Medication Adherence Strategies in Type 2 Diabetes Management

Summary

Effective management of type 2 diabetes hinges on sustained adherence to prescribed medications. Suboptimal adherence contributes to poor glycaemic control, heightened risk of complications and increased healthcare costs. Strategies to improve adherence are multifaceted, encompassing patient-centred education, simplification of drug regimens, behavioural support and use of digital technologies. Tailored counselling addresses individual barriers such as forgetfulness, concerns about side effects and financial constraints. Simplified dosing schedules and combination therapies reduce pill burden. Behavioural interventions draw on habit-formation techniques and social support networks to embed medication taking within daily routines. Digital health tools, including smartphone reminders and electronic monitoring, provide real-time feedback and motivational prompts. Health system approaches involve regular adherence assessment using metrics such as the medication possession ratio and integration of diabetes educators within primary care. Globally, efforts focus on vulnerable groups—patients with comorbidities, disabilities or limited health literacy—ensuring that interventions are culturally and contextually appropriate. The synergy of education, behavioural science and technology offers a pathway to durable medication adherence and improved long-term outcomes.

Research from Nature Portfolio

No recent Nature Portfolio content available.

Medication Adherence Strategies in Type 2 Diabetes Management publication trend

The graph below shows the total number of articles in medication adherence strategies in type 2 diabetes management across all publications each year (not limited to Nature Index journals).

Technical terms

Medication possession ratio (MPR): A quantitative measure of adherence reflecting the proportion of days’ supply obtained over a defined period.

Glycaemic control: The extent to which blood glucose levels are maintained within target ranges, often assessed by HbA1c measurements.

Comorbidity: The coexistence of one or more additional chronic health conditions alongside type 2 diabetes.

References

  1. Medication adherence in patients with type 2 diabetes after disability onset: a difference-in-differences analysis using nationwide data. BMC Medicine (2024).
  2. Factors Influencing Medication Adherence Among Adults Living with Diabetes and Comorbidities: a Qualitative Systematic Review. Current Diabetes Reports (2023).
  3. A Smartphone App to Improve Medication Adherence in Patients With Type 2 Diabetes in Asia: Feasibility Randomized Controlled Trial. JMIR mHealth and uHealth (2019).
Nature Strategy Reports
Turn complex research questions into confident strategic decisions 

When you're under pressure to set direction, justify investment, or understand your competitive position, you need more than raw data — you need trusted insights you can act on.

  • Benchmark your performance against global peers using robust, methodologically sound analysis.

  • Combine quantitative metrics with qualitative expert insight to uncover strengths, gaps and emerging opportunities.

  • Gain tailored, decision-ready recommendations aligned to your strategic priorities.

Talk to us to learn more about our data dashboards and bespoke strategy reports.

Nature Masterclasses
Grow research skills, confidence and careers with training built for every stage of the research lifecycle.

Developed with Nature Portfolio journal Editors and internationally renowned experts. Discover three ways to learn:

  • Self-paced, online courses in convenient bite-sized units, covering key skills across scientific writing, publishing, grant writing, data analysis, and more.

  • Expert trainer-led workshops with hands-on exercises and real-time feedback across core research skills, delivered via interactive group sessions.

  • Editor-led workshops combining core principles in writing and publishing, personalised 1:1 feedback from Nature Portfolio Editors and hands-on exercises.

Explore course catalogues and workshop agendas, enquire about the options or request institutional pricing.