Pasteurella Multocida Infections and Clinical Outcomes
Summary
Pasteurella multocida is a Gram-negative, facultatively anaerobic coccobacillus that colonises the upper respiratory tracts of a wide range of domestic and wild animals. Human infection typically follows animal bites, scratches or exposure to secretions, but may occasionally arise without overt trauma. Clinical manifestations range from localised soft-tissue inflammation to severe systemic disease, including bacteremia, pneumonia, endocarditis and infective aneurysms. Host factors such as advanced age, chronic liver disease, diabetes mellitus and immunosuppression greatly influence clinical severity and outcome. Prompt recognition, appropriate microbiological confirmation and early initiation of targeted antimicrobial therapy are critical to prevent progression to complications such as septic shock or deep-seated abscess formation. Globally, rising pet ownership and an ageing population with comorbidities have increased the incidence and complexity of P. multocida infections, underscoring the need for heightened clinical vigilance and tailored management strategies.
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Pasteurella Multocida Infections and Clinical Outcomes publication trend
The graph below shows the total number of articles in pasteurella multocida infections and clinical outcomes across all publications each year (not limited to Nature Index journals).
Technical terms
Zoonosis: Infection transmitted from animals to humans.
Bacteremia: Presence of bacteria in the bloodstream.
Septic shock: A life-threatening circulatory and metabolic disorder caused by overwhelming infection.
Coccobacillus: A bacterial shape intermediate between cocci (spherical) and bacilli (rod-shaped).
Comorbidity: The coexistence of two or more chronic medical conditions in a patient.
References
- Bloodstream infection, peritonitis, and pneumonia caused by Pasteurella multocida in a patient with liver cirrhosis despite no animal contact: case report and literature review. Frontiers in Cellular and Infection Microbiology (2023).
- Pasteurella Multocida Infection in Humans. Pathogens (2023).
- Pasteurella species bloodstream infections in Queensland, Australia, 2000–2019. European Journal of Clinical Microbiology & Infectious Diseases (2022).
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