Summary

The field of nanoenabled pesticide delivery systems leverages nanocarriers to optimise the delivery of active ingredients in agricultural settings. By encapsulating or adsorbing pesticides within nanoscale matrices—such as polymeric nanoparticles, mesoporous silica, lipid-based vesicles and supramolecular biopolymers—these systems offer controlled release, enhanced foliar adhesion and targeted action against pests and pathogens. Stimuli-responsive designs trigger release in response to pH, temperature, light or specific enzymes, minimising off-target losses and reducing environmental contamination. In addition to improving pesticide utilisation efficiency, nanoenabled platforms can lower required dosages, mitigate acute toxicity and address challenges associated with drift, leaching and photodegradation. This convergence of nanotechnology and agrochemistry supports sustainable crop protection by delivering bioactive compounds with greater precision, resilience under field conditions and adaptability to global agricultural demands.

Research from Nature Portfolio

Recent studies have demonstrated the potential of temperature-responsive copolymer carriers to improve droplet deposition and water resistance of fungicidal formulations. By employing rapid nanoparticle precipitation techniques, researchers produced leaf-adhesive nanoparticles that increased anti-wash efficiency by over 30% and reduced acute aquatic toxicity compared with conventional suspensions. In a separate approach, supramolecular vesicles incorporating photo-switchable host–guest complexes have been designed to encapsulate herbicidal agents, releasing them only upon exposure to ultraviolet or solar irradiation. These light-triggered systems achieved comparable weed-control performance to free herbicide while markedly improving safety profiles in model toxicity assays.

Nanoenabled Pesticide Delivery Systems publication trend

The graph below shows the total number of articles in nanoenabled pesticide delivery systems across all publications each year (not limited to Nature Index journals).

Technical terms

Nanocarrier: A nanoscale vehicle designed to encapsulate or bind active pesticide ingredients for delivery to specific sites.

Stimuli-responsive release: Controlled discharge of an active agent triggered by environmental cues such as pH, temperature, light or enzymes.

Supramolecular biopolymer: A polymeric network formed via non-covalent interactions, used to encapsulate and protect bioactive molecules.

Host–guest complex: A reversible assembly between two molecules where one (the host) forms a cavity to temporarily contain another (the guest), often used in light-triggered release.

Anti-wash efficiency: The capacity of a formulation to resist removal from leaf surfaces under rainfall or irrigation.

Photodegradation: The breakdown of compounds upon exposure to light, a process nanoenabled formulations aim to mitigate for sustained efficacy.

References

  1. Nano/Micro-Structural Supramolecular Biopolymers: Innovative Networks with the Boundless Potential in Sustainable Agriculture. Nano-Micro Letters (2024).
  2. Deposition and water repelling of temperature-responsive nanopesticides on leaves. Nature Communications (2023).
  3. Recent advances in stimuli-response mechanisms of nano-enabled controlled-release fertilizers and pesticides. Eco-Environment & Health (2023).
  4. Preparation of Multifunctional Nano‐Protectants for High‐Efficiency Green Control of Anthracnose. Advanced Science (2024).
  5. A user-friendly herbicide derived from photo-responsive supramolecular vesicles. Nature Communications (2018).
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