Impact of Environmental Factors on Allergic Rhinitis Symptoms

Allergic rhinitis is an immunoglobulin E–mediated inflammatory disorder of the nasal mucosa characterised by sneezing, rhinorrhoea, nasal congestion and pruritus. Environmental factors play a central role in modulating symptom severity and disease prevalence. Aeroallergens such as pollens, mould spores, house dust mites and animal dander act as primary triggers, their abundance and distribution governed by seasonal and meteorological variables including temperature, humidity and wind speed. Concurrent exposure to air pollutants—particularly fine particulate matter (PM2.5), ozone and nitrogen dioxide—can exacerbate mucosal barrier dysfunction, amplify inflammatory signalling and enhance sensitisation to allergens. Urbanisation and climate change have been linked to prolonged pollen seasons and increased allergenic potency, thereby extending the duration of symptom burden. Conversely, non-drug approaches such as face masks, barrier gels and air filtration systems can reduce allergen delivery to the nasal epithelium, offering accessible strategies to mitigate symptoms. Integrating knowledge of ambient exposures with individual avoidance and public health measures underpins effective management and highlights the global significance of environmental control in allergic disease.

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Impact of Environmental Factors on Allergic Rhinitis Symptoms publication trend

The graph below shows the total number of articles in impact of environmental factors on allergic rhinitis symptoms across all publications each year (not limited to Nature Index journals).

Technical terms

Aeroallergen: A microscopic airborne particle (such as pollen or mould spore) capable of eliciting an allergic response upon inhalation.

Type I hypersensitivity: An immediate allergic reaction mediated by IgE antibodies that leads to mast cell degranulation and histamine release.

Particulate matter (PM2.5): Fine inhalable particles with aerodynamic diameter ≤2.5 µm that can carry allergens and pollutants deep into the airways.

FFP2 mask: A filter facepiece respirator standard for filtering at least 94 % of airborne particles, including fine aerosols and pollen.

References

1. Face masks suitable for preventing COVID-19 and pollen allergy. A study in the exposure chamber. Allergo Journal International (2021).
2. Changes in the Mean and Variance of the Numbers of Medical Visits for Allergic Diseases before and during the COVID-19 Pandemic in Korea. Journal of Clinical Medicine (2022).
3. Hydroxypropylmethylcellulose gel application delays Der p 1 diffusion in vitro. Natural Science (2010).