Bioactive Properties of Coriandrum Sativum Extracts
Summary
Coriandrum sativum, commonly known as coriander, yields extracts rich in diverse bioactive constituents including polyphenols, flavonoids, essential oils and phytosterols. These compounds confer antioxidant, anti-inflammatory, antimicrobial and antihypertensive properties that underpin a broad spectrum of therapeutic applications. Polyphenolic fractions attenuate oxidative stress by scavenging free radicals and modulating cellular redox status, while specific flavonoids such as quercetin and kaempferol contribute to antidiabetic and cardioprotective effects via enzyme inhibition and signalling‐pathway regulation. Essential oil components (notably linalool, γ-terpinene and α-pinene) demonstrate hepatoprotective and neuroprotective actions through the induction of cytoprotective genes and the inhibition of apoptotic cascades. Further, seed and leaf extracts exhibit antimicrobial and antiparasitic activity against a range of pathogens, and novel compounds from fruits exert potent anti-inflammatory effects by targeting NF-κB and MAPK pathways. Collectively, these findings establish coriander extracts as versatile functional ingredients with global significance for nutrition, pharmacology and sustainable agriculture.
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Bioactive Properties of Coriandrum Sativum Extracts publication trend
The graph below shows the total number of articles in bioactive properties of coriandrum sativum extracts across all publications each year (not limited to Nature Index journals).
Technical terms
Polyphenols: A class of plant secondary metabolites characterised by multiple phenolic rings, known for antioxidant and enzyme-modulating activities.
Flavonoids: Subgroup of polyphenols with a common benzopyran structure, encompassing compounds such as quercetin and kaempferol, implicated in anti-inflammatory and cardioprotective effects.
Essential oil: Volatile, lipophilic compounds extracted from plant tissues, rich in monoterpenes and sesquiterpenes, with broad pharmacological properties.
Nrf2/HO-1 signalling pathway: A cytoprotective mechanism wherein Nrf2 transcription factor induces heme oxygenase-1 expression to counter oxidative stress and inflammation.
Angiotensin-converting enzyme (ACE) inhibitor: Molecule that blocks ACE activity, reducing angiotensin II production and thereby lowering blood pressure and improving cardiovascular function.
References
- Coriander (Coriandrum sativum) Polyphenols and Their Nutraceutical Value against Obesity and Metabolic Syndrome. Molecules (2023).
- Coriander essential oil attenuates dexamethasone-induced acute liver injury through potentiating Nrf2/HO-1 and ameliorating apoptotic signaling. Journal of Functional Foods (2023).
- Coriandrum sativum L.: A Review on Ethnopharmacology, Phytochemistry, and Cardiovascular Benefits. Molecules (2021).
- Antioxidant, Anti-Inflammatory and Antidiabetic Proprieties of LC-MS/MS Identified Polyphenols from Coriander Seeds. Molecules (2021).
- Novel compounds in fruits of coriander (Coşkuner & Karababa) with anti-inflammatory activity. Journal of Functional Foods (2020).
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