice and Identification of New Compounds. Molecules (2008).
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