Phytochemical Properties and Therapeutic Applications of Corn Silk
Summary
Corn silk, the thread-like styles from Zea mays L., has emerged from traditional herbal lore to a subject of rigorous scientific enquiry. Phytochemical analyses have revealed a rich tapestry of bioactive constituents, notably flavonoids, phenolic acids, phytosterols and alkaloids. These compounds underpin diverse pharmacological activities including antioxidant, anti-inflammatory, diuretic and glycaemic-modulating effects. Mechanistic studies suggest that flavonoid-mediated scavenging of reactive oxygen species and modulation of cellular signalling pathways contribute to protection against oxidative stress and inflammation. In vitro and in vivo models have further elucidated hypoglycaemic actions via enhanced insulin secretion and pancreatic β-cell preservation, as well as antihypertensive and lipid-lowering potentials. Emerging evidence also indicates antimicrobial and antiproliferative properties, broadening the spectrum of possible applications. Together, these findings support the prospect of corn silk as a sustainable source of therapeutic agents and functional food ingredients, with global relevance for metabolic and inflammatory disorders.
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Phytochemical Properties and Therapeutic Applications of Corn Silk publication trend
The graph below shows the total number of articles in phytochemical properties and therapeutic applications of corn silk across all publications each year (not limited to Nature Index journals).
Technical terms
Phytochemicals: plant-derived bioactive compounds such as flavonoids, terpenoids and sterols.
Flavonoids: a class of polyphenolic compounds widely distributed in plants, noted for their antioxidant and anti-inflammatory effects.
Phenolic compounds: plant secondary metabolites characterised by one or more hydroxyl groups attached to an aromatic ring, contributing to antioxidative properties.
Reactive oxygen species (ROS): highly reactive molecules containing oxygen, which can induce oxidative stress in biological systems.
Antioxidant activity: the capacity of a substance to scavenge free radicals or inhibit oxidative processes.
References
- Recent Advances in the Extraction and Characterization of Bioactive Compounds from Corn By-Products. Antioxidants (2024).
- Phytochemical Analysis and Characterization of Corn Silk (Zea mays, G5417). Agronomy (2022).
- Extraction of Flavonoids from Corn Silk and Biological Activities In Vitro. Journal of Food Quality (2021).
- Corn Silk (Stigma Maydis) in Healthcare: A Phytochemical and Pharmacological Review. Molecules (2012).
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