Orthopedic Surgical Outcomes in Parkinson's Disease
Summary
Parkinson’s disease imposes unique challenges for joint replacement, owing to motor impairment, altered balance and rigidity. Patients undergoing total knee or hip arthroplasty often experience meaningful pain relief and improved mobility, yet functional gains may be attenuated by progression of neurological disability. Complication profiles diverge from non-Parkinsonian cohorts, with increased incidence of medical events such as blood-loss anaemia and urinary tract infection, alongside mechanical complications including periprosthetic dislocations and fractures. Implant survivorship remains comparable in early stages, but long-term outcomes may decline with advancing disease. Preoperative optimisation, multidisciplinary coordination and tailored implant selection have emerged as critical factors to enhance safety and function in this population. Globally, these findings underscore the need for individualised surgical pathways to address the growing demographic of older adults with Parkinson’s disease requiring arthroplasty.
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Orthopedic Surgical Outcomes in Parkinson's Disease publication trend
The graph below shows the total number of articles in orthopedic surgical outcomes in parkinson's disease across all publications each year (not limited to Nature Index journals).
Technical terms
Total knee arthroplasty (TKA): Surgical replacement of the knee joint with a prosthetic implant.
Periprosthetic dislocation: Displacement of a joint implant from its intended anatomical position.
Prosthesis survivorship: Duration an implant remains functional without need for revision surgery.
Hoehn and Yahr scale: Clinical staging system to assess severity of Parkinson’s motor symptoms.
Constrained construct: Prosthetic design that provides additional mechanical stability to counteract joint instability.
References
- The effect of Parkinson’s disease on total knee arthroplasty: a systematic review and meta-analysis. Knee Surgery & Related Research (2023).
- Functional outcomes after total joint arthroplasty are related to the severity of Parkinson’s disease: a mid-term follow-up. Journal of Orthopaedic Surgery and Research (2019).
- Complications During the Hospital Stay, Length of Stay, and Cost of Care in Parkinson Patients Undergoing Total Knee Arthroplasty: A Propensity Matched Database Study. JAAOS Global Research and Reviews (2022).
- Treatment of Postoperative Instability Following Total Knee Arthroplasty in Patients With Parkinson’s Disease. Arthroplasty Today (2023).
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