Electrochemical Biosensing for Antioxidant Capacity Evaluation
Summary
Electrochemical biosensing harnesses the specificity of biological recognition elements—such as enzymes, antibodies or DNA—with the sensitivity of electrochemical transducers to quantify antioxidant capacity. By monitoring redox reactions at an electrode surface, these devices provide rapid, sensitive and cost-effective assessment of both total antioxidant capacity and individual antioxidant species. Key techniques include cyclic voltammetry, square-wave voltammetry and chronoamperometry, often applied on miniaturised platforms such as screen-printed electrodes. Advances in nanomaterial-based electrode modification, enzyme immobilisation and microfabrication have improved detection limits, selectivity and operational stability. Applications span quality control in foods and beverages, clinical evaluation of oxidative stress markers in biological fluids and screening of plant-derived phytochemicals. The integration of portable and multiplexed systems addresses global needs for on-site, point-of-care analyses, facilitating real-time monitoring in diverse settings.
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Electrochemical Biosensing for Antioxidant Capacity Evaluation publication trend
The graph below shows the total number of articles in electrochemical biosensing for antioxidant capacity evaluation across all publications each year (not limited to Nature Index journals).
Technical terms
Electrochemical biosensor: A device combining a biological recognition element with an electrochemical transducer to convert biochemical interactions into measurable electrical signals.
Antioxidant capacity: A quantitative measure of the ability of a sample to neutralise free radicals or reactive species, indicating its potential to prevent oxidative damage.
Voltammetry: An electrochemical technique in which current is measured as a function of applied potential to characterise redox-active species.
Screen-printed electrode (SPE): A disposable electrode fabricated by printing conductive inks onto a substrate, used for rapid and low-cost electrochemical measurements.
References
- Electrochemical Characterization of the Antioxidant Properties of Medicinal Plants and Products: A Review. Molecules (2023).
- A Review on Electrochemical Sensors and Biosensors Used in Assessing Antioxidant Activity. Antioxidants (2022).
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