Summary

Psychosocial care in cancer survivorship encompasses the emotional, social and psychological support provided to individuals from diagnosis through post-treatment and beyond. Survivors often face depression, anxiety and fear of recurrence, which can undermine quality of life, adherence to follow-up and overall health. Effective care integrates routine screening for emotional distress, evidence-based psychological therapies, peer and family support, and self-management resources. Multidisciplinary teams collaborate to address individual needs, drawing on cognitive behavioural approaches, acceptance and commitment strategies and culturally sensitive digital programmes. Global challenges include unequal access to services, cultural and linguistic barriers and the need for sustainable models for long-term psychosocial follow-up. Recent advances highlight the promise of virtual platforms to extend supportive care and the importance of early identification of survivors at high risk of chronic distress.

Research from Nature Portfolio

Recent studies have illuminated the link between mood and cancer therapy response. A prospective observational study in patients with advanced non-small-cell lung cancer showed that those with baseline emotional distress, identified by standardised depression and anxiety scales, experienced significantly shorter progression-free survival and lower response rates to immune checkpoint inhibitors. Elevated cortisol in distressed patients pointed to a psychoneuroendocrine mechanism affecting treatment efficacy. In breast cancer survivorship, a randomised trial tested a culturally tailored virtual information and coaching programme for Asian American women. Over 12 weeks the intervention group reported marked reductions in unmet supportive care needs and meaningful gains in quality of life compared with controls using only standard resources, demonstrating the value of digitally delivered, culturally adapted support.

Psychosocial Care in Cancer Survivorship publication trend

The graph below shows the total number of articles in psychosocial care in cancer survivorship across all publications each year (not limited to Nature Index journals).

Technical terms

Emotional distress: A state of psychological suffering characterised by symptoms of depression and anxiety.

Immune checkpoint inhibitors: Drugs that enhance antitumour immunity by blocking inhibitory pathways such as PD-1 or CTLA-4.

Culturally tailored intervention: A support programme adjusted to the cultural values and practices of a specific population to improve relevance and engagement.

Fear of cancer recurrence (FCR): Persistent worry or concern that cancer will return or progress after treatment.

Cognitive behavioural therapy (CBT): A structured psychological treatment targeting dysfunctional thoughts and behaviours to reduce distress.

References

  1. Association between pretreatment emotional distress and immune checkpoint inhibitor response in non-small-cell lung cancer. Nature Medicine (2024).
  2. A randomized controlled trial testing a virtual program for Asian American women breast cancer survivors. Nature Communications (2023).
  3. Depression and anxiety among people living with and beyond cancer: a growing clinical and research priority. BMC Cancer (2019).
  4. Effect of Psychological Intervention on Fear of Cancer Recurrence: A Systematic Review and Meta-Analysis. Journal of Clinical Oncology (2019).
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