Cognitive Effects of Stress-Related Exhaustion

Summary

Stress-related exhaustion manifests as a marked decline in cognitive performance, affecting memory, attention, executive control and processing speed. Individuals often report difficulties in concentrating, retrieving information and sustaining mental effort, which can persist long after the acute stressor has abated. Research indicates that these deficits are not solely subjective complaints but are corroborated by objective testing and neuroimaging findings. Impairments appear most pronounced in tasks requiring rapid information updating, complex problem-solving and sustained attention. Concurrently, structural alterations in subcortical regions implicated in cognitive control, notably the striatum, have been linked to mental fatigue and its impact on working memory. The persistence of cognitive symptoms can impede daily functioning, reduce work capacity and diminish quality of life, underscoring the need for early detection, tailored interventions and rehabilitative strategies that address both psychological and neural dimensions of exhaustion.

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Cognitive Effects of Stress-Related Exhaustion publication trend

The graph below shows the total number of articles in cognitive effects of stress-related exhaustion across all publications each year (not limited to Nature Index journals).

Technical terms

Exhaustion Disorder: A stress-related condition characterised by extreme fatigue, reduced stress tolerance and cognitive impairments beyond normal burnout.

Executive Functions: Higher-order cognitive processes including planning, inhibition, mental flexibility and updating of information.

Episodic Memory: The ability to encode, store and retrieve personal events and experiences.

Working Memory: The capacity to temporarily hold and manipulate information for cognitive tasks.

Striatum: A subcortical brain structure, comprising the caudate nucleus and putamen, involved in cognitive control and mental fatigue.

References

  1. Objective cognitive functioning in patients with stress-related disorders: a cross-sectional study using remote digital cognitive testing. BMC Psychiatry (2023).
  2. Cognitive function in clinical burnout: A systematic review and meta-analysis. Work & Stress (2021).
  3. Mental fatigue in stress-related exhaustion disorder: Structural brain correlates, clinical characteristics and relations with cognitive functioning. NeuroImage Clinical (2020).
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