Optical Coherence Tomography Applications in Choroidal Osteoma
Summary
Optical coherence tomography has become integral to the evaluation of choroidal osteoma, a rare benign ossifying tumour of the choroid. By providing high-resolution, cross-sectional images, OCT reveals characteristic features of tumour composition, including intrinsic vascular networks, mineralised and decalcified regions, and overlying retinal alterations. Enhanced depth imaging and swept-source platforms extend penetration to the sclerochoroidal interface, delineating tumour thickness, structural heterogeneity and associated complications such as choroidal neovascularisation and subretinal fluid accumulation. OCT angiography further enables non-invasive mapping of intratumoural blood flow, distinguishing genuine tumour vasculature from secondary neovascular membranes. Together these modalities support early detection, longitudinal monitoring of growth and decalcification, and assessment of treatment response, including anti-angiogenic therapies and photodynamic interventions.
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Optical Coherence Tomography Applications in Choroidal Osteoma publication trend
The graph below shows the total number of articles in optical coherence tomography applications in choroidal osteoma across all publications each year (not limited to Nature Index journals).
Technical terms
Optical coherence tomography (OCT): non-invasive imaging modality that uses low-coherence light to generate high-resolution cross-sectional images of retinal and choroidal structures.
Swept-source OCT (SS-OCT): OCT variant employing a tunable laser source to increase imaging depth and speed, improving visualisation of deeper ocular tissues.
OCT angiography (OCTA): extension of OCT that detects motion contrast from blood cells to map retinal and choroidal vasculature without dye injection.
Choroidal neovascularisation (CNV): growth of new blood vessels from the choroid into subretinal spaces, often leading to exudation and vision loss.
Subretinal fluid (SRF): accumulation of fluid between the neurosensory retina and retinal pigment epithelium, indicating barrier disruption or vascular leakage.
Enhanced depth imaging (EDI-OCT): OCT technique that optimises focus and averaging near the choroid-scleral junction to enhance deep tissue resolution.
References
- Appearance of Tumor Vessels in Patients With Choroidal Osteoma Using Swept-Source Optical Coherence Tomographic Angiography. Frontiers in Oncology (2021).
- Clinical Observation of Choroidal Osteoma Using Swept-Source Optical Coherence Tomography and Optical Coherence Tomography Angiography. Applied Sciences (2022).
- Choroidal Osteoma With Choroidal Excavation Due to Decalcification Five Years After Photodynamic Therapy: A Case Report. Cureus (2024).
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